scholarly journals Three years with a knife stuck in the brain

2014 ◽  
Vol 33 (03) ◽  
pp. 192-196
Author(s):  
Luiz Coutinho Dias Filho ◽  
Alex Caetano de Barros ◽  
Marina Félix da Mota

AbstractCranial stabbing injuries penetrating the brain are not commonly encountered. The cases in which the knife is retained constitute a challenge to the neurosurgeon. When a long-term permanence occurs, the reaction to the presence of the foreign body causes adherence to the nervous tissue and a higher risk is expected from the removal. The procedure should be performed with meticulous dissection and minimal oscillation of the blade thus avoiding damage to the adjacent structures. We report a case of a man who remained three years with a knife blade deeply lodged in the brain. After obtaining informed consent, the blade was removed; there were no postoperative complications. To our knowledge, this is the first case in which, after years of permanence, a knife blade was removed from the brain through a craniotomy.

1988 ◽  
Vol 102 (2) ◽  
pp. 190-193 ◽  
Author(s):  
A. Poukkula ◽  
E.-M. Ruotsalainen ◽  
K. Jokinen ◽  
A. Palva ◽  
J. Nuorviita

AbstractTwo cases are reported in which a denture fragment was lodged in the bronchus for a period of six years. Bronchial asthma which did not worsen immediately after inhalation and other misleading factors made the diagnosis more difficult in the first case, whilst the respiratory symptoms in the second case appeared only 4 years after inhalation. Haemoptysis 2 years later led to a bronchoscopy and the removal of the foreign body.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Seongjun Park ◽  
Hyunwoo Yuk ◽  
Ruike Zhao ◽  
Yeong Shin Yim ◽  
Eyob W. Woldeghebriel ◽  
...  

AbstractTo understand the underlying mechanisms of progressive neurophysiological phenomena, neural interfaces should interact bi-directionally with brain circuits over extended periods of time. However, such interfaces remain limited by the foreign body response that stems from the chemo-mechanical mismatch between the probes and the neural tissues. To address this challenge, we developed a multifunctional sensing and actuation platform consisting of multimaterial fibers intimately integrated within a soft hydrogel matrix mimicking the brain tissue. These hybrid devices possess adaptive bending stiffness determined by the hydration states of the hydrogel matrix. This enables their direct insertion into the deep brain regions, while minimizing tissue damage associated with the brain micromotion after implantation. The hydrogel hybrid devices permit electrophysiological, optogenetic, and behavioral studies of neural circuits with minimal foreign body responses and tracking of stable isolated single neuron potentials in freely moving mice over 6 months following implantation.


2020 ◽  
Author(s):  
Edward Zhang ◽  
Alia Alameri ◽  
Jean-Pierre Clement ◽  
Andy Ng ◽  
Timothy E Kennedy ◽  
...  

Brain implants are increasingly used to treat neurological disorders and diseases. However, the brain foreign body response (FBR) elicited by implants affects neuro-electrical transduction and long-term reliability limiting their clinical adoption. The mismatch in Young's modulus between silicon implants (~180 GPa) and brain tissue (~1-30 kPa) exacerbates the FBR resulting in the development of flexible implants from polymers such as polyimide (~1.5-2.5 GPa). However, a stiffness mismatch of at least two orders of magnitude remains. Here, we introduce (i) the first mechanically matched brain implant (MMBI) made from silicone (~20 kPa), (ii) new microfabrication methods, and (iii) a novel dissolvable sugar shuttle to reliably implant MMBIs. MMBIs were fabricated via vacuum-assisted molding using sacrificial sugar molds and were then encased in sugar shuttles that dissolved within 2 min after insertion into rat brains. Sections of rat neocortex implanted with MMBIs, PDMS implants, and silicon implants were analyzed by immunohistochemistry 3 and 9-weeks post-implantation. MMBIs resulted in significantly higher neuronal density and lower FBR within 50 μm of the tissue-implant interface compared to PDMS and silicon implants suggesting that materials mechanically matched to brain further minimize the FBR and could contribute to better implant functionality and long-term reliability.


