scholarly journals Complete nucleotide sequence of the multidrug resistance IncA/C plasmid pR55 from Klebsiella pneumoniae isolated in 1969

2012 ◽  
Vol 67 (10) ◽  
pp. 2354-2360 ◽  
Author(s):  
B. Doublet ◽  
D. Boyd ◽  
G. Douard ◽  
K. Praud ◽  
A. Cloeckaert ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Nucleotide Sequence ◽  
Klebsiella Pneumoniae ◽  
Complete Nucleotide Sequence

scholarly journals Complete Nucleotide Sequence of the IncN Plasmid Encoding IMP-6 and CTX-M-2 from Emerging Carbapenem-Resistant Enterobacteriaceae in Japan

2014 ◽  
Vol 59 (2) ◽  
pp. 1356-1359 ◽  
Author(s):  
Shizuo Kayama ◽  
Norifumi Shigemoto ◽  
Ryuichi Kuwahara ◽  
Kenshiro Oshima ◽  
Hideki Hirakawa ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Nucleotide Sequence ◽  
Klebsiella Pneumoniae ◽  
Dna Sequence ◽  
Complete Nucleotide Sequence ◽  
Carbapenem Resistance ◽  
Content Type ◽  
Carbapenem Resistant ◽  
The Family ◽  
Carbapenem Resistant Enterobacteriaceae

ABSTRACTWe have determined the DNA sequence ofKlebsiella pneumoniaemultidrug resistance plasmid pKPI-6, which is a self-transmissible IncN-type plasmid. pKPI-6 harboringblaIMP-6andblaCTX-M-2confers a stealth-type carbapenem resistance phenotype on members of the familyEnterobacteriaceaethat is not detectable with imipenem. pKPI-6 is already epidemic in Japan, favoring the dissemination of IMP-6 and CTX-M-2 in members of the familyEnterobacteriaceae.

scholarly journals Complete Nucleotide Sequence of a Novel Plasmid Bearing the High-Level Tigecycline Resistance Gene tet(X4)

2019 ◽  
Vol 63 (11) ◽  
Author(s):  
Liang-Xing Fang ◽  
Chong Chen ◽  
Dong-Ling Yu ◽  
Ruan-Yang Sun ◽  
Chao-Yue Cui ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Multidrug Resistance ◽  
Sequence Analysis ◽  
Nucleotide Sequence ◽  
Complete Nucleotide Sequence ◽  
Hybrid Plasmid ◽  
Content Type ◽  
Clinically Significant ◽  
High Level ◽  
Plasmid Backbone

ABSTRACT We reported the complete nucleotide sequence of a tet(X4)-carrying plasmid, pSTB20-1T, from a tigecycline-resistant Escherichia coli isolate in China. Sequence analysis indicated that pSTB20-1T contains a hybrid plasmid backbone and a tet(X4)-containing multidrug resistance region, likely originated through recombination of multiple plasmids. tet(X4) was flanked by two ISCR2, which may be responsible for tet(X4) mobilization. The occurrence and transmission of this novel hybrid plasmid may exacerbate the spread of the clinically significant tet(X4) gene.

scholarly journals Complete Nucleotide Sequence of Two Multidrug-Resistant IncR Plasmids from Klebsiella pneumoniae

2014 ◽  
Vol 58 (7) ◽  
pp. 4207-4210 ◽  
Author(s):  
Fabrice Compain ◽  
Lionel Frangeul ◽  
Laurence Drieux ◽  
Charlotte Verdet ◽  
Sylvain Brisse ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Multidrug Resistance ◽  
Nucleotide Sequence ◽  
Resistance Genes ◽  
Complete Nucleotide Sequence ◽  
Clinical Importance ◽  
Antibiotic Resistance Genes ◽  
Multidrug Resistant ◽  
Resistance Determinants ◽  
Gene Carriers

ABSTRACTWe report here the complete nucleotide sequence of two IncR replicons encoding multidrug resistance determinants, including β-lactam (blaDHA-1,blaSHV-12), aminoglycoside (aphA1,strA,strB), and fluoroquinolone (qnrB4,aac6′-1b-cr) resistance genes. The plasmids have backbones that are similar to each other, including the replication and stability systems, and contain a wide variety of transposable elements carrying known antibiotic resistance genes. This study confirms the increasing clinical importance of IncR replicons as resistance gene carriers.

scholarly journals Complete Nucleotide Sequence of KPC-3-Encoding Plasmid pKpQIL in the Epidemic Klebsiella pneumoniae Sequence Type 258

2010 ◽  
Vol 54 (10) ◽  
pp. 4493-4496 ◽  
Author(s):  
Azita Leavitt ◽  
Inna Chmelnitsky ◽  
Yehuda Carmeli ◽  
Shiri Navon-Venezia
Keyword(s):  
Nucleotide Sequence ◽  
Klebsiella Pneumoniae ◽  
Dna Sequence ◽  
Complete Nucleotide Sequence ◽  
Sequence Type ◽  
Incompatibility Group ◽  
Carbapenem Resistant ◽  
Transmissible Plasmid ◽  
Clone Sequence

