Relationship Between Platelet Adhesion And Free Energies At Solid-Liquid Interfaces

1981 ◽  
Author(s):  
Donald J L McIver ◽  
Samuel Schürch
Keyword(s):  
Thrombus Formation ◽  
Lower Surface ◽  
Liquid Interfaces ◽  
Free Energies ◽  
Surface Wetting ◽  
Interfacial Energies ◽  
Synthetic Coating ◽  
Foreign Surface ◽  
Solid Liquid ◽  
Lower Surface Energy

Surface induced thrombosis remains an obstacle to extra-corpeal circulation and invasive investigation and therapy of the cardiovascular system. Although the molecular details of the blood-foreign surface interaction remain incompletely understood, from a thermodynamic viewpoint, thrombosis can only occur if thrombus formation lowers the free energy of the blood-surface system. We have recently reported a method of estimating surface free energies under physiological conditions from measurements of surface wetting by polar hydrophobic fluids. Here we report a correlation between interfacial energies and platelet retention on natural and artificial surfaces, and the effects on platelet retention of a synthetic coating developed in an attempt to mimic the thromboresistance of healthy endothelium. This coating has a lower surface energy than the artery and it appears to be equally thromboresistant.

Adsorption of surfactants at solid/liquid interfaces

Surfactants ◽  
2019 ◽  
pp. 130-155
Author(s):  
Bob Aveyard
Keyword(s):  
Strong Influence ◽  
Langmuir Equation ◽  
Solid Surfaces ◽  
Polymeric Surfactant ◽  
Fluid Interfaces ◽  
Liquid Interfaces ◽  
Free Energies ◽  
Micellar Aggregates ◽  
Diffuse Part ◽  
Solid Liquid

The physical properties of solid/liquid interfaces are more diverse than those of liquid/fluid interfaces, and consequently the interactions giving rise to adsorption of surfactant or polymeric surfactant are more varied. Solid surfaces can be either hydrophilic or hydrophobic, the former being water-wetted and containing polar or ionogenic sites. Electrical charge at the solid surface is neutralized by ions in the inner and outer Helmholtz planes and in the diffuse part of the electrical double layer. Surface charge has a strong influence on adsorption of ionic surfactants. Standard free energies of surfactant adsorption are obtained by use of an appropriate adsorption isotherm such as the Stern–Langmuir equation. Micellar aggregates of various shapes and sizes can also form at solid/liquid interfaces.

Quantitative Evaluation of the Interfacial Free Energies at A Solid-Liquid Lamellar Eutectic Interface

1981 ◽  
Vol 12 ◽  
Author(s):  
W. F. Kaukler ◽  
J. W. Rutter
Keyword(s):  
Free Energy ◽  
Solid Phase ◽  
Interfacial Free Energy ◽  
Eutectic System ◽  
Liquid Interfaces ◽  
Free Energies ◽  
Two Phases ◽  
Interfacial Free Energies ◽  
The Individual ◽  
Solid Liquid

The solid-liquid interfacial free energies of each of the individual phases comprising the eutectic system, Carbon Tetrabromide-Hexachloroethane, were measured as a function of composition using a “grain boundary groove” technique. Thermodynamic data were combined with groove shape measurements made from high resolution optical photomicrographs of the solid-liquid interfaces to give the interfacial free energy data. An interfacial free energy balance at the eutectic trijunction was performed to obtain all the forces acting on that point. The three interphase interfacial free energies at the eutectic trijunctions as well as a solid-solid phase boundary torque were evaluated.It was found that the solid-liquid interfacial free energies of the two phases of the eutectic could be evaluated from photomicrographs of growing or stationary eutectic interfaces. In addition, it was found that for a substantial range of freezing conditions the eutectic interface shape can be predicted from a knowledge of the interfacial free energies alone.

The equilibrium shapes of small liquid droplets in solid–liquid phase mixtures: metallic h.c.p. and metalloid systems

1969 ◽  
Vol 312 (1509) ◽  
pp. 257-276 ◽  
Keyword(s):  
Free Energy ◽  
Interfacial Free Energy ◽  
Interfacial Structure ◽  
Liquid Droplets ◽  
Liquid Interfaces ◽  
Spherical Droplet ◽  
Factors Affecting ◽  
Interfacial Energies ◽  
Equilibrium Shapes ◽  
Solid Liquid

Solid–liquid interfacial free energy is shown to be highly anisotropic in alloys of some h. c. p. metals and of two metalloids. This anisotropy is evaluated from a study of the equilibrium shapes of small droplets of alloy liquid entrained within solid grains. Factors affecting the attainment of equilibrium in such droplets are considered, and γ -plots are obtained for solid–liquid interfaces in the h. c. p. metals zinc and cadmium. In the magnesium alloys studied, spherical droplet shapes were observed, indicative of essentially isotropic interfacial energies. Droplet shapes were also analysed in some alloys of bismuth and of antimony. The results are related to current ideas of solid–liquid interfacial structure.

scholarly journals Solvation free energies for periodic surfaces: comparison of implicit and explicit solvation models

2016 ◽  
Vol 18 (46) ◽  
pp. 31850-31861 ◽  
Author(s):  
Stephan N. Steinmann ◽  
Philippe Sautet ◽  
Carine Michel
Keyword(s):  
Free Energy ◽  
Liquid Interfaces ◽  
Free Energies ◽  
Periodic Surfaces ◽  
Solvation Energies ◽  
Solvation Models ◽  
Implicit And Explicit ◽  
Solvation Free Energies ◽  
Solid Liquid ◽  
Explicit Solvation

A strategy based on molecular mechanics free energy of perturbation, seeded by quantum mechanics, is presented to take solvation energies into account in the context of periodic, solid–liquid interfaces.

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