Detection of pentazocine and tripelennamine in urine.

1981 ◽  
Vol 27 (1) ◽  
pp. 10-13 ◽  
Author(s):  
R W Reid ◽  
C M Gerbeck
Keyword(s):  
Gas Chromatography ◽  
Drug Abuse ◽  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Chemical Ionization ◽  
Mass Spectrometric ◽  
Routine Screening ◽  
Ionization Mode ◽  
Layer Chromatography ◽  
Chromatographic Mass

Abstract Pentazocine and tripelennamine can be identified in urine as a part of routine screening for drug abuse. Pentazocine, pentazocine hydrate, and tripelennamine can be detected by thin-layer chromatography of chloroform/isopropanol extracts of heat- and acid-hydrolyzed urine. Gas chromatography is used for confirmation. Gas chromatographic/mass spectrometric studies (chemical ionization mode) show that such extracts contain major molecular (M+) ions of m/e 256, 286, and 304, indicating the presence of tripelennamine, pentazocine, and pentazocine hydrate, respectively.

Gas Chromatographic-Mass Spectrometric Detection and Quantitation of Lincomycin in Animal Feedingstuffs

1984 ◽  
Vol 67 (3) ◽  
pp. 582-588
Author(s):  
Cecil H McMurray ◽  
W John Blanchflower ◽  
Desmond A Rice
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Retention Time ◽  
Coefficient Of Variation ◽  
Chemical Ionization ◽  
Mass Spectrometric ◽  
Gas Chromatography Mass Spectrometry ◽  
Ionization Mode ◽  
Main Fragment ◽  
Chromatographic Mass

Abstract A substantially Improved assay was developed for lincomycin A in animal feedingstuffs. The assay allows unambiguous quantitation of at least 0.1 ppm in feed. Lincomycin B did not interfere because of differences in both retention time and mass of the main fragment ion in electron impact (EI) spectra. The assay using single ion monitoring with EI detection would not discriminate between lincomycin A and clindamycin. The presence of the latter was easily confirmed by using gas chromatography-mass spectrometry in the chemical ionization mode. The assay for lincomycin A was linear in the range 0–40 ng applied to the gas chromatographic column. The recovery was 93.4 ± 4.2% at 1 and 5 ppm and 86.2 ± 5.5% at 0.1 ppm in feed. The coefficient of variation of the assay was 4.8% at both 1 and 5 ppm, and was 6.43% at 0.1 ppm.

scholarly journals Rapid Identification of Psychopharmacologic Agents in Cases of Drug Abuse

1972 ◽  
Vol 18 (5) ◽  
pp. 405-409 ◽  
Author(s):  
David Sohn ◽  
Julius Simon
Keyword(s):  
Gas Chromatography ◽  
Drug Abuse ◽  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Drug Overdose ◽  
Rapid Identification ◽  
Suspected Drug ◽  
Toxic Agents ◽  
Layer Chromatography

Abstract When a patient is hospitalized in coma with suspected drug overdose, rapid identification of psychopharmacologic or toxic agents is essential. Methods for excluding other common toxic agents are indicated. Psychomimetic drugs that should be identified are enumerated. Screening by thin-layer chromatography is suggested as the method of choice, with confirmation or quantification by gas chromatography. Appropriate references to current methodology are appended.

Thin-layer chromatography and gas chromatography-mass spectrometry examination of shoe materials from patients with shoe dermatitis

2015 ◽  
Vol 72 (4) ◽  
pp. 248-252 ◽  
Author(s):  
Sri A. Febriana ◽  
Erik Zimerson ◽  
Cecilia Svedman ◽  
Winarto Haryadi ◽  
Pieter-Jan Coenraads ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Gas Chromatography Mass Spectrometry ◽  
Chromatography Mass Spectrometry ◽  
Layer Chromatography
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