scholarly journals A Rare Case of Extraskeletal Primary Osteosarcoma of Breast: How We Managed

2018 ◽  
Vol 04 (02) ◽  
pp. 077-078
Author(s):  
Kailash Sharma ◽  
Yogendra Singh ◽  
Rajiv Kumar ◽  
Udip Maheshwari ◽  
Sunil Pasricha ◽  
...  
Keyword(s):  
Young People ◽  
Rare Case ◽  
Medical Literature ◽  
Histopathological Examination ◽  
Age Group ◽  
Breast Cancers ◽  
Elderly Age ◽  
Rare Form ◽  
Skeletal Involvement ◽  
Primary Osteosarcoma

AbstractPrimary osteosarcoma arising in breast is a rare form of extra skeletal osteosarcoma, accounting for less than 1% of all breast cancers and 12.5% of sarcomas arising in breast. Fewer than 150 cases of primary osteosarcoma of breast have been reported in the medical literature in the last 50 years. It was reported to have worse outcome compared to typical skeletal osteosarcoma. Osteosarcoma of breast presents in elderly age group unlike skeletal osteosarcoma, which occurs in young people. Diagnosis is by histopathological examination of malignant osteoid and ruling out underlying skeletal involvement.

scholarly journals Thoracic Kidney: Extremely Rare State of Aberrant Kidney

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Mahdi Khoshchehreh ◽  
Omalbanin Paknejad ◽  
Mehrdad Bakhshayesh-Karam ◽  
Marzieh Pazoki
Keyword(s):  
Differential Diagnosis ◽  
Rare Case ◽  
Medical Literature ◽  
Management Options ◽  
Rare Form ◽  
Renal Ectopia ◽  
Diagnosis And Management

The thorax is the rarest place among all forms of renal ectopia. We report a rare case of an unacquired thoracic kidney. Only about 200 cases of the thoracic kidney have ever been reported in medical literature worldwide. In this paper we present the rarest form of nontraumatic nonhernia associated, truly ectopic thoracic kidney. The differential diagnosis and management options and classification of this rare form of aberrant kidney are discussed.

scholarly journals Oncocytoma: a mystifying parotid mass

2019 ◽  
Vol 6 (4) ◽  
pp. 1418
Author(s):  
Jeevan G. Sanjive ◽  
N. S. Reddy ◽  
V. Soundara Rajan
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Pleomorphic Adenoma ◽  
Residual Disease ◽  
Histopathological Examination ◽  
Ct Imaging ◽  
Salivary Gland Tumors ◽  
Age Group ◽  
Elderly Age ◽  
Parotid Swelling

Parotid oncocytoma presents in less than 1% of salivary gland tumors. Therefore, there are only very few reported cases in literature. This tumor is often diagnosed in elderly age group. It is often misdiagnosed clinically as pleomorphic adenoma, hemangioma or Warthin’s tumor. CT imaging usually shows an enhancing lobulated mass; however, it cannot exactly diagnose oncocytoma. It can be confirmed only by histopathological examination. This case report is of an Indian female of 66 years with parotid swelling who underwent total conservative parotidectomy. Post operatively, patient has no residual disease and complications.

scholarly journals A Rare Case of Giant Cell Myocarditis

2020 ◽  
Vol 7 (1) ◽  
pp. 7-10
Author(s):  
Althea C. G. Neblett ◽  
Keyword(s):  
Heart Failure ◽  
Giant Cell ◽  
Rare Case ◽  
Severe Disease ◽  
Disease Process ◽  
Inflammatory Cell Infiltrate ◽  
Age Group ◽  
Older Individuals ◽  
Elderly Age ◽  
Giant Cell Myocarditis

