scholarly journals Audiological Abnormalities in Vitiligo Patients: A Hospital-Based Cross-Sectional Study

2019 ◽  
Vol 24 (02) ◽  
pp. e149-e153 ◽  
Author(s):  
Neel Prabha ◽  
Ripudaman Arora ◽  
Namrata Chhabra ◽  
Monalisa Jati ◽  
Nitin M. Nagarkar

Abstract Introduction There are some discrepancies in the literature about the influence of vitiligo on auditory functions. According to some authors, vitiligo influences hearing, whereas others question such influence. Therefore, we conducted a study to evaluate audiological functions in vitiligo patients. Objectives To determine the effect of vitiligo on auditory functions. Methods A hospital-based observational study was done from January 2017 to July 2017. Clinically diagnosed cases of vitiligo were enrolled for the study. A complete otological examination was conducted in all patients. Results Fifty-two patients (male: female 28:24) were included in the study. Ten patients (19.2%) had sensorineural hearing loss (SNHL). Seven patients (13.5%) had bilateral and 3 (5.7%) had unilateral SNHL. High frequency loss was seen in 17 out of 20 ears (10 affected patients), 6 ears had both low and high-frequency hearing loss. Of 12 ears with speech frequency involvement, mild hearing loss was seen in 5 and moderate to severe in 1 ear. Most cases of SNHL were detected in the age group 41 to 60 years old (63.6%), which was statistically significant (p-value 0.00). Conclusion The results of this study suggest that vitiligo patients require routine monitoring for auditory functions for early identification of SNHL. Older subjects with vitiligo might be at a higher risk for audiological abnormalities. These patients should also be informed regarding the associated risk with noise and ototoxic drug exposure.

BMJ Open ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. e027152 ◽  
Author(s):  
Dahui Wang ◽  
Huai Zhang ◽  
Haiyan Ma ◽  
Long Zhang ◽  
Lei Yang ◽  
...  

Hearing loss (≥26 dB threshold in the better ear), as a common chronic condition in humans, is increasingly gaining attention. Relevant research in China is relatively scarce, so we conduct a population-based study to investigate the prevalence of hearing loss among age groups, genders and ears in Zhejiang province, China, from September 2016 to June 2018.Study designPopulation-based cross-sectional studyParticipantsA total of 3754 participants aged 18–98 years and living in Zhejiang province, China.Outcome measuresPure-tone audiometric thresholds were measured at frequencies of 0.125–8 kHz for each subject. All participants were asked to complete a structured questionnaire, in the presence of a healthcare official.ResultsThe prevalence of speech-frequency and high-frequency hearing loss was 27.9% and 42.9%, respectively, in Zhejiang. There were significant differences in auditory thresholds at most frequencies among the age groups, genders (male vs female: 31.6%vs24.1% at speech frequency; 48.9% vs 36.8% at high frequency) and ears. In addition to the common factors affecting both types of hearing loss, a significant correlation was found between personal income and speech-frequency hearing loss (OR=0.69, 95% CI 0.52 to 0.92), and between hyperlipidaemia and high-frequency hearing loss (OR=1.45, 95% CI 1.02 to 2.07).ConclusionThe prevalence of hearing loss was high among people living in Zhejiang, particularly males, and in the left ear. Moreover, hearing thresholds increased with age. Several lifestyle and environment factors, which can be influenced by awareness and education, were significantly associated with hearing loss.


Thorax ◽  
2020 ◽  
Vol 75 (8) ◽  
pp. 632-639 ◽  
Author(s):  
Anitha Vijayasingam ◽  
Emily Frost ◽  
Julie Wilkins ◽  
Lise Gillen ◽  
Presanna Premachandra ◽  
...  

