scholarly journals Landmark Trials in Cardiology in 2017—Celebrating 40 Years of Angioplasty

2018 ◽  
Vol 27 (03) ◽  
pp. 167-173
Author(s):  
Pravesh Vishwakarma ◽  
Rishi Sethi ◽  
Akshyaya Pradhan
Keyword(s):  
Daily Practice ◽  
Coronary Intervention ◽  
Positive Outcomes ◽  
Coronary Syndrome ◽  
The Past ◽  
Percutaneous Coronary ◽  
Wide Range ◽  
Artery Disease ◽  
Based Medicine ◽  
Made In

AbstractCardiovascular (CV) diseases continue to be the leading cause of morbidity and mortality worldwide. Significant progress has been made in the management of coronary artery disease (CAD) and acute coronary syndrome (ACS) over the past 3 decades. The year 2017 marks 40th anniversary of the first coronary angioplasty performed by Andreas Gruentzig in the year 1977. Evidence-based medicine and research has been the key driving force of these positive outcomes. The year 2017 witnessed presentation of several landmark studies at major meetings and many of them getting published in literature simultaneously. These trials evaluated wide range of issues from novel percutaneous coronary intervention (PCI) strategies to newer drugs to innovative devices in management of CAD. We selectively discuss a few major landmark studies that have the potential to alter our daily practice in 2018.

scholarly journals Case ReportsClinical effect of ivabradine in patient with congestive heart failure with cardiogenic shock condition: A case reportAcute mesenteric ischemia on extensive anterior STEMI with paroxysmal atrial fibrilation: A rare complicationAcute fulminant myocarditis mimicking ST-elevation myocardial infarctionFractional flow reserve: Nurturing a functional perspective in angioplasty (Case Report)The role of invasive fractional flow reserve (FFR) in multivessel diseaseFibrinolytic followed by early angiography in cardiac arrest survivor patients with ST elevation ACS: A pharmaco-invasive in non-primary PCI capable hospitalEarly accelerated idioventricular rhythm followed by premature ventricular complexes as a marker for successful reperfusion in ST-elevation myocardial infarct patientInferior ST-elevation myocardial infarction complicated by unstable total atrioventricular block and diabetic ketoacidosis in end stage renal failure patientOutlflow tract ventricular arrythmia 3D ablation in LV summit Area: A case reportIntravascular hemolysis complication after transcatheter PDA closure with ADO device: A case reportA very rare case: A patient with extreme levocardia without remarkable symptomTransradial primary percutaneous coronary intervention on a patient with ST-Elevation myocardial infarction with comorbid peripheral artery disease and severe partial obstruction in the abdominal aortaAcute coronary syndrome with ventricular stormCardio-cerebral infaction: A rare case of concomitant acute right ventricular infarction and ischemic strokeTypical ECG pattern of acute pulmonary embolism in a 45 years old dyspneic and chest pain male patient: A case reportPersistent high degree AV block after early invasive strategy in acute decompensated heart failure caused by NSTEMI: A case reportAdult patent ductus arteriosus complicated by pulmonary artery endarteritis and pneumoniaRoutine thrombus aspiration in primary percutaneous coronary intervention: Is it still necessary? (Case Report)Curable severe tachycardiomyopathy due to typical atrial flutter by radiofrequency catheter ablationSinus node dysfunction in right heart failure: A rare caseLipomatous hypertrophy of the interatrial expanding into left atrial appendage mimicking thrombus: A very rare case reportConservative approach for patient in acute heart failure with cor triatriatum dexter and atrial fibrillation: A rare case reportAcute rheumatic fever in juvenile complicated by complete heart block: A case reportA nineteen years old young woman with idiopathic hypertrophic subaortic stenosis: A case reportRecurrent acute coronary syndrome – a manifestation of clopidogrel resistance: A case reportSubarterial doubly committed ventricularseptal defectcomplicated with right-sided fungalinfective endocarditisCase report: The hemodynamic effect of non invasive ventilation in atrial septal defect with severe pulmonary hypertension and respiratory failureEchocardiography-guided percutaneus transvenous mitral commissurotomy in a pregnant woman with severe mitral stenosisThe correlation between endothelial function parameter flow mediated vasodilatation with the complexity of coronary artery disease based on Syntax ScoreRuptured sinuses of valsalva aneurysms: Report of five casesParacetamol as alternative for patent ductus arteriosus (PDA) management

