scholarly journals THE COMPARATIVE RESISTANCE OF BACTERIA AND HUMAN TISSUE CELLS TO CERTAIN COMMON ANTISEPTICS

1916 ◽  
Vol 24 (6) ◽  
pp. 683-688 ◽  
Author(s):  
Robert A. Lambert

The comparative resistance of bacteria and human tissue cells to antiseptics and other chemicals may be easily tested by tissue cultures under conditions which approximate those found in the living body. A comparative study shows that while human cells (connective tissue and wandering cells) are highly resistant to many antiseptics, they are in general more easily killed than bacteria (Staphylococcus aureus). Of the antiseptics tested, which include mercuric chloride, iodine, potassium mercuric iodide, phenol, tricresol, hydrogen peroxide, hypochlorites (Dakin's solution), argyrol, and alcohol, the one which approaches most closely the ideal disinfectant is iodine, which kills bacteria in strengths that do not seriously injure connective tissue cells or wandering cells.

1922 ◽  
Vol 35 (3) ◽  
pp. 317-322 ◽  
Author(s):  
Margaret Reed Lewis

It is not advisable to enter into a discussion of these findings at the present time, owing to the lack of experimental evidence as to the exact nature of the vacuoles. Regardless of the nature of these bodies or of what factors produce them, they are structures abnormal to the connective tissue cells. The lack of dextrose in the medium of tissue cultures leads to some condition distinctly detrimental to the cells, resulting in their vacuolation and death, even when the medium contains abundant protein material. The addition of small amounts (0.5 to 1 per cent) of dextrose to the medium delays the formation of vacuoles and prolongs the life of the culture. The addition of large amounts (2 to 5 per cent) prevents vacuolation of the cells, but so much dextrose usually leads to a change in the hydrogen ion concentration of the culture resulting in an acid condition which arises coincidentally with the degeneration of the cells.


2003 ◽  
Vol 762 ◽  
Author(s):  
H. Águas ◽  
L. Pereira ◽  
A. Goullet ◽  
R. Silva ◽  
E. Fortunato ◽  
...  

AbstractIn this work we present results of a study performed on MIS diodes with the following structure: substrate (glass) / Cr (2000Å) / a-Si:H n+ (400Å) / a-Si:H i (5500Å) / oxide (0-40Å) / Au (100Å) to determine the influence of the oxide passivation layer grown by different techniques on the electrical performance of MIS devices. The results achieved show that the diodes with oxides grown using hydrogen peroxide present higher rectification factor (2×106)and signal to noise (S/N) ratio (1×107 at -1V) than the diodes with oxides obtained by the evaporation of SiO2, or by the chemical deposition of SiO2 by plasma of HMDSO (hexamethyldisiloxane), but in the case of deposited oxides, the breakdown voltage is higher, 30V instead of 3-10 V for grown oxides. The ideal oxide thickness, determined by spectroscopic ellipsometry, is dependent on the method used to grow the oxide layer and is in the range between 6 and 20 Å. The reason for this variation is related to the degree of compactation of the oxide produced, which is not relevant for applications of the diodes in the range of ± 1V, but is relevant when high breakdown voltages are required.


Diabetes ◽  
1991 ◽  
Vol 40 (5) ◽  
pp. 605-611 ◽  
Author(s):  
P. Muona ◽  
J. Peltonen ◽  
S. Jaakkola ◽  
J. Uitto

1990 ◽  
Vol 55 (10) ◽  
pp. 2377-2380
Author(s):  
Hamza A. Hussain

Nitroxide free radicals prepared from diethylamine, piperidine and pyrrolidine by oxidation with hydrogen peroxide were studied by ESR spectroscopy. The changes in the 14N splitting constant (aN) caused by the addition of KBr or tetraethylammonium bromide were measured in dependence on the concentration of the ions. For diethylamine nitroxide and piperidine nitroxide, the results are discussed in terms of two equilibria: the one, involving the anion, is associated with a gain or loss of hydrogen bonds to the nitroxide oxygen atom, the other is associated with the formation of solvent shared units involving the cation, which results in changes in the hydrogen bonding strenght. The large increase in the aN value in the case of pyrrolidine nitroxide is explained in terms of an interaction from one side of the positively charged N atom; the increase in aN in the case of diethylamine and piperidine nitroxides is explained in terms of interactions with both sides of the positively charged N atom.


Author(s):  
Michael P. Lynch

This chapter argues that academic freedom is justified because it is an inherently epistemic practice that serves the ideals of democracy. With Dewey, it is argued that “The one thing that is inherent and essential [to the idea of a university] is the ideal of truth.” But far from being apolitical, the value of pursuing truth and knowledge—the value that justifies academic freedom, both within and without the public mind—is a fundamental democratic value, and for three reasons: the practices of academic inquiry exemplify rational inquiry of the kind needed for democratic deliberation; those practices serve to train students to pursue that kind of inquiry; and those practices are important engines of democratic dissent.


