scholarly journals Simplified Guide to MR Elastography in Early Detection of Hepatic Fibrosis with Case Reports

Author(s):  
Amit Kharat ◽  
Nikhith Soman Vanpully ◽  
Jacob Cheeran Jeeson

AbstractThe current unhealthy diets and sedentary lifestyle have led to increase in the prevalence of diabetes and metabolic syndrome globally. Fatty liver is a common occurrence in metabolic syndrome. The liver health is often ignored due to delayed warning signs. Fatty changes of the liver is one of the common findings in ultrasonography. Ultrasound does not detect fibrosis except when cirrhosis is developed. Early stages of fibrosis are asymptomatic with no significant laboratory or preliminary imaging findings. With fibrosis, the elasticity of the liver is reduced and becomes stiffer. Over the years, many techniques have developed to assess the stiffness of the liver, starting from palpation, ultrasonography, and recently developed magnetic resonance elastography (MRE). In this article, we have tried to simplify the concepts of MRE to detect fibrosis and present few case reports. The basic steps involved in generating elastograms and interpretation with some insight on how to incorporate it into the clinical workflow are discussed. MRE is superior to various other available techniques and even offers certain advantages over biopsy. MRE is FDA approved for liver fibrosis since 2009, yet it is hardly used in the Indian setting. MRE is a safe and noninvasive technique to evaluate a large volume of the liver and can be a new norm for the evaluation of fatty liver. Magnetic resonance imaging (MRI)-based elastography techniques hold an exciting future in providing mechanical properties of tissues in various organs like spleen, brain, kidney, and heart.

Author(s):  
Ida Sofie Grønningsæter ◽  
Aymen Bushra Ahmed ◽  
Nils Vetti ◽  
Silje Johansen ◽  
Øystein Bruserud ◽  
...  

The increasing use of radiological examination, especially magnetic resonance imaging (MRI), will probably increase the risk of unintended discovery of bone marrow abnormalities in patients where a hematologic disease would not be expected. In this paper we present four patients with different hematologic malignancies of nonplasma cell types. In all patients the MRI bone marrow abnormalities represent an initial presentation of the disease. These case reports illustrate the importance of a careful diagnostic follow-up without delay of patients with MRI bone marrow abnormalities, because such abnormalities can represent the first sign of both acute promyelocytic leukemia as well as other variants of acute leukemia.


2014 ◽  
Vol 54 (9) ◽  
pp. 732-737 ◽  
Author(s):  
Masahiro Hatakeyama ◽  
Masato Kanazawa ◽  
Ayako Ishihara ◽  
Yoshinari Tanabe ◽  
Takayoshi Shimohata ◽  
...  

1989 ◽  
Vol 101 (4) ◽  
pp. 449-458 ◽  
Author(s):  
Mitchell K. Schwaber ◽  
David Zealear ◽  
James L. Netterville ◽  
Michael Seshul ◽  
Robert H. Ossoff

Magnetic resonance imaging (MRI) has been widely used in the evaluation of suspected acoustic neuroma, but has not received the same attention with respect to facial paralysis. High-resolution computed tomography (HRCT) has been the radiologic test of choice to evaluate the facial nerve. The necessary HRCT projections, slices, and enhancement techniques to visualize each segment have been outlined. We have developed a radiologic protocol that uses MRI in conjunction with HRCT, applying the strengths of each to evaluate the facial nerve. We have evaluated 15 patients and have found that MRI is the better study to evaluate the brain stem/cerebellopontine angle segment of the facial nerve and better evaluates bone-soft tissue Interfaces. HRCT is better in the evaluation of the intratemporal segment of the facial nerve and the assessment of the anatomic perspectives of a lesion within the temporal bone. The results are discussed and case reports Illustrate the efficacy of this approach.


2018 ◽  
Vol 08 (04) ◽  
pp. e201-e205 ◽  
Author(s):  
Mitsuru Kozaki ◽  
Yuko Iraha ◽  
Hitoshi Masamoto ◽  
Hayase Nitta ◽  
Yukiko Chinen ◽  
...  

AbstractTwo types of congenital bronchial atresia (proximal and peripheral) have been classified. We report two cases of peripheral bronchial atresia diagnosed by prenatal ultrasonography (US) and magnetic resonance imaging (MRI). Evaluating an enlarged lung mass that is homogeneously hyperechoic on US and hyperintense on T2-weighted MRI can help in determining whether bronchial atresia is present. Proximal type is suggested when a dilated main bronchus is observed as a tubule structure of an involved lung hilum. In our cases, T2-weighted MRI revealed homogeneously hyperintense lung lesion with decreased signal intensity of adjacent lobe, flattening diaphragm, and mediastinal shift. Dilatation of the main bronchus was not observed and the opposite lung was normal in appearance. These findings were explained by secondary compression due to enlargement of the involved lung. The preservation of vascular structure and the retained normal shape, though enlarged, in the affected lobe were observed, which demonstrated undisrupted pulmonary architecture of the lobe. Thus, congenital cystic adenomatoid malformation was excluded because pulmonary architecture was relatively preserved. Finally, presumed diagnoses of the peripheral bronchial atresia were made and confirmed by postnatal chest computed tomography.


