scholarly journals Bioactive Constituents of Brazilian Red Propolis

2006 ◽  
Vol 3 (2) ◽  
pp. 249-254 ◽  
Author(s):  
Boryana Trusheva ◽  
Milena Popova ◽  
Vassya Bankova ◽  
Svetlana Simova ◽  
Maria Cristina Marcucci ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Natural Source ◽  
Scavenging Activity ◽  
Bioactive Constituents ◽  
Brazilian Propolis ◽  
First Time

In a new propolis type, red Brazilian propolis, 14 compounds were identified (six of them new for propolis), among them simple phenolics, triterepenoids, isoflavonoids, prenylated benzophenones and a naphthoquinone epoxide (isolated for the first time from a natural source). Three of the major components demonstrated significant antimicrobial activity, and two (obtained as inseparable mixture) possessed radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH).

Potent Free Radical Scavenging Activity of Propol Isolated from Brazilian Propolis

1997 ◽  
Vol 52 (11-12) ◽  
pp. 828-833 ◽  
Author(s):  
Purusotam Basnet ◽  
Tetsuya Matsuno ◽  
Richard Neidlein
Keyword(s):  
Free Radical ◽  
Vitamin E ◽  
Superoxide Anion ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Water Extract ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity ◽  
Brazilian Propolis

Abstract We evaluated free radical scavenging activity of the water, methanol and chloroform ex­tracts of propolis in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and xanthine-xanthine oxidase (XOD) generated superoxide anion assay systems. The free radical scavenging activity guided fractionation and chemical analysis led to the isolation of a new compound, propol {3-[4-hydroxy-3-(3-oxo-but-1-enyl)-phenyl]-acrylic acid) from the water extract, which was more potent than most common antioxidants such as vitamin C and vitamin E (α-tocopherol) in these assay systems.

Radical scavenging activity ofCrocus sativus L. extract and its bioactive constituents

2005 ◽  
Vol 19 (11) ◽  
pp. 997-1000 ◽  
Author(s):  
A. N. Assimopoulou ◽  
Z. Sinakos ◽  
V. P. Papageorgiou
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity ◽  
Bioactive Constituents

scholarly journals Tetrapleura tetraptera of Ghanaian Origin: Phytochemistry, Antioxidant and Antimicrobial Activity of Extracts of Plant Parts

2020 ◽  
pp. 78-96
Author(s):  
Christopher Larbie ◽  
Felix Charles Mills- Robertson ◽  
Emmanuel Bright Quaicoe ◽  
Rita Opoku ◽  
Naomi Chounbayor Kabiri ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Biological Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Stem Bark ◽  
Scavenging Activity ◽  
Methanolic Extracts ◽  
Healthcare Needs ◽  
Tetrapleura Tetraptera ◽  
Phytochemical Constituents

Introduction: The role of medicinal plants in meeting the healthcare needs of the populace, particularly in developing countries cannot be overemphasized. They provide holistic treatment and wellbeing due to a plethora of phytochemicals found in them. Among such is Tetrapleura tetraptera (Schum. & Thonn.) Taub., a multipurpose tree plant with varied biological activities. The current study was aimed at assessing the basic phytochemical constituents, free radical scavenging activity as well as the antimicrobial effect on various solvent extracts of leaves, fruit and stem bark of T. tetraptera of Ghanaian origin. Materials and Methods: Aqueous, 50% hydroethanolic and methanolic extracts were made from the leaves, fruits, and stem bark of T. tetraptera. They were assessed for the qualitative and quantitative phytochemical constituents, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, antimicrobial activity as well as the spectroscopic properties (Ultraviolet – visible and Fourier-transform infrared spectroscopy). Compounds in the methanolic extracts were evaluated using the gas chromatography–mass spectrometry. Results: Tannins, reducing sugars, coumarins and flavonoids were present in all extracts while hydroethanolic and methanolic extracts were rich in phenols, tannins and flavonoids, especially for the stem bark. Leaf extracts had better antimicrobial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans and Proteus mirabilis. Conclusion: Generally, leaves and stem bark extracts of T. tetraptera are rich in biologically active phytochemicals, supporting their use in ethnomedicine and could be exploited further for other biological activities.

