Replication of measles virus in human lymphocytes.
1985 ◽
Vol 161
(6)
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pp. 1261-1271
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Keyword(s):
Replication of measles virus was restricted in human peripheral blood mononuclear cells (PBMC). However, in in vitro-infected, unstimulated cells, active synthesis of viral RNA and proteins occurred, while the release of infectious virus could not be detected. Stimulation with PHA caused a productive infection cycle comparable to the lytic infection. Replication of viral RNA was demonstrated in both T and B cells, and in both OKT4+- and OKT8+-depleted T cell subsets. The presence of measles virus RNA was detected in PBMC isolated from measles patients, and the production of the immunoreactive hemagglutinin protein was defective in these cells.
1987 ◽
Vol 104
(2)
◽
pp. 183-187
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1999 ◽
Vol 73
(2)
◽
pp. 1695-1698
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1999 ◽
Vol 134
(1)
◽
pp. 49-55
◽
2012 ◽
Vol 209
(2)
◽
pp. 235-241
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