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Xiaoyu Liu ◽  
Zining Yao ◽  
Nan Li ◽  
Kai Gao ◽  
Sheng Zhu

This paper explores the relationship between magnetic resonance diffusion-weighted imaging of nonalcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS), as well as the study of diffusion-weighted imaging, spectral imaging, and low density of nonalcoholic fatty liver correlation between serum concentration of lipoprotein cholesterol (LDL-C). This collection is from February 2018 to May 2018 in hospital as 39 cases of nonalcoholic fatty liver patients in the observation group and 39 patients in the control group with the same period of physical examination. All patients underwent magnetic resonance spectroscopy imaging, magnetic resonance diffusion-weighted imaging examination, and serum LDL-C test, compared the results of the two groups, and analysed the correlation between magnetic resonance spectroscopy imaging and magnetic resonance diffusion-weighted imaging examination results and LDL-C. The results showed that the prevalence of NAFLD was 12.33%, and the prevalence of NAFLD and MS was 3.47%. Magnetic resonance spectroscopy observation parameter group and the control group had statistically significant difference when compared ( P  < 0.05). Difference was statistically significant ( P  < 0.01). In conclusion, nonalcoholic fatty liver DWI and MR spectroscopy is closely related to LDL-C targets, quantitatively and noninvasively reflects the body’s fat metabolism, and can provide more extensive clinical diagnosis of nonalcoholic fatty liver. NAFLD is closely related to MS. The mutual aggravation and mutual promotion in the pathogenesis of the two should arouse enough attention and comprehensive prevention and treatment.


2020 ◽  
Vol 61 (12) ◽  
pp. 1695-1700
Author(s):  
Kasper Køhler Alsing ◽  
Helle Hjorth Johannesen ◽  
Rasmus Hvass Hansen ◽  
Jørgen Serup

Tattooed patients undergoing magnetic resonance imaging (MRI) can develop cutaneous complications during the procedure. Our aim was to review all published case reports on MRI-induced tattoo complications to identify a possible pattern. So far, 17 cases have been reported. Five (29%) of the cases were in cosmetic tattoos.  Symptoms are abrupt and painful with fast onset during MRI, sometimes requiring termination of the procedure. Clinical signs are absent or manifested as inflammation sensed as burning. No thermal skin burns have been recognized. Full recovery is fast, with no sequelae.  MRI-induced tattoo complications are uncommon. Patients with cosmetic and traditional tattoos can undergo routine MRI.


2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Kavitha Gopalratnam ◽  
Kevin Andrew Woodson ◽  
Jigarkumar Rangunwala ◽  
Kanaga Sena ◽  
Manisha Gupta

Ischemic strokes occur when there is a sudden obstruction of an artery supplying blood flow to an area of the brain, leading to a focal neurological deficit. Strokes can be thrombotic or embolic in etiology and are associated with underlying conditions such as hypertension and atherosclerosis. Possible etiologies of strokes include cardioembolic disease, hematologic disorders, connective tissue disorders, and substance abuse or can be cryptogenic. Most stroke cases are seen in patients over 65 years of age. However, about one-fourth of strokes occur in young adults. Iron deficiency anemia (IDA) has been described as a known cause for strokes in children, but very few case reports describe this association in adults. We describe a 20-year-old female who presented with sudden onset left side weakness. Magnetic Resonance Imaging (MRI) of the brain demonstrated ischemic infarctions. Patient was also found to be severely anemic. Patient had a thorough work-up including Magnetic Resonance Angiography (MRA) of the brain, echocardiogram, and an extensive screen for thrombophilia disorders. This, however, did not demonstrate a clear etiology. As it has been suggested that IDA is a potential cause for stroke, it is possible the stroke in this young patient was attributable to severe IDA.


1996 ◽  
Vol 17 (1) ◽  
pp. 33-36 ◽  
Author(s):  
Lawrence Yao ◽  
Andrea Cracchiolo ◽  
Keyvan Farahani ◽  
Leanne L. Seeger

Degenerative plantar plate failure is an under-recognized cause of lesser metatarsalgia. We performed magnetic resonance imaging (MRI) with a small receiver coil in 13 patients in whom plantar plate ruptures of the second or third metatarsophalangeal joint were clinically suspected. In eight patients, MRI showed focal hyperintensity in the plantar plate that was interpreted as a rupture of the plate. Ruptures were confirmed in all five patients who underwent an operative procedure to treat the unstable, painful metatarsophalangeal joint. MRI is a noninvasive technique that can visualize plantar plate abnormalities and aid the clinical evaluation of problematic lesser metatarsalgia.


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