scholarly journals Association of Physical Activity Level and Stroke Outcomes in Men and Women: A Meta-Analysis

2010 ◽  
Vol 19 (10) ◽  
pp. 1815-1822 ◽  
Author(s):  
Lien Diep ◽  
John Kwagyan ◽  
Joseph Kurantsin-Mills ◽  
Roger Weir ◽  
Annapurni Jayam-Trouth
Gerontology ◽  
2021 ◽  
pp. 1-14
Author(s):  
Ahmed Ghachem ◽  
Frédérik Dufour ◽  
Tamas Fülöp ◽  
Pierrette Gaudreau ◽  
Alan A. Cohen

<b><i>Background:</i></b> Age-related changes in biological processes such as physiological dysregulation (the progressive loss of homeostatic capacity) vary considerably among older adults and may influence health profiles in late life. These differences could be related, at least in part, to the impact of intrinsic and extrinsic factors such as sex and physical activity level (PAL). <b><i>Objectives:</i></b> The objectives of this study were (1) to assess the magnitude and rate of changes in physiologi­cal dysregulation in men and women according to PAL and (2) to determine whether/how sex and PAL mediate the apparent influence of physiological dysregulation on health outcomes (frailty and mortality). <b><i>Methods:</i></b> We used data on 1,754 community-dwelling older adults (age = 74.4 ± 4.2 years; women = 52.4%) of the Quebec NuAge cohort study. Physiological dysregulation was calculated based on Mahalanobis distance of 31 biomarkers regrouped into 5 systems: oxygen transport, liver/kidney function, leukopoiesis, micronutrients, and lipids. <b><i>Results:</i></b> As expected, mean physiological dysregulation significantly increased with age while PAL decreased. For the same age and PAL, men showed higher levels of physiological dysregulation globally in 3 systems: oxygen transport, liver/kidney function, and leukopoiesis. Men also showed faster global physiological dysregulation in the liver/kidney and leukopoiesis systems. Overall, high PAL was associated with lower level and slower rate of change of physiological dysregulation. Finally, while mortality and frailty risk significantly increased with physiological dysregulation, there was no evidence for differences in these effects between sexes and PAL. <b><i>Conclusion:</i></b> Our results showed that both sex and PAL have a significant effect on physiological dysregulation levels and rates of change. Also, although a higher PAL was associated with lower level and slower rate of change of physiological dysregulation, there was no evidence that PAL attenuates the effect of physiological dysregulation on subsequent declines in health at the end of life. Substantial work remains to understand how modifiable behaviors impact the relationship between physiological dysregulation, frailty, and mortality in men and women.


2021 ◽  
Author(s):  
Mahnaz Azmodeh ◽  
Rastegar Hoseini ◽  
Ehsan Amiri

Abstract Background: New coronavirus (COVID-19) has a major impact on the individual's physical activity level (PAL); The COVID-19 quarantine outbreak caused a decrease in the PAL. Accordingly, it might also affect the general health and quality of life (QoL). This study aimed to evaluate the relationship between PAL with QoL and general health (GH) among COVID-19 recovered individuals (CRI).Methods: In this descriptive-analytical study, using the multi-stage (Cluster) sampling techniques, 890 CRI (male (n = 438) and female (n = 452)) were volunteered from different COVID-19 testing centers in Kermanshah province. After filling out the consent form, the PAL, GH, and QoL questionnaires were completed and anthropometric parameters were measured. The PAL was assessed using the international physical activity questionnaire (IPAQ-SF), GH was assessed using the GHQ questionnaire and the QoL was measured by the QoL questionnaire (short-form-SF-12). The independent t-test was used to compare the mean of variables between men and women and the Pearson correlation coefficient test was used to evaluate the relationship between variables using SPSS software version 24 at a significant level of (P≤0.05). Results: The findings of the present study showed that men and women with COVID-19 had inadequate PAL (876.11±40.23;739.08±27.02), insufficient GH (50.13±3.1; 54.15±4.28), and poor QoL (22.02±2.28; 19.23±1.87), respectively. The results also showed that men had significantly higher PAL (P=0.035), GH (P=0.047), and QoL (P=0.023) compared to women. Also, the results show that increasing the PAL improves GH and QoL. Conclusions: Considering the prevalence of COVID-19 and its negative impact on GH and QoL, maintaining adequate PAL can be considered as one of the effective strategies for improving physical and GH, and immune systems, by observing the hygiene protocol.


