Off-label-prescriptions in daily clinical practice – a cross-sectional national survey of palliative medicine physicians

(1) Background: Opioid use disorder (OUD) is a complex condition that can require long-term treatment. Pharmacological therapy for OUD involves treatment with opioid agonists (OMT) tailored to individual profiles. The aim of our study in daily clinical practice was to compare the profiles of patients treated with methadone (MTD) and those using buprenorphine (BHD or BHD-naloxone-NX). (2) Methods: A cross-sectional multicentre study explored the psychological, somatic and social profiles of patients with Opioid Use Disorder (OUD) following Opioid Maintenance Treatment (BHD, BHD/NX, or MTD). Descriptive and comparative analyses were performed (3) Results: 257 patients were included, a majority were men using heroin. 68% (178) were on MTD, 32% (79) were on BHD. Patients with MTD were significantly more likely to report socio-affective damage, and more likely to be younger and not to report oral or sublingual use as the main route for heroin or non-medical opioids (4) Conclusions: In daily clinical practice, regarding OUD damage, only socio-affective damage was significantly more prevalent among patients on MTD than among those on BHD in the multivariate model. Age and route of administration also differed, and our results could raise the issue of the type of OMT prescribed in case of non-medical use of prescribed opioids. These hypothesis should be confirmed in larger studies.

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Master of Science in Nursing students’ expectations to participate in nursing research-related tasks in clinical practice after completing their education – A cross-sectional survey

Journal of Nursing Education and Practice ◽

10.5430/jnep.v10n5p1 ◽

2019 ◽

Vol 10 (5) ◽

pp. 1

Author(s):

Connie Berthelsen ◽

Bente Martinsen ◽

Marianne Vamosi

Keyword(s):

Clinical Practice ◽

Nursing Students ◽

Improve Patient Care ◽

Cross Sectional Study ◽

Daily Clinical Practice ◽

Nursing Research ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Convenience Sample ◽

Master Of Science

Objective: To describe Master of Science in Nursing students’ expectations to participate in nursing research-related tasks in daily clinical practice after completing their education.Methods: To support this assumption a descriptive cross-sectional study was conducted to describe Master of Science in nursing students’ expectations to participate in nursing research-related tasks in daily clinical practice after completing their education. Data were collected using a 41-item structured questionnaire.Results: A convenience sample of Master of Science in Nursing students (n = 116) was recruited during their third semester and 92 (79.3%) students replied the questionnaire. The results showed how 91.3% of the students expressed high expectations regarding their possibilities for participation in nursing research-related tasks in clinical practice. However, 64.1% doubted that time and resources would be allocated to nursing research.Conclusions: The key motivator for the students was to improve patient care, further develop clinical practice, and strengthen the nursing profession. However, the literature suggests that colleagues and the nursing management in clinical practice impose certain barriers that prevent nurses from participating in research.

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Antihypertensive treatment and blood pressure control in patients with hypertension in daily clinical practice: a cross-sectional, multicenter, observational study in Egypt

Current Medical Research and Opinion ◽

10.1080/03007995.2016.1232706 ◽

2016 ◽

Vol 33 (1) ◽

pp. 39-45 ◽

Cited By ~ 3

Author(s):

Ramzy El Mawardy ◽

Ashraf Okba

Keyword(s):

Blood Pressure ◽

Clinical Practice ◽

Observational Study ◽

Blood Pressure Control ◽

Antihypertensive Treatment ◽

Pressure Control ◽

Daily Clinical Practice ◽

Cross Sectional ◽

Multicenter Observational Study

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Design and rationale of NATURE-HTN: the NAtional Tunisian REgistry of HyperTensioN (Preprint)

10.2196/preprints.21878 ◽

2020 ◽

Author(s):

Leila Abid ◽

Salem Abdesselem ◽

Rania Hammami ◽

Hedi Ben Slima ◽

Khaled Sayahi ◽

...

