scholarly journals Elimination of congenital rubella: a seroprevalence study of pregnant women and women of childbearing age in Italy

2019 ◽  
Vol 16 (4) ◽  
pp. 895-898 ◽  
Author(s):  
Serena Marchi ◽  
Simonetta Viviani ◽  
Emanuele Montomoli ◽  
Claudia Maria Trombetta
2016 ◽  
Vol 2016 ◽  
pp. 1-8
Author(s):  
Anna Lena Lopez ◽  
Peter Francis N. Raguindin ◽  
Maria Asuncion Silvestre ◽  
Xenia Cathrine J. Fabay ◽  
Ariel B. Vinarao ◽  
...  

Background. As part of regional elimination efforts, rubella-containing vaccines (RCV) have recently been introduced in the Philippines, yet the true burden of rubella and congenital rubella syndrome (CRS) in the country is largely unknown.Objective. To provide baseline information on rubella and CRS prior to routine vaccine introduction in the Philippines.Methods. We conducted a systematic literature review on rubella and CRS in the Philippines, including a cross-sectional study conducted in 2002 among 383 pregnant women attending the obstetric outpatient clinic of the Philippine General Hospital to assess rubella susceptibility of women of childbearing age.Results. 15 locally published and unpublished studies were reviewed. Susceptibility to rubella among women of childbearing age was higher in rural communities. Retrospective reviews revealed congenital heart diseases, cataracts, and hearing impairments to be most common presentations in children of CRS. In the cross-sectional study, 59 (15.4%) of the 383 pregnant women enrolled were seronegative for rubella IgG.Conclusion. Similar to other countries introducing RCV, it was only recently that surveillance for rubella has been established. Previous studies show substantial disabilities due to CRS and a substantial proportion of susceptible women who are at risk for having babies affected with CRS. Establishment of CRS surveillance and enhanced awareness on rubella case detection should be prioritized.


2006 ◽  
Vol 135 (4) ◽  
pp. 555-562 ◽  
Author(s):  
M. C. ROTA ◽  
A. BELLA ◽  
G. GABUTTI ◽  
C. GIAMBI ◽  
A. FILIA ◽  
...  

SUMMARYThe objective of this study is to evaluate how increasing MMR infant vaccination coverage in recent years has modified the epidemiology of rubella in Italy. A cross-sectional population-based seroprevalence study of rubella antibodies was conducted on 3094 sera, in 2004, and results were compared with data obtained by the same method in 1996. The overall proportion of rubella-seropositive individuals was found to be significantly higher in 2004 with respect to 1996 (84·6% vs. 77·4%). However, an increase in seropositivity was observed only in the 1–19 years age groups. Recent increases in childhood MMR vaccination coverage, therefore, have not had an impact on seroprevalence in women of childbearing age, over 5% of whom remain susceptible to rubella. Preconception screening and postpartum vaccination of susceptible women are fundamental if the WHO target of less than one case of congenital rubella syndrome per 100 000 live births is to be attained.


2017 ◽  
Vol 18 (1) ◽  
Author(s):  
K Michael Hambidge ◽  
Nancy F Krebs ◽  
Ana Garcés ◽  
Jamie E Westcott ◽  
Lester Figueroa ◽  
...  

2018 ◽  
Vol 55 (5) ◽  
pp. 633-641 ◽  
Author(s):  
Sarah F. Schillie ◽  
Lauren Canary ◽  
Alaya Koneru ◽  
Noele P. Nelson ◽  
Wade Tanico ◽  
...  

2016 ◽  
Vol 3 (1) ◽  
pp. 48
Author(s):  
Annisaa’ Nurmasari ◽  
Fatimah Fatimah ◽  
Febrina Suci Hati

<p>HIV infection in pregnant women can threaten the life of the mother and the mother can transmit the virus to their babies. Sleman PHC registered 2 people including one pregnant woman and one women of childbearing age in the year of 2014. Incidence of pregnant women suffering from HIV-AIDS in 2014 is 1 patients and detected from PITC test results for 7 weeks in a row is 1 patient. And in January year of 2015 found 1 patient with 3 times test and the results was positive. The purpose of this study was to determine relationship between Knowledge Level of Pregnant women about HIV/AIDS and Behaviour of PITC (Provider Initiated Test and Counselling) test. This study was a quantitative analysis of correlation with cross-sectional design. The population of this study were all pregnant women checkups at the health center in Yogyakarta Sleman. The sampling technique was used accidental sampling study which consisted of 72 respondents. The analysis used univariate and bivariate. The results showed that most respondents aged 20-35 (72.2%), senior high school education (47.2%) and work as a housewife (IRT) (38.9%). Most respondents have good knowledge about HIV/AIDS were 50 respondents (69.4%). Most respondents perform checks PITC were 71 respondents (98.6%). There was no relationship between knowledge level of pregnant women about HIV/AIDS and Behaviour of PITC (p-value=0.243&gt;0.005). In Conclusion, There was no relationship between knowledge level of pregnant women about HIV/AIDS and Behaviour of PITC in Sleman, Yogyakarta.</p>


2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
T Petkova ◽  
S Pachkova ◽  
T z Doichinova ◽  
S Aleksandrova-Yankulovska

Abstract Background Parvovirus B19 is a widespread infection in childhood. Seroprevalence of anti-Parvovirus B19 increases with age and about 60% to 70% of women of childbearing age have serological evidence of past exposure to virus. Diaplacental Parvovirus B19 infection in pregnant women can lead to anaemia, non-immune hydrops fetalis and foetal death. The aim of the study is determining the susceptibility to Parvovirus B19 in childbearing age women. Methods We conducted a prospective seroepidemiological study in which 90 healthy women of childbearing age (19 to 40 years) were tested during the period September-October 2018 in Medical Center “Clinical Institute for Reproductive Medicine”- Pleven, Bulgaria. Participants were surveyed on a voluntary basis. The exclusion criteria were: presence of autoimmune disorder, immunosuppressive states, malignancy and populations at risk such as persons under 18 years of age and pregnant women. The presence of specific Parvovirus B19 IgG was detected using a standardized anti-Parvovirus B19 (IgG) ELISA kit. The demographic and anamnestic data were collected for each participant in Case Report Form. Results The average age of the women was 31.4 ± 4.9 years. Dominating were women with higher education (52.2%) living in urban areas (92.2%). The survey results showed that 37.8% of women were positive for anti-Parvovirus B19 IgG, 61.1% were negative and 1.1% equivocal. Immunty to the virus increased from 27.3% to 45% with age. There was no significant correlation between the presence of antibodies and the demographic factors (living area, education and number of family members). Conclusions The results of this study imply that 61.1% of the childbearing age women in Pleven region are susceptible to infection with Parvovirus B19. Because of the high susceptibility to Parvovirus B19, active monitoring of risk groups pregnant women for the prevention of fetal complications is recommended. Key messages There is no specific treatment or prophylaxis against Parvovirus B19 infection and epidemiological surveillance requires the introduction of effective preventive measures at the public health level. Active monitoring in childbearing age women is necessary to reduce the risk of fetal damage and the cost of healthcare associated with the infection.


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