Is Parental Report of Upper Respiratory Infection at the Onset of Obsessive–Compulsive Disorder Suggestive of Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection?

2002 ◽  
Vol 12 (2) ◽  
pp. 157-164 ◽  
Author(s):  
Lisa Giulino ◽  
Patricia Gammon ◽  
Kevin Sullivan ◽  
Martin Franklin ◽  
Edna Foa ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Respiratory Infection ◽  
Streptococcal Infection ◽  
Neuropsychiatric Disorder ◽  
Parental Report ◽  
Obsessive Compulsive ◽  
Upper Respiratory Infection ◽  
Compulsive Disorder ◽  
Upper Respiratory

Investigating Tourette Syndrome as a Neurologic Sequela of Rheumatic Fever

CNS Spectrums ◽  
1999 ◽  
Vol 4 (2) ◽  
pp. 62-67 ◽  
Author(s):  
Roger Kurlan
Keyword(s):  
Rheumatic Fever ◽  
Obsessive Compulsive Disorder ◽  
Tourette Syndrome ◽  
Research Evidence ◽  
Streptococcal Infection ◽  
Molecular Mimicry ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Neurologic Sequela ◽  
Immune Mediated

AbstractSydenham's chorea is currently recognized as the only neurologic sequela of rheumatic fever. Recent evidence suggests that there may be a spectrum of neurobehavioral disturbances, particularly including tics and obsessive-compulsive disorder, that develops following streptococcal infection by the process of molecular mimicry, whereby antibodies directed against bacterial antigens cross-react with brain targets. This proposed postinfectious, immune-mediated condition has been termed “pediatric autoimmune neuropsychiatric disorders after streptococcal infection” (PANDAS). This article reviews research evidence in favor and also against the PANDAS concept and discusses the implications of the hypothesis.

Diagnostic interview assessed neuropsychiatric disorder comorbidity in 334 individuals with obsessive-compulsive disorder

2004 ◽  
Vol 19 (3) ◽  
pp. 163-173 ◽  
Author(s):  
V. Holland LaSalle ◽  
Kiara R. Cromer ◽  
Kathryn N. Nelson ◽  
Diane Kazuba ◽  
Lucy Justement ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Diagnostic Interview ◽  
Neuropsychiatric Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

scholarly journals Azithromycin Prophylaxis in an Adolescent With PANDAS

2020 ◽  
Vol 25 (1) ◽  
pp. 61-63
Author(s):  
Paul Blankenship ◽  
Kenneth Kurek
Keyword(s):  
New York ◽  
Obsessive Compulsive Disorder ◽  
Symptom Onset ◽  
Streptococcal Infection ◽  
Neuropsychiatric Disorders ◽  
Adolescent Patient ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Treatment Management ◽  
Acute Symptom

Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) is a type of pediatric obsessive-compulsive disorder with an acute symptom onset and periodic recurrence that is triggered by streptococcal infection. Due in part to the multifaceted assessment involved in the diagnosis of PANDAS and lack of consensus on the best treatment, management of these cases is complex. A background and case of PANDAS exacerbation in an adolescent patient, who presented with visuomotor impairment and was treated with azithromycin (Zithromax, Pfizer, New York, NY) prophylaxis to prevent further clinical deterioration, is described here.

Obsessive compulsive disorder in adults with rheumatic heart disease

2007 ◽  
Vol 19 (2) ◽  
pp. 118-121 ◽  
Author(s):  
Ashfaq-U-Rahaman ◽  
Y. C Janardhan Reddy ◽  
Prabhavathi ◽  
Pramod Kumar Pal
Keyword(s):  
Heart Disease ◽  
General Population ◽  
Rheumatic Heart Disease ◽  
Obsessive Compulsive Disorder ◽  
Streptococcal Infection ◽  
Assessment Tools ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
History Of ◽  
Rheumatic Heart

Objective:There are considerable data on the possible association between streptococcal infection and obsessive compulsive disorder (OCD), particularly the relation between Sydenham’s chorea (SC) and OCD. However, neuropsychiatric sequelae related to streptococcal infection are mainly reported in children. In this preliminary study, we examined prevalence of OCD in a group of adult subjects with established rheumatic heart disease (RHD). We hypothesized that the rate of OCD would be higher than the known general population rates.Method:One hundred adult subjects with RHD were evaluated for OCD and other comorbid psychiatric disorders using well-known psychiatric assessment tools. A qualified psychiatrist conducted the assessments. The diagnoses were made according to DSM-IV criteria.Results:The rate of clinical OCD and subclinical OCD was 10% and 3%, respectively (n = 13), a rate much higher than the 1–3% rate reported in general population. Of the 13 subjects, only three had a history of SC (23%).Conclusions:OCD could be a long-term sequel in adults with a history of rheumatic fever in childhood, even in the absence of frank chorea. The findings call for systematic research in this little explored area.

scholarly journals Disease Severity and Social Adjustment of Patients with Obsessive Compulsive Disorder from West Bengal

2016 ◽  
Vol 3 (4) ◽  
Author(s):  
Rima Das ◽  
Souvik Raychaudhuri
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Disease Severity ◽  
Social Adjustment ◽  
Rural Population ◽  
Urban Areas ◽  
West Bengal ◽  
The State ◽  
Neuropsychiatric Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Obsessive-Compulsive disorder (OCD) is a neuropsychiatric disorder prevalent in population worldwide. In the present study we investigated OCD patients from the state of West Bengal, India. Patients were evaluated for social adjustment using Rosenzweig PF test and severity of OCD using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS). It was found that patients from urban areas had poor social adjustment compared to those from semirural areas. Rural population fared well in adjustment in spite of disease.

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