Author(s):  
Mimouni Hicham ◽  
Touihmi Safaa ◽  
Rkain Ilham

<p class="abstract">Granular cell tumors also named Abrikossoff’s tumors, are very rare soft tissue tumors, almost always benign and can affect different organs. The head and neck location are the most common, particularly skin and the tongue. The larynx is concerned in 7 to 10% of the cervico-facial locations of this tumor (1, 2). In this article we report two cases of Abrikossoff’s tumor. The first case is of a 27 years old man, with no particular features in his medical history, who consulted for dysphonia, progressively evolving over 6 months. The nasal endoscopy found a whitish nodular lesion of almost 20 mm of diameter, involving the middle third of the right vocal cord. The tumor was removed under microlaryngoscopy. The second case is of ten days old newborn female, who presented dyspnea and dysphagia while breastfeeding, the clinical exam showed a round shaped lesion of 4 cm of diameter, implanted in the dorsal face of the tongue. The lesion was rooted out with electrocautery under general anesthesia. Anatomopathology examination with Immunohistochemistry of both patients’ surgical samples confirmed the diagnosis of granular cell tumor. The Origin of the Abrikossof’s tumors is uncertain. The recent immunohistochemical studies are orienting toward neurogenic origin. These tumors usually arise in the adult, between the ages of 20 to 60 years old, with female predominance. The symptoms are diverse and non-specific, only the anatopahtological examination permits to confirm the diagnosis. The main issues of these tumors are the compression of the adjacent structures and the high risk of recurrence, which requires long term surveillance.</p>


2017 ◽  
Vol 31 (4) ◽  
pp. 560-563
Author(s):  
Luis Rafael Moscote-Salazar ◽  
Amit Agrawal ◽  
Marticela Cabeza-Morales ◽  
Nasly Zabaleta-Churio ◽  
Willem Guillermo Calderon-Miranda ◽  
...  

Abstract Intracranial foreign bodies are rare events that occur accidentally and depending on the extent and involvement of the brain parenchymal, generate focal neurological deficit, bleeding and even long-term complications. In present article we describe a case of 4 year child and discuss the approach, management and prognosis.


2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Safak Karacay ◽  
Koray Topçu ◽  
Selami Sözübir

We present a 13-year-old child who admitted with a dull right upper quadrant pain that started 3 weeks before her referral. Several medications were given but they did not change the intensity and the frequency of the pain. Her physical examination was nonspecific except for slight right upper quadrant tenderness. The imaging studies revealed a sewing pin perforating the stomach and gallbladder. The patient was treated with a successful operation, and no postoperative complications were observed. To our knowledge, this is the first case of a sharp foreign body gallbladder perforation in a child.


2021 ◽  
Vol 5 (4) ◽  
Author(s):  
Aisyah Amirah binti Mohd Zahari ◽  
Firdaus Ujang

Background: Intraocular foreign body (IOFB) is a common ocular trauma and is a leading cause of visual impairment. Majority of the cases reported the occurrence at the workplace and usually related to activities involving metallic objects. Hammering, drilling, explosion and usage of machining tools are among the causes of IOFB. Foreign body in the angle are frequently missed as it is not visualised directly during a routine examination. Thus, a thorough examination which includes gonioscopy and imaging must be done in all penetrating and full thickness cornea laceration cases. Purpose: We report a case of self-sealed full thickness cornea laceration with presence of metal foreign body in the angle. Method: Case Report Result: A 19 year-old boy, presented with right eye discomfort following trauma 1 week prior to presentation. Examination revealed a self-sealed full thickness cornea laceration at 1-2 o’clock with a foreign body found seated on the angle from gonioscopy. A foreign body consist of metal had successfully removed surgically with the facilitation of intraocular magnet. Conclusion: All self-sealed penetrating injury to the eye required a high index of suspicious of intraocular foreign body. An imaging and complete examination with dilated fundus examination and gonioscopy will be helpful to identify the location of foreign body. Hence, definitive treatment will prevent long term complication related to intraocular foreign body.


