scholarly journals Relationship Between Dietary Lutein and Cognition in an Older Adult Population (P14-030-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Krystle Zuniga ◽  
Alexandria Turner ◽  
Nicholas Bishop
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Older Adult ◽  
Verbal Memory ◽  
Adult Population ◽  
Panel Study ◽  
Community Dwelling ◽  
Leafy Vegetables ◽  
Cognitive Domain ◽  
Word Recall

Abstract Objectives The dietary carotenoid lutein accumulates in the brain, and lutein supplementation has been demonstrated to improve cognitive function in older adults. The purpose of the study was to examine the association between dietary lutein intake and cognitive function in a recent and representative sample of the older adult U.S. population. Additionally, we aimed to identify the major contributors to dietary lutein intake in older adults. Methods Observations were drawn from the 2012 Health and Retirement Study (HRS), a nationally-representative panel study of older U.S. adults, and the 2013 Health Care and Nutrition Study (HCNS), which assessed dietary intake via food frequency questionnaire in a subsample of HRS respondents. The analytic sample included 7045 respondents age 50 and older. Cognitive function was evaluated on the cognitive domain of episodic verbal memory, assessed using immediate word recall (IWR) and delayed word recall (DWR). Quartiles of lutein intake were calculated then used to compare IWR and DWR scores in 2012. Descriptive statistics and bivariate comparisons were adjusted for the complex survey design of the HRS and HCNS with results representative of community-dwelling older Americans in 2013. Results The average age of the sample was 65.6 ± 10.3 years old. Leafy vegetables, cruciferous vegetables, dark yellow vegetables, eggs, fruit and other vegetables were significant predictors of dietary lutein intake. Lutein intake was significantly different between quartiles (P < 0.001) with lutein intakes of 720 ± 231 ug/day (Q1), 1468 ± 229 ug/day (Q2), 2394 ± 324 ug/day (Q3), and 5632 ± 3029 ug/day (Q4). Quartiles 3 and 4 had significantly higher IWR and DWR scores than quartiles 1 and 2 (P < 0.001). Conclusions Older adults may benefit from higher lutein intake through consumption of various vegetables, fruits, and eggs, as lutein may specifically protect episodic memory. Further research is needed to identify the mechanism of lutein's cognitive benefits. Funding Sources American Egg Board/Egg Nutrition Center.

Abstract 22: Visit-to-Visit Variability in Blood Pressure is Related to Late-Life Cognitive Decline

Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Bo Qin ◽  
Anthony J Viera ◽  
Linda S Adair ◽  
Brenda L Plassman ◽  
Lloyd J Edwards ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Older Adults ◽  
Cognitive Function ◽  
Cognitive Decline ◽  
Verbal Memory ◽  
Repeated Measures ◽  
Community Dwelling ◽  
Cognitive Testing ◽  
Cognitive Test ◽  
Nutrition Survey

Introduction: Recent studies suggest higher visit-to-visit variability of blood pressure (BP) is associated with worse cognitive function, but evidence based on longitudinal cognitive testing has not been reported. Hypothesis: We assessed the hypothesis that higher visit-to-visit variability in BP, but not mean BP, would be associated with faster decline in cognitive function among community-dwelling older adults. Methods: This prospective cohort study comprised 1213 adults who had two or more waves of BP measurements as part of the China Health and Nutrition Survey from 1991, up to their first cognitive tests, and completed a cognitive screening test at two or more waves in 1997, 2000 or 2004. Mean (SD) age at first cognitive test was 64 (6) y. Outcomes were repeated measures of global cognitive scores (baseline mean ± SD: 19 ± 6 points), standardized composite cognitive and verbal memory scores (standardized units [SU]). Visit-to visit BP variability was expressed as the standard deviation [SD] or as the variation independent of mean (SD/mean^x, with x derived from curve fitting) in BP measures obtained at a mean interval of 3.6 years. Multivariable-adjusted linear mixed-effects models were used to determine the association of changes in cognitive scores with visit-to visit BP variability. Results: Higher visit-to-visit variability in systolic BP, but not mean systolic BP, was associated with a faster decline of cognitive function (adjusted mean difference [95% CI] for high vs. low tertile of SD in variability (Figure): global score -0.23 points/y [-0.41 to -0.04], composite scores -0.029 SU/y [-0.056 to -0.002] and verbal memory -0.044 SU/y [-0.075 to -0.012]). Higher visit-to-visit variability in diastolic BP was associated with a faster decline of global cognitive function only among adults 55-64 years, independent of mean diastolic BP. Conclusion: Higher long-term BP visit-to-visit variability predicted a faster rate of cognitive decline among older adults.

