Postcopulatory myometrial activity in the rat as seen by video-laparoscopy

1991 ◽  
Vol 3 (6) ◽  
pp. 685 ◽  
Author(s):  
LH Crane ◽  
L Martin
Keyword(s):  
Vas Deferens ◽  
Colour Change ◽  
Seminal Vesicles ◽  
Female Rats ◽  
Blue Colour ◽  
Accessory Reproductive Glands ◽  
Vaginal Plug ◽  
Prostanoid Production ◽  
Video Laparoscopy ◽  
Selection Of

Myometrial activity was analysed by video-laparoscopy in unmated and mated oestrous female rats. In the former, most contractions propagated caudally and were predominantly longitudinal, with circular contractions limited to weak peristalsis. Mating had dramatic effects on activity, inducing a high frequency of strong peristaltic and non-peristaltic circular contractions propagating both cranially and caudally. Activity remained elevated for up to 10 h, decreasing to control levels as uterine contents were lost when the vaginal plug disintegrated. Mechanical stimulation of the cervix, sufficient to induce pseudopregnancy, increased the frequency of weak peristalsis but did not induce myometrial activity comparable to that seen after mating. Treatment of mated females with indomethacin returned myometrial activity towards control levels, suggesting that myometrial stimulation involved prostanoid production. After mating to intact males the uterus took on a characteristic blue colour suggestive of hypoxia. This too was abolished by indomethacin treatment. Removal of accessory reproductive glands from males showed that induction of myometrial activity and the colour change both required constituents from the vas deferens, seminal vesicles and coagulating glands. Males lacking seminal vesicles or coagulating glands were infertile. The prolonged myometrial activity and putative hypoxia induced by seminal constituents may be important in survival and selection of sperm.

368. A direct control of the prostate and seminal vesicles via the vas deferens

1974 ◽  
Vol 5 (4) ◽  
pp. 383 ◽  
Author(s):  
C.G. Pierrepoint ◽  
P. Davies ◽  
Barbara A. John
Keyword(s):  
Vas Deferens ◽  
Seminal Vesicles ◽  
Direct Control

scholarly journals Alteration of Tissue Marking Dyes Depends on Used Chromogen during Immunohistochemistry

Cells ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 835
Author(s):  
Selina Kiefer ◽  
Julia Huber ◽  
Hannah Füllgraf ◽  
Kristin Sörensen ◽  
Agnes Csanadi ◽  
...  
Keyword(s):  
Colour Change ◽  
Residual Tumour ◽  
Blue Colour ◽  
Close Margin ◽  
Correct Orientation ◽  
Therapeutic Regime ◽  
Colour Changes ◽  
Tissue Specimens ◽  
Immunohistochemical Analyses ◽  
Colour Signal

Pathological biopsy protocols require tissue marking dye (TMD) for orientation. In some cases (e.g., close margin), additional immunohistochemical analyses can be necessary. Therefore, the correlation between the applied TMD during macroscopy and the examined TMD during microscopy is crucial for the correct orientation, the residual tumour status and the subsequent therapeutic regime. In this context, our group observed colour changes during routine immunohistochemistry. Tissue specimens were marked with various TMD and processed by two different methods. TMD (blue, red, black, yellow and green) obtained from three different providers (A, B and C, and Whiteout/Tipp-Ex®) were used. Immunohistochemistry was performed manually via stepwise omission of reagents to identify the colour changing mechanism. Blue colour from provider A changed during immunohistochemistry into black, when 3,3′-Diaminobenzidine-tetrahydrochloride-dihydrate (DAB) and H2O2 was applied as an immunoperoxidase-based terminal colour signal. No other applied reagents, nor tissue texture or processing showed any influence on the colour. The remaining colours from provider A and the other colours did not show any changes during immunohistochemistry. Our results demonstrate an interesting and important pitfall in routine immunohistochemistry-based diagnostics that pathologists should be aware of. Furthermore, the chemical rationale behind the observed misleading colour change is discussed.

