Low Birth Weight and Prematurity Are Associated with Hypertensive Disorder of Pregnancy in Later Life: A Cross-Sectional Study in Japan

2020 ◽  
Author(s):  
Takumi Kurabayashi ◽  
Hideki Mizunuma ◽  
Toshiro Kubota ◽  
Kazue Nagai ◽  
Kunihiko Hayashi
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Later Life ◽  
Health Study ◽  
Baseline Survey ◽  
Hypertensive Disorder ◽  
Cross Sectional ◽  
History Of ◽  
Hypertensive Disorder Of Pregnancy

Abstract Objective We previously reported that hypertensive disorder of pregnancy (HDP) was a risk factor for hypertension and hypercholesterolemia in later life. Additionally, the age-adjusted odds ratio (OR) of HDP was 2.72 for Japanese women whose mothers had a history of HDP versus those whose mothers did not. This study aimed to clarify the association of HDP with birth weight and gestational age. Study Design A self-administered baseline survey of the Japanese Nurses' Health Study (JNHS) cohort was conducted from 2001 to 2007. Data on 17,278 parous female nurses who knew their own birth weights were extracted from the JNHS baseline survey (n = 49,927) and subjected to cross-sectional, retrospective analysis. Data on weeks of gestation, birth weight, and history of HDP were collected. Results The age-adjusted ORs for HDP were 1.62 (95% confidence interval [CI]: 1.20–2.19) for birth weight <2,000 g, 1.24 (CI: 1.04–1.48) for 2,000 to 2,499 g, 1.11 (CI: 1.00–1.23) for 2,500 to 2,999 g, and 1.08 (CI: 0.94–1.24) for ≥3,500 g compared with 3,000 to 3,499 g. The age-adjusted ORs for HDP were 1.27 (95% CI: 1.04–1.54) for a gestational age < 37 weeks and 0.93 (0.70–1.23) for ≥42 weeks compared with 37–41 weeks. The age-adjusted OR of the birth weight score for HDP in later life was 0.98 (CI: 0.94–1.03; Cochran–Armitage trend test: z = 0.401, p = 0.688). Conclusion Among women in Japan, a history of low birth weight and prematurity are risk factors for HDP in later life. The risk of HDP among women born with low birth weight and/or premature deserves attention.

scholarly journals Immediate outcome of neonates with maternal hypertensive disorder of pregnancy at a neonatal intensive care unit

2015 ◽  
Vol 6 (2) ◽  
pp. 57-60 ◽  
Author(s):  
Mahmuda Hassan ◽  
Marium Begum ◽  
SM Zabrul Haque ◽  
Nasim Jahan ◽  
BH Nazma Yasmeen ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Hospital Stay ◽  
Gestational Age ◽  
Gestational Hypertension ◽  
Chronic Hypertension ◽  
Hypertensive Disorder ◽  
Average Hospital ◽  
Female Ratio ◽  
Hypertensive Disorder Of Pregnancy

Aims : Hypertensive disorders in pregnancy remain a major cause of maternal and neonatal morbidity and mortality worldwide. This study prospectively examined the immediate neonatal outcome of women with maternal hypertensive disorder of pregnancy( HDP).Methods : Sixty mothers and their newborn were selected. Mothers with gestational hypertension, preeclampsia, preeclampsia superimposed on chronic hypertension and chronic hypertension were included.Results : Forty five (75%) mothers were mutipara and 15(25%) were primipara. Mean maternal age was 26.4 years. Mean gestational age was 34+4 weeks. 38 were male and 22 were female with Male: Female ratio was 1.72: 1. Thirty six (60%) were from in patient with regular antenatal check up, 60% mothers had gestational hypertension. Fifty four (90%) mothers needed lower uterine caesarian section. Forty four (73.33%) delivered preterm before 36 weeks of pregnancy. Low birth weight (<2.5kg) babies were 30(50%), very low birth weight (<1.5kg) were 16(26.66%). Intrauterine growth retardation (IUGR) were 18(30%) and Appropriate for gestational age( AGA) were 14(23.33%). Respiratory distress 30(50%) were the most common cause of admission, other associated problems were perinatal asphyxia (PNA) with seizure and meconium aspiration syndrome and to rule out sepsis in suspected cases. Nine (15%) needed ventilator care and 6(10%) needed nasal continuous positive airway pressure (NCPAP) for respiratory problem. 6(10%) babies were expired and 54(90%) survived. Average hospital stay were 18.32(±10.68) days with a highest hospital stay of 49 days and the lowest 4 days.Conclusion : Maternal hypertensive disorder of pregnancy is associated with neonatal morbidity.Northern International Medical College Journal Vol.6(2) 2015: 57-60

scholarly journals The Prevalence of Necrotizing Enterocolitis and Associated Factors Among Enteral Fed Preterm and Low Birth Weight Neonates Admitted in Selected Public Hospitals in Addis Ababa, Ethiopia: A Cross-sectional Study

