Evaluation of Reproductive Toxicology of Aqueous Extract of Yerba Mate (Ilex paraguariensis A. St.-Hil.), a Traditional South American Beverage

2019 ◽  
Vol 22 (1) ◽  
pp. 97-101
Author(s):  
Washington Rogério de Sousa ◽  
Bruno Henrique Lopes Botelho Lourenço ◽  
Michelle de Paula Reis ◽  
Guilherme Donadel ◽  
Marcia Alessandra Arantes Marques ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Ilex Paraguariensis ◽  
South American ◽  
Yerba Mate ◽  
Reproductive Toxicology

The effect of aqueous extract of gross and commercial yerba mate (Ilex paraguariensis) on intra-abdominal and epididymal fat and glucose levels in male Wistar rats

Fitoterapia ◽  
2011 ◽  
Vol 82 (6) ◽  
pp. 818-826 ◽  
Author(s):  
Raquel D'Agostini Silva ◽  
Audrin Loss Scopel Bueno ◽  
Carin Weirich Gallon ◽  
Luana Ferreira Gomes ◽  
Samuel Kaiser ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Wistar Rats ◽  
Ilex Paraguariensis ◽  
Yerba Mate ◽  
Glucose Levels ◽  
Epididymal Fat ◽  
Male Wistar Rats

scholarly journals Arsenic, cadmium and lead concentrations in Yerba mate commercialized in Southern Brazil by inductively coupled plasma mass spectrometry

2017 ◽  
Vol 47 (12) ◽  
Author(s):  
Lisia Maria Gobbo dos Santos ◽  
Santos Alves Vicentini Neto ◽  
Giovanna Iozzi ◽  
Silvana do Couto Jacob
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Ilex Paraguariensis ◽  
South American ◽  
Yerba Mate ◽  
Southern Brazil ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry ◽  
Cadmium Lead ◽  
Cadmium And Lead

ABSTRACT: “Mate” or “Yerba Mate” (Ilex paraguariensis) is a native South American plant, commonly consumed in Argentina, Paraguay, Uruguay and southern Brazil. Recent research has detected the presence of many vitamins and metals in this plant. Theses metals are also part of yerba mate’s mineral composition, due to soil and water contamination by pesticides and fertilizers, coal and oil combustion, vehicle emissions, mining, smelting, refining and the incineration of urban and industrial waste. Regardless of their origin, some inorganic elements, such as arsenic, cadmium and lead, are considered toxic, since they accumulate in all plant tissues and are, thus, introduced into the food chain. In this context, the aim of the present study was to determine and compare arsenic, cadmium, lead concentrations in 104 samples of yerba mate (Ilex paraguariensis) marketed, and consumed in three southern Brazilian States, namely Paraná (PR), Santa Catarina (SC) and Rio Grande do Sul (RS). Each element was determined by inductively coupled plasma mass spectrometry (ICP-MS), on a Nexion 300D equipment (Perkin Elmer). As, Cd and Pb concentrations in yerba mate leaves ranged from 0.015 to 0.15mg kg-1, 0.18 to 1.25mg kg-1 and 0.1 to 1.20mg kg-1, respectively. Regarding Cd, 84% of the samples from RS, 63% from PR and 75% from SC showed higher concentrations than the maximum permissible limit of 0.4mg kg-1 established by the Brazilian National Sanitary Surveillance Agency (ANVISA), while 7% of the samples from RS and 5% from PR were unsatisfactory for Pb. Concentrations were below the established ANVISA limit of 0.6mg kg-1 for all samples.

scholarly journals Bread with Yerba Mate Aqueous Extract (Ilex paraguariensis A.St.-Hil.)

2015 ◽  
Vol 10 (5) ◽  
pp. 206-214 ◽  
Author(s):  
Christiane Faccin ◽  
Sarah Alberti ◽  
Lisiane Frare ◽  
Leticia R. Vieira ◽  
Myriam de las M. Salas-Mell ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Ilex Paraguariensis ◽  
Yerba Mate

scholarly journals Anti-proliferative activity of yerba mate (Ilex paraguariensis) aqueous extracts on human colorectal cancer cell lines

2021 ◽  
Vol 11 (10) ◽  
pp. 499
Author(s):  
Ali Jason Saleh ◽  
Leen Othman ◽  
Michel Elchoueiry ◽  
Rita Ghanem ◽  
Samer Bazzi ◽  
...  
Keyword(s):  
Cell Lines ◽  
Aqueous Extract ◽  
Proliferative Activity ◽  
Ilex Paraguariensis ◽  
Yerba Mate ◽  
Human Colorectal Cancer ◽  
Adenocarcinoma Cell ◽  
Human Colorectal Cancer Cell ◽  
Colorectal Cancer Cell Lines ◽  
Ht 29

