Gender convergence or divergence in the relationship between late-life depression and multiple stressors: evidence from a national survey in China

AbstractThis brief report provides an introduction to the topic of cognitive functioning in late-life depression (LLD). In addition to providing a review of the literature, we present a framework for understanding the heterogeneity of cognitive outcomes in this highly prevalent disorder. In addition, we discuss the relationship between LLD and dementia, and highlight the importance of regularly assessing cognitive functioning in older adults who present with depressive symptoms. If cognitive deficits are discovered during a neuropsychological assessment, we recommend referral to a geriatric psychiatrist or cognitive neurologist, for evaluation and treatment of the patient’s symptoms. (JINS, 2014, 20, 1–7)

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The relationship of frailty and disability with suicidal ideation in late life depression

Aging & Mental Health ◽

10.1080/13607863.2019.1698514 ◽

2019 ◽

pp. 1-6 ◽

Cited By ~ 3

Author(s):

David Bickford ◽

Ruth T. Morin ◽

Cara Woodworth ◽

Elizabeth Verduzco ◽

Maryam Khan ◽

...

Keyword(s):

Suicidal Ideation ◽

Late Life ◽

Late Life Depression ◽

Relationship Of ◽

The Relationship

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BROODING MODERATES THE RELATIONSHIP BETWEEN CEREBROVASCULAR BURDEN AND VASCULAR DEPRESSION

Innovation in Aging ◽

10.1093/geroni/igz038.3216 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

pp. S877-S878

Author(s):

Manuel Herrera Legon ◽

Daniel Paulson

Keyword(s):

Older Adults ◽

Depressive Symptomatology ◽

Depression Scale ◽

Late Life ◽

Community Dwelling ◽

Self Report ◽

Future Research ◽

Late Life Depression ◽

Vascular Depression ◽

The Relationship

Abstract Objective: The vascular depression hypothesis posits that cerebrovascular burden confers risk for late-life depression. Though neuroanatomical correlates of vascular depression (prefrontal white matter hyperintensities) are well established, little is known about cognitive correlates; the identification of which may suggest therapeutic targets. Aims of this study are to examine the hypothesis that the relationship between cerebrovascular burden and depressive symptoms is moderated by brooding, a type of rumination. Method: A sample of 52 community-dwelling, stroke-free, individuals over the age of 70, without history of severe mental illness or dementia completed the Ruminative Responses Scale, and provided self-report (cardiac disease, hypertension, diabetes, high cholesterol) CVB data. The Geriatric Depression Scale was used to assess depressive symptomatology. Results: Results of a bootstrapped model were that self-reported measures of CVB predicted depressive symptomatology. This relationship was significantly moderated by brooding. Among older adults, those who self-reported high CVB and medium to elevated levels of rumination experienced disproportionately more depressive symptomatology. Conclusions: These findings suggest that brooding rumination may be one correlate of the vascular depression syndrome. Future research should examine neuroanatomical correlates of rumination among older adults, and further explore brooding as a therapeutic target for those with late-life depression.

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Depression and mild cognitive impairment – Comorbidity and/or continuum?

European Psychiatry ◽

10.1016/j.eurpsy.2016.01.430 ◽

2016 ◽

Vol 33 (S1) ◽

pp. S190-S191

Author(s):

G. Sobreira ◽

M.A. Aleixo ◽

C. Moreia ◽

J. Oliveira

Keyword(s):

Risk Factors ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Cognitive Decline ◽

