Transport of Beta-Carotene in Serum of Individuals with Carotenemia

Abstract We studied distribution of carotene in the various serum lipid fractions of carotenemic and noncarotenemic individuals. We found that the amount of carotene in each lipoprotein fraction is increased in the serum from carotenemic individuals, but that the relative increase is significant only in the low-density lipoprotein and high-density lipoprotein fractions. There was no significant difference between the cholesterol concentrations of each fraction of the carotenemic individuals' and noncarotenemic individuals' sera, indicating that serum betalipoprotein is not increased in carotenemia.

Download Full-text

Alterations of Lipid profile levels in 7,12-Dimethylbenz(a)anthracene induced ulcerative colitis rat model.

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2017.v10i4.16858 ◽

2017 ◽

Vol 10 (4) ◽

pp. 352

Author(s):

Geetha Palaniswamy ◽

Lakshman Kumar B ◽

Indra U ◽

Pavithra Sheetal B

Keyword(s):

Ulcerative Colitis ◽

High Density Lipoprotein ◽

Lipid Profile ◽

Total Cholesterol ◽

Intestinal Inflammation ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

High Density ◽

Low Density ◽

Significant Difference

Objective: Ulcerative colitis is a type of inflammatory bowel disease is a chronic gastrointestinal disorder characterized by intestinal inflammation and mucosal tissue damage. We examined the lipid profile levels in murine model of 7,12 Dimethylbenz(a)anthracene induced ulcerative colitis.Methods: Serum was separated from whole blood and was used to determine the lipid profile such as total cholesterol (TC), phospholipids (PL), triglycerides (TG), free fatty acids, high density lipoprotein (HDL-C) and low density lipoprotein (HDL-C).Results: Ulcerative colitis rats exhibit low level of low density lipoprotein cholesterol and total cholesterol. No significant difference was observed in high density lipoprotein and triglycerides and significant difference was observed in phospholipids and free fatty acid serum levels. This communication highlights the lipid profile that occurs in ulcerative colitis.Conclusion: This study, thus, provides valuable information about the disturbances in the lipids and lipoproteins occur in ulcerative colitis.Keywords: Ulcerative colitis, 7,12-Dimethylbenz(a)anthracene, Lipoprotein, Low-density lipoprotein, Phospholipids.

Download Full-text

Perbandingan Kadar Low Density Lipoprotein dan High Density Lipoprotein Antara Akseptor KB Pil Kombinasi Dengan Depo Medroksiprogesteron Asetat

Jurnal Ilmiah Universitas Batanghari Jambi ◽

10.33087/jiubj.v19i1.538 ◽

2019 ◽

Vol 19 (1) ◽

pp. 47

Author(s):

Helti Lestari Sitinjak ◽

Rauza Sukma Rita ◽

Yusrawati Yusrawati

Keyword(s):

High Density Lipoprotein ◽

Sampling Method ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

High Density ◽

Comparative Approach ◽

Low Density ◽

Weight Changes ◽

Contraceptive Pill ◽

Significant Difference

More than six million women worldwide use contraceptive injection and the popular contraceptive method used is contraceptive pill. Combined pill contraceptives have side effects, which are increased triglyceride and total cholesterol levels and changes in carbohydrate metabolism while the DMPA is irregular menstruation/amenorrhea, weight changes and lipid changes.This research is an observational with Cross Sectional Comparative approach to 36 combination pill acceptor and 36 DMPA acceptor. This study was conducted ini the area of Andalas and Lubuk Buaya Health Center. The sampling method used in this research was simple random sampling method. The analysis was used T-Independent test. The results showed that Low Density Lipoprotein levels DMPA (63,97 ± 12,75 mg/dl) vs combined contraceptive pill (89,66 ± 28,39 mg/dl) p = 0,25 and High Density Lipoprotein levels DMPA (63,97± 12,75 mg/dl) vs combined contraceptive pill (60,06 ± 15,57 mg/dl), p = 0,25. Results of this study concluded that there was significant difference in average of Low Density Lipoprotein and High Density Lipoprotein levels in the combined contraceptive pill and Medroxy Progesteron Acetate Depot acceptor but statistically the difference was no significant.

Download Full-text

Use of the TLX ultracentrifuge for the isolation of different density lipoproteins and effects of freeze/thawing of human plasma before ultracentrifugation

Clinical Chemistry and Laboratory Medicine (CCLM) ◽

10.1515/cclm.2008.254 ◽

2008 ◽

Vol 46 (9) ◽

Cited By ~ 4

Author(s):

Valentine Charlton-Menys ◽

Jelena Chobotova ◽

Paul N. Durrington

Keyword(s):

High Density Lipoprotein ◽

High Density Lipoprotein Cholesterol ◽

Apolipoprotein B ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

High Density ◽

Low Density ◽

Small Dense Ldl ◽

Significant Difference ◽

Fresh Plasma

Abstract: Isolation of different density lipoproteins by ultracentrifugation can require lengthy centrifugation times and freeze/thawing of plasma may influence recovery.: We isolated a range of lipoproteins using a preparative ultracentrifuge and the TLX micro-ultracentrifuge and determined the effect of freeze/thawing of plasma beforehand.: In fresh plasma, there was no significant difference in results for small-dense low-density lipoprotein apolipoprotein B (LDL apoB) (density >1.044 g/mL) or cholesterol at density >1.006 g/mL. Freeze/thawing had no effect on closely correlated results for small-dense LDL apoB (r=0.85; p<0.0001) or high-density lipoprotein (r=0.93; p<0.0001).: The TLX micro-ultracentrifuge is a reliable alternative to the preparative ultracentrifuge and freeze/thawing has only a small effect on small-dense LDL apoB or high-density lipoprotein cholesterol.Clin Chem Lab Med 2008;46:1285–8.

Download Full-text