scholarly journals Causal relationship inference for a large-scale cellular network

2010 ◽  
Vol 26 (16) ◽  
pp. 2020-2028 ◽  
Author(s):  
Tong Zhou ◽  
Ya-Li Wang
2011 ◽  
Vol 23 (6) ◽  
pp. 1025-1026 ◽  
Author(s):  
Rajneesh K. Gaur

Pharmacovigilance is a resourceful process for monitoring adverse drug reactions. The lack of resources in developing countries makes it difficult to execute pharamcovigilance programs on a large scale. Therefore, the cellular technology based network, which has widespread access in the developing world, may be used as an inexpensive means of monitoring.


Author(s):  
Zhihan Fang ◽  
Yu Yang ◽  
Guang Yang ◽  
Yikuan Xian ◽  
Fan Zhang ◽  
...  

Data from the cellular network have been proved as one of the most promising way to understand large-scale human mobility for various ubiquitous computing applications due to the high penetration of cellphones and low collection cost. Existing mobility models driven by cellular network data suffer from sparse spatial-temporal observations because user locations are recorded with cellphone activities, e.g., calls, text, or internet access. In this paper, we design a human mobility recovery system called CellSense to take the sparse cellular billing data (CBR) as input and outputs dense continuous records to recover the sensing gap when using cellular networks as sensing systems to sense the human mobility. There is limited work on this kind of recovery systems at large scale because even though it is straightforward to design a recovery system based on regression models, it is very challenging to evaluate these models at large scale due to the lack of the ground truth data. In this paper, we explore a new opportunity based on the upgrade of cellular infrastructures to obtain cellular network signaling data as the ground truth data, which log the interaction between cellphones and cellular towers at signal levels (e.g., attaching, detaching, paging) even without billable activities. Based on the signaling data, we design a system CellSense for human mobility recovery by integrating collective mobility patterns with individual mobility modeling, which achieves the 35.3% improvement over the state-of-the-art models. The key application of our recovery model is to take regular sparse CBR data that a researcher already has, and to recover the missing data due to sensing gaps of CBR data to produce a dense cellular data for them to train a machine learning model for their use cases, e.g., next location prediction.


2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Luis F. Pedraza ◽  
Cesar A. Hernández ◽  
Danilo A. López

Radioelectric spectrum occupancy forecast has proven useful for the design of wireless systems able to harness spectrum opportunities like cognitive radio. This paper proposes the development of a model that identifies propagation losses and spectrum opportunities in a channel of a mobile cellular network for an urban environment using received signal power forecast. The proposed model integrates the Hata-Okumura (H-O) large-scale propagation model with a wavelet neural model. The model results, obtained through simulations, show that the wavelet neural model forecasts with a high degree of precision, which is consistent with the observed behavior in experiments carried out in wireless systems of this type.


2016 ◽  
Vol 20 (11) ◽  
pp. 2292-2295 ◽  
Author(s):  
Andreas Achtzehn ◽  
Janne Riihijarvi ◽  
Petri Mahonen

2018 ◽  
Vol 72 (6) ◽  
pp. 552-556
Author(s):  
Frank Gabel ◽  
Hendrik Jürges ◽  
Kai E Kruk ◽  
Stefan Listl

BackgroundDental diseases are among the most frequent diseases globally and tooth loss imposes a substantial burden on peoples' quality of life. Non-experimental evidence suggests that individuals with more children have more missing teeth than individuals with fewer children, but until now there is no causal evidence for or against this.MethodsUsing a Two-Stage Least Squares (2SLS) instrumental variables approach and large-scale cross-sectional data from the Survey of Health, Ageing, and Retirement in Europe (study sample: 34 843 non-institutionalised individuals aged 50+ from 14 European countries and Israel; data were collected in 2013), we investigated the causal relationship between the number of biological children and their parents’ number of missing natural teeth. Thereby, we exploited random natural variation in family size resulting from (i) the birth of multiples vs singletons, and (ii) the sex composition of the two first-born children (increased likelihood of a third child if the two first-born children have the same sex).Results2SLS regressions detected a strong causal relationship between the number of children and teeth for women but not for men when an additional birth occurred after the first two children had the same sex. Women then had an average of 4.27 (95% CI: 1.08 to 7.46) fewer teeth than women without an additional birth whose first two children had different sexes.ConclusionsThis study provides novel evidence for causal links between the number of children and the number of missing teeth. An additional birth might be detrimental to the mother’s but not the father’s oral health.