Giant cell myocarditis is a rare condition first described in 1905. It has a reported incidence range from 0.007% to 0.051%. It affects female and male individuals, equally, and usually occurs in young and middle-aged persons. The underlying aetiology of giant cell myocarditis is unknown but it is thought to be mediated by T-lymphocytes. Diagnosis is made via histological examination of myocardial tissue and is characterized by a mixed inflammatory cell infiltrate with multinucleated giant cells and cardiomyocyte necrosis, predominantly affecting the ventricles. The following report describes a rare case of giant cell myocarditis in a 71-yearold man with a history of hypertension and heart failure, who died while waiting to be seen in the emergency department. Autopsy findings revealed an enlarged, dilated heart with histologic features in keeping with giant cell myocarditis, along with features of heart failure. Diagnosis of giant cell myocarditis is less common in the elderly age group, possibly due to a less severe disease process in this age group and it may be misdiagnosed because older individuals may have other cardiovascular diseases (CVDs).

scholarly journals Spectrum of ovarian tumours- a five year study

2017 ◽  
Vol 7 (2) ◽  
pp. 1180-1183
Author(s):  
Sanjeev Narang ◽  
Anjali Singh ◽  
Shrikant Nema ◽  
Rahul Karode
Keyword(s):  
Histopathological Examination ◽  
Age Distribution ◽  
The Elderly ◽  
Surface Epithelium ◽  
Benign Tumors ◽  
Age Group ◽  
Elderly Age ◽  
Hematoxylin And Eosin ◽  
Hematoxylin And Eosin Stain ◽  
Sex Cord Stromal Tumors

Background: Ovarian tumor is the seventh most common cause of cancer related deaths in female. The aim of this study is to find the, morphological and clinicopathological correlation, gross, histological pattern, and incidence of age distribution of ovarian tumors.Materials and Methods: This retrospective and prospective study was carried out from January 2011 to December 2015. The diagnosis was confirmed by histopathological examination using hematoxylin and eosin stain. Special stains and immunohistochemistry were carried out whenever needed.Results: Out of total 158 cases, 62.65% were benign, 3.79% were borderline, and 33.55% were malignant. Histologically, surface epithelial tumors were the most common (74.06%) followed by germ cell tumours(15.82%) and sex cord–stromal tumors (10.12%).Benign tumors were mostly seen in age group of 20–40 years, borderline 21–40 years, and malignant 50–80 years.Conclusion: Tumors originating from surface epithelium are the most common and their malignant counterparts are more frequent in the elderly age group.

Breast carcinoma in young females below the age of 35 years - histopathological and prognostic significance

1970 ◽  
Vol 2 (3) ◽  
pp. 198-202
Author(s):  
D Ghartimagar ◽  
A Ghosh ◽  
OP Talwar ◽  
R Narasimhan
Keyword(s):  
Breast Carcinoma ◽  
Young Women ◽  
Early Stage ◽  
Prognostic Significance ◽  
Age Group ◽  
Breast Cancers ◽  
Young Females ◽  
Younger Age ◽  
Grade 3 ◽  
Group Grade

Background: Breast cancers rarely occur in young women but are known to have more aggressive behaviors and poorer outcome. We here compare the significance of breast carcinoma in female below the age of 35 to the age over 35 whose specimens were submitted to Manipal teaching hospital, Pokhara. Materials and Methods: All cases of mastectomy with carcinoma from January 2000 to September 2011 were included in the study. Clinical and histopathological datas of all cases were reviewed and collated. Results: A total of 148 mastectomy specimens were received, among which, 23 cases (16%) were below 35 years; whereas 125 cases (84%) were above 35 years of age. In both groups, Stage II was the commonest stage but stage III was much more common in older group (33% versus 9%) and stage I was more common in younger age group (39% versus 27%). Bloom Richardson grading showed that in the older age group, grade 1 is the commonest grade (50%) while in the younger group; grade 3 is the commonest (39%). Patients were followed for a varying period of 6 months to 5 years. Two cases (2% of followed up cases) in older group and 3 cases (15% of followed up cases) in the younger group showed recurrence. Conclusion: Breast carcinoma in the patients younger than 35 years though presented at an early stage has higher grade tumor and poorer outcome. DOI: http://dx.doi.org/10.3126/jpn.v2i3.6021 JPN 2012; 2(3): 198-202

