Analysis of Machine Learning Algorithms for Diagnosis of Diffuse Lung Diseases

2018 ◽  
Vol 57 (05/06) ◽  
pp. 272-279 ◽  
Author(s):  
Isadora Cardoso ◽  
Eliana Almeida ◽  
Hector Allende-Cid ◽  
Alejandro Frery ◽  
Rangaraj Rangayyan ◽  
...  

Computational Intelligence Re-meets Medical Image Processing A Comparison of Some Nature-Inspired Optimization Metaheuristics Applied in Biomedical Image Registration Background Diffuse lung diseases (DLDs) are a diverse group of pulmonary disorders, characterized by inflammation of lung tissue, which may lead to permanent loss of the ability to breathe and death. Distinguishing among these diseases is challenging to physicians due their wide variety and unknown causes. Computer-aided diagnosis (CAD) is a useful approach to improve diagnostic accuracy, by combining information provided by experts with Machine Learning (ML) methods. Objectives Exploring the potential of dimensionality reduction combined with ML methods for diagnosis of DLDs; improving the classification accuracy over state-of-the-art methods. Methods A data set composed of 3252 regions of interest (ROIs) was used, from which 28 features were extracted per ROI. We used Principal Component Analysis, Linear Discriminant Analysis, and Stepwise Selection – Forward, Backward, and Forward-Backward to reduce feature dimensionality. The feature subsets obtained were used as input to the following ML methods: Support Vector Machine, Gaussian Mixture Model, k-Nearest Neighbor, and Deep Feedforward Neural Network. We also applied a Deep Convolutional Neural Network directly to the ROIs. Results We achieved the maximum reduction from 28 to 5 dimensions using LDA. The best classification results were obtained by DFNN, with 99.60% of overall accuracy. Conclusions This work contributes to the analysis and selection of features that can efficiently characterize the DLDs studied.

2018 ◽  
Vol 57 (05/06) ◽  
pp. e4-e4
Author(s):  
Isadora Cardoso ◽  
Eliana Almeida ◽  
Hector Allende-Cid ◽  
Alejandro Frery ◽  
Rangaraj Rangayyan ◽  
...  

Author(s):  
S. R. Mani Sekhar ◽  
G. M. Siddesh

Machine learning is one of the important areas in the field of computer science. It helps to provide an optimized solution for the real-world problems by using past knowledge or previous experience data. There are different types of machine learning algorithms present in computer science. This chapter provides the overview of some selected machine learning algorithms such as linear regression, linear discriminant analysis, support vector machine, naive Bayes classifier, neural networks, and decision trees. Each of these methods is illustrated in detail with an example and R code, which in turn assists the reader to generate their own solutions for the given problems.


Geophysics ◽  
2020 ◽  
Vol 85 (4) ◽  
pp. WA41-WA52 ◽  
Author(s):  
Dario Grana ◽  
Leonardo Azevedo ◽  
Mingliang Liu

Among the large variety of mathematical and computational methods for estimating reservoir properties such as facies and petrophysical variables from geophysical data, deep machine-learning algorithms have gained significant popularity for their ability to obtain accurate solutions for geophysical inverse problems in which the physical models are partially unknown. Solutions of classification and inversion problems are generally not unique, and uncertainty quantification studies are required to quantify the uncertainty in the model predictions and determine the precision of the results. Probabilistic methods, such as Monte Carlo approaches, provide a reliable approach for capturing the variability of the set of possible models that match the measured data. Here, we focused on the classification of facies from seismic data and benchmarked the performance of three different algorithms: recurrent neural network, Monte Carlo acceptance/rejection sampling, and Markov chain Monte Carlo. We tested and validated these approaches at the well locations by comparing classification predictions to the reference facies profile. The accuracy of the classification results is defined as the mismatch between the predictions and the log facies profile. Our study found that when the training data set of the neural network is large enough and the prior information about the transition probabilities of the facies in the Monte Carlo approach is not informative, machine-learning methods lead to more accurate solutions; however, the uncertainty of the solution might be underestimated. When some prior knowledge of the facies model is available, for example, from nearby wells, Monte Carlo methods provide solutions with similar accuracy to the neural network and allow a more robust quantification of the uncertainty, of the solution.