Dietary lutein and zeaxanthin are associated with working memory in an older population

2020 ◽  
pp. 1-8 ◽  
Author(s):  
Krystle E Zuniga ◽  
Nicholas J Bishop ◽  
Alexandria S Turner
Keyword(s):  
Older Adults ◽  
Panel Study ◽  
Leafy Vegetables ◽  
Word Recall ◽  
Cross Sectional ◽  
Nutrition Study ◽  
Nationally Representative ◽  
Sectional Analysis ◽  
Analytic Models ◽  
Retirement Study

Abstract Objective: The purpose of the study was to examine the association between dietary lutein and zeaxanthin (L + Z) intake and immediate word recall (IWR) and delayed word recall (DWR), and to identify the major contributors to dietary L + Z intake in a recent and representative sample of the older US population. Design: In this cross-sectional analysis, multivariate path analytic models estimated the association between L + Z consumption and cognitive performance while adjusting for covariates. Setting: Observations were drawn from the 2014 Health and Retirement Study, a nationally representative panel study of older US adults, and the 2013 Health Care and Nutrition Study, which assessed dietary intake via FFQ in a subsample of respondents. Participants: The analytic sample included 6390 respondents aged ≥50 years. Results: L + Z intake was 2·44 ± 2·32 mg/d on average, and L + Z intake differed significantly across quartiles (P < 0·001). For example, average L + Z intake in Q1 was 0·74 ± 0·23 mg/d and in Q4 was 5·46 ± 2·88 mg/d. In covariate adjusted models, older adults in the highest quartiles of L + Z intake had significantly greater IWR and DWR scores than those in the lowest quartile. Leafy vegetables, cruciferous vegetables, dark yellow vegetables, fish and seafood, legumes, eggs and fruit were significant and meaningful predictors of dietary L + Z intake. Conclusion: A high consumption of vegetables, fish and seafood, legumes, eggs and fruit is associated with a higher intake of L + Z and greater word recall among older adults.

104 Sociodemographic, Cognitive & Physical Function Characteristics among Older Adult Fallers with and without Cognitive Frailty: Preliminary Results

2019 ◽  
Vol 48 (Supplement_4) ◽  
pp. iv18-iv27
Author(s):  
Resshaya Murukesu ◽  
Devinder Kaur Ajit Singh ◽  
Suzana Shahar ◽  
Ponnusamy Subramaniam
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Physical Function ◽  
Older Adult ◽  
Verbal Learning ◽  
Community Dwelling ◽  
Step Test ◽  
Medical Attention ◽  
Categorical Variables ◽  
Cognitive Frailty

Abstract Introduction Older adults with frailty and cognitive impairment are more susceptible to falls. The risk factor of falls and faller profiles among older adults in general has been established. However, information regarding potential risk factors and faller patterns among older adults with cognitive frailty is limited. Objective To examine the sociodemographic, cognitive and physical function characteristics of fallers with and without cognitive frailty. Methods A total of 133 community dwelling older adults aged 60 years and above were screened at three older adult activity centres in Kuala Lumpur. Sociodemographic details were obtained via interview. Cognitive Frailty was identified using the Clinical Dementia Rating Scale and Fried Frailty Index. Cognitive function was assessed using the Mini Mental State Examination (MMSE), Digit Span (DS) test and Ray Auditory Verbal Learning Test (RAVLT). The Senior Fitness test was used to asses physical function. Characteristics of falls were documented using a self-administered questionnaire. Data was descriptively analysed; independent T-test was used for continuous variables and chi-square test was used for categorical variables. Results Prevalence of falls was 21.1% (n=28). Within fallers, 42.9% (n=12) were cognitively frail and 57.1% (n=16) were not. Fallers with cognitive frailty were significantly older (mean age = 72.31±5.29) (p&lt;0.001), had lower MMSE scores (p&lt;0.01), lower 2 Minute Step test scores (p&lt;0.001) and lower Lawton Instrumental Activities of Daily Living scores (p&lt;0.05). Descriptively, fallers with cognitive frailty were mostly recurrent fallers (67%), sustained falls outdoors due to ‘slip and fall’ and majority sought medical attention after the fall(s). Conclusion Fallers with cognitive frailty were older and had lower physical and cognitive function as compared to those without. There is a need to further understand the relationship between falls and cognitive frailty in order to provide holistic fall prevention and management strategies. Acknowledgement of grant UKM(DCP-2017-002/2) and Ministry of Higher Education(LRGS/BU/2012/UKM-UKM/K/01).