Background: Yerba mate, a popular, tea-like beverage prepared from the dried leaves of Ilex paraguariensis, is widely consumed, and has several reported health benefits. Compared with other herbal teas, the effect of yerba mate on human cells in the context of cancer has not been extensively studied. The method of extraction of bioactive compounds from the yerba mate leaves plays an important role in its effect on cancer cells. Methods: In this study we assessed the viability, anti-proliferative, and apoptotic effect of the aqueous yerba mate extract, prepared using the same conditions employed for consumption, on different human colorectal cancer cell lines (Caco-2, HT-29, and HCT116) and on the non-tumorigenic human colon epithelial cell line (NCM460).Results: Cytotoxicity of aqueous yerba mate extract was studied and a dose-dependent decrease in viability was observed in all the tested cell lines. At 24 hrs., viability decreased to 19.7% with Caco-2 cells, 2.7% with HCT116, and 8.4% with HT-29 cells at a concentration of 4.8 mg/mL of yerba mate extract. The effect was less prominent on the NCM460 cell line where the viability of cells at the same concentration was 65.2%. Yerba mate extract also showed concentration-dependent anti-proliferative effects as determined by the WST-1 proliferation kit. IC50 values ranged between 0.22-0.69 mg/mL at 24 hr for cell lines tested. To study whether cell death was due to apoptosis, Caco-2 cells were stained with Annexin V-FITC assay and an increase in the percentage of late apoptotic Caco-2 cells was observed with yerba mate extract at 0.6-4.8 mg/mL. Cell cycle analysis using DNA content by flow cytometry showed an increase in the percentage of Caco-2 cells in the subG0/G1 phase and the G0/G1 phase after treatment with 2.4 mg/mL extract. Collectively, our data suggest that yerba mate aqueous extract exhibits an anti-proliferative effect on tested cell lines by inducing apoptosis.  Conclusions: Yerba mate aqueous extract exhibits a strong anti-proliferative activity against adenocarcinoma cell lines studied and constitutes a promising functional food adjuvant to anti-cancer therapy. Further work is needed to identify active components and mechanisms of action. Keywords: Aqueous extract, yerba mate, anti-proliferative activity, adenocarcinoma cell lines 

scholarly journals rial activity of Ilex paraguariensis (Yerba Mate) against Gram-positive and Gram-negative bacteria

2018 ◽  
Vol 12 (09) ◽  
pp. 712-719 ◽  
Author(s):  
Tania Noureddine ◽  
Ziad El Husseini ◽  
Ali Nehme ◽  
Roula Abdel Massih
Keyword(s):  
Antibacterial Activity ◽  
Aqueous Extract ◽  
Clinical Isolates ◽  
Ilex Paraguariensis ◽  
Minimal Bactericidal Concentration ◽  
Yerba Mate ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative ◽  
Stems And Leaves

Introduction: The stems and leaves of Ilex paraguariensis are popularly used for tea infusions in South America and the Middle East. The health benefits have been previously studied, revealing anti-mutagenic, anti-oxidant, hepatoprotective, hypocholesteremic and glycemic improvement. Limited research was performed on the antibacterial activity of the aqueous extract of Yerba Mate on standard and clinical isolates of Gram-positive and Gram-negative bacteria. Methodology: Commercial Ilex paraguariensis stems and leaves were ground and extracted with sterile deionized water at 70°C. Four ATCC bacterial strains and twenty-five bacterial clinical strains were used for testing. To obtain the minimal inhibitory concentration (MIC), the Yerba Mate aqueous solution was serially diluted according to the microdilution method. For the minimal bactericidal concentration (MBC), the tubes with clear broth were sub-cultured. To identify the types of ESBLs present in the clinical isolates, a multiplex PCR was performed. Results: An antibacterial activity was observed against most of tested strains, with a greater activity against Gram-positive bacteria. MIC and MBC values ranged between 0.468 mg/mL and 15 mg/mL of aqueous extract of Yerba Mate. Conclusion: The aqueous extract of the stems and leaves of Ilex paraguariensis extracted at 70°C showed a significant antibacterial activity. There was no correlation found between the different molecular resistance profiles and the antibacterial activity range.

Aqueous Extracts of Yerba Mate (Ilex paraguariensis) as a Natural Antimicrobial against Escherichia coli O157:H7 in a Microbiological Medium and pH 6.0 Apple Juice

2012 ◽  
Vol 75 (4) ◽  
pp. 753-757 ◽  
Author(s):  
KELLIE P. BURRIS ◽  
P. M. DAVIDSON ◽  
C. NEAL STEWART ◽  
S. ZIVANOVIC ◽  
F. M. HARTE
Keyword(s):  
Escherichia Coli ◽  
Apple Juice ◽  
Ilex Paraguariensis ◽  
South American ◽  
Yerba Mate ◽  
Escherichia Coli O157 ◽  
Aqueous Extracts ◽  
Natural Antimicrobial ◽  
E Coli ◽  
Log Reduction