2016 ◽  
Vol 18 (suppl B) ◽  
pp. B51-B57 ◽  
Author(s):  
A. Widya ◽  
A. Jalaludinsyah ◽  
D.G. Widyawati ◽  
E. Hindoro ◽  
E. Supriadi ◽  
...  
Keyword(s):  
Heart Failure ◽  
Rare Case ◽  
Ductus Arteriosus ◽  
Coronary Intervention ◽  
Coronary Syndrome ◽  
Flow Reserve ◽  
Percutaneous Coronary ◽  
St Elevation ◽  
Artery Disease ◽  
Patent Ductus

scholarly journals Subanalysis of the AUGUSTUS trial

2020 ◽  
Vol 25 ◽  
pp. 4104
Author(s):  
T. V. Pavlova ◽  
P. D. Duplyakova ◽  
O. V. Shkaeva ◽  
S. P. Krivova
Keyword(s):  
Acute Coronary Syndrome ◽  
Large Scale ◽  
Coronary Intervention ◽  
The Novel ◽  
Actual Clinical Practice ◽  
Coronary Syndrome ◽  
Hospitalization Rates ◽  
Percutaneous Coronary ◽  
Artery Disease ◽  
European Society Of Cardiology

Comorbidity is a common feature of a modern patient. The combination of atrial fibrillation (AF) and various types of coronary artery disease is widespread in actual clinical practice. In such cases, additional pathophysiological mechanisms appear that worsen the clinical course and patient’s prognosis. The management of AF patients who have undergone acute coronary syndrome and/or percutaneous coronary intervention is a challenging problem, which can be solved by large-scale clinical trials. The AUGUSTUS randomized trial with a two-by-two factorial design proved that full-dose apixaban is superior in safety to the vitamin K antagonist warfarin, while not inferior in effectiveness. This pattern has been preserved in several important subanalysis on stent thrombosis, hospitalization rates, and conservative management of acute coronary syndrome. The obtained results are included in the novel European Society of Cardiology guidelines on AF.

scholarly journals Middle-aged man who could not afford an angioplasty

2019 ◽  
Vol 12 (3) ◽  
pp. e227118
Author(s):  
Vivek Podder ◽  
Amy Price ◽  
Madhava Sai Sivapuram ◽  
Rakesh Biswas
Keyword(s):  
Financial Risk ◽  
Coronary Intervention ◽  
Evidence Based ◽  
Shared Decision ◽  
For Profit ◽  
Inappropriate Use ◽  
Percutaneous Coronary ◽  
Artery Disease ◽  
Recent Acute Myocardial Infarction ◽  
Based Medicine

Coronary artery disease managed by percutaneous coronary intervention (PCI) has been noted for profit-driven overuse medicine. Concerns mount over inappropriate use of PCI for patients in India. We describe the case of a 55-year-old Indian man who presented for a second opinion following an urgent recommendation for PCI by two cardiologists following a recent acute myocardial infarction even though the patient was symptom-free and out of the window period for primary PCI. The proposed intervention placed the patient at financial risk for insolvency. This case report highlights the challenges and consequences of inappropriate overuse of PCI. Also, we outline the current lack of shared decision-making among patients and physicians for the PCI procedure. The challenges, inherent in the assumptions that overuse of PCI is evidence-based, are discussed including recommendations for the practice of evidence based medicine for this intervention.

scholarly journals Left brachial artery: one more way to percutaneous insertion of IMPELLA 2.5L circulatory support for high-risk percutaneous coronary intervention – a case report

2020 ◽  
Author(s):  
Paolo Sganzerla ◽  
Francesco Cinelli ◽  
Andrea Capoferri ◽  
Mauro Rondi
Keyword(s):  
Percutaneous Coronary Intervention ◽  
High Risk ◽  
Circulatory System ◽  
Common Femoral Artery ◽  
Coronary Intervention ◽  
Left Ventricular ◽  
Circulatory Support ◽  
Coronary Syndrome ◽  
Percutaneous Coronary ◽  
Artery Disease

Abstract Background Percutaneous circulatory support allows the performance of coronary interventions in ever more complex anatomic and clinical situations. The large-bore systems currently available need a suitable vascular calibre to be inserted restricting percutaneous access mainly to the common femoral artery. Case summary We present the case of a 64-year-old man, admitted with an acute coronary syndrome and congestive heart failure, due to triple-vessel coronary artery disease with left main involvement and left ventricular dysfunction. He was successfully treated with percutaneous coronary intervention (PCI) supported through an IMPELLA 2.5L circulatory system. Concomitant severe and diffuse peripheral vascular disease did not allow femoral insertion of the circulatory support which was therefore successfully introduced through a left brachial percutaneous approach. Discussion To the best of our knowledge, this is the first report of a brachial, percutaneous placement of the IMPELLA 2.5L system to support a high-risk PCI procedure. In appropriately selected patients, this approach could be an option when common vascular accesses are not available.

scholarly journals Carotid or Coronary Intervention which is to be done First?

