Depressive symptoms are associated with immunological failure among HIV-positive patients in Vietnam

Abstract Objective: To understand the relationship between drug use, food insecurity (FI), and mental health among men who have sex with men (MSM). Design: Cohort study (2014-2019) with at least one follow-up. Setting: Visits at 6-month intervals included self-assessment for FI and depressive symptoms. Urine testing results confirmed drug use. Factors associated with FI were assessed using multiple logistic regression with random effects for repeated measures. General structural equation modeling tested whether FI mediates the relationship between drug use and depressive symptoms. Participants: Data were from HIV-positive and high-risk HIV negative MSM in Los Angeles, CA (n=431; 1,192 visits). Results: At baseline, FI was reported by 50.8% of participants, depressive symptoms in 36.7%, and 52.7% of urine screening tests were positive for drugs (i.e., marijuana, opioids, methamphetamine, cocaine, ecstasy). A positive drug test was associated with a 96% increase in the odds of being food insecure (95% CI: 1.26-3.07). Compared to those with high food security, individuals with very low food security have a nearly 7-fold increase in the odds of reporting depressive symptoms (95% CI: 3.71-11.92). Findings showed 14.9% of the association between drug use (exposure) and depressive symptoms (outcome) can be explained by FI (mediator). Conclusion: The prevalence of FI among this cohort of HIV-positive and high-risk HIV-negative MSM was high; the association between drug use and depressive symptoms was partially mediated by FI. Findings suggest that enhancing access to food and nutrition may improve mood in the context of drug use, especially among MSM at risk for HIV-transmission.

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A path model of the effects of spirituality on depressive symptoms and 24-hurinary-free cortisol in HIV-positive persons

Journal of Psychosomatic Research ◽

10.1016/j.jpsychores.2006.04.005 ◽

2006 ◽

Vol 61 (1) ◽

pp. 51-58 ◽

Cited By ~ 66

Author(s):

Adam W. Carrico ◽

Gail Ironson ◽

Michael H. Antoni ◽

Suzanne C. Lechner ◽

Ron E. Durán ◽

...

Keyword(s):

Depressive Symptoms ◽

Path Model ◽

Hiv Positive ◽

Free Cortisol

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Lack of Medical Support in HIV Infection and Unstable Mood States

Psychological Reports ◽

10.2466/pr0.1997.81.2.635 ◽

1997 ◽

Vol 81 (2) ◽

pp. 635-639

Author(s):

Motoko Hayashi ◽

Isao Fukunishi

Keyword(s):

Social Support ◽

Depressive Symptoms ◽

Major Depression ◽

Hiv Infection ◽

Mood Disorders ◽

Early Stage ◽

Mood States ◽

Hiv Positive ◽

Medical Support ◽

Hiv Patients

This study examined what kinds of social support are related to mood states in a sample of 50 HIV-positive patients without AIDS (46 men and 4 women; M age 36.5 yr., SD = 9.8). In the early stage of HIV infection, HIV patients without AIDS may be prone to depressive symptoms although none of these HIV-positive patients' symptoms fulfilled the DSM-III-R Mood Disorders including Major Depression. The depressive symptoms were not significantly related to lack of ordinary social support such as friends and family but were significantly associated with dissatisfaction with HIV/AIDS-related medical support

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Subtypes of depressive symptoms and inflammatory biomarkers: An exploratory study on a sample of HIV-positive patients

Brain Behavior and Immunity ◽

10.1016/j.bbi.2016.02.013 ◽

2016 ◽

Vol 56 ◽

pp. 105-113 ◽

Cited By ~ 20

Author(s):

A. Norcini Pala ◽

P. Steca ◽

R. Bagrodia ◽

L. Helpman ◽

V. Colangeli ◽

...

Keyword(s):

Depressive Symptoms ◽

Exploratory Study ◽

Inflammatory Biomarkers ◽

Hiv Positive

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Depressive Symptoms Among HIV Positive Men: Life Stress, Coping, and Social Support

Journal of Applied Biobehavioral Research ◽

10.1111/j.1751-9861.1993.tb00028.x ◽

1993 ◽

Vol 1 (1) ◽

pp. 64-87 ◽

Cited By ~ 12

Author(s):

Thomas L. Patterson* ◽

Shirley J. Semple ◽

Lydia R. Temoshok ◽

J. Hampton Atkinson ◽

J. Allen McCutchan ◽

...

Keyword(s):

Social Support ◽

Depressive Symptoms ◽

Life Stress ◽

Hiv Positive ◽

Stress Coping ◽

Hiv Positive Men

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Risky Alcohol Consumption and Associated Health Behaviour Among HIV-Positive and HIV-Negative Patients in a UK Sexual Health and HIV Clinic: A Cross-Sectional Questionnaire Study

AIDS and Behavior ◽

10.1007/s10461-019-02714-2 ◽

2019 ◽

Vol 24 (6) ◽

pp. 1717-1726 ◽

Cited By ~ 1

Author(s):

Emmi Suonpera ◽

Rebecca Matthews ◽

Ana Milinkovic ◽

Alejandro Arenas-Pinto

Keyword(s):

Depressive Symptoms ◽

Alcohol Consumption ◽

Drug Use ◽

Questionnaire Study ◽

Hiv Positive ◽

Cross Sectional ◽

Problematic Drug ◽

Risky Alcohol ◽

Risky Alcohol Consumption ◽

Hiv Negative

Abstract Alcohol misuse has been associated with negative consequences among HIV-positive patients. Data on real prevalence of risky alcohol consumption among the HIV-positive population in the UK are lacking. A cross-sectional questionnaire study using standardised validated instruments among HIV-positive (n = 227) and HIV-negative (n = 69) patients was performed. The prevalence of risky alcohol consumption (AUDIT) and associations with depressive symptoms (PHQ-9), problematic drug use (DUDIT), adherence to ART (CASE Adherence Index), sexual behaviour and demographic characteristics were assessed among both patient groups independently. A quarter (25.1%) of HIV-positive patients and 36.1% of HIV-negative patients reported risky alcohol consumption (AUDIT-score ≥ 8). In the multivariable analysis among HIV-positive patients depressive symptoms (p = 0.03) and problematic drug use (p = 0.007) were associated with risky alcohol consumption. Among HIV-negative patients these associations were not present. Risky alcohol consumption among HIV-positive patients is prevalent, and together with depressive symptoms and problematic drug use, may influence HIV-disease progression and patients’ wellbeing.

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