Evaluation of combined medical and surgical treatment in nasal polyposis – III. Correlation between symptoms and CT scores before and after surgery for nasal polyposis

OBJECTIVE: To correlate the levels of interleukins 1 β, 3, 4, and 5 before and after surgery and compare the levels between patients with and without recurrence of nasal polyposis. STUDY DESIGN AND SETTING: Thirty-nine patients with NP were selected, 13 of them allergic and 26 nonallergic. A control group of 11 individuals was also studied. The concentrations of interleukins were measured by enzyme-linked immunosorbent assay. RESULTS: There was a higher incidence of NP after the fourth decade of life and among men. The clinical symptoms were similar in both groups of patients with nasal polyposis and characterized by nasal obstruction and anosmia. A significant reduction of all interleukins studied was observed after surgical treatment. CONCLUSION: Levels of interleukins 1β, 3, 4, and 5 were significantly reduced after surgery and the levels of interleukins 1β and 5 were significantly lower in patients without recurrence of nasal polyposis after surgery when compared to those with recurrence.

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Comparison of the State of Sleep in Patients with Sleep-disordered Breathing Before and After Surgical Treatment

Acta Oto-Laryngologica ◽

10.1080/0365523031000054 ◽

2003 ◽

Vol 123 (0) ◽

pp. 51-55

Author(s):

Munenori Hayakawa ◽

Tadao Nishimura ◽

Kenji Suzuki ◽

Natsuki Morishima ◽

Nobuhiro Shibata ◽

...

Keyword(s):

Surgical Treatment ◽

Sleep Disordered Breathing ◽

The State ◽

Before And After ◽

Disordered Breathing

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Gustatory Function after Radiofrequency Tongue Base Reduction in Patients with Obstructive Sleep Apnea

Otolaryngology ◽

10.1177/0194599811413680 ◽

2011 ◽

Vol 145 (5) ◽

pp. 853-857 ◽

Cited By ~ 4

Author(s):

Young Gyu Eun ◽

Seung Youp Shin ◽

Jae Yong Byun ◽

Myung Gu Kim ◽

Kun Hee Lee ◽

...

Keyword(s):

Obstructive Sleep Apnea ◽

Surgical Treatment ◽

Sleep Apnea ◽

Medical Center ◽

Tongue Base ◽

Safe Procedure ◽

Gustatory Function ◽

Obstructive Sleep ◽

Before And After ◽

Tongue Base Reduction

Objectives. To investigate the changes in gustatory function as a complication after radiofrequency tongue base reduction (RTBR) in patients with obstructive sleep apnea (OSA). Study Design. Before-and-after study. Setting. Academic tertiary medical center. Subjects and Methods. Thirty-four patients with suspected velopharyngeal collapse only underwent uvulopalatopharyngoplasty (UPPP group). Twenty-five patients with velopharyngeal and retrolingual collapse underwent concurrent UPPP with RTBR (RTBR group). All patients were evaluated before surgery and at 1 and 4 weeks after surgical treatment. A questionnaire was given to assess symptoms of hypogeusia, dysgeusia, hyposmia, and sensation of the tongue. Electrogustometry (EGM) in 4 areas was used to determine gustatory function. Results. Postoperative values for subjective symptoms did not significantly change following surgical treatment in either group. EGM thresholds of all tested in both groups did not significantly change 1 week and 4 weeks after surgery. Conclusions. Gustatory function remained unchanged after RTBR in patients with OSA. The authors suggest that RTBR is a safe procedure in terms of taste sensation in OSA patients.

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Comparison of montelukast and mometasone furoate in the prevention of recurrent nasal polyps

Therapeutic Advances in Respiratory Disease ◽

10.1177/1753465811427577 ◽

2011 ◽

Vol 6 (1) ◽

pp. 5-10 ◽

Cited By ~ 21

Author(s):

Erkan Vuralkan ◽

Cem Saka ◽

Istemihan Akin ◽

Sema Hucumenoglu ◽

Binnur Uzmez Unal ◽

...

