PLK1 is required for chromosome compaction and microtubule organization in mouse oocytes
Keyword(s):
By deleting Plk1 in mouse oocytes before meiotic resumption, we show that PLK1 is essential for the formation of condensed bivalent chromosomes, microtubule organizing center fragmentation, liquid-like spindle domain localization, and bipolar spindle formation. Thus, PLK1 coordinates processes that ensure chromosome segregation during meiosis I.
2005 ◽
Vol 171
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pp. 27-33
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2013 ◽
Vol 202
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pp. 221-229
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2014 ◽
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pp. 3900-3908
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2004 ◽
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pp. 1609-1622
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2016 ◽
Vol 212
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pp. 829-843
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2015 ◽
Vol 209
(3)
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pp. 339-348
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