Perceptions of Human Papillomavirus (HPV) infection and acceptability of HPV vaccine among men attending a sexual health clinic differ according to sexual orientation

The human papillomavirus (HPV) vaccine is a key intervention in the prevention of HPV infection and associated cancers. This review emphasizes the importance of understanding what influences decision-making about this vaccine. Guided by the work of Whittemore and Knafl, and Pluye and Hong, we identified 25 studies, from which four prominent themes emerged: fear and risk, pain, parental involvement, and involvement of others. Fear of cervical cancer was a strong motivation to receive the vaccine, and the extent of parental involvement also had an impact on decision-making. Recommendations to receive the vaccine by health-care providers were also an important influence. School nurses are fundamental to the promotion and delivery of the HPV vaccine and should stress the significant role that it plays in the prevention of cancer. Additionally, school nurses should ensure that discussions about HPV infection and vaccine include parents where appropriate and should distinctly recommend vaccination to those eligible.

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High Human Papillomavirus Vaccine Acceptability and Cost-Effectiveness of the Chinese 2-Valent Vaccine Among Men Who Have Sex With Men: A Cross-Sectional Study in Shenyang, China

Frontiers in Medicine ◽

10.3389/fmed.2021.763564 ◽

2021 ◽

Vol 8 ◽

Author(s):

Ze-Hao Ye ◽

Zhao-Zhen Liu ◽

Si-Tong Cui ◽

Zhen-Xing Chu ◽

Yong-Jun Jiang ◽

...

Keyword(s):

Human Papillomavirus ◽

Cost Effectiveness ◽

Hpv Vaccine ◽

Online Survey ◽

Cost Effective ◽

Hpv Infection ◽

Human Papillomavirus Vaccine ◽

Vaccine Acceptability ◽

Cross Sectional ◽

Sex With Men

Background: Despite the insupportable burden caused by the human papillomavirus (HPV) and high vaccine acceptability, vaccination programs are not currently available for men who have sex with men (MSM). We aimed to assess HPV infection by examining the willingness for vaccination among MSM and cost-effectiveness of the Chinese 2-valent HPV vaccine.Methods: We recruited MSM in Shenyang, China between July and December 2020 to conduct anal HPV testing and an online survey regarding HPV-related knowledge and vaccine acceptability. We performed a cost-effectiveness analysis to evaluate the incremental cost-effectiveness ratios (ICERs) of the Chinese 2-valent HPV vaccine.Results: A total of 234 participants completed the online survey; of those, 203 were successfully tested for HPV. The median age was 30 years [interquartile range (IQR): 23–38 years]. Most participants had at least undergraduate education (136/234, 58.1%). The acceptability rate for the free HPV vaccine was 57.7% (135/234). The prevalence of HPV types 16 and 18 was 14.9% (18/121) and 26.8% (22/82) in the willing and unwilling to vaccinate groups, respectively (P > 0.05). The prevalence of high-risk HPV among participants aged <30 and ≥50 years was 48.6 and 38.9%, respectively. Using the Chinese per capita gross domestic product (GDP) as a threshold, the Chinese 2-valent HPV vaccine would be a “very cost-effective” strategy, with an ICER value of USD 4,411. This evidence showed that the Chinese 2-valent HPV vaccine was more cost-effective than other imported vaccines.Conclusions: Targeted strategies should be utilized in MSM with different rates of vaccine acceptability. A pilot HPV vaccination program based on the Chinese 2-valent HPV vaccine for MSM is urgently warranted to reduce the burden of HPV and anal cancer.