Ilex paraguariensis is popularly used in the preparation of a tea infusion (yerba mate), most commonly produced and consumed in the South American countries of Uruguay, Paraguay, Argentina, and Brazil. In this study, aqueous extracts of commercial tea, derived from the holly plant species I. paraguariensis were evaluated for their ability to inhibit or inactivate Escherichia coli O157:H7 in a microbiological medium and modified apple juice. Dialyzed, lyophilized aqueous extracts were screened for antimicrobial activity against E. coli O157:H7 strains ATCC 43894 and ‘Cider’ in tryptic soy broth (TSB) and apple juice (adjusted to pH 6.0 to allow for growth of the bacterium). A mixture of the two strains was used as the inoculum when apple juice was used as the medium. MBCs were determined to be ca. 5 and 10 mg/ml for ATCC 43894 and ‘Cider’, respectively, in TSB. Higher concentrations of the extract were required to inactivate E. coli O157:H7 in pH-adjusted apple juice. An approximate 4.5-log reduction was observed for E. coli O157:H7 treated with 40 mg/ml extract. It was concluded that aqueous extracts from commercial yerba mate have potential to be used as antimicrobials in foods and beverages against pathogenic E. coli O157:H7.

scholarly journals Antibacterial activity of Ilex paraguariensis (Yerba Mate) against Gram-positive and Gram-negative bacteria

2018 ◽  
Vol 12 (02.1) ◽  
pp. 13S
Author(s):  
Tania Noureddine ◽  
Ziad Al Husseini ◽  
Ali Nehme ◽  
Roula Abdel Massih
Keyword(s):  
Antibacterial Activity ◽  
Aqueous Extract ◽  
Phenylboronic Acid ◽  
Ilex Paraguariensis ◽  
Resistant Bacteria ◽  
Molecular Testing ◽  
Yerba Mate ◽  
Bacterial Strains ◽  
Gram Positive ◽  
Gram Negative

Introduction: Limited research was performed on the antibacterial activity of the aqueous extract of Yerba Mate. The purpose of this study is to evaluate the anti-bacterial activity of Yerba Mate against Gram-positive and Gram-negative bacterial strains and its action against some resistant bacteria with genotypic molecular testing of resistance profiles. Methodology: Commercial Ilex paraguariensis stems and leaves were purchased and extracts were prepared by adding water at 70oC for 2 hrs. ATCC bacterial strains and clinical strains from Centre Hospitalier Du Nord (CHN) were used for testing. Macro dilution method was used to determine the minimal inhibitory. Minimal bactericidal concentration (MBC) was determined by sub-culturing the tubes with clear broth. For phenotypic and genotypic detection of β-lactamases, Double Disk Synergy method, E-test, phenylboronic acid disc method and multiplex PCR were performed for the identification of the mechanisms of resistance. Results: Antibacterial activity was observed against all tested strains, with a greater activity against Gram-positive bacteria. This study showed mostly a greater antibacterial activity of aqueous extract of Yerba Mate in comparison to different extraction methods published. In general, the MIC and MBC values ranged between 0.468 mg/mL and 15 mg/mL. No correlation was found between the different molecular resistance profiles and the antibacterial activity. Conclusion: More studies are needed to determine the molecule or molecules responsible for this activity. Moreover, testing a wider range of bacterial isolates is important for a better understanding of the potential role of Yerba Mate.

scholarly journals Yerba mate aqueous extract improves the oxidative and inflammatory states of rats with adjuvant-induced arthritis

2019 ◽  
Vol 10 (9) ◽  
pp. 5682-5696 ◽  
Author(s):  
Vanesa Gesser Correa ◽  
Anacharis B. de Sá-Nakanishi ◽  
Geferson de Almeida Gonçalves ◽  
Lillian Barros ◽  
Isabel C. F. R. Ferreira ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Ilex Paraguariensis ◽  
Yerba Mate ◽  
Adjuvant Induced Arthritis

Healthy and adjuvant-induced arthritic rats were treated for 23 days with daily doses of 400 and 800 mg kg−1Ilex paraguariensis extract.

scholarly journals Bioactive compounds content of chimarrão infusions related to the moisture of yerba maté (Ilex Paraguariensis) leaves

2006 ◽  
Vol 49 (3) ◽  
pp. 399-404 ◽  
Author(s):  
Deborah H. M. Bastos ◽  
Ana Claudia Fornari ◽  
Yara S. Queiroz ◽  
Elizabeth A. F. S. Torres
Keyword(s):  
Moisture Content ◽  
Caffeic Acid ◽  
Aqueous Extract ◽  
Acid Content ◽  
Ilex Paraguariensis ◽  
Array Detector ◽  
Diode Array ◽  
Yerba Mate ◽  
Diode Array Detector ◽  
Bioactive Substances

The aim of this study was to evaluate the effects of the processing stages of yerba maté (Ilex paraguariensis) on the moisture content of the leaves and the efficiency of the aqueous extraction of some bioactive substances. Samples of yerba maté were analyzed for caffeine, phenolic acids (caffeic acid, 5-caffeoilquinic acid) and flavonoids (quercetin, kaempferol and myricetin) by HPLC equipped with a diode array detector. Processing widely influenced the caffeine and 5-caffeoilquinic acid content of the aqueous extract (p < 0.05), which was related to the moisture content of the leaves. Caffeic acid was present in 45% of the in infusions from dried mate leaves. Quercetin, myricetin and kaempferol were not detected.

Sign in / Sign up

Export Citation Format

Share Document