2018 ◽  
Author(s):  
Hon-Cheong So ◽  
Carlos Kwan-long Chau ◽  
Yu-ying Cheng ◽  
Pak C. Sham

AbstractBackgroundThe etiology of depression remains poorly understood. Changes in blood lipid levels were reported to be associated with depression and suicide, however study findings were mixed.MethodsWe performed a two-sample Mendelian randomization (MR) analysis to investigate the causal relationship between blood lipids and depression phenotypes, based on large-scale GWAS summary statistics (N=188,577/480,359 for lipid/depression traits respectively). Five depression-related phenotypes were included, namely major depressive disorder (MDD; from PGC), depressive symptoms (DS; from SSGAC), longest duration and number of episodes of low mood, and history of deliberate self-harm (DSH)/suicide (from UK Biobank). MR was conducted with inverse-variance weighted (MR-IVW), Egger and Generalized Summary-data-based MR(GSMR) methods.ResultsThere was consistent evidence that triglyceride (TG) is causally associated with DS (MR-IVW beta for one-SD increase in TG=0.0346, 95% CI=0.0114-0.0578), supported by MR-IVW and GSMR and multiple r2 clumping thresholds. We also observed relatively consistent associations of TG with DSH/suicide (MR-Egger OR= 2.514, CI: 1.579-4.003). There was moderate evidence for positive associations of TG with MDD and the number of episodes of low mood. For HDL-c, we observed moderate evidence for causal associations with DS and MDD. LDL-c and TC did not show robust causal relationships with depression phenotypes, except for weak evidence that LDL-c is inversely related to DSH/suicide. We did not detect significant associations when depression phenotypes were treated as exposures.ConclusionsThis study provides evidence to a causal relationship between TG, and to a lesser extent, altered cholesterol levels with depression phenotypes. Further studies on its mechanistic basis and the effects of lipid-lowering therapies are warranted.


2020 ◽  
pp. 1-13 ◽  
Author(s):  
Hon-Cheong So ◽  
Carlos Kwan-long Chau ◽  
Yu-ying Cheng ◽  
Pak C. Sham

Abstract Background The etiology of depression remains poorly understood. Changes in blood lipid levels were reported to be associated with depression and suicide, however study findings were mixed. Methods We performed a two-sample Mendelian randomisation (MR) analysis to investigate the causal relationship between blood lipids and depression phenotypes, based on large-scale GWAS summary statistics (N = 188 577/480 359 for lipid/depression traits respectively). Five depression-related phenotypes were included, namely major depression (MD; from PGC), depressive symptoms (DS; from SSGAC), longest duration and number of episodes of low mood, and history of deliberate self-harm (DSH)/suicide (from UK Biobank). MR was conducted with inverse-variance weighted (MR-IVW), Egger and Generalised Summary-data-based MR (GSMR) methods. Results There was consistent evidence that triglyceride (TG) is causally associated with DS (MR-IVW β for one-s.d. increase in TG = 0.0346, 95% CI 0.0114–0.0578), supported by MR-IVW and GSMR and multiple r2 clumping thresholds. We also observed relatively consistent associations of TG with DSH/suicide (MR-Egger OR = 2.514, CI 1.579–4.003). There was moderate evidence for positive associations of TG with MD and the number of episodes of low mood. For HDL-c, we observed moderate evidence for causal associations with DS and MD. LDL-c and TC did not show robust causal relationships with depression phenotypes, except for weak evidence that LDL-c is inversely related to DSH/suicide. We did not detect significant associations when depression phenotypes were treated as exposures. Conclusions This study provides evidence to a causal relationship between TG, and to a lesser extent, altered cholesterol levels with depression phenotypes. Further studies on its mechanistic basis and the effects of lipid-lowering therapies are warranted.


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