A New Chlorine-containing Glucosyl-fused Compound from Curculigo glabrescens

2009 ◽  
Vol 64 (9) ◽  
pp. 1077-1080 ◽  
Author(s):  
Cui-Cui Zhu ◽  
Tian-Ming Wang ◽  
Kai-Jin Wang ◽  
Ning Li
Keyword(s):  
Spectroscopic Analysis ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
2D Nmr ◽  
Free Radical Scavenging ◽  
Scavenging Activity ◽  
Dpph Assay ◽  
Etoh Extract ◽  
Structure Activity ◽  
First Time

A new chlorine-containing glucosyl-fused compound, crassifoside H (1), was isolated from the EtOH extract of the rhizomes of Curculigo glabrescens. The structure was established on the basis of MS, IR, 1D and 2D NMR experiments. In addition, seven known compounds (2 - 8) were isolated and identified by spectroscopic analysis and comparison of their spectral data with those reported previously. All the compounds were isolated from this plant for the first time. The free radical scavenging activity of the isolated compounds was evaluated by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Compounds 1 and 2 showed strong radical scavenging activities. The primary structure-activity relationship is also discussed.

Evaluation of radical scavenging activity, intestinal cell viability and antifungal activity of Brazilian propolis by-product

2018 ◽  
Vol 105 ◽  
pp. 537-547 ◽  
Author(s):  
Lizziane de Francisco ◽  
Diana Pinto ◽  
Hélen Rosseto ◽  
Lucas Toledo ◽  
Rafaela Santos ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Cell Viability ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Intestinal Cell ◽  
Scavenging Activity ◽  
Brazilian Propolis

scholarly journals Volatile Components of Selected Liverworts, and Cytotoxic, Radical Scavenging and Antimicrobial Activities of Their Crude Extracts

2010 ◽  
Vol 5 (9) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Ismiarni Komala ◽  
Takuya Ito ◽  
Yasuyuki Yagi ◽  
Fumihiro Nagashima ◽  
Yoshinori Asakawa
Keyword(s):  
Mass Spectrometry ◽  
Antimicrobial Activity ◽  
Aromatic Compounds ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Antimicrobial Activities ◽  
Gas Chromatography Mass Spectrometry ◽  
Volatile Components ◽  
Scavenging Activity ◽  
Crude Extracts

Crude extracts of the Tahitian liverworts Mastigophora Diclados and Frullania sp., the Indonesian Frullania sp., Dumortiera hirsuta and Marchantia sp., and the Japanese Porella perrottetiana were investigated chemically by using gas chromatography-mass spectrometry (GC-MS). All extracts contained various volatile sesqui- and diterpenoids and a few aromatic compounds. The Tahitian M. diclados and Frullania sp., and the Indonesian Frullania sp. exhibited cytotoxic activity against HL-60 and KB cell lines. The extracts of the Tahitian M. diclados and the Indonesian Marchantia sp. showed radical scavenging activity, whereas the crude extracts of the Tahitian M. diclados and Frullania sp., and the Indonesian Frullania and Marchantia sp. showed antimicrobial activity against Staphylococcus aureus and Bacillus subtilis.

scholarly journals Correction: Development of a microparticulate system containing Brazilian propolis by-product and gelatine for ascorbic acid delivery: evaluation of intestinal cell viability and radical scavenging activity

2018 ◽  
Vol 9 (8) ◽  
pp. 4518-4518
Author(s):  
Lizziane Maria Belloto de Francisco ◽  
Diana Pinto ◽  
Hélen Cássia Rosseto ◽  
Lucas de Alcântara Sica de Toledo ◽  
Rafaela Said dos Santos ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Cell Viability ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Intestinal Cell ◽  
Scavenging Activity ◽  
Brazilian Propolis

Correction for ‘Development of a microparticulate system containing Brazilian propolis by-product and gelatine for ascorbic acid delivery: evaluation of intestinal cell viability and radical scavenging activity’ by Lizziane Maria Belloto de Francisco et al., Food Funct., 2018, DOI: 10.1039/c8fo00863a.

scholarly journals Di- and Triterpenoids Isolation and LC-MS Analysis of Salvia marashica Extracts with Bioactivity Studies

