Follow-Up Data Improve the Estimation of the Prevalence of Heavy Alcohol Consumption

Background— Evidence on the relationship of a wide range of alcohol consumption with risk of incident atrial fibrillation has been limited. Methods— Between 1991 and 1995, 8602 Japanese men and women aged 30 to 80 years and free of clinical atrial fibrillation took part in the first examination of the Circulatory Risk in Communities Study(CIRCS)- a population based cohort study of cardiovascular risk factors, cardiovascular disease incidence, and their trends in Japanese communities. In the first examination, we checked a detailed medical history, physical examination, blood and urine examination, and electrocardiogram (ECG). An interviewer obtained histories in detail for weekly alcohol intake. In the follow-up period, incident atrial fibrillations were ascertained by annual ECG record and medical history of treatment of atrial fibrillation. ECGs were coded with the Minnesota Code by trained physician-epidemiologists. Differences in baseline characteristics between atrial fibrillation cases and controls were compared using Student t-tests or chi-squared tests. The hazard ratios (HRs) of incidence of atrial fibrillation and 95% confidence interval (CI) relative to the never-drinking group were calculated with adjustment for age and other potential confounding factors using the Cox proportional hazard model. Results— During an average follow-up of 6.4 years, 290 incident atrial fibrillation occurred. The higher incidence rate of atrial fibrillation was observed among participants with more than 69 g of ethanol drinking per week, compared with less than 69 g of ethanol drinking per week. On the other hand, light to moderate alcohol consumption was not associated with risk of atrial fibrillation. Compared with the never drinking group, the multivariable-adjusted HRs of past, light (<23 g), light moderate (23-46 g), moderate (46-69 g), and heavy (>69 g) drinking groups were 1.20 (95% CI, 0.61-2.35), 0.85 (95% CI, 0.57-1.27), 1.05 (95% CI, 0.63-1.75), 1.34 (95% CI, 0.78-2.32), and 2.92 (95% CI, 1.61-5.28), respectively. Conclusions— Heavy alcohol consumption was associated with the higher risk of atrial fibrillation, whereas there was no association of less than moderate alcohol consumption and atrial fibrillation.

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Abstract P237: Moderate and Heavy Alcohol Consumption Are Associated With Decreased Systolic Function After 8 Years of Follow-up

Circulation ◽

10.1161/circ.137.suppl_1.p237 ◽

2018 ◽

Vol 137 (suppl_1) ◽

Author(s):

Hanne Van Ballegooijen ◽

Petra J Elders ◽

Coen D Stehouwer ◽

Jacqueline M Dekker ◽

Joline Beulens

Keyword(s):

Alcohol Consumption ◽

Systolic Function ◽

Heavy Drinking ◽

Left Ventricular ◽

Volume Index ◽

Heavy Alcohol ◽

Heavy Drinkers ◽

Heavy Alcohol Consumption ◽

Excessive Alcohol

Introduction: Excessive alcohol consumption is an important risk factors for cardiovascular disease, however, the underlying mechanisms are not well understood. Hypothesis: We assessed the hypothesis whether alcohol consumption is prospectively associated with unfavorable measures of cardiac structure and function. Methods: We used data from the Hoorn Study, a population-based, prospective cohort study. Data on self-reported alcohol consumption were collected with a validated food frequency questionnaire in 2000/2001(baseline for the current analyses). Echocardiography was performed in 2000/2001 in 582 participants and in 2007/2009 in 339 participants. Participants were classified into 5 categories based on self-reported alcohol consumption (glasses per week): 0 (non-drinkers), 0- 3 (light-drinkers), ≥3-7 (light to moderate drinkers), ≥7-14 (moderate drinkers) and ≥14 (heavy drinkers). Light drinking was considered the reference group. We studied the association of alcohol consumption with echocardiographic measures after 8 years of follow-up using linear regression analyses, adjusting for potential confounders. Results: The mean age was 69.8±6.5 years and 50% was female. After 7.4±0.5 years follow-up, moderate and heavy alcohol consumption were associated with a decreased left ventricular ejection fraction of -5.1% (-8.7, -1.4) for moderate and -4.8% (-8.8, -0.8) for heavy drinkers (Table). Heavy drinking was also associated with a decrease in left atrial volume index: -3.9mL/m 2 (-7.6, -0.2). No longitudinal associations were found between alcohol consumption and left ventricular mass index. Conclusion: Both moderate and heavy drinking were associated with decreased systolic function after 8 years follow-up. The toxic effect of alcohol could lead to underfilling of the left atrium which could lead to lower systolic function. These findings may explain the increased cardiovascular risk among people with excessive alcohol use.