Keyword(s):

Recurrence Rate ◽

Nasal Spray ◽

Peripheral Blood ◽

Nasal Polyposis ◽

Mometasone Furoate ◽

Significant Difference ◽

Before And After ◽

Group A ◽

Group B ◽

Snot 22

Background: The aim of our study was to compare the effects of montelukast and mometasone furoate nasal spray on the postoperative course of patients with nasal polyposis. Patients and methods: Fifty patients diagnosed with nasal polyposis between March 2006 and August 2007 were included in the study. All patients underwent bilateral endoscopic sphenoethmoidectomy and were randomized postoperatively into two groups. Group A ( n = 25) received 10 mg montelukast per day and group B ( n = 25) received 400 µg mometasone furoate nasal spray twice daily. All patients were followed up for 6 months. Sino-Nasal Outcome Test (SNOT)-22 scores, polyp grades, computerized tomography (CT) scores (Lund–Mackay), eosinophils in peripheral blood and polyp tissue were evaluated before and after surgery. Results: There was a significant reduction in SNOT-22 scores in both groups throughout the study period. There was a significant difference in the recurrence rate between both groups with a marginal advantage of mometasone furoate nasal spray. Eosinophils in peripheral blood were found to be effective on the recurrence rate ( p < 0.05). Conclusions: In conclusion, both drugs seem to have a complementary action and further studies are needed to determine which patients should receive which treatment.

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Stereopsis before and after surgical treatment for constant versus intermittent exotropia

Oftalmologicheskii Zhurnal ◽

10.31288/oftalmolzh202132327 ◽

2021 ◽

Vol 92 (3) ◽

pp. 23-27

Author(s):

I. M. Boichuk ◽

◽

Alui Tarak ◽

◽

Keyword(s):

Surgical Treatment ◽

Intermittent Exotropia ◽

Before And After ◽

Constant Versus

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Classifications for Proliferative Vitreoretinopathy (PVR): An Analysis of Their Use in Publications over the Last 15 Years

Journal of Ophthalmology ◽

10.1155/2016/7807596 ◽

2016 ◽

Vol 2016 ◽

pp. 1-6 ◽

Cited By ~ 11

Author(s):

Salvatore Di Lauro ◽

Mustafa R. Kadhim ◽

David G. Charteris ◽

J. Carlos Pastor

Keyword(s):

Clinical Practice ◽

Surgical Treatment ◽

Proliferative Vitreoretinopathy ◽

Original Description ◽

Therapy Outcome ◽

Outcome Parameters ◽

Classification Errors ◽

Before And After ◽

Pubmed Search ◽

The Way

Purpose. To evaluate the current and suitable use of current proliferative vitreoretinopathy (PVR) classifications in clinical publications related to treatment.Methods. A PubMed search was undertaken using the term “proliferative vitreoretinopathy therapy”. Outcome parameters were the reported PVR classification and PVR grades. The way the classifications were used in comparison to the original description was analyzed. Classification errors were also included. It was also noted whether classifications were used for comparison before and after pharmacological or surgical treatment.Results. 138 papers were included. 35 of them (25.4%) presented no classification reference or did not use any one. 103 publications (74.6%) used a standardized classification. The updated Retina Society Classification, the first Retina Society Classification, and the Silicone Study Classification were cited in 56.3%, 33.9%, and 3.8% papers, respectively. Furthermore, 3 authors (2.9%) used modified-customized classifications and 4 (3.8%) classification errors were identified. When the updated Retina Society Classification was used, only 10.4% of authors used a full C grade description. Finally, only 2 authors reported PVR grade before and after treatment.Conclusions. Our findings suggest that current classifications are of limited value in clinical practice due to the inconsistent and limited use and that it may be of benefit to produce a revised classification.

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Correction of gastrocardial syndrome in patients with hernias of the esophageal orifice of the diaphragm during antireflux operations

Medical Council ◽

10.21518/2079-701x-2021-21-2-62-71 ◽

2022 ◽

pp. 62-71

Author(s):

T. V. Khorobrykh ◽

A. A. Voevodina ◽

D. A. Efremov ◽

V. I. Korotkiy ◽

N. R. Khusainova ◽

...