2021 ◽  
Vol 8 ◽  
pp. 2333794X2110196
Author(s):  
Sitotaw Molla Mekonnen ◽  
Daniel Mengistu Bekele ◽  
Fikrtemariam Abebe Fenta ◽  
Addisu Dabi Wake
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Necrotizing Enterocolitis ◽  
Gestational Age ◽  
Associated Factors ◽  
Addis Ababa ◽  
Cross Sectional Study ◽  
Public Hospitals ◽  
Sectional Study ◽  
Cross Sectional

Necrotizing enterocolitis (NEC) remains to be the most critical and frequent gastrointestinal disorder understood in neonatal intensive care units (NICU). The presented study was intended to assess the prevalence of NEC and associated factors among enteral Fed preterm and low birth weight neonates. Institution based retrospective cross-sectional study was conducted on 350 enteral Fed preterm and low birth weight neonates who were admitted at selected public hospitals of Addis Ababa from March 25/2020 to May 10/2020. The data were collected through neonates’ medical record chart review. A total of 350 participants were enrolled in to the study with the response rate of 99.43%. One hundred eighty-four (52.6%) of them were male. The majority 123 (35.1%) of them were (32 + 1 to 34) weeks gestational age. The prevalence of NEC was (25.4%) (n = 89, [95% CI; 21.1, 30.0]). Being ≤28 weeks gestational age (AOR = 3.94, 95% CI [2.67, 9.97]), being (28 + 1 to 32 weeks) gestational age (AOR = 3.65, 95% CI [2.21, 8.31]), birth weight of 1000 to 1499 g (AOR = 2.29, 95% CI [1.22, 4.33]), APGAR score ≤3 (AOR = 2.34, 95% CI [1.32, 4.16]), prolonged labor (AOR = 2.21, 95% CI [1.35, 6.38]), maternal chronic disease particularly hypertension (AOR = 3.2, 95% CI [1.70, 5.90]), chorioamnionitis (AOR = 4.8, 95% CI [3.9, 13]), failure to breath/resuscitated (AOR = 2.1, 95% CI [1.7, 4.4]), CPAP ventilation (AOR = 3.7, 95% CI [1.50, 12.70]), mixed milk (AOR = 3.58, 95% CI [2.16, 9.32]) were factors significantly associated with NEC. Finally, the prevalence of NEC in the study area was high. So that, initiating the programs that could minimize this problem is required to avoid the substantial morbidity and mortality associated with NEC.

scholarly journals PERINATAL OUTCOME IN BABIES IN RELATION TO SEVERITY OF MATERNAL HYPERTENSION

2020 ◽  
Vol 4 (12) ◽  
Author(s):  
Jewel Maria George ◽  
Thomas Antony
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Perinatal Outcome ◽  
Neonatal Resuscitation ◽  
Categorical Variables ◽  
Hypertensive Disorder ◽  
Mortality Pattern ◽  
Male Predominance ◽  
Maternal Hypertension ◽  
Hypertensive Disorder Of Pregnancy