2021 ◽  
Vol 15 (6) ◽  
pp. 463-475
Author(s):  
Sibel Kıran Aydın ◽  
Abdulselam Ertaş ◽  
Mehmet Boğa ◽  
Ebru Erol ◽  
Gülbahar Özge Alim Toraman ◽  
...  
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Cation Radical ◽  
Total Phenolic ◽  
Scavenging Activity ◽  
Methanol Extracts ◽  
Aerial Parts ◽  
Ms Analysis ◽  
Abietane Diterpenes ◽  
First Time

In this study, dichloromethane, acetone, and methanol extracts of the aerial parts of the Salvia marashica plant which is an endemic species to Anatolia, were investigated. The total phenolic amounts of these extracts were determined as pyrocatechol equivalent and total flavonoids as quercetin equivalent. Antioxidant activity was determined by four complementary methods including inhibition of lipid peroxidation (by β-carotene color expression), DPPH free radical scavenging activity, ABTS cation radical scavenging activity and CUPRAC methods. Anticholinesterase activity of the extracts was investigated by the Ellman method against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. Viability and cytotoxic activity tests were carried out on the fibroblast L929 cells and cytotoxic A549 lung cancer cells, respectively. The triterpenoids and diterpenoids constitute the major secondary metabolites of the S. marashica acetone and methanol extracts isolated by chromatographic methods. Their structures were determined based on spectroscopic methods, namely NMR and mass analyses. Ten terpenoids were obtained from either acetone or methanol extracts of the S. marashica. Seven of them were triterpenoids, elucidated as lupeol, lupeol-3-acetate, lup-12, 20(29)-diene, lup-20(29)-ene, α-amyrin-tetracosanoate, oleanolic acid and ursolic acid besides a steroid β-sitosterol. Two abietane diterpenes, abieta-8,11,13-triene (1) and 18-acetoxymethylene-abieta-8,11,13-triene (2), were obtained from the acetone extract which were isolated from a Salvia species for the first time in the present study. The methanol extract was found to be very rich in rosmarinic acid determined by LC-MS/MS analysis.

scholarly journals SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF INDOLE DERIVATIVES BEARING BENZIMIDAZOLE/BENZOTHIAZOLE MOIETY

2017 ◽  
Vol 9 (8) ◽  
pp. 128 ◽  
Author(s):  
Basavaraj Shivabasappa Naraboli ◽  
Jayaprakash Sharanappa Biradar
Keyword(s):  
Antimicrobial Activity ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Biological Evaluation ◽  
Diffusion Method ◽  
Scavenging Activity ◽  
Indole Derivatives ◽  
Indole Ring ◽  
Ferric Ions ◽  
Antioxidant Power

Objective: The present work deals with the synthesis and characterization of biologically active new indole derivatives viz., 2-((1H-benzo[d]imidazol-2-yl)thio)-N-(4-(3-(1H-indol-3-yl)acryloyl)phenyl)acetamide 6a-d, N-(4-(3-(1H-indol-3-yl)acryloyl)phenyl)-2-((5-methoxy-1H-benzo[d]imidazol-2-yl)thio)acetamide 7a-d and N-(4-(3-(1H-indol-3-yl)acryloyl)phenyl)-2-(benzo[d]thiazol-2-ylthio)acetamide 8a-d.Methods: All these newly synthesized compounds were screened for their in vitro antimicrobial activity by an agar plate diffusion method, antioxidant activities: like 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging activity (RSA), ferric ions (Fe3+) reducing antioxidant power (FRAP), ferrous (Fe2+) metal ion chelating activity.Results: The structures of all the newly synthesized compounds were characterized by their IR, 1HNMR, mass spectral studies and elemental analysis. Compounds 6b, 7a, 7b, 8a and 8b exhibited good radical scavenging activity (RSA) at a concentration 100 µg/ml, compounds 7b, 7c, 7d and 8b displayed good ferric ions (Fe3+) reducing antioxidant power (FRAP) at a concentration 100 µg/ml, compounds 7b, 7d, 8b and 8d showed good ferrous (Fe2+) ion metal chelating activity. Compounds 7d and 8d exhibited good activity against all the screened bacteria and fungi.Conclusion: The synthesised compounds 7d having methoxy group at 5 positions of benzimidazoles ring, bromo group at 5 positions of indole ring, and 8d having bromo group at position 5 of indole ring, both the compounds have exhibited potent antimicrobial activity. Some compounds have shown very good antioxidant activity.

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