scholarly journals Vas deferens invasion: A neglected issue in the sampling of radical prostatectomy materials

2014 ◽  
Vol 8 (7-8) ◽  
pp. 554 ◽  
Author(s):  
Nuri Yigit ◽  
Yildirim Karslioglu ◽  
Bulent Kurt
Keyword(s):  
Lymph Node ◽  
Radical Prostatectomy ◽  
Lymph Node Metastasis ◽  
Vas Deferens ◽  
Prognostic Significance ◽  
Seminal Vesicles ◽  
Node Metastasis ◽  
Increased Risk ◽  
Staging Systems ◽  
Independent Prognostic Significance

A radical prostatectomy affects the prostate, bilateral seminal vesicles (SV), and the distal parts of the bilateral vasa deferentia (VD). SV invasion (SVI) is associated with an increased risk of lymph node metastasis and recurrence. However, the significance of VD invasion (VDI), either with or without the involvement of their surgical margins, has not been fully appreciated. We think VDI might have an independent prognostic significance, as does SVI, and should be incorporated into the pathology guidelines and the staging systems of prostatic adenocarcinoma. Our case illustrates this.

EFFECTS OF TESTOSTERONE MEDIATED OR MODULATED BY PITUITARY FACTORS

1975 ◽  
Vol 67 (1) ◽  
pp. 71-79 ◽  
Author(s):  
P. DE MOOR ◽  
M. ADAM-HEYLEN ◽  
H. VAN BAELEN ◽  
G. VERHOEVEN
Keyword(s):  
Body Weight ◽  
Testosterone Propionate ◽  
Total Body Weight ◽  
Seminal Vesicles ◽  
Female Rats ◽  
Male Rats ◽  
Intact Male ◽  
Adult Rats ◽  
Organ Weights ◽  
Total Body

SUMMARY Adult rats of both sexes were either gonadectomized or hypophysectomized and gonadectomized. Three to eight weeks later they were treated for 14 consecutive days with oil or with 75 or 200 μg testosterone propionate (TP) per 100 g body weight. The animals were killed and for each sex the gonadectomized animals were compared with the hypophysectomized-gonadectomized animals as far as their NADPH- and NADH-dependent 3α-hydroxysteroid dehydrogenases (3α-HSD) in renal microsomes, transcortin levels in serum and five organ weights relative to total body weight were concerned. For two of the latter, i.e. the relative kidney and prostatic weights, no significant differences were found. Transcortin levels, relative adrenal weights and renal NADPH-dependent 3α-HSD activities were higher in oil-treated gonadectomized animals than in oil-treated hypophysectomized-gonadectomized animals. The opposite was found for the relative weights of uterus and seminal vesicles and renal NADH-dependent 3α-HSD activities. These differences between gonadectomized and hypophysectomized-gonadectomized animals disappeared after TP treatment as far as transcortin levels were concerned but remained for the five other parameters. After gonadectomy sexual differences subsisted for all parameters studied. But whereas intact male rats had higher NADH-dependent 3α-HSD activities than female rats the opposite was found after gonadectomy. After gonadectomy plus hypophysectomy the between sex differences disappeared as far as transcortin levels were concerned but remained in the other parameters studied.

Continued divergence in V̇o2 max of rats artificially selected for running endurance is mediated by greater convective blood O2 delivery

2006 ◽  
Vol 101 (5) ◽  
pp. 1288-1296 ◽  
Author(s):  
Norberto C. Gonzalez ◽  
Scott D. Kirkton ◽  
Richard A. Howlett ◽  
Steven L. Britton ◽  
Lauren G. Koch ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Blood Flow ◽  
Stroke Volume ◽  
High Capacity ◽  
Female Rats ◽  
O2 Delivery ◽  
Seven Generations ◽  
Cardiopulmonary System ◽  
Hypoxic Exercise ◽  
Selection Of

