Conjugated linoleic acid (CLA) has a potential role in the prevention of cancer tumors of the skin, breast, stomach and intestine. CLA also has the ability to prevent cardiovascular disease, atherosclerotic disease, diabetes, regulation of immune responses and change in body composition by reducing body fat. Fats that originated from the ruminants are the main sources of CLA. But poultry products are contain traces of these fatty acids. Fatty acids content in monogastric diets did not change after digestion and absorption, compared with ruminants. So use of synthetic CLA or its precursors, can increase the synthesis and save of this fatty acid in poultry products. After absorption, the CLA or its resources, are stored in phospholipids of call membrane, fatty tissue and eggs. Therefore attempts to enrich poultry production via CLA as an appropriate method for improving human nutrition by organic sources, will cause the useful results.DOI: http://dx.doi.org/10.3126/ijls.v9i4.12676