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Men who have sex with men who do not access sexual health clinics nor disclose sexual orientation are unlikely to receive the HPV vaccine in the UK

Vaccine ◽

10.1016/j.vaccine.2018.06.075 ◽

2018 ◽

Vol 36 (33) ◽

pp. 5065-5070 ◽

Cited By ~ 6

Author(s):

Tom Nadarzynski ◽

Helen Smith ◽

Daniel Richardson ◽

Stephen Bremner ◽

Carrie Llewellyn

Keyword(s):

Sexual Orientation ◽

Sexual Health ◽

Hpv Vaccine ◽

Health Clinics ◽

Sex With Men ◽

Sexual Health Clinics ◽

The Uk ◽

To Receive

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Human papillomavirus (HPV) vaccine acceptance and perceived effectiveness, and HPV infection concern among young New Zealand university students

Sexual Health ◽

10.1071/sh10005 ◽

2010 ◽

Vol 7 (3) ◽

pp. 394 ◽

Cited By ~ 9

Author(s):

Carol Chelimo ◽

Trecia A. Wouldes ◽

Linda D. Cameron

Keyword(s):

Human Papillomavirus ◽

Undergraduate Students ◽

Hpv Vaccine ◽

Hpv Vaccination ◽

Hpv Infection ◽

Infection Risk ◽

Vaccine Acceptance ◽

Sexually Transmitted ◽

Behavioural Characteristics

Two-hundred undergraduate students completed an anonymous questionnaire after viewing a human papillomavirus (HPV) vaccine television commercial. Eight-four percent of participants would accept a free HPV vaccine, whereas 47% were unconcerned about future personal HPV infection risk. Males were less likely to accept a free HPV vaccine and to be concerned about future personal HPV infection risk. Perceived HPV vaccine effectiveness was significantly greater among participants who had previously heard of the vaccine and who knew that HPV is sexually transmitted. More education on the role of sexual behavioural characteristics of both males and females in HPV transmission is necessary to promote awareness and concern of personal HPV infection risk and acceptance of HPV vaccination.

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Disparities in human papillomavirus (HPV) vaccine initiation and completion based on sexual orientation among women in the United States

Human Vaccines & Immunotherapeutics ◽

10.1080/21645515.2020.1778407 ◽

2020 ◽

pp. 1-6

Author(s):

Eric Adjei Boakye ◽

Nosayaba Osazuwa-Peters ◽

Julia López ◽

Vy T. Pham ◽

Betelihem B. Tobo ◽

...

Keyword(s):

United States ◽

Human Papillomavirus ◽

Sexual Orientation ◽

Hpv Vaccine ◽

The United States ◽

Vaccine Initiation

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Prevalence of oral human papillomavirus in men attending an Italian sexual health clinic

Sexual Health ◽

10.1071/sh16155 ◽

2016 ◽

Vol 13 (6) ◽

pp. 597 ◽

Cited By ~ 4

Author(s):

Francesco Drago ◽

Astrid Herzum ◽

Giulia Ciccarese ◽

Roberto Bandelloni

Keyword(s):

Human Papillomavirus ◽

Hpv Infection ◽

Health Clinic ◽

High Risk Population ◽

Hpv Dna ◽

Hpv Prevalence ◽

Sexually Transmissible Infections ◽

High Prevalence ◽

Oral Hpv ◽

Sex With Men

A high-risk population, formed by 79 consecutive male attendees of our sexually transmissible infections clinic, and who did not have any overt signs of human papillomavirus (HPV) infection, were examined. Oral HPV prevalence (37%) was much higher than previously reported. Periurethral HPV-DNA was found in 49% of the patients and anal HPV-DNA was found in 43% of the patients. Considering the high prevalence of oral HPV obtained in the current study, it is important to further investigate the burden of oral HPV, not only in men who have sex with men, but also in heterosexual men and in women.

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Review of Evidence and Recommendation for Human Papillomavirus (HPV) Vaccination of Canadian Males Over the Age of 26 Years

Journal of Cutaneous Medicine and Surgery ◽

10.1177/1203475420911635 ◽

2020 ◽

Vol 24 (3) ◽

pp. 285-291 ◽

Cited By ~ 2

Author(s):

Alex Derstenfeld ◽

Kyle Cullingham ◽

Zhuo Cai Ran ◽

Ivan V. Litvinov

Keyword(s):