A Rare Case: Primary Venous Malformation in Parietal Bone

2021 ◽  
pp. 1-4
Author(s):  
Serhat Yarar ◽  
Ilker Uyar ◽  
Mehmet Emin Cem Yildirim ◽  
Mehmet Dadacı ◽  
Bilsev Ince
Keyword(s):  
Vascular Malformation ◽  
Rare Case ◽  
Histopathological Examination ◽  
Vascular Malformations ◽  
Venous Malformation ◽  
Parietal Bone ◽  
Hair Density ◽  
Trichilemmal Cyst ◽  
Advancement Flaps ◽  
Rotation Advancement

Primary intraosseous vascular malformations (PIVMs) are rare intraosseous lesions, accounting for approximately 0.5–1% of all intraosseous tumours. In this case report, we aimed to present a rare case of intraosseous vascular malformation causing a large lytic area in the parietal bone. A 25-year-old male patient was admitted to the clinic with a mass on the parietal bone. On physical examination, it was observed that the hair density on the mass was decreased, the mass had a soft consistency, and there was no pain on palpation. The patient was operated under local anaesthesia with a provisional diagnosis of a trichilemmal cyst. However, intraoperative diagnosis was a vascular malformation. There was a 3-cm full-thickness defect on the parietal bone caused by the lesion. The mass was excised completely while preserving the integrity of the dura. The resulting defect was reconstructed with bilateral rotation advancement flaps. The calvarial defect was not reconstructed due to equipment inadequacy. No complications were encountered in the postoperative period. Ninety-three PIVM cases have been reported in the skull since 1845. In very few of these cases, the mass is located in the parietal bone. The pathogenesis of PIVMs is not completely understood. The definitive diagnosis is made by histopathological examination. The therapeutic gold standard is surgery. Surgeons should keep in mind that radiological examination before the operation could prevent undesirable complications.

scholarly journals Histopathological Analysis of Endometrial Biopsy in Gandaki Medical College Teaching Hospital, Pokhara, Nepal

2019 ◽  
Vol 12 (1) ◽  
pp. 25-30
Author(s):  
B Parajuli ◽  
G Pun ◽  
S Ranabhat ◽  
S Poudel
Keyword(s):  
Histopathological Examination ◽  
Hydatidiform Mole ◽  
College Teaching ◽  
Histopathological Diagnosis ◽  
Age Group ◽  
Medical College ◽  
Dilatation And Curettage ◽  
Partial Mole ◽  
Proliferative Endometrium ◽  
The Common

Objective: To study the spectrum of histopathological diagnosis of endometrial lesions and their distribution according to age. Methods: All the endometrium samples obtained by the procedure of dilatation and curettage and hysterectomy sent for histopathological examination at Pathology Department of Gandaki Medical College Teaching Hospital, Pokhara, Nepal. The study duration was total 12 months ranging from July 2016 to June 2017. All the endometrial samples were processed, sectioned at 4 - 6 μm and stained with routine H & E stain. Patient’s data including age, sex, procedure of the biopsy taken and histopathological diagnosis were noted. A pathologist, using Olympus microscope, reported the slides. Cases were reviewed by a second pathologist whenever necessary. Results: A total of 128 cases were studied. The most common histopathological diagnosis was proliferative endometrium (28.9%) followed by disorder proliferative endometrium (15.65%). Most of the patients were in age group 36 - 45 years comprising 32.03%. Hydatidiform mole comprised of 7.03% and among Hydatidiform mole, partial mole was more common. Dilatation and curettage (82.8%) was the common procedure in compare to hysterectomy for the evaluation of endometrial lesions. Conclusions: In this study, we observed a variety of endometrial lesions. Most of them are benign; among benign, proliferative endometrium was the common histopathological diagnosis followed by disorder proliferative endometrium. Most common presenting age group was found to be at 36 - 45 years. In evaluation of hydatidiform mole, partial mole was more frequent in compare to complete mole. Conventional dilatation and curettage is the preferred method in developing countries with limited resource to screen endometrial lesion and therefore biopsy should be sent for histopathological examination. Thus histopathological examination of routinely stained hematoxylin and eosin is readily available and widely accepted standard technique for evaluation of the endometrial lesions.