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Prospective Associations Between Alcohol Consumption and Psychological Well-being in Midlife

10.21203/rs.3.rs-743633/v1 ◽

2021 ◽

Author(s):

Marie Grønkjær ◽

Cathrine Lawaetz Wimmelmann ◽

Erik Lykke Mortensen ◽

Trine Flensborg-Madsen

Keyword(s):

Alcohol Consumption ◽

Binge Drinking ◽

Satisfaction With Life ◽

Well Being ◽

Psychological Well Being ◽

Men And Women ◽

Heavy Alcohol ◽

Alcohol Abstinence ◽

Heavy Alcohol Consumption

Abstract Background: Alcohol consumption potentially influences psychological well-being in beneficial and harmful ways, but prospective studies on the association show mixed results. Our main purpose was to examine prospective associations between alcohol consumption and psychological well-being in middle-aged men and women. Methods: The study sample included 4,148 middle-aged individuals (80% men) from the Copenhagen Aging and Midlife Biobank who reported their alcohol consumption (average weekly consumption and frequency of binge drinking) at baseline in 2004 or 2006 and reported their psychological well-being (satisfaction with life and vitality) at follow-up in 2009–2011. Analyses were adjusted for sociodemographic factors, lifestyle, social relations, and morbidity.Results: For satisfaction with life at follow-up, lower scores were observed in men and women who were alcohol abstinent at baseline as well as in men with heavy alcohol consumption compared with moderate alcohol consumption at baseline. Moreover, men with moderate frequency of binge drinking (1–3 times/month) at baseline had higher satisfaction with life scores at follow-up than men with less and more frequent binge drinking. In relation to vitality at follow-up, alcohol abstinence at baseline in men and women and heavy alcohol consumption at baseline in men were associated with lower scores compared with moderate alcohol consumption. Conclusions: Alcohol abstinence seems to be prospectively associated with adverse psychological well-being in men and women, while heavy alcohol consumption seems to be prospectively associated with adverse psychological well-being in men. Finally, an inverse u-shaped prospective association between binge drinking and life satisfaction was observed in men.

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Coronary deaths during Midsummer festival in Finland: miseries of long, light nights

European Journal of Epidemiology ◽

10.1007/s10654-021-00744-6 ◽

2021 ◽

Author(s):

Simo Näyhä

Keyword(s):

Coronary Heart Disease ◽

Heart Disease ◽

Alcohol Consumption ◽

Negative Binomial ◽

Negative Binomial Regression ◽

Adverse Consequence ◽

Heavy Alcohol ◽

Summer Peak ◽

Binomial Regression ◽

Heavy Alcohol Consumption

AbstractThis paper examines whether the anomalous summer peak in deaths from coronary heart disease (CHD) in Finland could be attributed to adverse effects of the Midsummer festival and alcohol consumption during the festival. Daily deaths from CHD and alcohol poisoning in Finland, 1961–2014, that occurred during the 7 days centering on Midsummer Day were analysed in relation to deaths during 14 to 4 days before and 4 to 14 after Midsummer Day. Daily counts of deaths from CHD among persons aged 35–64 years were regressed on days around the Midsummer period by negative binomial regression. Mortality from CHD was highest on Midsummer Day (RR 1.25 (95% confidence interval 1.12–1.31), one day after the peak in deaths from alcohol poisonings. RR for CHD on Midsummer Day was particulary high (RR = 1.43; 1.09–1.86) in the 2000s, 30% of deaths being attributable to that day. In conclusion, the anomalous and prominent summer peak in deaths from CHD in Finland is an adverse consequence of the Midsummer festival. The most likely underlying reason is heavy alcohol consumption during the festival period, especially on Midsummer Eve. In the 2000s, one third of deaths from CHD on Midsummer Day are preventable.

