Molecular evolution of the Escherichia coli chromosome. II. Clonal segments.
Keyword(s):
A Cell
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Abstract Remarkable sequence similarities in the trp region among Escherichia coli strains of diverse natural origins imply the existence of worldwide clones of very recent origin. This in turn implies a low rate of fixation of new universally favorable alleles, which carry adjacent stretches of chromosome to high frequency. These clonal segments begin as entire chromosomes; recombination shortens them progressively by substituting less closely related homologous DNA. The rate of this recombination, comprising the introduction of a homologous chromosomal fragment to a cell and the replacement of part of the original chromosome, is estimated from observations.
1964 ◽
Vol 29
(3)
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pp. 814-824
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1949 ◽
Vol 181
(1)
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pp. 171-182
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1996 ◽
Vol 116
(1)
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pp. 1-7
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Keyword(s):
1988 ◽
Vol 8
(8)
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pp. 3439-3447
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Keyword(s):
2005 ◽
Vol 68
(6)
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pp. 1176-1187
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2017 ◽
Vol 45
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pp. 92-103
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