scholarly journals SSDoH in Latinxs: Factors of Influence

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 81-81
Author(s):  
David Marquez
Keyword(s):  
Diabetes Mellitus ◽  
Formal Education ◽  
The United States ◽  
Syndrome Type ◽  
Structural Determinants ◽  
Resilience Factors ◽  
Factors Of Influence ◽  
Low Levels

Abstract Research with Latinxs/os/as regarding Alzheimer’s disease and related dementias (ADRD) is lacking. This is staggering because among Latinxs in the United States, the number diagnosed with ADRD is expected to grow by more than 800% from 2012 to 2060 (Wu et al., 2016). Older Latinxs have a high risk and prevalence of ADRD - partially attributed to their longer life spans and the presence of adverse risk factors such as metabolic syndrome, type 2 diabetes mellitus, and other cardiovascular conditions (Chin et al., 2011). What is often missing in the discussion is the role of social and structural determinants of health (SSDOH) in this population. Overall Latinxs have low levels of formal education, work in physically demanding jobs, and experience immigration stress. How these and other SSDoH influence Latinxs will be discussed; as well as potential resilience factors like familial relationships, and religiosity or spirituality.

Acatalasemia and type 2 diabetes mellitus

2015 ◽  
Vol 156 (10) ◽  
pp. 393-398 ◽  
Author(s):  
László Góth ◽  
Teréz Nagy ◽  
Miklós Káplár
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Hydrogen Peroxide ◽  
Type 2 Diabetes Mellitus ◽  
Deoxyribonucleic Acid ◽  
Low Levels ◽  
Toxic Concentrations ◽  
Water Hydrogen

The catalase enzyme decomposes the toxic concentrations of hydrogen peroxide into oxygen and water. Hydrogen peroxide is a highly reactive small molecule and its excessive concentration may cause significant damages to proteins, deoxyribonucleic acid, ribonucleic acid and lipids. Acatalasemia refers to inherited deficiency of the catalase enzyme. In this review the authors discuss the possible role of the human catalase enzyme, the metabolism of hydrogen peroxide, and the phenomenon of hydrogen peroxide paradox. In addition, they review data obtained from Hungarian acatalasemic patients indicating an increased frequency of type 2 diabetes mellitus, especially in female patients, and an early onset of type 2 diabetes in these patients. There are 10 catalase gene variants which appear to be responsible for decreased blood catalase activity in acatalasemic patients with type 2 diabetes. It is assumed that low levels of blood catalase may cause an increased concentration of hydrogen peroxide which may contribute to the pathogenesis of type 2 diabetes mellitus. Orv. Hetil., 2015, 156(10), 393–398.

Role of Vitamin C in Endothelial Dysfunction in Patients with Type 2 Diabetes Mellitus Introduction

2020 ◽  
Vol 11 (2) ◽  
pp. 1701
Author(s):  
Nermien Abd El Rahman Ibraheim ◽  
Fatema El Zahraa Sayed Bukhary ◽  
Yehia Zakareia Mahmoud ◽  
Mahmoud Ragab Mohamed ◽  
Salama Rabei Abdel-Rahim
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Endothelial Dysfunction ◽  
Vitamin C

The GSTM1 and GSTT1 Null Genotypes Increase the Risk for Type 2 Diabetes Mellitus and the Subsequent Development of Diabetic Complications: A Meta-analysis

2018 ◽  
Vol 15 (1) ◽  
pp. 31-43 ◽  
Author(s):  
Sayantan Nath ◽  
Sambuddha Das ◽  
Aditi Bhowmik ◽  
Sankar Kumar Ghosh ◽  
Yashmin Choudhury
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Meta Analysis ◽  
Subsequent Development ◽  
Asian Population ◽  
Gstm1 Null Genotype ◽  
Increased Risk

Background:Studies pertaining to association of GSTM1 and GSTT1 null genotypes with risk of T2DM and its complications were often inconclusive, thus spurring the present study.Methods:Meta-analysis of 25 studies for evaluating the role of GSTM1/GSTT1 null polymorphisms in determining the risk for T2DM and 17 studies for evaluating the role of GSTM1/GSTT1 null polymorphisms in development of T2DM related complications were conducted.Results:Our study revealed an association between GSTM1 and GSTT1 null polymorphism with T2DM (GSTM1; OR=1.37;95% CI =1.10-1.70 and GSTT1; OR=1.29;95% CI =1.04-1.61) with an amplified risk of 2.02 fold for combined GSTM1-GSTT1 null genotypes. Furthermore, the GSTT1 null (OR=1.56;95%CI=1.38-1.77) and combined GSTM1-GSTT1 null genotypes (OR=1.91;95%CI=1.25- 2.94) increased the risk for development of T2DM related complications, but not the GSTM1 null genotype. Stratified analyses based on ethnicity revealed GSTM1 and GSTT1 null genotypes increase the risk for T2DM in both Caucasians and Asians, with Asians showing much higher risk of T2DM complications than Caucasians for the same. </P><P> Discussion: GSTM1, GSTT1 and combined GSTM1-GSTT1 null polymorphism may be associated with increased risk for T2DM; while GSTT1 and combined GSTM1-GSTT1 null polymorphism may increase the risk of subsequent development of T2DM complications with Asian population carrying an amplified risk for the polymorphism.Conclusion:Thus GSTM1 and GSTT1 null genotypes increases the risk for Type 2 diabetes mellitus alone, in combination or with regards to ethnicity.

Role of Yoga in Lifestyle Disorders w.s.r. to Diabetes Mellitus Type-2

2019 ◽  
Vol 4 (03) ◽  
Author(s):  
Tushar K. Pardeshi ◽  
Sachinkumar Patil
Keyword(s):  
Diabetes Mellitus ◽  
Diabetes Mellitus Type 2 ◽  
Healthy Lifestyle ◽  
Working Hours ◽  
Behavioral Pattern ◽  
Current Trends ◽  
Diet Pattern ◽  
Speed And Accuracy

21st century is full of stress requiring more speed and accuracy. In today’s world of competition, diet pattern, lifestyle and behavioral pattern of people has changed. Late working hours, deadlines of work and stress have become a parcel of daily life. Due to this people have won’t have time for exercise and Yoga and end up in various lifestyle disorder, like Diabetes mellitus, Dyslipidemia, Obesity, Cardiovascular diseases etc. Diabetes mellitus is one of most leading disorder in all of them. The worldwide prevalence of D.M. has raised dramatically over past two decades, from an estimated 30 million cases in 1985 to 177 million in 2000. Based on current trends, > 360 million individuals will have diabetes by the year 2030. Diabetes mellitus is mentioned in our Samhitas as disorder of lethargic and exercise less lifestyle disorder and termed it as Madhumeha. Caused by mainly Apathyaahara and Viharsevana. Chikitsa of Madhumeha focused on Pathyaaahara and Vihar (lifestyle) in management of Madhumeha. This article is deal with healthy lifestyle including Yoga mentioned in Ayurveda Samhita for management of prevention and treatment of Lifestyle disorders.

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