Background and objectives: Hypertensive disorder of pregnancy is a major cause of   maternal and neonatal mortality and morbidity worldwide. This study prospectively examined the immediate neonatal outcome of women with hypertensive disorder of pregnancy .Objectives were to study the effects of maternal hypertension on   APGAR score at birth and the need for neonatal resuscitation  as well as  to study neonatal morbidity profile and mortality pattern. Methods: Observational study was conducted on 125 babies born to mothers with hypertension in the neonatal intensive care unit of jubilee mission medical college. To study the effects of maternal hypertension and perinatal outcome, frequency and percentages were applied. Following parameters like prematurity, IUGR, low birth weight, hypoglycemia, hypocalcemia, hyperbilirubinemia will be studied .Chi square test will be applied for categorical variables and independent two sample t test will be applied for numerical variables. Results: Study population had male predominance.60% underwent LSCS.SGA babies maximum with eclampsia(45.5%),IUGR babies maximum with pre-eclampsia(9.4%).Prematurity seen in all babies born to eclamptic and 40.6% born to pre-eclamptic mothers(p-0.001).1 and 5minute APGAR were<7 in 15.9%,15.6%,18.2% and 12.2%,9.4%,9.1% of babies born to mothers with PIH, pre-eclampsia and eclampsia respectively. Other variables not statistically significant. Death was maximum in babies born to pre-eclamptic mothers (9.4 %). Conclusions: Maternal hypertension was associated with higher risk of adverse perinatal outcomes; necessitating need to strengthen prevention, early diagnosis and management of pregnancy-induced hypertension. Keywords: APGAR; prematurity; low birth weight; hypoglycemia; hyperbilirubinemia; hypocalcemia; respiratory distress  

scholarly journals LOW BIRTH WEIGHT BABIES;

2017 ◽  
Vol 24 (08) ◽  
pp. 1176-1180
Author(s):  
Brig® Khalid Mehmood ◽  
Ijaz Ali ◽  
Syed Hyder Raza
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Data Collection Tool ◽  
Cross Sectional ◽  
Normal Birth ◽  
Low Birth Weight Babies ◽  
Study Setting

Objectives: To determine the proportion of LBW Babies among those deliveredat DHQ Hospital Mirpur. Study design: Descriptive cross sectional study. Setting: DHQ hospitalMirpur AJK. Duration of study: January 2013-May 2013. Sample size: 459 deliveries. Studypopulation: women reporting in Peads OPD of DHQ hospital Mirpur AJ&K with their babiesduring study period. Sampling technique: Convenience method. Data collection tool: Datacollection Performa. Data analysis: SPSS version 14.0.Results: Out of 459 deliveriesconducted at Divisional Head Quarter hospital Mirpur, 149 cases of low birth weight babies(<2500gms) whereas the rest 310 had normal birth weight. Frequency of Low Birth Weight inmale new born babies was high, i.e ratio of male babies were 55% (82) out of 149 individualswhile females were 45% (67). Less than 37 weeks of gestational age, 37% (55) were pretermbabies and 37 – 42 weeks of gestational age, 63% (94) were full term babies.

Pre-discharge growth pattern of very low birth weight infants (VLBW): A 5 year single center experience

2020 ◽  
pp. 1-6
Author(s):  
S.H. Elbeely ◽  
M.A. AlQurashi
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Growth Pattern ◽  
Very Low Birth Weight ◽  
Single Center ◽  
Low Birth Weight Infants ◽  
Cross Sectional ◽  
Vlbw Infants ◽  
The Mean

BACKGROUND: Very low birth weight infants born prematurely are at greater risk for growth delays that lead to Ex-utero Growth Restriction (EUGR) during vulnerable periods of organ structural and functional development. There is considerable evidence that early growth failure has adverse effects on long term neurodevelopment in children which often persists into adulthood. METHODS: This is a single-center cross-sectional study on live newborn infants with birth weight ranges from 500 to 1500 grams (VLBW) and gestational age (GA) between 24–32 weeks who were admitted to NICU at KAMC-Jeddah over a 5 year period (2009–2013). This study aims to evaluate predischarge growth pattern of VLBW infants in terms of weight, head circumference (HC) and length and to identify important variables that have influenced such growth pattern. RESULTS: Of the 135 infants included in the final analysis, 68 (50.4%) were male and 67 (49.6%) were female and the mean gestational age was 28.83±2.064 weeks and the mean birth weight 1166.74±256 grams. Ninety-two infants (68%) had discharge weight at ≤10th percentile and forty four (32%) had their weight >10th percentile. HC was the lowest affected among the anthropometric measurements with 42% ≤10th percentile. In terms of linear growth, 62% had their length ≤10th percentile. Amongst infants born ≤750 grams, 71% and 70% had HC and height at ≤10th percentile respectively, at the time of discharge. BPD was significantly associated with EUGR (p = 0.026). CONCLUSIONS: This study demonstrates that almost 2/3rd of VLBW infants born at KAMC-Jeddah with birth weight ≤750 grams were discharged home with EUGR as demonstrated by their weight, length, and HC ≤10th percentile. BPD was found to be significantly associated with EUGR amongst post-natal factors influencing EUGR.

