New insights from the application of the FAbry STabilization indEX in a large population of Fabry cases

Psyllium hydrophillic mucilloid is a natural gelling fiber consumed by a large population of our society. It is used as a bulk-producing laxative and in the treatment of gastrointestinal disorders such as “Irritable Bowel Syndrome”. The literature pertaining to the ultrastructural effects of this agent is sparse.This study documents morphological changes induced by psyllium. Animals fed a diet containing 2% psyllium for four weeks were subsequently sacrificed and processed for scanning and transmission electron microscopy. The colon contained fecal material combined with psyllium which conformed to the contour of the luminal surface. This mixture formed surface replicas of the intestinal mucosa. These replicas and their related colonic sites were processed for morphologic analysis.

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Cardiovascular disease and risk factors in persons with type 2 diabetes diagnosed in a large population screening: The Nord-Trondelag Diabetes Study, Norway

Journal of Internal Medicine ◽

10.1046/j.1365-2796.2000.00759.x ◽

2000 ◽

Vol 248 (6) ◽

pp. 492-500 ◽

Cited By ~ 16

Author(s):

T. Claudi ◽

K. Midthjell ◽

J. Holmen ◽

K. Fougner ◽

O. Kruger ◽

...

Keyword(s):

Risk Factors ◽

Type 2 Diabetes ◽

Cardiovascular Disease ◽

Large Population ◽

Population Screening

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Non-invasive ultrasound-based imaging of atherosclerosis

VASA ◽

10.1024/0301-1526/a000747 ◽

2019 ◽

Vol 48 (2) ◽

pp. 126-133 ◽

Cited By ~ 3

Author(s):

Mathias Kaspar ◽

Iris Baumgartner ◽

Daniel Staub ◽

Heinz Drexel ◽

Christoph Thalhammer

Keyword(s):

Large Population ◽

Treatment Strategies ◽

Intima Media Thickness ◽

Scientific Work ◽

Flow Mediated Dilation ◽

Non Invasive ◽

Grey Scale ◽

Current Review ◽

Appropriate Treatment ◽

Contrast Enhanced

Abstract. Early detection of vascular damage in atherosclerosis and accurate assessment of cardiovascular risk factors are the basis for appropriate treatment strategies in cardiovascular medicine. The current review focuses on non-invasive ultrasound-based methods for imaging of atherosclerosis. Endothelial dysfunction is an accepted early manifestation of atherosclerosis. The most widely used technique to study endothelial function is non-invasive, flow-mediated dilation of the brachial artery under high-resolution ultrasound imaging. Although an increased intima-media thickness value is associated with future cardiovascular events in several large population studies, systematic use is not recommended in clinical practice for risk assessment of individual persons. Carotid plaque analysis with grey-scale median, 3-D ultrasound or contrast-enhanced ultrasound are promising techniques for further scientific work in prevention and therapy of generalized atherosclerosis.

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The Hierarchical Model of Exercise Dependence

Journal of Individual Differences ◽

10.1027/1614-0001/a000172 ◽

2015 ◽

Vol 36 (4) ◽

pp. 247-257 ◽

Cited By ~ 1

Author(s):

Gayatri Kotbagi ◽

Laurence Kern ◽

Lucia Romo ◽

Ramesh Pathare

Keyword(s):

Factor Analysis ◽

Confirmatory Factor Analysis ◽

Physical Exercise ◽

Exploratory Factor Analysis ◽

Convergent Validity ◽

Large Population ◽

Assessment Tools ◽

Negative Consequences ◽

Confirmatory Factor ◽

Preliminary Version

Abstract. Physical exercise when done excessively may have negative consequences on physical and psychological wellbeing. There exist many scales to measure this phenomenon. The purpose of this article is to create a scale measuring the problematic practice of physical exercise (PPPE Scale) by combining two assessment tools already existing in the field of exercise dependency but anchored in different approaches (EDS-R and EDQ). This research consists of three studies carried out on three independent sample populations. The first study (N = 341) tested the construct validity (exploratory factor analysis); the second study (N = 195) tested the structural validity (confirmatory factor analysis) and the third study (N = 104) tested the convergent validity (correlations) of the preliminary version of the PPPE scale. Exploratory factor analysis identified six distinct dimensions associated with exercise dependency. Furthermore, confirmatory factor analysis validated a second order model consisting of 25 items with six dimensions and four sub-dimensions. The convergent validity of this scale with other constructs (GLTEQ, EAT26, and The Big Five Inventory [BFI]) is satisfactory. The preliminary version of the PPPE must be administered to a large population to refine its psychometric properties and develop scoring norms.

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