2020 ◽  
Vol 19 ◽  
pp. 153303382090982
Author(s):  
Melek Akcay ◽  
Durmus Etiz ◽  
Ozer Celik ◽  
Alaattin Ozen

Background and Aim: Although the prognosis of nasopharyngeal cancer largely depends on a classification based on the tumor-lymph node metastasis staging system, patients at the same stage may have different clinical outcomes. This study aimed to evaluate the survival prognosis of nasopharyngeal cancer using machine learning. Settings and Design: Original, retrospective. Materials and Methods: A total of 72 patients with a diagnosis of nasopharyngeal cancer who received radiotherapy ± chemotherapy were included in the study. The contribution of patient, tumor, and treatment characteristics to the survival prognosis was evaluated by machine learning using the following techniques: logistic regression, artificial neural network, XGBoost, support-vector clustering, random forest, and Gaussian Naive Bayes. Results: In the analysis of the data set, correlation analysis, and binary logistic regression analyses were applied. Of the 18 independent variables, 10 were found to be effective in predicting nasopharyngeal cancer-related mortality: age, weight loss, initial neutrophil/lymphocyte ratio, initial lactate dehydrogenase, initial hemoglobin, radiotherapy duration, tumor diameter, number of concurrent chemotherapy cycles, and T and N stages. Gaussian Naive Bayes was determined as the best algorithm to evaluate the prognosis of machine learning techniques (accuracy rate: 88%, area under the curve score: 0.91, confidence interval: 0.68-1, sensitivity: 75%, specificity: 100%). Conclusion: Many factors affect prognosis in cancer, and machine learning algorithms can be used to determine which factors have a greater effect on survival prognosis, which then allows further research into these factors. In the current study, Gaussian Naive Bayes was identified as the best algorithm for the evaluation of prognosis of nasopharyngeal cancer.


Diagnostics ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 104 ◽  
Author(s):  
Ahmed ◽  
Yigit ◽  
Isik ◽  
Alpkocak

Leukemia is a fatal cancer and has two main types: Acute and chronic. Each type has two more subtypes: Lymphoid and myeloid. Hence, in total, there are four subtypes of leukemia. This study proposes a new approach for diagnosis of all subtypes of leukemia from microscopic blood cell images using convolutional neural networks (CNN), which requires a large training data set. Therefore, we also investigated the effects of data augmentation for an increasing number of training samples synthetically. We used two publicly available leukemia data sources: ALL-IDB and ASH Image Bank. Next, we applied seven different image transformation techniques as data augmentation. We designed a CNN architecture capable of recognizing all subtypes of leukemia. Besides, we also explored other well-known machine learning algorithms such as naive Bayes, support vector machine, k-nearest neighbor, and decision tree. To evaluate our approach, we set up a set of experiments and used 5-fold cross-validation. The results we obtained from experiments showed that our CNN model performance has 88.25% and 81.74% accuracy, in leukemia versus healthy and multiclass classification of all subtypes, respectively. Finally, we also showed that the CNN model has a better performance than other wellknown machine learning algorithms.


2018 ◽  
Vol 8 (8) ◽  
pp. 1280 ◽  
Author(s):  
Yong Kim ◽  
Youngdoo Son ◽  
Wonjoon Kim ◽  
Byungki Jin ◽  
Myung Yun

Sitting on a chair in an awkward posture or sitting for a long period of time is a risk factor for musculoskeletal disorders. A postural habit that has been formed cannot be changed easily. It is important to form a proper postural habit from childhood as the lumbar disease during childhood caused by their improper posture is most likely to recur. Thus, there is a need for a monitoring system that classifies children’s sitting postures. The purpose of this paper is to develop a system for classifying sitting postures for children using machine learning algorithms. The convolutional neural network (CNN) algorithm was used in addition to the conventional algorithms: Naïve Bayes classifier (NB), decision tree (DT), neural network (NN), multinomial logistic regression (MLR), and support vector machine (SVM). To collect data for classifying sitting postures, a sensing cushion was developed by mounting a pressure sensor mat (8 × 8) inside children’s chair seat cushion. Ten children participated, and sensor data was collected by taking a static posture for the five prescribed postures. The accuracy of CNN was found to be the highest as compared with those of the other algorithms. It is expected that the comprehensive posture monitoring system would be established through future research on enhancing the classification algorithm and providing an effective feedback system.