scholarly journals The prevalence of underweight in children aged 5 years and younger attending primary health care clinics in the Mangaung area, Free State

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Danae Koetaan ◽  
Andrea Smith ◽  
Anke Liebenberg ◽  
Marietjie Brits ◽  
Christos Halkas ◽  
...  
Keyword(s):  
Health Care ◽  
Primary Health Care ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Free State ◽  
Health Clinic ◽  
Cross Sectional ◽  
Health Care Clinics ◽  
Primary Health ◽  
History Of

Background: The Constitution of South Africa stipulates that all children have the right to basic nutrition; however, a great number of South African children are underweight for age. It is important to address malnutrition as it is associated with more than 50% of all child deathsin developing countries and also increases the risk for infective diseases.Aim: To determine the prevalence of underweight in children aged 5 years and younger attending primary health care clinics in the Mangaung area, Free State, and determine the possible underlying causes thereof.Setting: Six preselected primary health care clinics in the Mangaung area.Methods: This was a cross-sectional study. Demographic and clinical information and anthropometric measurements were collected from the children’s Road-to-Health clinic cards,obtained from the children’s caregivers.Results: In total, 240 children were included, of which 51.7% were girls. The median age was 7.5 months. The weight-for-age graph revealed that 7.7% (95% confidence interval: 4.8%;11.9%) of children were underweight or severely underweight for age. Length-for-age and weight-for-height graphs were mostly incomplete. Underweight children differed from normal weight children regarding birth weight (low birth weight 70.6% vs. 12.4%) and history of malnutrition (60.0% vs. 7.1%).Conclusion: The prevalence of underweight in children aged 0–5 years attending primary health care clinics in Mangaung is 7.7% based on information available from Road-to-Healthcards. This figure could be higher if these cards were filled in more accurately. A low birth weight and history of malnutrition are associated with underweight.

scholarly journals Birth weight and psychological distress at age 45–51 years

2005 ◽  
Vol 187 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Nicola J. Wiles ◽  
Tim J. Peters ◽  
David A. Leon ◽  
Glyn Lewis
Keyword(s):  
Psychological Distress ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Direct Effect ◽  
Gestational Age ◽  
Affective Disorders ◽  
Later Life ◽  
Adult Mental Health ◽  
Early Life Factors ◽  
Childhood Factors

BackgroundIt is unclear whether the effect of low birth weight on common affective disorders in later life is director mediated through childhood factors.AimsTo determine whether birth weight has a direct effect on psychological distress in adulthood not mediated by childhood IQ or behavioural problems.MethodParticipants (n=5572) of the Aberdeen Children of the 1950s study had data on birth weight for gestational age and adult psychological distress. Logistic regression was used to examine the association between these factors, with adjustment for confounders and potential childhood mediators.ResultsChildren born full term but weighing less than 5.5 lb had increased odds of psychological distress in later life after adjustment for potential confounders (OR=1.49, 95% CI 1.01–2.20). Further adjustment for childhood IQ and behaviour did not attenuate the association. A 1 s.d. decrease in birth weight for gestational age was associated with a 4% increased odds of psychological distress in adulthood (OR=1.04, 95% CI 0.97–1.12).ConclusionsLow birth weight for gestational age, particularly atterm, was associated with adult psychological distress. This was not mediated by childhood factors, suggesting a direct effect of early life factors on adult mental health. A neurodevelopmental pathway may therefore be implicated.

scholarly journals A STUDY ON VERY LOW BIRTH WEIGHT BABIES ADMITTED IN NICU

2020 ◽  
pp. 1-3
Author(s):  
Janki Prajapati ◽  
Sucheta Munshi ◽  
Ankit Chauhan
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Very Low Birth Weight ◽  
Perinatal Care ◽  
Morbidity And Mortality ◽  
Mortality Pattern ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
Major Factors