scholarly journals The relationship between adiposity and cognitive function in a large community-dwelling population: data from the Trinity Ulster Department of Agriculture (TUDA) ageing cohort study

2018 ◽  
Vol 120 (5) ◽  
pp. 517-527 ◽  
Author(s):  
Ontefetse Ntlholang ◽  
Kevin McCarroll ◽  
Eamon Laird ◽  
Anne M. Molloy ◽  
Mary Ward ◽  
...  
Keyword(s):  
Older Adults ◽  
Cohort Study ◽  
Cognitive Function ◽  
Community Dwelling ◽  
Cognitive Domain ◽  
Linear Regression Models ◽  
Department Of Agriculture ◽  
Negatively Associated ◽  
The Relationship ◽  
The Trinity

AbstractPrevious reports investigating adiposity and cognitive function in the population allude to a negative association, although the relationship in older adults is unclear. The aim of this study was to investigate the association of adiposity (BMI and waist:hip ratio (WHR)) with cognitive function in community-dwelling older adults (≥60 years). Participants included 5186 adults from the Trinity Ulster Department of Agriculture ageing cohort study. Neuropsychological assessment measures included the Mini-Mental State Examination (MMSE), Frontal Assessment Battery (FAB) and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). Multi-variable linear regression models were used to assess the association between adiposity and cognitive function adjusting for insulin resistance, inflammation and cerebrovascular disease. The mean ages were 80·3 (sd6·7), 71·0 (sd7·3) and 70·2 (sd6·3) years on the cognitive, bone and hypertensive cohorts, respectively. In the cognitive cohort, BMI was positively associated with immediate and delay memory, visuospatial/constructional ability, language and MMSE, and negatively with FAB (log-transformed), whereas WHR was negatively associated with attention. In the bone cohort, BMI was not associated with any cognitive domain, whereas WHR was negatively associated with visuospatial/constructional ability, attention and MMSE. In the hypertensive cohort, BMI was not associated with any cognitive domain, whereas WHR was negatively associated with immediate and delayed memory, visuospatial/constructional ability, language and MMSE and positively with FAB (log-transformed). In the cognitive and bone cohorts, the association of WHR and attention disappeared by further controlling for C-reactive protein and HbA1C. In this study of older adults, central adiposity was a stronger predictor of poor cognitive performance than BMI. Older adults could benefit from targeted public health strategies aimed at reducing obesity and obeseogenic risk factors to avoid/prevent/slow cognitive dysfunction.

Association between Skin Conditions and Depressive Disorders in Community-Dwelling Older Adults

2014 ◽  
Vol 18 (4) ◽  
pp. 256-264 ◽  
Author(s):  
Samantha Gontijo Guerra ◽  
Michel Préville ◽  
Helen-Maria Vasiliadis ◽  
Djamal Berbiche
Keyword(s):  
Older Adults ◽  
Older Adult ◽  
Depressive Disorders ◽  
Adult Population ◽  
Community Sample ◽  
The Elderly ◽  
Population Based ◽  
Community Dwelling ◽  
Cross Sectional ◽  
Skin Conditions

Background: Depression is frequently observed in dermatologic patients. However, the association between depressive disorders and skin conditions has rarely been explored through population-based studies, especially within older-adult populations. Objective: To test this association in a representative sample of an older-adult population. Methods: Data came from the Survey on the Health of the Elderly (Enquête sur la Santé des Aînés [ESA]), a longitudinal survey conducted in Quebec among 2,811 older adults. Cross-lagged panel models were used to simultaneously examine cross-sectional and longitudinal relationships between the presence of skin conditions and depressive disorders. Results: The prevalence of skin conditions was 13%, and the prevalence of depressive disorders among participants presenting with skin conditions was 11%. Our results indicated significant cross-sectional correlation ( ζ = 0.20) between skin conditions and depressive disorders, but no longitudinal association was observed. Conclusion: Our results reinforce the hypothesis that skin conditions and depressive disorders are concurrently associated in older adults. However, no evidence of the predictive effect of skin problems on depression (and vice versa) was found in our community sample. Despite the deleterious effect of the coexistence of these problems in older adults, studies are lacking. This article highlights the importance of this issue and emphasizes the need for further research on this topic.

