Association between plasma copper levels and first stroke: a community-based nested case–control study

2021 ◽  
pp. 1-10
Author(s):  
Lihua Hu ◽  
Chonglei Bi ◽  
Tengfei Lin ◽  
Lishun Liu ◽  
Yun Song ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Community Based ◽  
Plasma Copper ◽  
Nested Case Control ◽  
Control Study

scholarly journals Suicide by people in a community justice pathway: Population-based nested case–control study

2015 ◽  
Vol 207 (2) ◽  
pp. 175-176 ◽  
Author(s):  
Carlene King ◽  
Jane Senior ◽  
Roger T. Webb ◽  
Tim Millar ◽  
Mary Piper ◽  
...  
Keyword(s):  
Suicide Risk ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Elevated Risk ◽  
Sexual Offences ◽  
Community Based ◽  
Community Justice ◽  
Nested Case Control ◽  
Control Study

SummaryThe elevated risk of suicide in prison and after release is a well-recognised and serious problem. Despite this, evidence concerning community-based offenders' suicide risk is sparse. We conducted a population-based nested case–control study of all people in a community justice pathway in England and Wales. Our data show 13% of general population suicides were in community justice pathways before death. Suicide risks were highest among individuals receiving police cautions, and those having recent, or impending prosecution for sexual offences. Findings have implications for the training and practice of clinicians identifying and assessing suicidality, and offering support to those at elevated risk.

scholarly journals Determinants of skilled attendance for delivery in Northwest Ethiopia: a community based nested case control study

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Zelalem Birhanu Mengesha ◽  
Gashaw Andargie Biks ◽  
Tadesse Awoke Ayele ◽  
Gizachew Assefa Tessema ◽  
Digsu Negesse Koye
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Northwest Ethiopia ◽  
Community Based ◽  
Skilled Attendance ◽  
Nested Case Control ◽  
Control Study

scholarly journals Dyslipidemia Modified the Association Between Serum Uric Acid and First Hemorrhagic Stroke Among Chinese Population : A Community Based Nested Case-control Study

2020 ◽  
Author(s):  
Hui Liu ◽  
Chonglei Bi ◽  
Tengfei Lin ◽  
Lishun Liu ◽  
Chengzhang Liu ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Hemorrhagic Stroke ◽  
Case Control Study ◽  
Case Control ◽  
Community Based ◽  
Increased Risk ◽  
Nested Case Control ◽  
And Control ◽  
Control Study

Abstract Background: Previous studies have shown that serum uric acid (SUA) and dyslipidemia are risk factors for stroke. However, it is not clear that whether dyslipidemia could modify the association between SUA and hemorrhagic stroke.Methods: We conducted a nested case-control study from “H-type Hypertension and Stroke Prevention and Control Project (HSPCP)” in China. A total of 355 first hemorrhagic stroke cases and 355 controls matched for age (± 1 years), sex and study site were included in the final data analysis. Logistic regression analysis were performed to assess the association between SUA and first hemorrhagic stroke.Results: In matched analysis, the risk of hemorrhagic stroke was associated with the increased SUA levels (OR:1.13, 95% CI:0.98 to 1.30). However, multiple regression analyses showed that per 1 mg/dL in SUA was associated with a 16% decreased risk of hemorrhagic stroke among participants without dyslipidemia and associated with a 28% increased risk of hemorrhagic stroke among dyslipidemia participants [without dyslipidemia: odds ratio (OR) = 0.84, 95% CI 0.65 to 1.09, with dyslipidemia: OR = 1.28, 95% CI 1.10 to 1.48; P Interaction ＜0.001]. The results of the subgroup analysis were consistent with the main results.Conclusions: Elevated SUA was associated with increased risk of hemorrhagic stroke especially among participants with dyslipidemia. These findings suggest that we need to focus on SUA levels especially among participants with dyslipidemia.

scholarly journals Important risk factors of mortality among children aged 1-59 months in rural areas of Shahroud, Iran: A community-based nested case-control study

2012 ◽  
Vol 3 (12) ◽  
pp. 875 ◽  
Author(s):  
Reza Chaman ◽  
Ali Alami ◽  
MohammadHassan Emamian ◽  
KouroshHolakouie Naieni ◽  
Majid Mirmohammadkhani ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rural Areas ◽  
Case Control Study ◽  
Case Control ◽  
Community Based ◽  
Nested Case Control ◽  
Control Study

scholarly journals Serum α-linolenic and other ω-3 fatty acids, and risk of disabling dementia: Community-based nested case–control study

2017 ◽  
Vol 36 (3) ◽  
pp. 793-797 ◽  
Author(s):  
Kazumasa Yamagishi ◽  
Ai Ikeda ◽  
Choy-Lye Chei ◽  
Hiroyuki Noda ◽  
Mitsumasa Umesawa ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Case Control Study ◽  
Case Control ◽  
Community Based ◽  
Nested Case Control ◽  
Control Study

scholarly journals Plasma copper and the risk of first stroke in hypertensive patients: a nested case-control study

2019 ◽  
Vol 110 (1) ◽  
pp. 212-220 ◽  
Author(s):  
Jingping Zhang ◽  
Jingjing Cao ◽  
Hao Zhang ◽  
Chongfei Jiang ◽  
Tengfei Lin ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Ischemic Stroke ◽  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
Significant Positive Association ◽  
Hypertensive Patients ◽  
Plasma Copper ◽  
Nested Case Control ◽  
Control Study

ABSTRACT Background Previous studies indicated that trace elements may play an important role in cardiovascular diseases. However, data concerning the association between blood copper and the risk of stroke are limited. Objective The aim of this study was to evaluate the association between plasma copper and the risk of first stroke, and examine any possible effect modifiers in hypertensive patients. Methods We conducted a nested case-control study, using data from the China Stroke Primary Prevention Trial. Hypertension is defined as systolic blood pressure ≥ 140 mm Hg or diastolic blood pressure ≥ 90 mm Hg, or taking antihypertensive medication. A total of 618 first stroke cases and 618 controls matched for age, sex, treatment group, and study site were included in this study. The crude and adjusted risks of first stroke were estimated by ORs and 95% CIs using conditional logistic regression, without or with adjusting for pertinent covariates, respectively. Results There were significant positive associations of plasma copper with risk of first stroke (per SD increment—OR: 1.20; 95% CI: 1.03, 1.39) and first ischemic stroke (OR: 1.26; 95% CI: 1.07, 1.50). When plasma copper was categorized in quartiles, significantly higher risks of first stroke (OR: 1.72; 95% CI: 1.12, 2.65) and first ischemic stroke (OR: 1.91; 95% CI: 1.18, 3.11) were found in participants in quartile 4 (≥ 117.0 μg/dL) than in those in quartile 1 (< 91.2 μg/dL). Furthermore, the plasma copper–first stroke association was significantly stronger in participants with higher BMI (< 25.0 compared with ≥ 25.0 kg/m2, P-interaction = 0.024). However, there was no significant association between plasma copper and first hemorrhagic stroke. Conclusions In Chinese hypertensive patients, there was a significant positive association between baseline plasma copper and the risk of first stroke, especially among those with higher BMI. This trial was registered at clinicaltrials.gov as NCT00794885.

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