Background: Very low birth weight (VLBW) neonates are at high risk for morbidity and mortality. Preterm birth is one of the major clinical problems in Obstetrics and Neonatology. Aim & Objective: To study morbidity and mortality pattern of VLBW neonates admitted to NICU at Department of Pediatrics, Civil hospital, Ahmedabad. Methodology: This cross-sectional prospective observational study was performed on all hospitalized VLBW neonates. Their course during hospitalization and relevant was documented in pre designed performa. Results: In the present study, out of 1748 neonates, 374 (21.39%) were VLBW with 69% males. Mean gestational age was 31.3±1.8 weeks; mean birth weight 1279±193 grams. Common morbidities in VLBW neonates are Neonatal jaundice, Probable sepsis, Apnea of prematurity and RDS. Mortality rate is improved with increasing gestational age and weight. Conclusion: Birth weight and mechanical ventilation are the 2 major factors responsible for mortality. A decline in the mortality and morbidity of these newborns (especially the ELBW neonates) can only be made possible through optimizing perinatal care including regionalization, CPR at birth, early NCPAP and quality improved collaborative (QIC) in our NICU.

scholarly journals Prevalence and risk factors associated with low birth weight babies-a cross sectional study

2021 ◽  
Vol 8 (7) ◽  
pp. 1168
Author(s):  
Gurunathan Gopal
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Maternal Risk ◽  
Factors Associated ◽  
The World

Background: Babies with a birth weight of less than 2500 grams, irrespective of the period of their gestation are termed as low birth weight (LBW) babies. Despite consistent efforts to improve the quality of maternal and child health, more than twenty million LBW babies are born every year throughout the world. The present study was to explore the effects of various maternal risk factors associated with low birth-weight of institutionally delivered newborns. Across the world, neonatal mortality is 20 times more likely for LBW babies compared to normal birth weight (NBW) babies (>2.5 kg).Methods: A cross sectional study was conducted in neonatal intensive care unit (NICU) of ACS Medical College and Hospital, Chennai from December 2019 to October 2020. Altogether 350 babies were taken who were delivered at ACS hospital.Results: The number of times of ANC attendance was also significantly associated with LBW, odds ratio (OR)=1.296, and p=0.001. The number of meals was not associated with LBW OR=0.946, and p=0.831. The gestational age assessed as completed weeks of pregnancy was significantly associated with LBW OR=3.302; p=0.00001.Conclusions: This study suggests that there are several factors interplaying which lead to LBW babies. Socio-demographic factors (maternal age and gestational age) and antenatal care are more important.

scholarly journals Hypertensive disorder of pregnancy and its immediate outcome on neonates in a tertiary care hospital of Western Nepal

2019 ◽  
Vol 8 (6) ◽  
pp. 1343
Author(s):  
Badri Kumar Gupta ◽  
Amit Kumar Shrivastava ◽  
Laxmi Shrestha
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Tertiary Care ◽  
Morbidity And Mortality ◽  
Chronic Hypertension ◽  
Hypertensive Disorder ◽  
Care Hospital ◽  
Early Management ◽  
Female Ratio ◽  
Hypertensive Disorder Of Pregnancy

Background: Hypertensive disorders in pregnancy remain a major cause of maternal and neonatal morbidity and mortality worldwide. This study prospectively examined the immediate neonatal outcome of women with maternal hypertensive disorder of pregnancy (HPD).Methods: This is a prospective study conducted at NICU in Universal College of Medical Sciences Hospital over a period from 2nd February 2018 to 1st February 2019. Fifty-two mothers and their newborn were selected. Mothers with gestational hypertension, preeclampsia, and preeclampsia superimposed on chronic hypertension and chronic hypertension were included.Results: Mean maternal age was 26.4 years. Mean gestational age was 34±4 weeks. 38 were male and 24 were female with male: female ratio 1.72:1. Thirty seven (71.2%) mothers needed lower uterine caesarian section, fourteen (26.9%) mothers delivered NVD and one (1.9%) forceps delivery. Low birth weight (<2.5kg) babies were 25 (48.1%%), very low birth weight (<1.5kg) were 9 (17.3%) and normal weight were 18 (34.3%). Intrauterine growth retardation (IUGR) were 18(30%). Perinatal asphyxia 10 (19.2%) were most common cause of admission, other cause of admission were sepsis and prematurity.Conclusions: Eclampsia is still a common and serious complication of pregnancy. Proper antenatal care, detection of preeclampsia with early management and timely referral of high risk patient, administered of MgSO4 in correct doses and properly timed caesarean section in selected cases would reduce the incidence of eclampsia associated maternal and perinatal morbidity and mortality in our facility.

Sign in / Sign up

Export Citation Format

Share Document