Keyword(s):

Clinical Practice ◽

Adverse Events ◽

Medical Treatment ◽

Daily Clinical Practice ◽

Web Interface ◽

Adherence To Treatment ◽

Cross Sectional ◽

Public And Private ◽

Hypertensive Patients ◽

Therapeutic Environment

BACKGROUND The present study was designed to evaluate the care of hypertensive patients in daily clinical practice in public and private centers in all Tunisian regions. It will allow us to have an overview of the Tunisian hypertensive patient in order to optimize treatment and to know the degree of adherence of practitioners to international recommendations in the care of the hypertension in Tunisia. OBJECTIVE he present study was designed to evaluate the care of hypertensive patients in daily clinical practice in public and private centers in all Tunisian regions. METHODS National, observational, cross-sectional, and multicenter study that will include patients older than 18 years with hypertension for duration of 4 weeks, following up in public and private centers and after signing a consent form. The study will exclude patients undergoing dialysis. The parameters that will be evaluated include demographic and anthropometric data, lifestyle habits, BP levels, lipid profile, treatment and adherence to treatment. The data are collected via the DACIMA Clinical Suite® web interface. RESULTS At the end of the study, we will find the demographic and anthropometric characteristics of the patients, their past medical history, clinical features and their paraclinical exploratory characteristics (biology, EKG and / or holter blood pressure, transthoracic echocardiography (TTE),). We will provide a description of the therapeutic environment and of adverse events occurring during medical treatment and recommendations. CONCLUSIONS We will provide a description of the therapeutic environment and of adverse events occurring during medical treatment and recommendations. CLINICALTRIAL ClinicalTrials.gov Identifier: NCT04013503.

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Physicians’ Perceptions of Their Patients’ Attitude and Knowledge of Long-Term Oral Anticoagulant Therapy in Bulgaria

Medicina ◽

10.3390/medicina55070313 ◽

2019 ◽

Vol 55 (7) ◽

pp. 313 ◽

Cited By ~ 1

Author(s):

Runev ◽

Potpara ◽

Naydenov ◽

Vladimirova ◽

Georgieva ◽

...

Keyword(s):

Clinical Practice ◽

Elective Surgery ◽

Oral Anticoagulant Therapy ◽

Cross Sectional Study ◽

Continuous Medical Education ◽

Influential Factors ◽

Daily Clinical Practice ◽

Final Decision ◽

Cross Sectional

Background and Objectives: Oral anticoagulation (OAC) is widely used in daily clinical practice worldwide for various indications. We aimed to explore the perception of Bulgarian clinicians about their patients’ attitude and knowledge of long-term OAC, prescribed for atrial fibrillation (AF) and/or known deep venous thrombosis (DVT)/pulmonary embolism (PE). Materials and Methods: We performed a cross-sectional study that involved 226 specialists: 187 (82.7%) cardiologists, 23 (10.2%) neurologists, and 16 (7.1%) vascular surgeons. They filled in a questionnaire, specially designed for our study, answering various questions regarding OAC treatment in their daily clinical practice. Results: The mean prescription rate of OACs in AF patients was 80.3% and in DVT/PE—88.6%. One hundred and eighty-seven (82.7%) of the participants stated they see their patients on OAC at least once per month. According to more than one-third of the inquired clinicians, the patients did not understand well enough the provided information concerning net clinical benefit of OAC treatment. About 68% of the clinicians declared that their patients would prefer a “mutual” approach, discussing with the physician the OAC options and taking together the final decision, whereas according to 43 (19.0%), the patients preferred the physician to take a decision for them. Patients’ OAC treatment had been interrupted at least once within the last year due to a physician’s decision by 178 (78.8%) of the participants and the most common reason was elective surgery. The most influential factors for a patient’s choice of OAC were the need of a specific diet to be kept, intake frequency, and possible adverse reactions. Conclusions: Our results suggest that a clinician’s continuous medical education, shared decision-making, and appropriate local strategies for improved awareness of AF/DVT/PE patients are key factors for improvement of OAC management.