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Current Heavy Alcohol Consumption is Associated with Greater Cognitive Impairment in Older Adults

Alcoholism Clinical and Experimental Research ◽

10.1111/acer.13211 ◽

2016 ◽

Vol 40 (11) ◽

pp. 2435-2444 ◽

Cited By ~ 33

Author(s):

Adam J. Woods ◽

Eric C. Porges ◽

Vaughn E. Bryant ◽

Talia Seider ◽

Assawin Gongvatana ◽

...

Keyword(s):

Older Adults ◽

Cognitive Impairment ◽

Alcohol Consumption ◽

Heavy Alcohol ◽

Heavy Alcohol Consumption

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Protection of Gastrointestinal Mucosa from Acute Heavy Alcohol Consumption: The Effect of Berberine and Its Correlation with TLR2, 4/IL1β-TNFα Signaling

PLoS ONE ◽

10.1371/journal.pone.0134044 ◽

2015 ◽

Vol 10 (7) ◽

pp. e0134044 ◽

Cited By ~ 10

Author(s):

Xin-Pei Wang ◽

Fan Lei ◽

Feng Du ◽

Yu-Shuang Chai ◽

Jing-Fei Jiang ◽

...

Keyword(s):

Alcohol Consumption ◽

Gastrointestinal Mucosa ◽

Heavy Alcohol ◽

Heavy Alcohol Consumption

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Heavy alcohol consumption in children and adolescents: characteristics and gender differences

European Journal of Pediatrics ◽

10.1007/s00431-011-1448-z ◽

2011 ◽

Vol 170 (7) ◽

pp. 951-952

Author(s):

Sascha Meyer ◽

Sven Gottschling ◽

Ludwig Gortner

Keyword(s):

Gender Differences ◽

Alcohol Consumption ◽

Children And Adolescents ◽

Heavy Alcohol ◽

Heavy Alcohol Consumption ◽

And Gender

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THE INFLUENCE OF HEAVY ALCOHOL CONSUMPTION ON HIV INFECTION AND PROGRESSION

Journal of Biological System ◽

10.1142/s0218339009003083 ◽

2009 ◽

Vol 17 (04) ◽

pp. 685-712 ◽

Cited By ~ 8

Author(s):

G. THOMAS ◽

E. M. LUNGU

Keyword(s):

Alcohol Consumption ◽

Demographic Data ◽

African Region ◽

Heavy Alcohol ◽

Infected People ◽

Aids Epidemic ◽

Heavy Alcohol Consumption ◽

The Impact ◽

Global Population ◽

Hiv Aids

The Sub-Sahara African region is inhabited by only 11% of the global population, but is home to 67% of the total HIV infected people and accounts for more than 70% of global AIDS deaths. In this study, we construct a mathematical model to investigate the effect of heavy alcohol consumption on the transmission and progression of HIV/AIDS, and to assess the impact of heavy drinkers on HIV/AIDS related social and health problems such as TB case load and number of orphans. Using demographic data for Botswana, we have shown that if more HIV/AIDS individuals had been de-addicted from heavy alcohol consumption, the severity of the HIV/AIDS epidemic and the impact of HIV/AIDS on the number of TB cases and orphans would have been significantly less than is the case currently. The study points to the vital need for counseling and education about the evils of heavy alcohol consumption and for alcohol de-addiction programmes.

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