2021 ◽  
Vol 37 (01) ◽  
pp. 045-052
Author(s):  
Mario Bazanelli Junqueira Ferraz ◽  
Guilherme Constante Preis Sella

AbstractNasal dorsal preservation surgery was described more than 100 years ago, but recently has gained prominence. Our objective is to show the surgical technique, the main indications and counterindications, and the complications. It is a technique that does not cause the detachment of the upper lateral cartilage (ULC) from the nasal septum, and has the main following sequence: preparation of the septum and its resection can be at different levels (high or low, i.e., SPAR [septum pyramidal adjustment and repositioning] A or B); preparation of the pyramid; transversal osteotomy; lateral osteotomy(s); and septopyramidal adjustment. The result is a nose with a lower radix than the original, a deprojection of the nasal dorsum tending to maintain its original shape; an increase in the interalar distance (IAD) and enlargement of the nasal middle ⅓; and loss of projection of the nasal tip and roundness of the nostrils. Thus, the ideal candidate is the one who benefits from such side effects, that is: tension nose, that is, high radix with projected dorsum, projected anterior nasal septal angle (ANSA), narrow middle ⅓, narrow IAD, thin nostrils and straight perpendicular plate of the ethmoid (PPE), and, depending on the characteristics, the deviated nose. The counterindications are low radix, irregularities in the nasal dorsum, ANSA lower than rhinion, and a wide middle ⅓. And the main stigmas are: a nose with a very low radix, middle ⅓ enlarged, residual hump, and saddling of the supratip area. Other issues of this technique are: the shape of the radix; the need or not to remove PPE; wide dorsum; irregular dorsum; ANSA lower than rhinion; weak cartilages; long nasal bone; deviated PPE; and obsessive patient. We conclude that this is a great technique for noses with characteristics suitable to it; care must be taken with the stigmas it can cause.


2008 ◽  
Vol 10 (1) ◽  
pp. 22-27 ◽  
Author(s):  
Roch Plewik ◽  
Piotr Synowiec ◽  
Janusz Wójcik

Two-phase CFD simulation of the monodyspersed suspension hydraulic behaviour in the tank apparatus from a circulatory pipe The hydrodynamics in fluidized-bed crystallizers is studied by CFD method. The simulations were performed by a commercial packet of computational fluid dynamics Fluent 6.x. For the one-phase modelling (15), a standard k-ε model was applied. In the case of the two-phase flows the Eulerian multi-phase model with a standard k-ε method, aided by the k-ε dispersed model for viscosity, has been used respectively. The collected data put a new light on the suspension flow behaviour in the annular zone of the fluidised bed crystallizer. From the presented here CFD simulations, it clearly issues that the real hydraulic conditions in the fluidised bed crystallizers are far from the ideal ones.


2019 ◽  
Vol 5 (1) ◽  
pp. eaav0216 ◽  
Author(s):  
Mohammad Arifuzzaman ◽  
Yuvon R. Mobley ◽  
Hae Woong Choi ◽  
Pradeep Bist ◽  
Cristina A. Salinas ◽  
...  

Mast cells (MCs) are strategically distributed at barrier sites and prestore various immunocyte-recruiting cytokines, making them ideal targets for selective activation to treat peripheral infections. Here, we report that topical treatment with mastoparan, a peptide MC activator (MCA), enhances clearance ofStaphylococcus aureusfrom infected mouse skins and accelerates healing of dermonecrotic lesions. Mastoparan functions by activating connective tissue MCs (CTMCs) via the MRGPRX2 (Mas-related G protein-coupled receptor member X2) receptor. Peripheral CTMC activation, in turn, enhances recruitment of bacteria-clearing neutrophils and wound-healing CD301b+dendritic cells. Consistent with MCs playing a master coordinating role, MC activation also augmented migration of various antigen-presenting dendritic cells to draining lymph nodes, leading to stronger protection against a second infection challenge. MCAs therefore orchestrate both the innate and adaptive immune arms, which could potentially be applied to combat peripheral infections by a broad range of pathogens.


2005 ◽  
Vol 7 (2) ◽  
pp. 139-163 ◽  
Author(s):  
Richard L. Venezky

Philologists, linguists, and educators have insisted for several centuries that the ideal orthography has a one-to-one correspondence between grapheme and phoneme. Others, however, have suggested deviations for such functions as distinguishing homophones, displaying popular alternative spellings, and retaining morpheme identity. If, indeed, the one-to-one ideal were accepted, the International Phonetic Alphabet should become the orthographic standard for all enlightened nations, yet the failure of even a single country to adopt it for practical writing suggests that other factors besides phonology are considered important for a writing system. Whatever the ideal orthography might be, the practical writing systems adopted upon this earth reflect linguistic, psychological, and cultural considerations. Knowingly or unknowingly, countries have adopted orthographies that favour either the early stages of learning to read or the advanced stages, that is, the experienced reader. The more a system tends towards a one-to-one relationship between graphemes and phonemes, the more it assists the new reader and the non-speaker of the language while the more it marks etymology and morphology, the more it favours the experienced reader. The study of psychological processing in reading demonstrates that human capacities for processing print are so powerful that complex patterns and irregularities pose only a small challenge. Orthographic regularity is extracted from lexical input and used to recognise words during reading. To understand how such a system develops, researchers should draw on the general mechanisms of perceptual learning.


2011 ◽  
Vol 65 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Milena Miljkovic ◽  
Milovan Purenovic ◽  
Mile Novakovic ◽  
Sonja Randjelovic

In this study the influence of the different fluorescent brightener Periblanc BA concentrations on the degree of knitted cotton fabric whiteness was investigated. Two consecutive experimental runs were performed. The first was the bleaching of the knitted cotton fabric with hydrogen peroxide using the methods of two and single bath exhaustion while the second was the optical bleaching with fluorescent brightener Periblanc BA using the exhaustion method. CIE Whiteness Index and Tint value were measured on the Color-Eye 3000 spectrophotometer at the standard illuminant D65 (Ice-Texicon, d/8, D65/10?) while K/S values were determined using the Kubelka Munk equation. The results show that cotton fabric bleached with fluorescent brightener Periblanc BA after bleaching with hydrogen peroxide using two bath exhaustion method has higher degree of whiteness (118.8) with a reddish tint in comparison to the one bleached with hydrogen peroxide using single bath method (106.1).


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