Bone health in patients with epilepsy: A community-based pilot nested case–control study

AbstractPeople with epilepsy (PWE) have an increased suicide prevalence. This study aimed to identify the risk factors for suicidal tendency among PWE in West China. A nested case–control study was designed in a cohort of patients with epilepsy (n = 2087). In total, 28 variates were calculated. In the univariate analysis, unemployment, low income, seizure frequency, seizure-free time, infectious or structural etiology, levetiracetam or phenobarbital use, anxiety, depression, and stigma were associated with suicidal tendency. A multivariate analysis indicated that unemployment (odds ratio [OR] 5.74, 95% confidence interval [CI] 2.13–15.48), levetiracetam use (OR 2.80, 95%CI 1.11–7.05), depression (C-NDDI-E score ≥ 13; OR 3.21, 95%CI 1.26–8.21), and stigma (SSCI score ≥ 16; OR 6.67, 95%CI 1.80–24.69) were independently associated with suicidal tendency. Conditional inference tree analysis indicated that SSCI and C-NDDI-E scores could effectively identify patients with suicidal tendency. Thus, this study suggests that unemployment, levetiracetam use, depression, and stigma are independent risk factors for suicidal tendency in PWE in China.

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Association between plasma copper levels and first stroke: a community-based nested case–control study

Nutritional Neuroscience ◽

10.1080/1028415x.2021.1875299 ◽

2021 ◽

pp. 1-10

Author(s):

Lihua Hu ◽

Chonglei Bi ◽

Tengfei Lin ◽

Lishun Liu ◽

Yun Song ◽

...

Keyword(s):

Case Control Study ◽

Case Control ◽

Community Based ◽

Plasma Copper ◽

Nested Case Control ◽

Control Study

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Suicide by people in a community justice pathway: Population-based nested case–control study

The British Journal of Psychiatry ◽

10.1192/bjp.bp.114.154831 ◽

2015 ◽

Vol 207 (2) ◽

pp. 175-176 ◽

Cited By ~ 13

Author(s):

Carlene King ◽

Jane Senior ◽

Roger T. Webb ◽

Tim Millar ◽

Mary Piper ◽

...

Keyword(s):

Suicide Risk ◽

Case Control Study ◽

Population Based ◽

Case Control ◽

Elevated Risk ◽

Sexual Offences ◽

Community Based ◽

Community Justice ◽

Nested Case Control ◽

Control Study

SummaryThe elevated risk of suicide in prison and after release is a well-recognised and serious problem. Despite this, evidence concerning community-based offenders' suicide risk is sparse. We conducted a population-based nested case–control study of all people in a community justice pathway in England and Wales. Our data show 13% of general population suicides were in community justice pathways before death. Suicide risks were highest among individuals receiving police cautions, and those having recent, or impending prosecution for sexual offences. Findings have implications for the training and practice of clinicians identifying and assessing suicidality, and offering support to those at elevated risk.

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Determinants of perinatal mortality among cohorts of pregnant women in three districts of North Showa zone, Oromia Region, Ethiopia: Community based nested case control study

BMC Public Health ◽

10.1186/s12889-018-5757-2 ◽

2018 ◽

Vol 18 (1) ◽

Cited By ~ 8

Author(s):

Elias Merdassa Roro ◽

Mitike Molla Sisay ◽

Lynn M. Sibley

Keyword(s):

Pregnant Women ◽

Perinatal Mortality ◽

Case Control Study ◽

Case Control ◽

Community Based ◽

Nested Case Control ◽

Control Study

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Determinants of skilled attendance for delivery in Northwest Ethiopia: a community based nested case control study

BMC Public Health ◽

10.1186/1471-2458-13-130 ◽

2013 ◽

Vol 13 (1) ◽

Cited By ~ 36

Author(s):

Zelalem Birhanu Mengesha ◽

Gashaw Andargie Biks ◽

Tadesse Awoke Ayele ◽

Gizachew Assefa Tessema ◽

Digsu Negesse Koye

Keyword(s):

Case Control Study ◽

Case Control ◽

Northwest Ethiopia ◽

Community Based ◽

Skilled Attendance ◽

Nested Case Control ◽

Control Study

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Dyslipidemia Modified the Association Between Serum Uric Acid and First Hemorrhagic Stroke Among Chinese Population : A Community Based Nested Case-control Study

10.21203/rs.3.rs-124307/v1 ◽

2020 ◽

Author(s):

Hui Liu ◽

Chonglei Bi ◽

Tengfei Lin ◽

Lishun Liu ◽

Chengzhang Liu ◽

...

Keyword(s):

Uric Acid ◽

Serum Uric Acid ◽

Hemorrhagic Stroke ◽

Case Control Study ◽

Case Control ◽

Community Based ◽

Increased Risk ◽

Nested Case Control ◽

And Control ◽

Control Study

Abstract Background: Previous studies have shown that serum uric acid (SUA) and dyslipidemia are risk factors for stroke. However, it is not clear that whether dyslipidemia could modify the association between SUA and hemorrhagic stroke.Methods: We conducted a nested case-control study from “H-type Hypertension and Stroke Prevention and Control Project (HSPCP)” in China. A total of 355 first hemorrhagic stroke cases and 355 controls matched for age (± 1 years), sex and study site were included in the final data analysis. Logistic regression analysis were performed to assess the association between SUA and first hemorrhagic stroke.Results: In matched analysis, the risk of hemorrhagic stroke was associated with the increased SUA levels (OR:1.13, 95% CI:0.98 to 1.30). However, multiple regression analyses showed that per 1 mg/dL in SUA was associated with a 16% decreased risk of hemorrhagic stroke among participants without dyslipidemia and associated with a 28% increased risk of hemorrhagic stroke among dyslipidemia participants [without dyslipidemia: odds ratio (OR) = 0.84, 95% CI 0.65 to 1.09, with dyslipidemia: OR = 1.28, 95% CI 1.10 to 1.48; P Interaction ＜0.001]. The results of the subgroup analysis were consistent with the main results.Conclusions: Elevated SUA was associated with increased risk of hemorrhagic stroke especially among participants with dyslipidemia. These findings suggest that we need to focus on SUA levels especially among participants with dyslipidemia.

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