Effects of trans-10, cis-12 conjugated linoleic acid on body fat and serum lipids in young and adult hamsters

2006 ◽  
Vol 62 (2) ◽  
pp. 81-87 ◽  
Author(s):  
V. Navarro ◽  
J. Miranda ◽  
I. Churruca ◽  
A. Fernández-Quintela ◽  
V. M. Rodríguez ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Serum Lipids

Effect of supplementation with conjugated linoleic acid on human serum lipids and body fat

2001 ◽  
Vol 12 (10) ◽  
pp. 585-594 ◽  
Author(s):  
Vassilis Mougios ◽  
Antonis Matsakas ◽  
Anatoli Petridou ◽  
Susanne Ring ◽  
Angelos Sagredos ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Human Serum ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Serum Lipids

Effects of conjugated linoleic acid on body fat accumulation and serum lipids in hamsters fed an atherogenic diet

2003 ◽  
Vol 59 (3) ◽  
pp. 193-199 ◽  
Author(s):  
V. Navarro ◽  
A. Zabala ◽  
M. T. Macarulla ◽  
A. Fernández-Quintela ◽  
V. M. Rodríguez ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Serum Lipids ◽  
Atherogenic Diet ◽  
Fat Accumulation

scholarly journals A Supplement Containing Trans-10, Cis-12 Conjugated Linoleic Acid Reduces Milk Fat Yield but Does Not Alter Organ Weight or Body Fat Deposition in Lactating Ewes

2010 ◽  
Vol 140 (11) ◽  
pp. 1949-1955 ◽  
Author(s):  
Liam A. Sinclair ◽  
Weerasinghe M. P. B. Weerasinghe ◽  
Robert G. Wilkinson ◽  
Michael J. de Veth ◽  
Dale E. Bauman
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Milk Fat ◽  
Fat Deposition ◽  
Organ Weight ◽  
Fat Yield

Combined Effects of Dietary Protein Type and Fat Level on the Body Fat-Reducing Activity of Conjugated Linoleic Acid (CLA) in Rats

2005 ◽  
Vol 69 (12) ◽  
pp. 2409-2415 ◽  
Author(s):  
Asuka AKAHOSHI ◽  
Kazunori KOBA ◽  
Rie ENMOTO ◽  
Kazuko NISHIMURA ◽  
Yukiko HONDA ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Dietary Protein ◽  
The Body ◽  
Combined Effects ◽  
Fat Level ◽  
Reducing Activity

Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake

1999 ◽  
Vol 276 (4) ◽  
pp. R1172-R1179 ◽  
Author(s):  
James P. DeLany ◽  
Fawn Blohm ◽  
Alycia A. Truett ◽  
Joseph A. Scimeca ◽  
David B. West
Keyword(s):  
Body Composition ◽  
Linoleic Acid ◽  
Food Intake ◽  
Conjugated Linoleic Acid ◽  
Energy Intake ◽  
Body Fat ◽  
Metabolic Effects ◽  
Protein Accumulation ◽  
High Fat ◽  
Fat Accumulation

Recent reports have demonstrated that conjugated linoleic acid (CLA) has effects on body fat accumulation. In our previous work, CLA reduced body fat accumulation in mice fed either a high-fat or low-fat diet. Although CLA feeding reduced energy intake, the results suggested that some of the metabolic effects were not a consequence of the reduced food intake. We therefore undertook a study to determine a dose of CLA that would have effects on body composition without affecting energy intake. Five doses of CLA (0.0, 0.25, 0.50, 0.75, and 1.0% by weight) were studied in AKR/J male mice ( n = 12/group; age, 39 days) maintained on a high-fat diet (%fat 45 kcal). Energy intake was not suppressed by any CLA dose. Body fat was significantly lower in the 0.50, 0.75, and 1.0% CLA groups compared with controls. The retroperitoneal depot was most sensitive to the effects of CLA, whereas the epididymal depot was relatively resistant. Higher doses of CLA also significantly increased carcass protein content. A time-course study of the effects of 1% CLA on body composition showed reductions in fat pad weights within 2 wk and continued throughout 12 wk of CLA feeding. In conclusion, CLA feeding produces a rapid, marked decrease in fat accumulation, and an increase in protein accumulation, at relatively low doses without any major effects on food intake.

Conjugated linoleic acid does not reduce body fat but decreases hepatic steatosis in adult Wistar rats

2007 ◽  
Vol 18 (10) ◽  
pp. 676-684 ◽  
Author(s):  
Aparna Purushotham ◽  
Gayle E. Shrode ◽  
Angela A. Wendel ◽  
Li-Fen Liu ◽  
Martha A. Belury
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Hepatic Steatosis ◽  
Body Fat ◽  
Wistar Rats

scholarly journals Human health effects of conjugated linoleic acid from milk and supplements

2011 ◽  
Vol 24 (2) ◽  
pp. 206-227 ◽  
Author(s):  
Tracy A. McCrorie ◽  
Edel M. Keaveney ◽  
Julie M. W. Wallace ◽  
Nino Binns ◽  
M. Barbara E. Livingstone
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Human Health ◽  
Body Fat ◽  
Intervention Studies ◽  
Human Subjects ◽  
Scientific Evidence ◽  
Health Benefits ◽  
Health Claims

The primary purpose of the present review was to determine if the scientific evidence available for potential human health benefits of conjugated linoleic acid (CLA) is sufficient to support health claims on foods based on milk naturally enriched with cis-9, trans-11-CLA (c9, t11-CLA). A search of the scientific literature was conducted and showed that almost all the promising research results that have emerged in relation to cancer, heart health, obesity, diabetes and bone health have been in animal models or in vitro. Most human intervention studies have utilised synthetic CLA supplements, usually a 50:50 blend of c9, t11-CLA and trans-10, cis-12-CLA (t10, c12-CLA). Of these studies, the only evidence that is broadly consistent is an effect on body fat and weight reduction. A previous review of the relevant studies found that 3.2 g CLA/d resulted in a modest body fat loss in human subjects of about 0.09 kg/week, but this effect was attributed to the t10, c12-CLA isomer. There is no evidence of a consistent benefit of c9, t11-CLA on any health conditions; and in fact both synthetic isomers, particularly t10, c12-CLA, have been suspected of having pro-diabetic effects in individuals who are already at risk of developing diabetes. Four published intervention studies using naturally enriched CLA products were identified; however, the results were inconclusive. This may be partly due to the differences in the concentration of CLA administered in animal and human studies. In conclusion, further substantiation of the scientific evidence relating to CLA and human health benefits are required before health claims can be confirmed.

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