Evaluation of the biological activity of crude extracts from plants used in Yucatecan Traditional Medicine. Part II. DNA-interacting activity

Phytomedicine ◽  
2001 ◽  
Vol 8 (3) ◽  
pp. 236-239 ◽  
Author(s):  
A. Sánchez-Medina ◽  
K. García-Sosa ◽  
F. May-Pat ◽  
L.M. Peña-Rodríguez
2009 ◽  
Vol 3 (4) ◽  
pp. 134-140 ◽  
Author(s):  
A.V. Babu ◽  
R.S.C. Rao ◽  
K.G. Kumar ◽  
B.H. Babu ◽  
P.V.V. Satyanaray

2016 ◽  
Vol 30 (15) ◽  
pp. 1766-1770 ◽  
Author(s):  
I. Podolak ◽  
M. Olech ◽  
A. Galanty ◽  
D. Załuski ◽  
K. Grabowska ◽  
...  

Author(s):  
AMERENDRA SINGH ◽  
JAI NARAYAN MISHRA ◽  
SANTOSH KUMAR SINGH

In the current years, the use of traditional medicine is increasing and gaining popularity. The extracts of Moringa concanensis Nimmo leaves have reported many medicinal uses. In the previous few decades, a massive quantity of scientific facts concerning plants, crude extracts, and quite a number supplies from plant life as medicinal dealers has come to light. M. concanensis is a plant whose components are oftentimes used in the medicinal treatments. There are good sized anecdotal facts about the organic undertaking of M. concanensis which includes anticancerous, antibacterial, antifungal, analgesic, and anti-inflammatory type of activities. The leaves of M. concanensis had been located to contain a higher quantity of triterpenoids and flavonoids. The existing assessment includes the phytochemical, ethnopharmacological, and pharmacological reviews of M. concanensis. The future scope of the plant has been emphasized with a view to isolate bioactive moieties which should be used for multifarious biological activities.


2017 ◽  
Vol 14 (4) ◽  
pp. 1235-1250 ◽  
Author(s):  
Elsa Dilla Dertyasasa ◽  
Woro Anindito Sri Tunjung

ABSTRACT: Previous studies have reported that a number of organic compounds are present in kaffir lime (Citrus hystrix DC.) leaf extracts. Further research is needed to purify these compounds and determine which are biologically active. The objective of this study is to identify the volatile organic compounds of kaffir lime leaf crude extracts and fractions and to study their bioactivity. Fractionation was performed by the double maceration method, using hexane as the second solvent. TLC was performed to analyze the qualitative separation, whereas the individual constituents were detected using GC-MS. Our results showed that chloroform and ethyl acetate crude extracts contained various volatile organic compounds such as fatty acids, fatty alcohols, prenol lipids, sterol lipids, terpenoids and long chain alkanes. Fractionation separated these compounds into non-hexane fractions, which contained less volatile compounds, and hexane fractions. The volatile compounds of non-hexane fractions were identified to be long chain alkanes, meanwhile the hexane fractions contained terpenoids, fatty acids, fatty alcohols, prenol lipids and sterol lipids. Palmitic acid and terpenoids, such as citronellyl propionate, nerolidol, citronella and caryophyllene oxide were found to be the most dominant bioactive compounds in chloroform and ethyl acetate crude extract and their hexane fractions, which were reported to possess cytotoxicity against cancer cells. Meanwhile in non-hexane fractions, long chain alkanes such as triacontane and hentriacontane were found to be the most dominant bioactive compound which also possessed cytotoxic effect. In conclusion, fractionation using the double maceration method yielded different volatile organic compounds composition with different biological activities. The crude extracts and fractions of kaffir lime leaves were potential to be developed as a traditional medicine for cancer treatment.


2020 ◽  
Vol 17 (3) ◽  
pp. 309-322 ◽  
Author(s):  
Carlos Magno Rocha Ribeiro ◽  
Thiago Silva Galvão de Souza ◽  
Karinne Canevalli de Almeida ◽  
Karen Danielle Borba Dutra ◽  
Alessandra Leda Valverde

: Heliannuols are an important class of compounds isolated from Helianthus annuus, a common sunflower, with allelopathic properties. Interestingly, two of these fourteen compounds have been isolated from a gorgonian, Pseudopterogorgia rigida. This review compiles data on the isolation and biological activity of heliannuols described in the literature and briefly reports the papers describing their syntheses. This review could stimulate research into other natural species and syntheses. Further, it describes the 1H and 13C-NMR spectral data described in the literature for the 14 heliannuols already isolated and correlates them with their respective structures. Therefore, we believe that these searchable data enable a rapid identification in routine analysis of the crude extracts of sunflowers or gorgonians.


2014 ◽  
Vol 9 (9) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Hiatzy E. Zapata-Estrella ◽  
Azeret D. M. Sánchez-Pardenilla ◽  
Karlina García-Sosa ◽  
Fabiola Escalante-Erosa ◽  
Fátima de Campos-Buzzi ◽  
...  

The bioassay-guided purification of the ethanol extracts of Acmella pilosa and Cnidoscolus souzae, two plants of the native flora of the Yucatan Peninsula used in traditional medicine to treat inflammation and pain, resulted in the identification of rosmarinic acid (1) and caffeic acid (2) as the bioactive metabolites from A. pilosa, and of 7-deoxynimbidiol (4) as the major bioactive metabolite from C. souzae. Metabolites 1, 2, and 4 proved to be responsible for the antioxidant activity originally detected in the corresponding organic crude extracts; 7-deoxynimbidiol (4) showed good analgesic and anti-inflammatory activities, inhibiting the pain induced by PGE2 and reducing the edema induced by carrageenan, respectively.


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