scholarly journals Associations Between Cognitive Function, Balance, and Mobility in Community-Dwelling Older Adults With COPD

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 230-230
Author(s):  
Shweta Gore ◽  
Jennifer Blackwood ◽  
Tyler Ziccardi
Keyword(s):  
Older Adults ◽  
Executive Function ◽  
Cognitive Function ◽  
Gait Speed ◽  
Community Dwelling ◽  
Word Recall ◽  
Measure Data ◽  
Control Group ◽  
Chronic Obstructive ◽  
Delayed Recall

Abstract Older adults with chronic obstructive pulmonary disease (COPD) are at risk for physical and cognitive impairment. Cognitive function is associated with falls in older adults however it is unknown if a relationship exists between cognitive function and falls in COPD. The aim of this study was to examine the relationships between cognitive function and balance and mobility in older adults with COPD. A secondary analysis was performed using data from the 2010 wave of the Health and Retirement Study (HRS) (N=4051). Cognitive (immediate and delayed recall, executive function) and physical (gait speed, tandem balance time) measure data was extracted from older adults with COPD (N=382) and an age matched control group without COPD (N=382) who met inclusion/exclusion criteria. Multivariate linear regression modeling was performed to examine associations between cognitive function and mobility or balance while controlling for age, gender, BMI, grip strength, and education. We found that in COPD, immediate word recall, delayed word recall, orientation, and executive function (β ranging from 0.004-0.02) were significantly associated with gait speed while only delayed word recall (β = 0.122, p &lt; .05) was associated with tandem balance. These same associations did not exist in those without COPD. In older adults with COPD, cognitive function is associated with balance and mobility. Screening for cognitive function, specifically delayed recall, should be a part of the management of falls in this population.

scholarly journals Self-management of social well-being in a cross-sectional study among community-dwelling older adults: The added value of digital participation

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mariska MJ Scheffer ◽  
Juliane Menting ◽  
Hennie R Boeije
Keyword(s):  
Older Adults ◽  
Adult Population ◽  
Panel Study ◽  
Well Being ◽  
Community Dwelling ◽  
Internet Usage ◽  
Added Value ◽  
Self Management ◽  
Cross Sectional ◽  
Community Dwelling Older Adults

Abstract Background This study aimed to examine associations between self-management abilities and digital participation among community-dwelling older adults with chronic conditions in the Netherlands. Methods The study utilized a cross-sectional design. Community-dwelling older adults were sampled from a Dutch nationwide panel study performed in October and November of 2019. We selected all adults of 65 years and above who had one or more chronic diseases (n = 1,656). Self-management was measured by six abilities (e.g., investing in resources for long-term benefits and taking care of a variety of resources), whereas digital participation was estimated with the frequency of four social internet uses (e.g., using social network websites and calling digitally). Results When predicting self-management abilities from digital participation, hierarchical multiple regression analysis determined statistically significant and positive relationships, in particular for e-mailing (β = 0.21; p < .001) and meeting new people online (β = 0.07; p < .05). Correlation analyses showed that highest associations were found between internet usage and the self-management abilities ‘taking initiative’ (r = .23; p < .001) and ‘being self-efficacious’ (r = .21; p < .001). Moreover, the study confirmed that higher age (β = -0.13; p < .001) and increased severity of disability (β = -0.12; p < .01) negatively impact abilities for self-management. Conclusions These findings suggest that internet usage and self-management abilities are positively related in the older adult population. Further research should be undertaken to examine the links between self-management abilities and digital participation more closely.