2021 ◽  
Vol 11 ◽  
Author(s):  
Qi Wan ◽  
Jiaxuan Zhou ◽  
Xiaoying Xia ◽  
Jianfeng Hu ◽  
Peng Wang ◽  
...  

ObjectiveTo evaluate the performance of 2D and 3D radiomics features with different machine learning approaches to classify SPLs based on magnetic resonance(MR) T2 weighted imaging (T2WI).Material and MethodsA total of 132 patients with pathologically confirmed SPLs were examined and randomly divided into training (n = 92) and test datasets (n = 40). A total of 1692 3D and 1231 2D radiomics features per patient were extracted. Both radiomics features and clinical data were evaluated. A total of 1260 classification models, comprising 3 normalization methods, 2 dimension reduction algorithms, 3 feature selection methods, and 10 classifiers with 7 different feature numbers (confined to 3–9), were compared. The ten-fold cross-validation on the training dataset was applied to choose the candidate final model. The area under the receiver operating characteristic curve (AUC), precision-recall plot, and Matthews Correlation Coefficient were used to evaluate the performance of machine learning approaches.ResultsThe 3D features were significantly superior to 2D features, showing much more machine learning combinations with AUC greater than 0.7 in both validation and test groups (129 vs. 11). The feature selection method Analysis of Variance(ANOVA), Recursive Feature Elimination(RFE) and the classifier Logistic Regression(LR), Linear Discriminant Analysis(LDA), Support Vector Machine(SVM), Gaussian Process(GP) had relatively better performance. The best performance of 3D radiomics features in the test dataset (AUC = 0.824, AUC-PR = 0.927, MCC = 0.514) was higher than that of 2D features (AUC = 0.740, AUC-PR = 0.846, MCC = 0.404). The joint 3D and 2D features (AUC=0.813, AUC-PR = 0.926, MCC = 0.563) showed similar results as 3D features. Incorporating clinical features with 3D and 2D radiomics features slightly improved the AUC to 0.836 (AUC-PR = 0.918, MCC = 0.620) and 0.780 (AUC-PR = 0.900, MCC = 0.574), respectively.ConclusionsAfter algorithm optimization, 2D feature-based radiomics models yield favorable results in differentiating malignant and benign SPLs, but 3D features are still preferred because of the availability of more machine learning algorithmic combinations with better performance. Feature selection methods ANOVA and RFE, and classifier LR, LDA, SVM and GP are more likely to demonstrate better diagnostic performance for 3D features in the current study.


The prediction of price for a vehicle has been more popular in research area, and it needs predominant effort and information about the experts of this particular field. The number of different attributes is measured and also it has been considerable to predict the result in more reliable and accurate. To find the price of used vehicles a well defined model has been developed with the help of three machine learning techniques such as Artificial Neural Network, Support Vector Machine and Random Forest. These techniques were used not on the individual items but for the whole group of data items. This data group has been taken from some web portal and that same has been used for the prediction. The data must be collected using web scraper that was written in PHP programming language. Distinct machine learning algorithms of varying performances had been compared to get the best result of the given data set. The final prediction model was integrated into Java application


Diabetes is a most common disease that occurs to most of the humans now a day. The predictions for this disease are proposed through machine learning techniques. Through this method the risk factors of this disease are identified and can be prevented from increasing. Early prediction in such disease can be controlled and save human’s life. For the early predictions of this disease we collect data set having 8 attributes diabetic of 200 patients. The patients’ sugar level in the body is tested by the features of patient’s glucose content in the body and according to the age. The main Machine learning algorithms are Support vector machine (SVM), naive bayes (NB), K nearest neighbor (KNN) and Decision Tree (DT). In the exiting the Naive Bayes the accuracy levels are 66% but in the Decision tree the accuracy levels are 70 to 71%. The accuracy levels of the patients are not proper in range. But in XG boost classifiers even after the Naïve Bayes 74 Percentage and in Decision tree the accuracy levels are 89 to 90%. In the proposed system the accuracy ranges are shown properly and this is only used mostly. A dataset of 729 patients can be stored in Mongo DB and in that 129 patients repots are taken for the prediction purpose and the remaining are used for training. The training datasets are used for the prediction purposes.


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