We previously showed that after seven generations of artificial selection of rats for running capacity, maximal O2 uptake (V̇o2 max) was 12% greater in high-capacity (HCR) than in low-capacity runners (LCR). This difference was due exclusively to a greater O2 uptake and utilization by skeletal muscle of HCR, without differences between lines in convective O2 delivery to muscle by the cardiopulmonary system (Q̇o2 max). The present study in generation 15 (G15) female rats tested the hypothesis that continuing improvement in skeletal muscle O2 transfer must be accompanied by augmentation in Q̇o2 max to support V̇o2 max of HCR. Systemic O2 transport was studied during maximal normoxic and hypoxic exercise (inspired Po2 ∼70 Torr). V̇o2 max divergence between lines increased because of both improvement in HCR and deterioration in LCR: normoxic V̇o2 max was 50% higher in HCR than LCR. The greater V̇o2 max in HCR was accompanied by a 41% increase in Q̇o2 max: 96.1 ± 4.0 in HCR vs. 68.1 ± 2.5 ml stpd O2·min−1·kg−1 in LCR ( P < 0.01) during normoxia. The greater G15 Q̇o2 max of HCR was due to a 48% greater stroke volume than LCR. Although tissue O2 diffusive conductance continued to increase in HCR, tissue O2 extraction was not significantly different from LCR at G15, because of the offsetting effect of greater HCR blood flow on tissue O2 extraction. These results indicate that continuing divergence in V̇o2 max between lines occurs largely as a consequence of changes in the capacity to deliver O2 to the exercising muscle.

C72: Osseus metaplasia of vas deferens and seminal vesicles, mimic advanced prostate cancer

2014 ◽  
Vol 13 (6) ◽  
pp. e1261
Author(s):  
B. Szabó ◽  
A. Szendrői ◽  
M. Kardos ◽  
P. Bata ◽  
P. Nyirády
Keyword(s):  
Prostate Cancer ◽  
Advanced Prostate Cancer ◽  
Vas Deferens ◽  
Seminal Vesicles

Lannea acida improves the emission phase of ejaculation of mature male rat: effects on vas deferens and seminal vesicles

2019 ◽  
Vol 11 (1) ◽  
pp. 54
Author(s):  
Pierre Watcho ◽  
Aimé Césaire Momo Tetsatsi ◽  
Modeste Wankeu-Nya ◽  
Georges Romeo Bonsou Fozin ◽  
François Xavier Kemka Nguimatio ◽  
...  
Keyword(s):  
Vas Deferens ◽  
Seminal Vesicles ◽  
Mature Male ◽  
Male Rat ◽  
Emission Phase

Urethral plug-a new secondary male sex characteristic in rat and other rodents

1982 ◽  
Vol 16 (2) ◽  
pp. 151-155 ◽  
Author(s):  
Ivo Kunstýř ◽  
Werner Küpper ◽  
Herwig Weisser ◽  
Susanne Naumann ◽  
Claus Messow
Keyword(s):  
Amino Acid ◽  
Amino Acid Composition ◽  
Adult Male ◽  
Seminal Vesicles ◽  
Male Rats ◽  
Average Weight ◽  
Adult Rats ◽  
Vaginal Plug ◽  
Male Sex ◽  
Proximal Urethra

The plug is an eosinophilic mass, partly homogenous and partly porous, filling the proximal urethra in rats and occasionally extending into the bladder. Its average weight in 131 adult rats was 0·063 g. These plugs are normally present in the urethra of adult male rats, and this seems to be the case for all laboratory Muridae and Cavidae. The absence of a plug in an adult male may be a sign of abnormality associated with failing health. There is an interesting similarity between the amino acid composition of the content of seminal vesicles, that of the urethral plug, and that of the copulatory vaginal plug in female rodents.

Sign in / Sign up

Export Citation Format

Share Document