Who’s Programme in Thrombosis and Haemostasis Research

1979 ◽  
Author(s):  
Dr Z. Pisa
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Sudden Death ◽  
Arterial Thrombosis ◽  
Systematic Research ◽  
Present Position ◽  
Limited Success ◽  
Acute Mi ◽  
Special Studies

The Limited success in decreasing the mortality of coronary heart disease (CHD) in general and of sudden death in particular, stresses the needs and importance of systematic research into the etiology and pathogenesis of atherosclerosis and CHD. Prevention seems to be the only effective approach. WHO has included in its CTD long-term programme activities related to these problems. The network of collaborating centres with good epidemiological skills carrying out studies in well-defined populations could provide opportunities for special studies on the role or haemostasis in the etiology and pathogenesis of atherosclerosis and acute MI. In collaboration with ETRO and ISFC methods are being reviewed and sought which are capable of detecting a tendency to arterial thrombosis and atherogenesis. The present position is being discussed.

Serum Homocysteine and Long-Term Risk of Myocardial Infarction and Sudden Death in Patients with Coronary Heart Disease

Cardiology ◽  
2006 ◽  
Vol 107 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Moti Haim ◽  
David Tanne ◽  
Uri Goldbourt ◽  
Ram Doolman ◽  
Valentina Boyko ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Sudden Death ◽  
Serum Homocysteine

The long-term effect of physical activity on incidence of coronary heart disease: A 12-year follow-up study

2005 ◽  
Vol 41 (1) ◽  
pp. 219-225 ◽  
Author(s):  
Kristina Sundquist ◽  
Jan Qvist ◽  
Sven-Erik Johansson ◽  
Jan Sundquist
Keyword(s):  
Physical Activity ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Term Effect ◽  
Follow Up Study ◽  
Long Term Effect

scholarly journals ARTERIAL HYPERTENSION, CORONARY HEART DISEASE AND KIDNEY FUNCTION IN A LONG-TERM OBSERVATION

2020 ◽  
Vol 13 (6) ◽  
pp. 33-37
Author(s):  
OLGA B. OSHCHEPKOVA ◽  
◽  
EVGENY V. ARKHIPOV ◽  
GULNAZ M. MUKHAMETGALIEVA ◽  
OLGA YU. MIKHOPAROVA ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Arterial Hypertension ◽  
Kidney Function ◽  
Long Term Observation

scholarly journals Model for End-Stage Liver Disease Score Predicts the Mortality of Patients with Coronary Heart Disease Who Underwent Percutaneous Coronary Intervention

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
You Chen ◽  
Min Han ◽  
Ying-Ying Zheng ◽  
Feng Zhu ◽  
Aikebai Aisan ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Liver Disease ◽  
Coronary Intervention ◽  
Meld Score ◽  
Bleeding Events ◽  
Percutaneous Coronary ◽  
End Stage ◽  
Long Term Mortality

Background. Coronary heart disease (CHD) is caused by the blockage or spasm of coronary arteries. Evidence shows that liver disease is related to CHD. However, the correlation between the Model for End-Stage Liver Disease (MELD) score and outcomes in patients after percutaneous coronary intervention (PCI) was unclear. Method. A retrospective cohort study involved 5373 patients with coronary heart disease after PCI was conducted from January 2008 to December 2016. Participants were classified to four groups according to the MELD score by quartiles. The primary endpoint was long-term mortality including all-case mortality (ACM) and cardiac mortality (CM). Secondary endpoints included bleeding events, readmission, major adverse cardiovascular events (MACE), major adverse cardiovascular, and cerebrovascular events (MACCE). The longest follow-up time was almost 10 years. Results. There were significant differences in the incidences of ACM ( p = 0.038 ) and CM ( p = 0.027 ) among the four MELD groups, but there was no significant difference in MACEs ( p = 0.496 ), MACCEs ( p = 0.234 ), readmission ( p = 0.684 ), and bleeding events ( p = 0.232 ). After adjusting the age, gender, smoking, drinking status, and diabetes by a multivariable Cox regression analysis, MELD remains independently associated with ACM (HR:1.57, 95%CI 1.052–2.354, p = 0.027 ) and CM (HR:1.434, 95% CI 1.003–2.050, p = 0.048 ). Conclusion. This study indicated that the MELD score had a strong prediction for long-term mortality in CHD patients who underwent PCI.

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