A challenge of several concepts of free thyroxin index for assessing thyroid status in patients with altered thyroid-binding protein capacity.

1983 ◽  
Vol 29 (1) ◽  
pp. 56-59 ◽  
Author(s):  
T J Wilke
Keyword(s):  
Normal Values ◽  
Binding Capacity ◽  
Curvilinear Relationship ◽  
Ideal Model ◽  
Thyroid Status ◽  
Specific Uptake ◽  
Altered Thyroid ◽  
Thyroglobulin Concentration ◽  
Ideal Free ◽  
The Ideal

Abstract I compared values for the free thyroxin index derived from data obtained by four triiodothyronine-uptake kits for 93 euthyroid subjects with normal or altered thyroxin-binding globulin binding capacity. In addition, I devised a mathematical model of an "ideal" free thyroxin index. Only one uptake kit satisfactorily normalized values for the free thyroxin index in the increased thyroglobulin groups, as compared with the control. The other three demonstrated contrasting patterns of free thyroxin index variation as compared with normal, when thyroglobulin concentrations were increased. By all four uptake tests, values for the free thyroxin index in thyroglobulin-deficient patients were significantly lower than normal. Values derived from one uptake kit behaved similarly to those of the "ideal" model. The failure of the free thyroxin index to compensate for increases in thyroglobulin concentration is therefore a function of specific uptake methods rather than a characteristic of free thyroxin index per se. However, the free thyroxin index is not a true reflection of thyroid status in patients with thyroglobulin deficiency. The model suggests that a curvilinear relationship between triiodothyronine uptake and the concentration of thyroxin-binding globulin can result in a free thyroxin index that corrects for increases in thyroglobulin binding capacity.

Happiness, Virtue, and Political Society

2018 ◽  
Author(s):  
T. M. Rudavsky
Keyword(s):  
Moral Philosophy ◽  
Political Behavior ◽  
Political Society ◽  
Ideal Model ◽  
The Road ◽  
Doctrine Of The Mean ◽  
The Mean ◽  
The Ideal ◽  
Divine Law

Chapter 9 is concerned with social and political behavior. Even in the context of moral philosophy, Jewish philosophers discuss issues within the wider context of a rational scientific perspective. This chapter begins with specific moral codes developed by Jewish thinkers, focusing in particular upon the works of Ibn Gabirol, Baḥya ibn Paquda, Maimonides, and Crescas. Can there be ethical dictates independent of the commandments? The rabbis already worried whether there existed a domain of “right behavior” that pre-dates, or exists independently of, divine commandment. Does Aristotle’s doctrine of the mean apply to divine law? Furthermore, can all humans achieve intellectual perfection? Is the road the same, and open, to all? And is there only one road to ultimate felicity, or are there many routes? The chapter ends with a discussion of whether human felicity can be achieved in this life, and whether the prophet best represents the ideal model for such achievement.

scholarly journals Using argumentation theory to identify the challenges of shared decision-making when the doctor and the patient have a difference of opinion

2012 ◽  
Vol 1 (2) ◽  
pp. 26 ◽  
Author(s):  
Claudia A. Zanini ◽  
Sara Rubinelli
Keyword(s):  
Decision Making ◽  
Dispute Resolution ◽  
Shared Decision Making ◽  
Communication Skills ◽  
Critical Discussion ◽  
Argumentation Theory ◽  
Shared Decision ◽  
Ideal Model ◽  
Difference Of Opinion ◽  
The Ideal

This paper aims to identify the challenges in the implementation of shared decision-making (SDM) when the doctor and the patient have a difference of opinion. It analyses the preconditions of the resolution of this difference of opinion by using an analytical and normative framework known in the field of argumentation theory as the ideal model of critical discussion. This analysis highlights the communication skills and attitudes that both doctors and patients must apply in a dispute resolution-oriented communication. Questions arise over the methods of empowerment of doctors and patients in these skills and attitudes as the preconditions of SDM. Overall, the paper highlights aspects in which research is needed to design appropriate programmes of training, education and support in order to equip doctors and patients with the means to successfully engage in shared decision-making.

Analytical Solutions of the Ideal Model for Gradient Liquid Chromatography

2006 ◽  
Vol 78 (22) ◽  
pp. 7828-7840 ◽  
Author(s):  
Weiqiang Hao ◽  
Xiangmin Zhang ◽  
Keyong Hou
Keyword(s):  
Liquid Chromatography ◽  
Analytical Solutions ◽  
Ideal Model ◽  
Gradient Liquid Chromatography ◽  
The Ideal

Foraging behaviour in tadpoles of the bronze frogRana temporalis: Experimental evidence for the ideal free distribution

2004 ◽  
Vol 29 (2) ◽  
pp. 201-207 ◽  
Author(s):  
Dheeraj K. Veeranagoudar ◽  
Bhagyashri A. Shanbhag ◽  
Srinivas K. Saidapur
Keyword(s):  
Experimental Evidence ◽  
Foraging Behaviour ◽  
Ideal Free Distribution ◽  
Free Distribution ◽  
Ideal Free ◽  
The Ideal