Keyword(s):

Surgical Treatment ◽

Angina Pectoris ◽

Hiatal Hernia ◽

Reflux Esophagitis ◽

Antireflux Surgery ◽

Pain Syndrome ◽

Ecg Monitoring ◽

Younger Age ◽

Before And After ◽

Antireflux Operations

Introduction. Hernia of the esophageal opening of the diaphragm in 90% of cases is the main cause of the development of reflux esophagitis. The doctrine highlighted a large group of extraesophageal manifestations of reflux esophagitis, including gastrocardiac syndrome.Аim. The purpose of this publication is to evaluate the effectiveness of antireflux surgery in patients with hiatal hernia through the prism of its effectiveness in the dynamics of gastrocardial syndrome regression.Material and мethods. The paper presents the results of diagnostics and surgical treatment of 101 patients with hiatal hernia.Results. According to the data of instrumental research methods, cardiac hernias of the esophageal opening of the diaphragm were detected in 45 (44.5%) patients, cardiofundal in 40 (39.6%), subtotal in 15 (14.8%), total in 1 (0.9%). The main place in the clinical picture of gastrocardial syndrome was occupied by the pain syndrome behind the breastbone (83.1%). Thus, arrhythmias were found in 16 (40.0%) patients with cardiofundal, in 10 (66.6%) subtotal and in 1 (100.0%) total hiatal hernia, and angina pectoris is characteristic of cardiac hernias and was observed in 20 (44.4%) patients. The clinical manifestation of reflex angina pectoris and arrhythmias depended on the degree of shortening of the esophagus. Thus, arrhythmias were more common in patients with cardiofundal (50.0%), subtotal (71.4%), total (100.0%) hiatal hernia with II degree of shortening of the esophagus, and angina pectoris characteristic of cardiac (75.0%) hiatal hernia. with II degree of shortening of the esophagus. Reflex angina is typical for patients of the older age group, and manifestations of arrhythmia are recorded at a younger age. Heart rate variability was considered, according to electrocardiogram and Holter ECG monitoring before and after surgical treatment, where the parameters significantly (p> 0.05) decreased.Conclusions. The phenomena of gastrocardial syndrome regressed after antireflux surgery in 44 (43.5%) patients. Surgical treatment from the endovideosurgical approach did not worsen the results of surgical treatment.

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PREVENTION AND TREATMENT OF VENOUS THROMBOSIS AND THROMBOEMBOLISM IN SURGICAL TREATMENT PELVIC NEOPLASMS

Kharkiv Surgical School ◽

10.37699/2308-7005.3.2020.15 ◽

2020 ◽

pp. 74-80

Author(s):

A. V. Chikin

Keyword(s):

Surgical Treatment ◽

Venous Thrombosis ◽

Vena Cava ◽

Fold Increase ◽

Initial State ◽

Pelvic Neoplasms ◽

Surgical Interventions ◽

Vein Thrombosis ◽

Prevention And Treatment ◽

Before And After

Summary. Venous thromboembolic complications — a collective concept that combines thrombosis of the saphenous and deep veins, as well as pulmonary thromboembolism. In the clinical practice of a doctor of any specialty, especially surgical, the possibility of timely diagnosis, treatment and preventive measures for deep vein thrombosis and pulmonary embolism are extremely important. Purpose. To study the most informative measures for the prevention and treatment of venous thrombosis and thromboembolism in the surgical treatment of pelvic neoplasms. Materials and methods. The analysis of the results of the examination and treatment of 112 patients observed for tumors of the pelvic organs and tumors of the retroperitoneal space is presented. Results and discussion. When studying the initial state of the hemostasis system in 48 patients, a significant shortening of activated partial thromboplastin time (APTT), a 1.5-fold increase in the concentration of fibrinogen, which indicates activation of the procoagulant link, as well as an increase in platelet aggregation by 20.0 %, were established. Studies of the hemostatic system showed that surgical interventions and injuries contribute to increased hypercoagulation. Conclusions. The most informative methods for determining thrombosis in the system of the inferior vena cava and the optimal examination algorithm are: ultrasonic dynamic angioscanning, determination of the amount of D-dimer, computer, magnetic resonance bolus venography and retrograde ileocavagography. The use of unfractionated and low molecular weight heparins effectively prevents the development of thrombosis and thromboembolism before and after surgery and does not cause bleeding. Nonspecific and specific prophylaxis of venous thrombosis and embolism allowed a 2.8-fold reduction in their number in patients of the main group.

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