scholarly journals Flavonoid and phenolic acid profile by LC-MS/MS and biological activity of crude extracts from Chenopodium hybridum aerial parts

2016 ◽  
Vol 30 (15) ◽  
pp. 1766-1770 ◽  
Author(s):  
I. Podolak ◽  
M. Olech ◽  
A. Galanty ◽  
D. Załuski ◽  
K. Grabowska ◽  
...  
2016 ◽  
Vol 32 (3) ◽  
pp. 1439-1451 ◽  
Author(s):  
Majid Mohammad hosseini ◽  
Abolfazl Akbarzadeh ◽  
Hamid Hashemi-Moghaddam ◽  
Mahdiyeh Shahnama ◽  
Bijan Fahimi ◽  
...  

2009 ◽  
Vol 3 (4) ◽  
pp. 134-140 ◽  
Author(s):  
A.V. Babu ◽  
R.S.C. Rao ◽  
K.G. Kumar ◽  
B.H. Babu ◽  
P.V.V. Satyanaray

2016 ◽  
Vol 11 (5) ◽  
pp. 1934578X1601100 ◽  
Author(s):  
Tran Minh Hoi ◽  
Tran Van Thai ◽  
Chu Thi Thu Ha ◽  
Ha Thi Van Anh ◽  
Phan Xuan Binh Minh ◽  
...  

One new flavonol diglycoside, 4′,5-dihydroxy-3,3′,7-trimethoxyflavone 4′- O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (1), and two known compounds (2–3) were isolated from the methanol extract of Anoectochilus annamensis Aver. aerial parts. The effects were evaluated of all isolated compounds (1–3) on LPS-induced production of the inflammatory mediator nitric oxide (NO) by RAW264.7 cells. 4′,5-Dihydroxy-3,3′,7-trimethoxyflavone (2) was the most active while the addition of a rutinoside at C-4′ (compound 1) decreased the inhibitory activity. This is the first report on the chemical composition and biological activity of A annamensis.


Phytomedicine ◽  
2001 ◽  
Vol 8 (3) ◽  
pp. 236-239 ◽  
Author(s):  
A. Sánchez-Medina ◽  
K. García-Sosa ◽  
F. May-Pat ◽  
L.M. Peña-Rodríguez

2010 ◽  
Vol 5 (10) ◽  
pp. 1934578X1000501 ◽  
Author(s):  
Branislav Šiler ◽  
Danijela Mišić ◽  
Jasmina Nestorović ◽  
Tijana Banjanac ◽  
Jasmina Glamočlija ◽  
...  

The main principles of C. pulchellum (Sw.) Druce, secoiridoid glycosides, have been studied as potent bioactive compounds. Here we scored their content in extracts of ten populations of this species. Antibacterial and antifungal assays of the extracts and pure secoiridoid glycosides were performed against eight bacterial strains and five fungal species. Methanol extracts from both aerial parts and roots exhibited excellent antibacterial (0.05-0.2 mg mL−1) and very good antifungal (0.1-2 mg mL−1) activity. Pure secoiridoid glycosides isolated from these extracts demonstrated very strong antibacterial (0.01-0.04 mg mL−1) and especially antifungal (0.001-0.1 mg mL−1) activity.


Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 577 ◽  
Author(s):  
Yongzhe Dong ◽  
Jingya Ruan ◽  
Zhijuan Ding ◽  
Wei Zhao ◽  
Mimi Hao ◽  
...  

To clarify whether flavonoids and phenols in Allium mongolicum Regel have the effect of improving gastrointestinal function and analyze its quality, this study was designed to isolate and identify them from the aerial parts of A. mongolicum by using various chromatographic and spectrophotometric methods, a bioassay on motility of mouse isolated intestine tissue, as well as qualitative analysis using liquid chromatography/mass spectrometry (LC-MS) analysis. As a result, 31 flavonoids and phenolic acids were obtained and identified, including six new flavonoid glycosides, mongoflavonosides A1 (1), A2 (2), A3 (3), A4 (4), B1 (5), B2 (6), and four new phenolic acid glycosides, mongophenosides A1 (7), A2 (8), A3 (9), B (10). Among them, eleven flavonoids and three phenolic acids showed significant increase in the height of mouse small intestinal muscle. It was a first systematic bioactive constituents’ study for A. mongolicum on gastrointestinal tract. Furthermore, according to the retention time (tR) and the exact mass-to-charge ratio (m/z), thirty-one compounds were unambiguously identified by comparing to the standard references by using LC-MS. Then, on the basis of generalized rules of MS/MS fragmentation pattern, chromatographic behaviors, as well as biosynthetic laws of the 31 isolates, five flavonoid glycosides and one phenolic acid glycoside were tentatively speculated. On the basis of the study, a fast analysis method for flavonoids and phenolic acids in A. mongolicum was established.


Author(s):  
Alaa M. Abd ◽  
Enas J. Kadhim

 The aim of this study was to study chemical constituents of aerial parts of Cardaria draba since no phytochemical investigation had been studied before in Iraq. Aerial parts of Cardaria draba were defatted by maceration in hexane for 72 h. The defatted plant materials were extracted using Soxhlet apparatus, the aqueous Methanol 90% as a solvent extraction for 18 h, and fractionated with petroleum ether- chloroform (CHCl3)- ethylacetate- and n-butanol respectivly. The ethyl acetate, n-butanol, and n-butanol after hydrolysis fractions were investigated by high performance liquid chromatography (HPLC) and thin-layer chromatography (TLC) for its phenolic acid and flavonoid contents. Flavonoids and phenolic acid derivative were isolated from the ethylacetate of leaf fraction and n-butanol after hydrolysis fraction of the aerial parts and identified by TLC, FTIR and HPLC. A various chromatographic and spectroscopic results shown the presence of luteolin, chlorogenic acid, caffeic acid, and resorcinol in aerial parts of C. draba.                                                                                                                              


2020 ◽  
pp. 19-45
Author(s):  
Natal'ya Valeriyevna Petrova ◽  
Nina Anatol'yevna Medvedeva

The subject of the review is the component composition and biological activity of species of genus Viola L. (Violaceae) from the flora of the Russian Federation according publications appeared over the past few decades. Chemical constituents and biological activities have been reported for 24 species of the 100 Viola species occurring in Russian. Components of various structures: flavonoids, cyclotides, anthocyanidins, phenylpropanoic acids, coumarins, alkaloids, fatty acids and its derivatives and ect. were found in the roots, aerial parts, flowers and leaves. Composition of 137 flavonoids, alkaloids, coumarins etc. was expanded with references to their chemical formulas and literature sources. Data of the essential oils isolated from the leaves of V. tricolor L., V. arvensis Murray, V. yedoensis Makino и V. odorata L. is systematized. It was demonstrated that extracts, their fractions, and some components showed different types of biological activity, including anti-inflammatory, cytotoxic and antiviral ones. The revealed range of biological activity partially confirmed expediency of using species of genus Viola in folk and standard practice medicine.


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