scholarly journals Current Concepts on the Pathogenesis of Peri-implantitis: A Narrative Review

2021 ◽  
Author(s):  
Ioannis Fragkioudakis ◽  
Georgia Tseleki ◽  
Aikaterini-Elisavet Doufexi ◽  
Dimitra Sakellari
Keyword(s):  
Periodontal Diseases ◽  
Foreign Body Response ◽  
Narrative Review ◽  
Metal Particles ◽  
Gram Negative Bacteria ◽  
Dental Practice ◽  
Implant Treatment ◽  
Specific Line ◽  
Body Response

AbstractAs implant treatment has been integrated in contemporary dental practice, complications with the forms of peri-implant mucositis and peri-implantitis have also increased in prevalence. Peri-implantitis is the more severe biological complication and is defined as an inflammatory disease affecting peri-implant tissues resulting in bone and eventually implant loss. In addition, the treatment of peri-implantitis has currently become a substantial global economic burden. In the current study, a search was conducted in several electronic databases using specific keywords relevant to the article’s main topic. An increasing number of scientific reports have investigated the etiopathology of peri-implant diseases, focusing mainly on peri-implantitis. Microbial biofilm consists an important etiological factor of peri-implant pathology analogous to periodontal diseases. Although several data confirm that peri-implant infections are dominated by gram-negative bacteria, similar to periodontal infections, there is evidence that some cases may harbor a distinct microbiota, including opportunistic microorganisms and/or uncultivable species. Additionally, data support that several parameters, such as genetic predisposition of individual patients, occlusal overload, and local factors such as titanium particles and excess cement, may be implicated in peri-implantitis pathogenesis. Simultaneously, the release of titanium metal particles and their biological consequences or the presence of excess cement in the adjacent peri-implant tissues have also been suggested as factors that contribute to peri-implant pathology. A specific line of research also indicates the role of foreign body response to implant installation. This narrative review aims to discuss the current concepts of etiopathogenetic factors implicated in peri-implantitis.

scholarly journals The Role of Exercise in Adaptation and Body Response to Doxorubicin-Induced Cellular Toxicity: A Narrative Review Study

2020 ◽  
Vol 19 (8) ◽  
pp. 869-888
Author(s):  
S. Z. Hashemi Chashemi ◽  
S. S. Hojati ◽  
V. Dabidiroshan ◽  
kh. Jalali Dehkordi ◽  
◽  
...  
Keyword(s):  
Narrative Review ◽  
Cellular Toxicity ◽  
Review Study ◽  
Body Response

scholarly journals Dental morbidity in Russia

2020 ◽  
Vol 101 (5) ◽  
pp. 713-718
Author(s):  
A K Salakhov ◽  
S S Ksembaev ◽  
R F Baykeev ◽  
E M Silagadze
Keyword(s):  
Periodontal Diseases ◽  
Epidemiological Studies ◽  
High Rate ◽  
Dental Practice ◽  
Dental Anomalies ◽  
Preventive Program ◽  
High Prevalence ◽  
Preventive Work ◽  
Dental Diseases

At present, the most common dental diseases in most regions of Russia are caries, periodontal diseases, and dentofacial anomalies. A literature review was carried out on the prevalence of major dental diseases in Russian adult. The study aimed to analyze the literature on dental morbidity in Russia in the following areas: assessment of the prevalence, intensity, and treatment need of major dental diseases, depending on regional particularities, age, and sex differences. Caries and periodontal diseases are a major medical and social problem. The results of recent epidemiological studies have shown that almost the entire Russian adult has signs of these diseases. There is also a high rate of dental anomalies in children. The high prevalence of dental diseases indicates the need to strengthen the role of preventive work in the doctor's work. In conducting prevention program, it is important to consider the prevalence and intensity of major dental diseases which have pronounced regional particularities. Dental practice in recent years has shown that as a result of a targeted and effective preventive program, you can significantly reduce the level of dental morbidity.

scholarly journals Role of plasma fibronectin in the foreign body response to biomaterials

Biomaterials ◽  
2007 ◽  
Vol 28 (25) ◽  
pp. 3626-3631 ◽  
Author(s):  
Benjamin G. Keselowsky ◽  
Amanda W. Bridges ◽  
Kellie L. Burns ◽  
Ciara C. Tate ◽  
Julia E. Babensee ◽  
...  
Keyword(s):  
Foreign Body ◽  
Foreign Body Response ◽  
Plasma Fibronectin ◽  
Body Response