2014 ◽  
Vol 142 (7-8) ◽  
pp. 464-467 ◽  
Author(s):  
Nenad Zivkovic ◽  
Iva Berisavac ◽  
Marko Markovic ◽  
Sanja Milenkovic

Introducion. Intracranial chondroma is a very rare, slow growing, benign cartilaginous tumor that arises usually from the base of the scull. Chondroma located at the falx is extremely rare. According to our best knowledge 15 cases of falx chondromas have been reported in the literature. Case Outline. This is the first case report of falx chondroma located in the parietal area associated with hyperostosis. Magnetic resonance imaging of the brain revealed a 3?4?4 cm solid, calcified, ring-shaped, well-defined tumor at the posterior falx. The patient underwent surgery and complete resection was performed. Histological examination confirmed chondroma of the falx. Postoperative CT scan showed no residual of tumor and the patient was discharged. Conclusion. The long-term prognosis is good after a total excision of the tumor. Awareness of this rare pathology in the differential diagnosis of falx mass could facilitate the diagnosis.


2010 ◽  
Vol 24 (4) ◽  
pp. 249-252 ◽  
Author(s):  
Márk Molnár ◽  
Roland Boha ◽  
Balázs Czigler ◽  
Zsófia Anna Gaál

This review surveys relevant and recent data of the pertinent literature regarding the acute effect of alcohol on various kinds of memory processes with special emphasis on working memory. The characteristics of different types of long-term memory (LTM) and short-term memory (STM) processes are summarized with an attempt to relate these to various structures in the brain. LTM is typically impaired by chronic alcohol intake but according to some data a single dose of ethanol may have long lasting effects if administered at a critically important age. The most commonly seen deleterious acute effect of alcohol to STM appears following large doses of ethanol in conditions of “binge drinking” causing the “blackout” phenomenon. However, with the application of various techniques and well-structured behavioral paradigms it is possible to detect, albeit occasionally, subtle changes of cognitive processes even as a result of a low dose of alcohol. These data may be important for the consideration of legal consequences of low-dose ethanol intake in conditions such as driving, etc.


Author(s):  
Peter R. Breggin

BACKGROUND: The vaccine/autism controversy has caused vast scientific and public confusion, and it has set back research and education into genuine vaccine-induced neurological disorders. The great strawman of autism has been so emphasized by the vaccine industry that it, and it alone, often appears in authoritative discussions of adverse effects of the MMR and other vaccines. By dismissing the chimerical vaccine/autism controversy, vaccine defenders often dismiss all genuinely neurological aftereffects of the MMR (measles, mumps, and rubella) and other vaccines, including well-documented events, such as relatively rare cases of encephalopathy and encephalitis. OBJECTIVE: This report explains that autism is not a physical or neurological disorder. It is not caused by injury or disease of the brain. It is a developmental disorder that has no physical origins and no physical symptoms. It is extremely unlikely that vaccines are causing autism; but it is extremely likely that they are causing more neurological damage than currently appreciated, some of it resulting in psychosocial disabilities that can be confused with autism and other psychosocial disorders. This confusion between a developmental, psychosocial disorder and a physical neurological disease has played into the hands of interest groups who want to deny that vaccines have any neurological and associated neuropsychiatric effects. METHODS: A review of the scientific literature, textbooks, and related media commentary is integrated with basic clinical knowledge. RESULTS: This report shows how scientific sources have used the vaccine/autism controversy to avoid dealing with genuine neurological risks associated with vaccines and summarizes evidence that vaccines, including the MMR, can cause serious neurological disorders. Manufacturers have been allowed by the US Food and Drug Administration (FDA) to gain vaccine approval without placebo-controlled clinical trials. CONCLUSIONS: The misleading vaccine autism controversy must be set aside in favor of examining actual neurological harms associated with vaccines, including building on existing research that has been ignored. Manufacturers of vaccines must be required to conduct placebo-controlled clinical studies for existing vaccines and for government approval of new vaccines. Many probable or confirmed neurological adverse events occur within a few days or weeks after immunization and could be detected if the trials were sufficiently large. Contrary to current opinion, large, long-term placebo-controlled trials of existing and new vaccines would be relatively easy and safe to conduct.


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