PROTECTIVE EFFECTS OF ANTIOXIDANT SUPPLEMENTATION ON PLASMA LIPID PEROXIDATION IN SMOKERS

2001 ◽  
Vol 63 (8) ◽  
pp. 583-598 ◽  
Author(s):  
Hyung Sik Kim ◽  
Byung Mu Lee
Keyword(s):  
Lipid Peroxidation ◽  
Plasma Lipid ◽  
Protective Effects ◽  
Antioxidant Supplementation ◽  
Plasma Lipid Peroxidation

scholarly journals The protective effects of selenoorganic compounds against peroxynitrite-induced changes in plasma proteins and lipids

2006 ◽  
Vol 11 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Paweł Nowak ◽  
Joanna Saluk-Juszczak ◽  
Beata Olas ◽  
Joanna Kołodziejczyk ◽  
Barbara Wachowicz
Keyword(s):  
Lipid Peroxidation ◽  
Human Plasma ◽  
Plasma Proteins ◽  
Enzyme Inhibitors ◽  
Group Formation ◽  
Plasma Lipid ◽  
Protective Effects ◽  
Induced Changes ◽  
Plasma Lipid Peroxidation

AbstractMany selenoorganic compounds play an important role in biochemical processes and act as antioxidants, enzyme inhibitors or drugs. The effects of a new selenocompound — bis(2-aminophenyl)-diselenide on oxidative/nitrative changes in human plasma proteins induced by peroxynitrite (ONOO−) were studied in vitro and compared with the those of ebselen, a well-known antioxidant. We also studied the role of the tested selenocompounds in peroxynitrite-induced plasma lipid peroxidation. Exposure of the plasma to peroxynitrite (0.1 mM) resulted in an increase in the level of carbonyl groups and nitrotyrosine residues in plasma proteins (estimated using the ELISA method and Western blot analysis). In the presence of different concentrations (0.025–0.1 mM) of the tested selenocompounds, 0.1 mM peroxynitrite caused a distinct decrease in the level of carbonyl group formation and tyrosine nitration in plasma proteins. Moreover, these selenocompounds also inhibited plasma lipid peroxidation induced by ONOO−1 (0.1 mM). The obtained results indicate that in vitro bis(2-aminophenyl)-diselenide and ebselen have very similar protective effects against peroxynitrite-induced oxidative/nitrative damage to human plasma proteins and lipids.

scholarly journals Plasma Lipid Peroxidation as a Marker for Seminal Oxidative Stress in Stallion

2019 ◽  
Vol 11 (6) ◽  
pp. 401
Author(s):  
Patricia Wolkmer ◽  
Andressa M. G. Stumm ◽  
Luiz F. K. Borges ◽  
Eduarda P. T. Ferreira ◽  
Bruna Favaretto ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Seminal Plasma ◽  
Plasma Lipid ◽  
Thiobarbituric Acid ◽  
Thiobarbituric Acid Reactive Substances ◽  
Semen Collection ◽  
Semen Storage ◽  
Plasma Lipid Peroxidation ◽  
Antioxidant Enzyme Catalase

This experiment aims to evaluate the correlation between lipid peroxidation levels in serum and seminal plasma in equines. Also, it investigates the lipid peroxidation in extended semen samples and its effects and sperm motility during a 72 hr refrigeration period. Blood and semen were collected from fertile Crioulo stallions. Serum and seminal plasma lipid peroxidation levels were analyzed by thiobarbituric acid reactive substances (TBARS) immediately after semen collection. After addition of extender (hour = 0), diluted semen was refrigerated and stored at 5 °C. Semen analyses, TBARS and catalase activity were performed in extended semen at 0, 24, 48, and 72 hours. We noted that levels of plasma lipid peroxidation can be used as an indicative of seminal oxidative stress. Also, lipid peroxidation does not increase substantially during semen storage. Lipid peroxidation and the antioxidant enzyme catalase do not seem to be the major cause of loss and motility and consequently reduction in fertility in stallion semen during storage for 72 h at 5 °C.

Plasma lipid peroxidation biomarkers for early and non-invasive Alzheimer Disease detection

2018 ◽  
Vol 124 ◽  
pp. 388-394 ◽  
Author(s):  
Carmen Peña-Bautista ◽  
Claire Vigor ◽  
Jean-Marie Galano ◽  
Camille Oger ◽  
Thierry Durand ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Alzheimer Disease ◽  
Plasma Lipid ◽  
Disease Detection ◽  
Non Invasive ◽  
Plasma Lipid Peroxidation

Lactobacilli modulated AMPK activity and prevented telomere shortening in ageing rats

2019 ◽  
Vol 10 (8) ◽  
pp. 883-892
Author(s):  
L.C. Lew ◽  
Y.Y. Hor ◽  
M.H. Jaafar ◽  
A.S.Y. Lau ◽  
J.S. Ong ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Rat Model ◽  
High Fat Diet ◽  
Lactobacillus Reuteri ◽  
Plasma Lipid ◽  
Dependent Manner ◽  
Sprague Dawley ◽  
High Fat ◽  
Age Related ◽  
Plasma Lipid Peroxidation

This study aimed to evaluate the anti-ageing effects of different strains of lactobacilli putative probiotics on an ageing rat model as induced by D-galactose and a high fat diet. Male Sprague-Dawley rats were fed with high fat diet (54% kcal fat) and injected with D-galactose daily for 12 weeks to induce ageing. The effects of putative probiotic strains on age-related impairment such as telomere length, plasma lipid peroxidation, hepatic 5’adenosine monophosphate-activated protein kinase (AMPK) expression, as well as endurance performance were evaluated. Administration of statin, Lactobacillus plantarum DR7 (LP-DR7), Lactobacillus fermentum DR9 (LF-DR9), and Lactobacillus reuteri 8513d (LR-8513d) significantly reduced the shortening of telomere and increased the expression of AMPK subunit-α1 (P<0.05). Plasma lipid peroxidation was lower (P<0.05) in groups administered with statin and LF-DR9 as compared to the control. AMPK subunit-α2 was elevated in rats administered with LP-DR7 as compared to the control (P<0.05). Using an in vivo ageing rat model, the current study has illustrated the potentials of lactobacilli putative probiotics in alleviation of age-related impairment in a strain-dependent manner.

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