Role of TRPV4 mechanosensing in foreign body response and giant cell formation

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Shaik O. Rahaman ◽  
Rakesh K. Arya ◽  
Rishov Goswami
Keyword(s):  
Foreign Body ◽  
Giant Cell ◽  
Cell Formation ◽  
Foreign Body Response ◽  
Giant Cell Formation ◽  
Body Response

Mechanisms of Granulomatous Lung Disease from Inhaled Beryllium: The Role of Antigenicity in Granuloma Formation

1991 ◽  
Vol 19 (4_part_1) ◽  
pp. 514-525 ◽  
Author(s):  
Patrick J. Haley
Keyword(s):  
Foreign Body ◽  
Lung Disease ◽  
Molecular Mechanisms ◽  
Foreign Body Response ◽  
Immune Mediated ◽  
Granulomatous Lung Disease ◽  
Foreign Body Reactions ◽  
Similar Disease ◽  
Body Response

Granulomatous lung disease is a debilitating and sometimes fatal condition encountered in humans, for which the cellular and molecular mechanisms are poorly understood. Two patterns of granulomatous lung disease are recognized; foreign-body reactions and immune-mediated granulomas. Beryllium inhalation by humans results, in a small number of exposed individuals, in a chronic, granulomatous, immune-mediated pulmonary disease (chronic beryllium lung disease, CBD). Animal models used to study CBD have demonstrated significant species differences in the pathologic response to beryllium. While rats exposed to beryllium appear to develop a chronic, foreign-body response within the lung, dogs so exposed develop beryllium-specific immune responses within the lung and blood, accompanied by immune granulomas within the lung. At the heart of this difference appears to be the ability of the dog, but not the rat, to immunologically recognize the antigenicity of beryllium. This important difference further underscores the need to understand the mechanistic differences among similar disease syndromes, particularly if therapeutic regimens are to be used.

scholarly journals Interleukin-1 Receptor Type I Gene-Deficient Mice Are Less Susceptible to Staphylococcus epidermidisBiomaterial-Associated Infection than Are Wild-Type Mice

2000 ◽  
Vol 68 (12) ◽  
pp. 6924-6931 ◽  
Author(s):  
Jaap Jan Boelens ◽  
Tom van der Poll ◽  
Sebastian A. J. Zaat ◽  
Jean L. A. N. Murk ◽  
Jan J. Weening ◽  
...  
Keyword(s):  
Interleukin 1 ◽  
Cell Formation ◽  
Foreign Body Response ◽  
Receptor Type ◽  
Type I ◽  
Wild Type ◽  
Sterile Saline ◽  
Giant Cell Formation ◽  
Body Response

ABSTRACT Elevated concentrations of interleukin-1 (IL-1) were found in tissue surrounding biomaterials infected with Staphylococcus epidermidis. To determine the role of IL-1 in biomaterial-associated infection (BAI), IL-1 receptor type I-deficient (IL-1R−/−) and wild-type mice received subcutaneous implants of silicon elastomer (SE) or polyvinylpyrrolidone-grafted SE (SEpvp), combined with an injection of 106 CFU of S. epidermidis or sterile saline. Neither mouse strain was susceptible to BAI around SE. IL-1R−/− mice with SEpvp implants had a no abscess formation and a reduced susceptibility to persistent S. epidermidis infection. The normal foreign body response, characterized by giant-cell formation and encapsulation, was delayed around SEpvp in wild-type mice but not in IL-1R−/− mice. This coincided with enhanced local IL-4 production in IL-1R−/− mice. These data suggest that inhibition of local IL-1 activity may be beneficial for the outcome of BAI.

The potential role of tea in periodontal therapy: An updated review

2020 ◽  
Vol 17 ◽  
Author(s):  
Ali Forouzanfar ◽  
Hamideh Sadat Mohammadipour ◽  
Fatemeh Forouzanfar
Keyword(s):  
Green Tea ◽  
Potential Role ◽  
Wide Spectrum ◽  
Periodontal Diseases ◽  
Herbal Remedies ◽  
World Population ◽  
Tea Leaves ◽  
The World ◽  
Green Tea Leaves

: Periodontal diseases are highly prevalent and can affect high percentage of the world population. Oxidative stress and inflammation plays an important role in the pathogenesis of periodontal diseases. Nowadays, more attention has been focused on the herbal remedies in the field of drug discovery. Green tea is an important source of polyphenol antioxidants, it has long been used as a beverage worldwide. The most interesting polyphenol components of green tea leaves that are related with health benefits are the catechins. Taken together this review suggested that green tea with its wide spectrum of activities could be a healthy alternative for controlling the damaging reactions seen in periodontal diseases.

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