IntroductionIndividuals with chronic lung disease (eg, cystic fibrosis (CF)) often receive antimicrobial therapy including aminoglycosides resulting in ototoxicity. Extended high-frequency audiometry has increased sensitivity for ototoxicity detection, but diagnostic audiometry in a sound-booth is costly, time-consuming and requires a trained audiologist. This cross-sectional study analysed tablet-based audiometry (Shoebox MD) performed by non-audiologists in an outpatient setting, alongside home web-based audiometry (3D Tune-In) to screen for hearing loss in adults with CF.MethodsHearing was analysed in 126 CF adults using validated questionnaires, a web self-hearing test (0.5 to 4 kHz), tablet (0.25 to 12 kHz) and sound-booth audiometry (0.25 to 12 kHz). A threshold of ≥25 dB hearing loss at ≥1 audiometric frequency was considered abnormal. Demographics and mitochondrial DNA sequencing were used to analyse risk factors, and accuracy and usability of hearing tests determined.ResultsPrevalence of hearing loss within any frequency band tested was 48%. Multivariate analysis showed age (OR 1.127; (95% CI: 1.07 to 1.18; p value<0.0001) per year older) and total intravenous antibiotic days over 10 years (OR 1.006; (95% CI: 1.002 to 1.010; p value=0.004) per further intravenous day) were significantly associated with increased risk of hearing loss. Tablet audiometry had good usability, was 93% sensitive, 88% specific with 94% negative predictive value to screen for hearing loss compared with web self-test audiometry and questionnaires which had poor sensitivity (17% and 13%, respectively). Intraclass correlation (ICC) of tablet versus sound-booth audiometry showed high correlation (ICC >0.9) at all frequencies ≥4 kHz.ConclusionsAdults with CF have a high prevalence of drug-related hearing loss and tablet-based audiometry can be a practical, accurate screening tool within integrated ototoxicity monitoring programmes for early detection.


2021 ◽  
Vol 8 ◽  
Author(s):  
Lisa M. H. de Pont ◽  
Josephine M. van Steekelenburg ◽  
Thijs O. Verhagen ◽  
Maartje Houben ◽  
Jelle J. Goeman ◽  
...  

Research Objective: To investigate the correlation between clinical features and MRI-confirmed endolymphatic hydrops (EH) and blood-labyrinth barrier (BLB) impairment.Study Design: Retrospective cross-sectional study.Setting: Vertigo referral center (Haga Teaching Hospital, The Hague, the Netherlands).Methods: We retrospectively analyzed all patients that underwent 4 h-delayed Gd-enhanced 3D FLAIR MRI at our institution from February 2017 to March 2019. Perilymphatic enhancement and the degree of cochlear and vestibular hydrops were assessed. The signal intensity ratio (SIR) was calculated by region of interest analysis. Correlations between MRI findings and clinical features were evaluated.Results: Two hundred and fifteen patients with MRI-proven endolymphatic hydrops (EH) were included (179 unilateral, 36 bilateral) with a mean age of 55.9 yrs and median disease duration of 4.3 yrs. Hydrops grade is significantly correlated with disease duration (P &lt; 0.001), the severity of low- and high-frequency hearing loss (both P &lt; 0.001), and the incidence of drop attacks (P = 0.001). Visually increased perilymphatic enhancement was present in 157 (87.7%) subjects with unilateral EH. SIR increases in correlation with hydrops grade (P &lt; 0.001), but is not significantly correlated with the low or high Fletcher index (P = 0.344 and P = 0.178 respectively). No significant differences were found between the degree of EH or BLB impairment and vertigo, tinnitus or aural fullness.Conclusion: The degree of EH positively correlates with disease duration, hearing loss and the incidence of drop attacks. The BLB is impaired in association with EH grade, but without clear contribution to the severity of audiovestibular symptoms.


