TOPAS Monte Carlo model of MD anderson scanning proton beam for simulation studies in proton therapy

2018 ◽  
Vol 4 (3) ◽  
pp. 037001 ◽  
Author(s):  
J Hartman ◽  
X Zhang ◽  
X R Zhu ◽  
S J Frank ◽  
J J W Lagendijk ◽  
...  
2015 ◽  
Vol 42 (6Part12) ◽  
pp. 3341-3341
Author(s):  
C Xie ◽  
H Lin ◽  
J Jing ◽  
C Chen ◽  
R Cao ◽  
...  

2012 ◽  
Vol 39 (6Part17) ◽  
pp. 3818-3818 ◽  
Author(s):  
V Moskvin ◽  
C Cheng ◽  
V Anferov ◽  
D Nichiporov ◽  
Q Zhao ◽  
...  

Author(s):  
Zahra Sadat Tabatabaeian ◽  
Mahdi Sadeghi ◽  
Mohammad Reza Ghasemi

In the passive method of proton therapy, range modulation wheel is used to scatter the single energy proton beam. It rounds and scatters the single energy proton beam to the spectrum of particles that covers cancerous tissue by a change in penetration depth. Geant4 is a Monte Carlo simulation platform for studying particles behaviour in a matter. We simulated proton therapy nozzle with Geant4. Geometric properties of this nozzle have some effects on this beam absorption plot. Concerning the relation between penetration depth and proton particle energy, we have designed a range modulation wheel to have an approximately flat plot of absorption energy. An iterative algorithm programming helped us to calculate the weight and thickness of each sector of range modulation wheel. Flatness and practical range are calculated for resulting spread-out Bragg peak.


2007 ◽  
Vol 34 (6Part14) ◽  
pp. 2503-2503
Author(s):  
U Titt ◽  
N Sahoo ◽  
R Zhu ◽  
X Ding ◽  
Y Zheng ◽  
...  

Author(s):  
Bing-Hao Chiang ◽  
Austin Bunker ◽  
Hosang Jin ◽  
Salahuddin Ahmad ◽  
Yong Chen

Abstract Aim: As the number of proton therapy facilities has steadily increased, the need for the tool to provide precise dose simulation for complicated clinical and research scenarios also increase. In this study, the treatment head of Mevion HYPERSCAN pencil beam scanning (PBS) proton therapy system including energy modulation system (EMS) and Adaptive Aperture™ (AA) was modelled using TOPAS (TOolkit for PArticle Simulation) Monte Carlo (MC) code and was validated during commissioning process. Materials and methods: The proton beam characteristics including integral depth doses (IDDs) of pristine Bragg peak and in-air beam spot sizes were simulated and compared with measured beam data. The lateral profiles, with and without AA, were also verified against calculation from treatment planning system (TPS). Results: All beam characteristics for IDDs and in-air spot size agreed well within 1 mm and 10% separately. The full width at half maximum and penumbra of lateral dose profile also agree well within 2 mm. Finding: The TOPAS MC simulation of the MEVION HYPERSCAN PBS proton therapy system has been modelled and validated; it could be a viable tool for research and verification of the proton treatment in the future.


2017 ◽  
Vol 3 (2) ◽  
pp. 83-86
Author(s):  
Martin Dommert ◽  
Marcel Reginatto ◽  
Miroslav Zboril ◽  
Fine Fiedler ◽  
Stephan Helmbrecht ◽  
...  

AbstractMeasurement of the energy spectrum of secondary neutrons were carried out at the OncoRay Proton Therapy facility in Dresden, following an approach originating in neutron metrology which is well suited for both the characterization of secondary neutron fields at proton therapy facilities and the validation of Monte Carlo simulations. For the experiment, a brass target was placed in the proton beam and Bonner spheres measurements were made at a distance of 2 m from the target and at different angles, 15° to 120°, with respect to the incoming proton beam. The measured spectra were compared to Monte Carlo simulations.


Nukleonika ◽  
2014 ◽  
Vol 59 (2) ◽  
pp. 61-66 ◽  
Author(s):  
Małgorzata Grządziel ◽  
Adam Konefał ◽  
Wiktor Zipper ◽  
Robert Pietrzak ◽  
Ewelina Bzymek

Abstract Verification of calculations of the depth-dose distributions in water, using GEANT4 (version of 4.9.3) and MCNPX (version of 2.7.0) Monte Carlo codes, was performed for the scatterer-phantom system used in the dosimetry measurements in the proton therapy of eye tumours. The simulated primary proton beam had the energy spectra distributed according to the Gauss distribution with the cut at energy greater than that related to the maximum of the spectrum. The energy spectra of the primary protons were chosen to get the possibly best agreement between the measured relative depth-dose distributions along the central-axis of the proton beam in a water phantom and that derived from the Monte Carlo calculations separately for the both tested codes. The local depth-dose differences between results from the calculations and the measurements were mostly less than 5% (the mean value of 2.1% and 3.6% for the MCNPX and GEANT4 calculations). In the case of the MCNPX calculations, the best fit to the experimental data was obtained for the spectrum with maximum at 60.8 MeV (more probable energy), FWHM of the spectrum of 0.4 MeV and the energy cut at 60.85 MeV whereas in the GEANT4 calculations more probable energy was 60.5 MeV, FWHM of 0.5 MeV, the energy cut at 60.7 MeV. Thus, one can say that the results obtained by means of the both considered Monte Carlo codes are similar but they are not the same. Therefore the agreement between the calculations and the measurements has to be verified before each application of the MCNPX and GEANT4 codes for the determination of the depth-dose curves for the therapeutic protons.


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