scholarly journals Abnormal Uterine Bleeding in Perimenopausal Age: Different causes and its relation with histopathology

2014 ◽  
Vol 13 (2) ◽  
pp. 135-139 ◽  
Author(s):  
Nazlima Nargis ◽  
Iqbal Karim ◽  
Khondaker Bulbul Sarwar
Keyword(s):  
Histopathological Examination ◽  
Medical Science ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Transvaginal Sonography ◽  
Age Group ◽  
Histopathological Findings ◽  
Medical College ◽  
Gynecology And Obstetrics ◽  
Study Results

Background: Abnormal uterine bleeding (AUB) is the most common reason for gynecological visits for perimenopausal bleeding and may account for more than 25% of all hysterectomies. Objective: This study was aimed to review the causes of abnormal uterine bleeding in perimenopausal women establishing the correlation with ultrasonographic and histopathological examinations. Study Method: This descriptive study was conducted in the department of gynecology and obstetrics, Ibn Sina Medical College, Dhaka during January to December 2012. Two hundred and eleven women were selected for this study, who admitted into the hospital with abnormal uterine bleeding in perimenopausal age. The clinical, ultrasonographic and histopathological findings of these women were evaluated in this study. Results: Menorrhagia was the major symptom (52.6%) irrespective of age and parity. All these women underwent D&C followed by either medical management or hysterectomy depending upon the diagnosis. The histopathological findings of endometrium were analyzed and confirmed as fibroid uterus (58.28%) and DUB (17.58%) correlated well with transvaginal sonography (TVS) and histopathological examination. Hysterectomy conferred other uterine lesions as adenomyosis (18.71%), endometrial polyp (4.81%) and malignancy (1.06%). Conclusion: Abnormal uterine bleeding in perimenopausal age group is a common but ill-defined entity which needs proper evaluation. Accurate diagnosis of the causative factors of AUB in this age group is of utmost importance so that appropriate management can be established early that leads the minimization of the patients’ sufferings. DOI: http://dx.doi.org/10.3329/bjms.v13i2.18295 Bangladesh Journal of Medical Science Vol.13(2) 2014 p.135-139

scholarly journals Hairy Cell Leukemia Presenting with Isolated Skeletal Involvement Successfully Treated by Radiation Therapy and Cladribine: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Ipek Yonal-Hindilerden ◽  
Fehmi Hindilerden ◽  
Sanem Bulut-Dereli ◽  
Eren Yıldız ◽  
Ibrahim Oner Dogan ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Hairy Cell Leukemia ◽  
Histopathological Examination ◽  
Bone Biopsy ◽  
Bone Marrow Involvement ◽  
Bone Lesions ◽  
Hairy Cell ◽  
Cell Leukemia ◽  
Initial Manifestation ◽  
Skeletal Involvement

We describe an unusual case of hairy cell leukemia (HCL) in a 55-year-old male presenting with isolated skeletal disease as the initial manifestation without abnormal peripheral blood counts, bone marrow involvement, or splenomegaly. To the best of our knowledge, there have been only two previous reports of a similar case. The patient presented with pain in the right femur. Anteroposterior radiographs of both femurs revealed mixed lytic-sclerotic lesions. PET scan showed multiple metastatic lesions on axial skeleton, pelvis, and both femurs. Histopathological examination of the bone biopsy revealed an infiltrate of HCL. Localized radiation therapy to both proximal femurs and subsequently 4 weeks later, a 7-day course of 0.1 mg/kg/day cladribine provided complete remission with relief of symptoms and resolution of bone lesions. We addressed the manifestations and management of HCL patients with skeletal involvement.

Sign in / Sign up

Export Citation Format

Share Document