Human Papillomavirus ◽

Sexually Transmitted Infection ◽

Hpv Vaccine ◽

Hpv Vaccination ◽

Older Men ◽

Hpv Infection ◽

Transmitted Infection ◽

Vaccination Programs ◽

Sexually Transmitted ◽

Control And Prevention

Human papillomavirus (HPV) remains the most common sexually transmitted infection with a lifetime incidence of over 75%. Based on US data from the Centers for Disease Control and Prevention (CDC), 64% of invasive HPV-associated cancers are attributable to HPV 16 or 18 (65% for females; 63% males) and may be prevented by vaccination with either the quadrivalent or nonavalent HPV vaccine. Public HPV vaccination programs are now the norm for women aged 9-45 years and men aged 9-26 years in Canada. Yet, only recently have guidelines begun to consider vaccination of men older than 26 years of age. There now exist compelling reasons to recommend vaccination against HPV amongst males >26 years of age. Recognizing that the risks posed by HPV infection persist beyond 26 years of age, that the vaccination of men aged 26-45 years with HPV vaccine confers immunogenicity at levels demonstrably efficacious against HPV-related diseases, and that the Food and Drug Administration recently expanded the HPV vaccination to include older men, it is argued that HPV vaccination in men older than 26 years of age should be routinely recommended.

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HPV AND HEAD NECK MALIGNANCIES – ROLE OF VACCINATION

UP STATE JOURNAL OF OTOLARYNGOLOGY AND HEAD AND NECK SURGERY ◽

10.36611/upjohns/18.4 ◽

2018 ◽

Vol VOLUME 6 (VOLUME 6 NUMBER 2 DECEMBER 2018) ◽

pp. 22-26

Author(s):

Sumit Sharma

Keyword(s):

Squamous Cell Carcinoma ◽

Human Papillomavirus ◽

Hpv Vaccine ◽

Hpv Infection ◽

Sexual Contact ◽

Dna Virus ◽

Modes Of Transmission ◽

Male Sex ◽

Head Neck

Human papillomavirus is a DNA virus from the papillomavirus family and it not only causes genital and anal cancers, but also causes a subset of head and neck squamous cell carcinoma. It has both sexual and non sexual modes of transmission, former being predominant. Other factors associates with higher risk of HPV induced carcinogenesis are -- Smoking and HIV-infection, male sex and older age. Vaccines are available to prevent HPV infection and are to be given to boys and girls between 14-26 years of age preferably before first sexual contact, and if you already have an HPV infection, getting the HPV vaccine can’t treat it, but it can protect you from getting other types of HPV infections.

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Oral sex and oral cancer in the context of human papillomavirus infection: lay public understanding

Oncology Reviews ◽

10.4081/oncol.2010.171 ◽

2011 ◽

Vol 4 (3) ◽

pp. 171

Author(s):

Mario A. Brondani ◽

Mario A. Cruz-Cabrera ◽

Cheryle Colombe

Keyword(s):

Human Papillomavirus ◽

Sexual Orientation ◽

Oral Cancer ◽

Small Sample Size ◽

Hpv Infection ◽

Small Sample ◽

Public Understanding ◽

Sexual Practices ◽

Cancer Development ◽

Oral Sex

Human papillomavirus (HPV) is a risk factor for ano-genital and cervical cancers and has been associated with head and neck malignancies in the context of oral sex for the transmission of the virus. However, the level of knowledge that lay people have in terms of HPV transmission through oral sex and oral cancer development remains unknown. A pilot sample of 150 questionnaires was distributed at specific non-profit health organizations in Vancouver, Canada. Questions included perceived risks for oral sex in terms of HPV infection and oral cancer development, and the frequency with which respondents were asked about oral sexual practices by physicians and dentists. Data were analysed statistically by age group (19– 30, 31–50, 50\), gender (male, female), and sexual orientation (queer, straight). 110 questionnaires were returned fully completed. For the transmission of HPV, 58% of the participants believed that oral sex is an activity of no or low risk, whereas 72% considered the same activity to be of no risk for the development of oral cancer. There was no statistical difference between gender and sexual orientation. Participants never discussed related health risks in regard to oral sex with their physicians or dentists. In conclusion, although recent attention has been given to the potential links between HPV infection and oral cancer, such links remain mostly unknown by the public. Physicians and dentists could discuss oral sex practices to raise awareness with their patients. This is a small sample size study and the results should be interpreted with caution.

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