ABSTRACT We have determined the entire DNA sequence of plasmid pKpQIL, the bla KPC-3-carrying plasmid harbored by the carbapenem-resistant Klebsiella pneumoniae clone sequence type 258 (ST 258) in Israel. pKpQIL is a 113,637-bp, self-transmissible plasmid that belongs to the incompatibility group IncFII. It consists of a large backbone of a pKPN4-like plasmid and carries the bla KPC-3-containing Tn4401a transposon of a pNYC-like plasmid.

scholarly journals Complete Nucleotide Sequence of pCTX-M360, an Intermediate Plasmid between pEL60 and pCTX-M3, from a Multidrug-Resistant Klebsiella pneumoniae Strain Isolated in China

2009 ◽  
Vol 53 (12) ◽  
pp. 5291-5293 ◽  
Author(s):  
Wen-han Zhu ◽  
Lan Luo ◽  
Jia-yi Wang ◽  
Xiao-hong Zhuang ◽  
Ling Zhong ◽  
...  
Keyword(s):  
Sequence Analysis ◽  
Nucleotide Sequence ◽  
Klebsiella Pneumoniae ◽  
Complete Nucleotide Sequence ◽  
Multidrug Resistant ◽  
Incompatibility Group ◽  
Extended Spectrum

ABSTRACT In this work we report the characterization of plasmid pCTX-M360, isolated from a Klebsiella pneumoniae strain from China and encoding the CTX-M-3 extended-spectrum β-lactamase. Sequence analysis of pCTX-M360 revealed extensive similarity with pEL60 and pCTX-M3, two other enterobacterial plasmids of the IncL/M incompatibility group. Compared to pEL60, pCTX-M360 contains several insertions but lacks most of a 27-kb insert found in pCTX-M3, suggesting that it could be an evolutionary intermediate between pEL60 and pCTX-M3.

scholarly journals Complete Nucleotide Sequence of an Escherichia coli Sequence Type 410 Strain Carrying bla NDM-5 on an IncF Multidrug Resistance Plasmid and bla OXA-181 on an IncX3 Plasmid

2018 ◽  
Vol 6 (5) ◽  
Author(s):  
Søren Overballe-Petersen ◽  
Louise Roer ◽  
Kim Ng ◽  
Frank Hansen ◽  
Ulrik S. Justesen ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Multidrug Resistance ◽  
Nucleotide Sequence ◽  
Resistance Genes ◽  
Complete Nucleotide Sequence ◽  
Sequence Type ◽  
Nanopore Sequencing ◽  
Incompatibility Group ◽  
E Coli ◽  
Resistance Plasmid

ABSTRACT Using Nanopore sequencing, we describe here the circular genome of an Escherichia coli sequence type 410 (ST410) strain with five closed plasmids. A large 111-kb incompatibility group F (IncF) plasmid harbored bla NDM-5 and 16 other resistance genes. A 51-kb IncX3 plasmid carried QnrS1 and bla OXA-181 . E. coli isolates with both bla NDM-5 and bla OXA-181 carbapenemases are rare.

scholarly journals Complete Sequence of ablaKPC-Harboring Cointegrate Plasmid Isolated from Escherichia coli

2015 ◽  
Vol 59 (5) ◽  
pp. 2956-2959 ◽  
Author(s):  
Kalyan D. Chavda ◽  
Liang Chen ◽  
Michael R. Jacobs ◽  
Albert D. Rojtman ◽  
Robert A. Bonomo ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Nucleotide Sequence ◽  
Klebsiella Pneumoniae ◽  
Horizontal Transfer ◽  
Complete Nucleotide Sequence ◽  
Complete Sequence ◽  
Plasmid Transfer ◽  
Content Type

ABSTRACTHorizontal transfer ofblaKPC-harboring plasmids contributes significantly to the inter- and intraspecies spread ofKlebsiella pneumoniaecarbapenemase (KPC). Here we report the complete nucleotide sequence of ablaKPC-harboring IncFIA plasmid, pBK32533, fromEscherichia coli. pBK32533 is a cointegrate plasmid comprising of a 72-kb sequence identical to that of the nonconjugative pBK30661 plasmid plus an additional 170-kb element that harbors the genes for plasmid transfer. pBK32533 demonstrates howblaKPCcan be spread from a nonconjugative plasmid through cointegration.

scholarly journals Complete Nucleotide Sequence of the First KPC-2- and SHV-12-Encoding IncX Plasmid, pKpS90, from Klebsiella pneumoniae

2012 ◽  
Vol 57 (1) ◽  
pp. 618-620 ◽  
Author(s):  
Najiby Kassis-Chikhani ◽  
Lionel Frangeul ◽  
Laurence Drieux ◽  
Christian Sengelin ◽  
Vincent Jarlier ◽  
...  
Keyword(s):  
Nucleotide Sequence ◽  
Klebsiella Pneumoniae ◽  
Complete Nucleotide Sequence ◽  
Sequence Type ◽  
University Hospital ◽  
Incompatibility Group ◽  
Content Type

ABSTRACTWe report the complete nucleotide sequence of the pKpS90 plasmid, carrying theblaKPC-2andblaSHV-12genes. This plasmid was isolated from a sequence type 258 (ST258)Klebsiella pneumoniaestrain responsible for an outbreak in a French university hospital in 2009. pKpS90 is a 53,286-bp plasmid that belongs to the IncX incompatibility group. pKpS90 consists of a backbone from IncX plasmids, in which the KPC-2-encoding Tn4401transposon and ablaSHV-12-encoding region have been inserted.

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