Mps1 promotes poleward chromosome movements in meiotic prometaphase
Keyword(s):
Mps1 is a kinase that regulates several steps in mitosis and meiosis. Mps1 is essential for the spindle checkpoint and helps stabilize attachment of kinetochores to microtubules. Here we show that following microtubule attachment, Mps1 promotes microtubule depolymerization to trigger migration of the chromosome toward the spindle pole.
1981 ◽
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