2016 ◽  
Vol 01 (04) ◽  
pp. 095-097
Author(s):  
Ravikiran M. ◽  
Jabeen Afshan ◽  
Nemani Lalita
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Surgery ◽  
Carotid Artery Disease ◽  
Artery Bypass ◽  
Significant Coronary Artery Disease ◽  
Coronary Intervention ◽  
Carotid Disease ◽  
The Past ◽  
Percutaneous Coronary ◽  
Artery Disease

AbstractIn carotid artery disease patients with concomitant significant coronary artery disease (CAD - especially left main diseases – LMCA), the risk of perioperative myocardial infarction and early and late death are increased. Conversely, in patients undergoing coronary artery bypass surgery (CABG), uncorrected severe carotid disease increases the risk of adverse neurologic events [1]. The optimal management of these co-existing conditions and the timing and sequence of correcting them remain controversial. Over the past 2 decades, staged carotid revascularisation followed by CABG, staged CABG followed by carotid revascularisation, or combined coronary and carotid revascularisation simultaneously in one operative setting have each been advocated. Our patient presented with both carotid and significant LMCA CAD, first we have done carotid intervention followed one week later by LMCA percutaneous coronary intervention (PCI).

scholarly journals Quality of life after myocardial re-vascularisation in patients with acute coronary syndrome during the coronavirus disease 2019 pandemic: a prospective observational study

2021 ◽  
Vol 25 (4) ◽  
pp. 64
Author(s):  
A. S. Klinkova ◽  
O. V. Kamenskaya ◽  
I. Yu. Loginova ◽  
A. M. Chernyavskiy ◽  
V. V. Lomivorotov
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Coronary Intervention ◽  
Coronary Syndrome ◽  
Percutaneous Coronary ◽  
Artery Disease

<p><strong>Aim.</strong> To study the quality of life and how it is influenced by different factors in the long term after myocardial re-vascularisation in patients with coronary artery disease who had acute coronary syndrome during the coronavirus disease 2019 (COVID-19) pandemic.</p><p><strong>Methods.</strong> We examined 658 patients with coronary artery disease and acute coronary syndrome (mean age 66.4 ± 4.3 years). Percutaneous coronary intervention (600 patients) and coronary artery bypass grafting with cardio-pulmonary bypass (58 patients) were performed. Six months after myocardial re-vascularisation, we assessed patients' quality of life using the SF-36 questionnaire. We identified factors that affect the quality of life using multivariate regression analysis.</p><p><strong>Results.</strong> After myocardial revascularisation, the patients had a reduced overall indicator of physical health (&lt; 40 points). The overall indicator of psycho-emotional health was higher than physical (p &lt; 0.002) but did not exceed 50 points. We noted the adverse effect of COVID-19 (regardless of disease severity) on the assessment. Also, COVID-19 was associated with increased anxiety. A history of concomitant diabetes mellitus, obesity, stroke and percutaneous coronary intervention had a negative effect on the overall indicators of physical and mental health.</p><p><strong>Conclusion. </strong>Patients with coronary artery disease who had acute coronary syndrome after myocardial re-vascularisation are characterised by reduced indicators of physical and average indicators of mental health in the long term. COVID-19, regardless of disease severity, has a negative impact on patients' general state of health, social activity and emotional background. A history of diabetes mellitus, obesity, stroke and percutaneous coronary intervention adversely affects the physical and mental health indicators.</p><p>Received 4 August 2021. Revised 31 August 2021. Accepted 1 September 2021.</p><p><strong>Funding:</strong> This work was carried out within the framework of the state task of the Ministry of Health of the Russian Federation (No. 121031300225-8).</p><p><strong>Conflict of interest:</strong> Authors declare no conflict of interest.</p><p><strong>Contribution of the authors<br /> </strong>Conception and study design: O.V. Kamenskaya, V.V. Lomivorotov<br /> Data collection and analysis: A.S. Klinkova<br /> Statistical analysis: A.S. Klinkova<br /> Drafting the article: A.S. Klinkova, I.Yu. Loginova<br /> Critical revision of the article: O.V. Kamenskaya, A.M. Chernyavskiy<br /> Final approval of the version to be published: A.S. Klinkova, O.V. Kamenskaya, I.Yu. Loginova, A.M. Chernyavskiy, V.V. Lomivorotov</p>

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