2016 ◽  
Vol 24 (4) ◽  
pp. 533-539 ◽  
Author(s):  
Nurdiana Zainol Abidin ◽  
Wendy J. Brown ◽  
Bronwyn Clark ◽  
Ahmad Munir Che Muhamed ◽  
Rabindarjeet Singh

We evaluated feasibility of physical activity measurement by accelerometry among older Malay adults living in semi-rural areas in Malaysia. Results showed that 95% of 146 participants (aged [SD] 67.6 [6.4] years) were compliant in wearing the accelerometer for at least five days. Fifteen participants were asked for re-wear the accelerometer because they did not have enough valid days during the first assessment. Participants wore the accelerometer an average of 15.3 hr in a 24-hr day, with 6.5 (1.2) valid wear days. No significant difference in valid wear day and time was found between men and women. Participants who are single provide more valid wear days compared with married participants (p < .05), and participants with higher levels of education provide longer periods of accelerometer wearing hours (p < .01). Eighty-seven percent of participants reported ‘no issues’ with wearing the meter. This study suggests that accelerometry is a feasible method to assess the physical activity level among older Malay adults living in semi-rural areas.


2005 ◽  
Vol 98 (1) ◽  
pp. 160-167 ◽  
Author(s):  
Michelle C. Venables ◽  
Juul Achten ◽  
Asker E. Jeukendrup

The aim of the present study was to establish fat oxidation rates over a range of exercise intensities in a large group of healthy men and women. It was hypothesised that exercise intensity is of primary importance to the regulation of fat oxidation and that gender, body composition, physical activity level, and training status are secondary and can explain part of the observed interindividual variation. For this purpose, 300 healthy men and women (157 men and 143 women) performed an incremental exercise test to exhaustion on a treadmill [adapted from a previous protocol (Achten J, Venables MC, and Jeukendrup AE. Metabolism 52: 747–752, 2003)]. Substrate oxidation was determined using indirect calorimetry. For each individual, maximal fat oxidation (MFO) and the intensity at which MFO occurred (Fatmax) were determined. On average, MFO was 7.8 ± 0.13 mg·kg fat-free mass (FFM)−1·min−1 and occurred at 48.3 ± 0.9% maximal oxygen uptake (V̇o2 max), equivalent to 61.5 ± 0.6% maximal heart rate. MFO (7.4 ± 0.2 vs. 8.3 ± 0.2 mg·kg·FFM−1·min−1; P < 0.01) and Fatmax (45 ± 1 vs. 52 ± 1% V̇o2 max; P < 0.01) were significantly lower in men compared with women. When corrected for FFM, MFO was predicted by physical activity (self-reported physical activity level), V̇o2 max, and gender ( R2 = 0.12) but not with fat mass. Men compared with women had lower rates of fat oxidation and an earlier shift to using carbohydrate as the dominant fuel. Physical activity, V̇o2 max, and gender explained only 12% of the interindividual variation in MFO during exercise, whereas body fatness was not a predictor. The interindividual variation in fat oxidation remains largely unexplained.


2020 ◽  
Vol 38 (3) ◽  
pp. 250-263
Author(s):  
Olayinka Akinrolie ◽  
Ruth Barclay ◽  
Shaelyn Strachan ◽  
Akanksha Gupta ◽  
Unyime S. Jasper ◽  
...  

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