Medication Adherence in New Zealand Older Adults: Effects of an External Cognitive Support

2005 ◽  
Vol 11 (2) ◽  
pp. 69-83
Author(s):  
June Greyvenstein ◽  
Nikolaos Kazantzis ◽  
Nancy A. Pachana
Keyword(s):  
Older Adults ◽  
New Zealand ◽  
Medication Adherence ◽  
Older Adult ◽  
Controlled Trial ◽  
Adult Population ◽  
Community Dwelling ◽  
Cognitive Support ◽  
Present Sample ◽  
Randomised Controlled

Pharmacotherapy is the most frequently used treatment modality among the older adult population. Consequently, medication adherence represents an important treatment consideration. The present study was conducted to assess the extent of medication adherence in the New Zealand sample, and evaluate the effectiveness of an external cognitive support in a sample of 50 community-dwelling older adults (M = 70.70, Mdn = 72.00, SD = 8.12). A randomised controlled trial to compare the usual medication practice with a medication calendar was conducted. The present sample had high levels of medication adherence, with high adherence measured on an adherence ratio 97% (range 82% to 109%), and low rate of medication errors (19 errors). There were no significant differences in medication adherence between intervention and control groups (ps > .05). However, consistent with prior research, there was some evidence to suggest that female participants were less compliant and made more errors than male participants. Further research on larger more representative older adult samples is warranted.

scholarly journals No clear relationship between antihypertensive class and cognitive function over 12 months in a cohort study of community-dwelling adults aged 80 and over

2019 ◽  
Vol 10 ◽  
pp. 204062231882084 ◽  
Author(s):  
Ruth Peters
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Adult Population ◽  
Community Dwelling ◽  
Channel Blockers ◽  
80 And Over ◽  
Aged 80 And Over ◽  
Increased Risk ◽  
Older Adult Population ◽  
The Impact

Background: Hypertension is prevalent in older adults. Hypertension has also been associated with an increased risk of cognitive decline. However, evidence relating to the impact of antihypertensive use is mixed. Calcium-channel blockers (CCB) have been suggested as the most beneficial class of antihypertensive for protection of cognition in older adults, however, to date, there have been no cohort studies designed to examine this. Methods: Community-dwelling treated hypertensive adults aged 80 and over were recruited from general practice sites and followed for 1 year. Cognitive function was assessed at baseline and 12 months using the modified Mini-Mental State Exam (3MS). Regression was used to examine the association between 12-month exposure to antihypertensive class and change in cognitive function. Results: A total of 292 participants completed the study. Mean change in 3MS score was a rise of 0.53 [standard deviation (SD) 4.7] 3MS points in those taking CCBs ( n = 135) compared with a drop of 0.09 (SD 5.1) in those without ( n = 157) p = 0.28. There was no relationship between CCBs or between any antihypertensive class and change in cognitive function over 1 year. Additional analyses using a clinically meaningful fall of 5 or more 3MS points showed similar results. Conclusion: In a hypertensive community-dwelling older adult population treated with antihypertensives, there was no evidence that CCBs were protective of cognitive function over a 12-month exposure. If a protective effect is present, it may be small or require a longer treatment period. Larger longer studies are required for confirmation.

Alternative methods of pain management for the older adult population: Review of topical pain medications

2015 ◽  
Vol 5 (3) ◽  
pp. 109-122
Author(s):  
Candice Tavares
Keyword(s):  
Older Adults ◽  
Pain Management ◽  
Older Adult ◽  
Adult Population ◽  
The Elderly ◽  
The United States ◽  
Community Dwelling ◽  
Alternative Methods ◽  
Pain Medications ◽  
Older Adult Population

Abstract The older adult population is one of the fastest growing age groups in the United States. As this population continues to expand, determining the safest way to provide pain management has become increasingly important. More than 50% of community-dwelling older adults experience pain on a daily basis, and up to 83% of those in assisted living facilities experience persistent pain. Pain is exceedingly challenging to treat safely and effectively in the elderly because of the physiologic changes that occur as people age. In addition, many nonnarcotic medications with analgesic properties are listed in both the 2012 American Geriatrics Society Beers Criteria for Potentially Inappropriate Medication Use in Older Adults and the Pharmacy Quality Alliance high-risk medications lists. An approach to the growing challenge of managing pain in the elderly that is gaining popularity among community-dwelling patients is the use of topical pain medications. The goal of this article is to review some of the available literature regarding the use of various topical analgesics alone or in combination, and to discuss their known or theoretical mechanisms of peripheral pain modulation. Commercially available or compounded topical pain medications may be used to replace or augment doses of oral medications in an effort to decrease the risk of adverse drug events for older adult patients. When prescribing topical pain medications physicians should consider the nature of the pain targeted, the type of analgesia expected from each ingredient, the potential for systemic absorption, and related side effects.

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