2020 ◽  
Vol 7 (2) ◽  
pp. 47-57
Author(s):  
Refad A. Azeez

Age related hearing loss is one of the most common chronic health conditions affecting the elderly people. With aging, risk of Presbycusis and hyperlipidemia increases. Although most studies do reach some sort of agreement, the evidence supporting a relationship between presbycusis and hyperlipidemia remains questionable. The objective of this study is to determine the association between age related hearing loss and hyperlipidemia and assess the severity of hearing loss in hyperlipidemic patients. This cross sectional analytic study was carried out at ENT Out Patient Clinic at Al Sader teaching Hospital from March 2019 to December 2019. A cross‑sectional study on 52 patients with Hyperlipidemia and 42 non Hyperlipidemic patients was carried out during March 2019 to December 2019. All patients were evaluated for hearing loss by subjecting to pure tone audiometry, blood investigations were done in form of lipid profile, blood sugars, thyroid function test, blood urea and serum creatinine levels. Group A consisted of 22 (42.3%) males and 30 (57.7%) female while group B consisted of 23 (54.8%) male and 19 (45.2%) female individuals. Audiological assessment by PTA was show that the prevalence of presbycusis among hyperlipidemic group more than non hyperlipidemic with significant statistical difference (P value <0.05). Prevalence was 76.9%. In conclusion; there is statistically significant association between presbycusis and hyperlipidemia especially those with hyercholestrolemia.


AAOHN Journal ◽  
1998 ◽  
Vol 46 (2) ◽  
pp. 67-75 ◽  
Author(s):  
Oi Saeng Hong ◽  
Shu-Pi C. Chen ◽  
Karen M. Conrad

The purposes of this study of airport workers were to a) determine the prevalence and symptoms of hearing loss, and b) identify compliance in using hearing protective devices (HPDs) and its relationship with hearing loss. This cross sectional epidemiological study was conducted with 255 noise exposed and 195 non-noise exposed, full time, male workers at a large metropolitan airport in Seoul, Korea. The three measures used were the self administered Occupational Hearing Questionnaire (OHQ), an audiological assessment, and a record review of baseline hearing and noise levels of locations in which the employee worked. The results showed a significant difference in prevalence of hearing loss (more than 25dB) between the noise and the non-noise exposed groups ( p < .05). About 60.8% of noise exposed workers reported continuous use of the HPDs. The continuous HPD users had significantly lower rates of hearing loss than the occasional users or non-users. The major symptom for workers with low frequency hearing loss was trouble in communication, whereas tinnitus and fullness in the ear were the most common symptoms for the workers with high frequency hearing loss. The airport workers exposed to excessive noise had a great deal of high frequency hearing loss. The degree of hearing loss present reinforces the need for aggressive hearing conservation programs among airport workers exposed to noise.


2021 ◽  
Vol 71 (Suppl-3) ◽  
pp. S607-11
Author(s):  
Muhammad Javid Iqbal Pattafi ◽  
Nazia Mumtaz ◽  
Ghulam Saqulain

Objective: To determine the frequency and risk factors of occupational noise induced hearing loss. Study Design: Cross sectional study. Place and Duration of Study: Dispensary Unit of Jaith Bhuta Sugar Mill near Rahim Yar Khan, Southern Punjab.from Aug 2017 to Jan 2018. Methodology: This study was conducted using nonprobability consecutive sampling. n=300 workers of bothgenders aged 18-40 years were assessed. Basic demographic parameters, otoscopic examination and Pure Tone Audiometry were used for data collection. The Data was analyzed by using SPSS version 21. Results: Study included 215 (71.7%) males and 85 (28.3%) females with male to female ratio of 2.53: 1 and meanage of 28.34 ± 4.61 years. The frequency rate of hearing impairment (HI) was 90 (30%) out of 300 respondents inthis study. Out of 70 (100%) of respondents were affected with duration of job of 6-10 years. There was significant association between gender, age, education, duration of noise exposure with occupational noise induced hearing loss with p-value <0.001. Conclusion: There was high frequency of occupational noise induced hearing loss (ONIHL) with significantrisk factors being level and duration of exposure to noise (ETN), age, gender, education and hearing protectivedevices (HPD)’s.


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