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Prescribing for Nausea in Palliative Care: A Cross-Sectional National Survey of Australian Palliative Medicine Doctors

Journal of Palliative Medicine ◽

10.1089/jpm.2013.0610 ◽

2014 ◽

Vol 17 (9) ◽

pp. 1032-1036 ◽

Cited By ~ 3

Author(s):

Timothy H.M. To ◽

Meera Agar ◽

Patsy Yates ◽

David C. Currow

Keyword(s):

Palliative Care ◽

National Survey ◽

Palliative Medicine ◽

Cross Sectional

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The Problem of Multidrug Resistance Bacterial Strains in Daily Clinical Practice in Dealing with Typhoid Fever in Mid-Euphrates Region of Iraq: A Cross Sectional Study

Indian Journal of Forensic Medicine & Toxicology ◽

10.37506/ijfmt.v14i1.120 ◽

2020 ◽

Keyword(s):

Clinical Practice ◽

Multidrug Resistance ◽

Typhoid Fever ◽

Cross Sectional Study ◽

Daily Clinical Practice ◽

Sectional Study ◽

Bacterial Strains ◽

Cross Sectional

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Studies on Serum Creatinine and Creatinine Clearance in Hypertensive Patients

Journal of Bangladesh Society of Physiologist ◽

10.3329/jbsp.v1i0.716 ◽

1970 ◽

Vol 1 ◽

pp. 19-26

Author(s):

D Sarkar ◽

SA Latif ◽

J Aich ◽

MM Uddin

Keyword(s):

Clinical Practice ◽

Serum Creatinine ◽

Creatinine Clearance ◽

Daily Clinical Practice ◽

College Hospital ◽

Cross Sectional ◽

Hypertensive Patients ◽

Mean Values ◽

Medical College ◽

Routine Monitoring

Objectives: To assess the serum creatinine and creatinine clearance values in hypertensive patients for providing information to the health-policy planners, clinical practitioners about the importance of routine monitoring of serum creatinine and creatinine clearance in hypertensive patients for prevention of ESRD and other consequences to combat morbidity and mortality and to reinforce the need to consider these parameters in daily clinical practice. Study design: It was a cross-sectional study. Setting: The study was conducted at Department of Physiology and Biochemistry of Mymensingh Medical College, Medicine Unit of Mymensingh Medical College Hospital. Study period: The period of the study was January 2005 to December 2005. Participants: A total number of seventy subjects were included in this study. Out of 70 subjects, 40 (forty) were hypertensive patients and 30 (thirty) were normotensive & healthy controls. Intervention: The subjects were selected on the basis of history and clinical examination. Convenient sampling technique was applied. During visit the available hypertensive patients and controls (normotensive & healthy) those who were present were selected. Having received their written consent they were interviewed & examined by prepared personal data sheet and sample of blood (after overnight fasting) was drawn for biochemical examination. Main outcome measure: Mean values of serum creatinine and creatinine clearance. Result: Serum creatinine was greater in hypertensive than those of normotensive. Creatinine clearance was less in hypertensive than those of normotensive. Serum creatinine & creatinine clearance in between males hypertensive & control shows that CrCl were statistically significant but not the serum creatinine. In females of hypertensive & control shows no differences in case of SCr & CrCl. Among 40 hypertensive the number of Getting treatment - regular & Getting treatment-irregular was 14 (35%) & 26 (65%) respectively. Similarly in patients suffering less than 5 yrs and suffering 5 yrs & above the differences are also not statistically significant. Conclusion: The observations of this study revealed that most of the hypertensive patients were taking treatment irregularly and there was significant alteration of biochemical parameters in hypertensive patients. Therefore, for routine monitoring of hypertensive patients to prevent the end stage renal disease (ESRD) and other consequences, the reinforcement of the investigations of these parameters may be recommended in daily clinical practice. Key Words: Hypertension, creatinine, creatinine clearance, Cockcroft-Gault formula J Bangladesh Soc Physiol. 2006 Dec;(1):19-26.

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