Late Life ◽

The Elderly ◽

Late Life Depression ◽

Pubmed Database ◽

Competing Interest ◽

The Relationship

IntroductionDepression and mild cognitive impairment are common among the elderly. Half the patients with late-life depression also present some degree of cognitive decline, making the distinction between these conditions difficult.ObjectivesTo conduct a database review in order to understand the relationship between these entities, and treatment approaches.AimsTo create and implement clinical guidelines at our institution, to evaluate and treat elderly patients presenting with depression and mild cognitive impairment.MethodsA PubMed database search using as keywords “late life depression”, “depression”; “cognitive impairment”; “mild cognitive impairment” and “dementia” between the year 2008 and 2015.ResultsLate-life depression and cognitive impairment are frequent among the elderly (10–20%). Depression is also common in the early stages of dementia decreasing as the cognitive decline progresses. The causal relationship between these entities is not well understood and some authors advocate a multifactorial model (genetic risk factors; neuroendocrine changes; vascular risk factors) and the cognitive impairment of said changes is dependent on the individual's cognitive reserve. Regarding treatment of depression in patients with cognitive impairment, most authors advocate a stepped approach with watchful waiting and then, if symptoms persist, the introduction of pharmacotherapy and psychosocial intervention.ConclusionsThe relationship between cognitive impairment and depression is still not clear and probably multifactorial. The diagnosis of depressive symptoms in patients with severe cognitive impairment can be difficult and most forms of pharmacological treatment in this population are not beneficial, making it important to carefully evaluate the benefits of introducing new medication.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Module 3: Doing Tools

Treating Late Life Depression ◽

10.1093/med-psych/9780195383706.003.0003 ◽

2009 ◽

pp. 31-58

Author(s):

Larry W. Thompson ◽

Leah Dick-Siskin ◽

David W. Coon ◽

David V. Powers ◽

Dolores Gallagher-Thompson

Keyword(s):

Problem Solving ◽

Behavioral Activation ◽

Late Life ◽

Activity Monitoring ◽

Late Life Depression ◽

The Relationship ◽

Pleasant Events

This chapter outlines active tools to help with CBT for late-life depression, including behavioral activation, activity monitoring, scheduling pleasant activities, breaking tasks into manageable pieces, and exploring thoughts and expectations. It also discusses the importance of pleasant activities, monitoring mood, the California Older Person’s Pleasant Events Schedule (COPPES), and graphing the relationship between pleasant events and mood, as well as problem-solving steps and techniques.

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Age-Related Hearing Loss and the Development of Cognitive Impairment and Late-Life Depression: A Scoping Overview

Seminars in Hearing ◽

10.1055/s-0041-1725997 ◽

2021 ◽

Vol 42 (01) ◽

pp. 010-025

Author(s):

Rahul K. Sharma ◽

Alexander Chern ◽

Justin S. Golub

Keyword(s):

Hearing Loss ◽

Social Isolation ◽

Late Life ◽

Later Life ◽

Late Life Depression ◽

Age Related ◽

Impaired Cognition ◽

Behavioral Mechanisms ◽

Age Related Hearing Loss ◽

The Relationship

AbstractAge-related hearing loss (ARHL) has been connected to both cognitive decline and late-life depression. Several mechanisms have been offered to explain both individual links. Causal and common mechanisms have been theorized for the relationship between ARHL and impaired cognition, including dementia. The causal mechanisms include increased cognitive load, social isolation, and structural brain changes. Common mechanisms include neurovascular disease as well as other known or as-yet undiscovered neuropathologic processes. Behavioral mechanisms have been used to explain the potentially causal association of ARHL with depression. Behavioral mechanisms include social isolation, loneliness, as well as decreased mobility and impairments of activities of daily living, all of which can increase the risk of depression. The mechanisms underlying the associations between hearing loss and impaired cognition, as well as hearing loss and depression, are likely not mutually exclusive. ARHL may contribute to both impaired cognition and depression through overlapping mechanisms. Furthermore, ARHL may contribute to impaired cognition which may, in turn, contribute to depression. Because ARHL is highly prevalent and greatly undertreated, targeting this condition is an appealing and potentially influential strategy to reduce the risk of developing two potentially devastating diseases of later life. However, further studies are necessary to elucidate the mechanistic relationship between ARHL, depression, and impaired cognition.

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