Aggregation and the `Ideal Free' Distribution

10.2307/4456 ◽  
1983 ◽  
Vol 52 (3) ◽  
pp. 821 ◽  
Author(s):  
William J. Sutherland
Keyword(s):  
Ideal Free Distribution ◽  
Free Distribution ◽  
Ideal Free ◽  
The Ideal

Properties of 5′-deiodinase of 3,3′,5′-triiodothyronine in rat skeletal muscle

1989 ◽  
Vol 120 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Fujiko Tsukahara ◽  
Teruko Nomoto ◽  
Michiko Maeda
Keyword(s):  
Skeletal Muscle ◽  
Drinking Water ◽  
Incubation Medium ◽  
Marked Reduction ◽  
Daily Administration ◽  
Type I ◽  
Rat Skeletal Muscle ◽  
Thyroid Status ◽  
Altered Thyroid

Abstract. To characterize rT3 5′-deiodinase (5′D) in rat skeletal muscle, the effects of altered thyroid status and PTU on rT3 5′D were studied. rT3 5′D activity was measured by incubating homogenates of rat skeletal muscle with [125]rT3, iodine labelled in the outer ring, in the presence of 20 mmol/l DL-dithiothreitol. This activity was observed to increase significantly 24 h after a single sc injection of T3 (75 μg/kg). The increase following the daily administration of this drug (15 or 75 μg/kg) for 3 and 14 days was dependent on the dose and number of previous days of injection. A significant decrease in activity was observed 2 weeks after thyroidectomy. The addition of 0.1 mmol/l 6-n-propyl-2-thiouracil (PTU) to the incubation medium in vitro caused a marked reduction in the activity in homogenates of skeletal muscle from hypothyroid, euthyroid and hyperthyroid rats. PTU, present at 0.05% in the drinking water for 2 weeks virtually abolished it. The properties of rT3 5′D in rat skeletal muscle thus appear to be essentially the same as those of type I enzyme with respect to response toward altered thyroid status and PTU.

CAPACITY OF THYROXINE-BINDING GLOBULIN TO BIND TRIIODOTHYRONINE AND THYROXINE IN MATERNAL AND CORD BLOOD

PEDIATRICS ◽  
1962 ◽  
Vol 29 (3) ◽  
pp. 369-375
Author(s):  
William M. Michener ◽  
W. Newlon Tauxe ◽  
Alvin B. Hayles
Keyword(s):  
Cord Blood ◽  
Normal Values ◽  
Binding Capacity ◽  
Quantitative Difference ◽  
Maternal Blood ◽  
Blood Samples ◽  
Thyroxine Binding Globulin

Normal values for the measurement of thyroidal function using the erythrocytic uptake of I131-labeled triiodothyronine and the thyroxine-binding capacity of the inter-alpha globulin were established. Paired maternal and cord blood samples collected at the time of delivery were studied with these methods. The erythrocytic uptake of labeled hormone was increased in cord blood as compared to maternal blood. Cord blood apparently binds exogenous triiodothyronine in a different manner than it does exogenous thyroxine. Whether this is a qualitative or quantitative difference was not shown in this study.

A VISUAL METAPHOR OF THE MEDIEVAL SOCIETY IN THE LATE 15th - EARLY 16th CENTURIES RUSSIAN “IN THEE REJOICETH” ICONS

2021 ◽  
Vol 29 (1) ◽  
pp. 99-122
Author(s):  
Ludmila Sukina ◽  
Keyword(s):  
Capital City ◽  
Visual Metaphor ◽  
Ideal Model ◽  
Human Race ◽  
City Community ◽  
Russian State ◽  
Spiritual Authority ◽  
The City ◽  
The Ideal

The author examines the “In Thee rejoiceth” icons as visual sources that make it possible to reconstruct the ideal model of medieval society in the Moscow culture of the late 15th and early 16th centuries. This icon type, which includes the scenes of “Human race” collective praying to the Mother of God, is of Russian origin. Unlike other works of that time typologically close to it (“The Intercession”, “The Congregation of Our Lady”, “The Congregation of All Saints”, etc.), the “In Thee rejoiceth” icons demonstrate a historical connection to religious and socio-cultural facts of the Muscovy state. They clearly express the idea of Muscovy enjoying special patronage of the Mother of God, whose cult was actively developed in Moscow, the city that, as was believed at the Grand Dukes’ court, inherited the traditions and the spiritual authority of Constantinople. The depiction of the “Human race” in the “In Thee rejoiceth” icons can be viewed as a metaphorical image of the capital city community consisting of different groups of clergy and laity. This image corresponded to the ideas of the authorities and the population of the Russian state that existed under Ivan III and Vasili III.

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