Manufacturing and characterization of encapsulated microfibers with different molecular weight poly(ε-caprolactone) (PCL) resins using a melt electrospinning technique

2016 ◽  
Vol 3 (2) ◽  
pp. 025301 ◽  
Author(s):  
Jason K Lee ◽  
Junghyuk Ko ◽  
Martin B G Jun ◽  
Patrick C Lee
Keyword(s):  
Molecular Weight ◽  
Electrospinning Technique ◽  
Melt Electrospinning ◽  
Different Molecular Weight

scholarly journals Nano-Assemblies from Amphiphilic PnBA-b-POEGA Copolymers as Drug Nanocarriers

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1164
Author(s):  
Angeliki Chroni ◽  
Thomas Mavromoustakos ◽  
Stergios Pispas
Keyword(s):  
Molecular Weight ◽  
Chain Transfer ◽  
Raft Polymerization ◽  
Polymeric Nanocarriers ◽  
Reversible Addition ◽  
2D Noesy ◽  
Drug Nanocarriers ◽  
Glycol Methyl Ether ◽  
Different Molecular Weight

The focus of this study is the development of highly stable losartan potassium (LSR) polymeric nanocarriers. Two novel amphiphilic poly(n-butyl acrylate)-block-poly(oligo(ethylene glycol) methyl ether acrylate) (PnBA-b-POEGA) copolymers with different molecular weight (Mw) of PnBA are synthesized via reversible addition fragmentation chain transfer (RAFT) polymerization, followed by the encapsulation of LSR into both PnBA-b-POEGA micelles. Based on dynamic light scattering (DLS), the PnBA30-b-POEGA70 and PnBA27-b-POEGA73 (where the subscripts denote wt.% composition of the components) copolymers formed micelles of 10 nm and 24 nm in water. The LSR-loaded PnBA-b-POEGA nanocarriers presented increased size and greater mass nanostructures compared to empty micelles, implying the successful loading of LSR into the inner hydrophobic domains. A thorough NMR (nuclear magnetic resonance) characterization of the LSR-loaded PnBA-b-POEGA nanocarriers was conducted. Strong intermolecular interactions between the biphenyl ring and the butyl chain of LSR with the methylene signals of PnBA were evidenced by 2D-NOESY experiments. The highest hydrophobicity of the PnBA27-b-POEGA73 micelles contributed to an efficient encapsulation of LSR into the micelles exhibiting a greater value of %EE compared to PnBA30-b-POEGA70 + 50% LSR nanocarriers. Ultrasound release profiles of LSR signified that a great amount of the encapsulated LSR is strongly attached to both PnBA30-b-POEGA70 and PnBA27-b-POEGA73 micelles.

scholarly journals Physico-chemical characterization of chitosan-based edible films incorporating bioactive compounds of different molecular weight

2011 ◽  
Vol 106 (2) ◽  
pp. 111-118 ◽  
Author(s):  
Ana I. Bourbon ◽  
Ana C. Pinheiro ◽  
Miguel A. Cerqueira ◽  
Cristina M.R. Rocha ◽  
Maria C. Avides ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Bioactive Compounds ◽  
Chemical Characterization ◽  
Edible Films ◽  
Physico Chemical ◽  
Different Molecular Weight

scholarly journals Synthesis and characterization of some modified polyvinyl alcohol

2004 ◽  
Vol 1 (2) ◽  
pp. 295-299
Author(s):  
Baghdad Science Journal
Keyword(s):  
Molecular Weight ◽  
Polyvinyl Alcohol ◽  
Acid Chloride ◽  
Thionyl Chloride ◽  
Synthesis And Characterization ◽  
Different Molecular Weight

Some esters were prepared from reaction of different molecular weight of PVA with some acid chloride (prepared by reaction of acid with thionyl chloride or phosphorous pentachloride)in the presence of pyridine. The thermal and reological properties were studied. The increasing Of bulky groups decreasing stability of the thermal and reological properties.

scholarly journals Stability improvement and characterization of bioprinted pectin-based scaffold

2019 ◽  
Vol 17 (1) ◽  
pp. 228080001880710 ◽  
Author(s):  
Samuel Stealey ◽  
Xiaoru Guo ◽  
Lixia Ren ◽  
Elizabeth Bryant ◽  
Matey Kaltchev ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Molecular Weight ◽  
Scanning Electron Microscopy ◽  
Cross Linker ◽  
Post Modification ◽  
Enhanced Stability ◽  
Different Molecular Weight ◽  
Scanning Electron ◽  
Sem Analyses

Purpose: Bioprinting is an alternative method for constructing tissues/organs for transplantation. This study investigated the cross-linker influence and post-printing modification using oligochitosan and chitosan for stability improvement. Methods: Oligochitosan was tested as a novel cross-linker to replace Ca2+ for pectin-based bio-ink. Oligochitosan (2 kD) and different molecular weight of chitosan were used to modify the bioprinted scaffold. Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) were used to characterize the scaffolds. Results: Oligochitosan failed to serve as a viable cross-linker. Successful post-printing modification was confirmed by FTIR and SEM analyses. Conclusion: Regarding post-modification, chitosan-treated scaffolds showed enhanced stability compared to untreated scaffolds. In particular, scaffolds modified with 150 kD chitosan exhibited the highest stability.

Characterization of Porous TiO2 Films Prepared Using PEG of Different Molecular Weight

2011 ◽  
Vol 298 ◽  
pp. 253-256
Author(s):  
Li Li Yang ◽  
Jia Wei Bai ◽  
Wen Jie Zhang
Keyword(s):  
Molecular Weight ◽  
Surface Roughness ◽  
Wavelength Region ◽  
Total Pore Volume ◽  
Dip Coating ◽  
Tio2 Films ◽  
Average Pore ◽  
Glass Substrates ◽  
Different Molecular Weight

Porous TiO2 films were prepared through dip-coating on glass substrates using different molecular weight of PEG. Surface roughness increased with increasing PEG molecular weight. The film prepared with PEG400 was fairly smooth with slight roughness. The films prepared with high molecular PEG became rougher and there were some larger particles on the films. When the PEG molecular weight got higher, adsorption edge of the films tended to move toward shorter wavelength region. In the wavelength range between 350 and 450 nm, larger PEG molecules made higher film transmittance. The particles prepared using higher or lower molecular weight of PEG had less surface area than using PEG1000. The average pore sizes were 14 nm, 15 nm, 28 nm, and 52 nm, and the total pore volume were 0.12 ml/g, 0.13 ml/g, 0.08 ml/g, and 0.09 ml/g for the TiO2 powders prepared using PEG400 to PEG 6000.

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