Improving performance of finishing pigs with added valine, isoleucine, and tryptophan: validating a meta-analysis model

Abstract Based on results of a recent meta-analysis, we hypothesized that increased dietary Val, Ile, or Trp could correct possible amino acid interactions because of excess Leu in diets containing high levels of corn protein, namely dried distiller’s grains with solubles (DDGS). A total of 1,200 pigs (PIC TR4 × (Fast LW × PIC L02); initially 33.6 ± 0.6 kg) were used in a 103-d study. The 6 dietary treatments were corn–soybean meal (SBM)-DDGS-based as follows: (1) high SBM and low level of l-Lys HCl (HSBM), (2) high l-Lys HCl and moderate Ile, Val, Trp (AA above NRC 2012 estimates; NC), (3) moderate l-Lys HCl and high Ile, Val, and Trp (PC), and PC with either increased (4) L-Val (PC+Val), (5) L-Ile (PC+Ile), or (6) L-Trp (PC+Trp). Pigs fed the NC diet were predicted to have the poorest average daily gain (ADG), the PC diet to be intermediate, and pigs fed the HSBM, PC+Val, PC+Ile, and PC+Trp have the same and highest predicted ADG. In the grower period (34 to 90 kg), ADG was greater (Ρ < 0.05) for the pigs fed HSBM and PC+Val diets than the NC with pigs fed other diets intermediate. Pigs fed HSBM were more (Ρ < 0.05) efficient (G:F) than the NC and PC with pigs fed other diets intermediate. In the finisher period (90 to 136 kg), ADG was greater (Ρ < 0.05) for pigs fed PC+Ile than that of the NC with pigs fed other diets intermediate. Pigs fed PC+Val had greater (Ρ < 0.05) average daily feed intake (ADFI) than the NC with pigs fed other diets intermediate. However, PC+Ile pigs were more (Ρ < 0.05) efficient than PC+Val with pigs fed other diets intermediate. Overall, ADG was greater (Ρ < 0.05) for pigs fed HSBM, PC+Val, and PC+Ile diets than the NC with pigs fed other diets intermediate. Pigs fed the PC+Val diet had greater (Ρ < 0.05) ADFI than the NC with pigs fed other diets intermediate. No differences were detected between treatments for overall G:F or other carcass characteristics. In conclusion, increasing Val or Ile in high l-Lys-HCl-DDGS-based diets improved growth performance compared with pigs fed diets containing high levels of l-Lys HCl without added Val and Ile. These results present evidence that the recently developed meta-analysis can predict the relative differences in overall ADG for pigs fed the NC, PC, PC+Val, and PC+Ile diets; however, the predicted G:F was less accurate. The data demonstrate that the negative effects of high Leu concentrations in corn-DDGS-based diets can be reversed by increasing the ratios of Val and Ile relative to Lys.

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172 Effects of Dietary Valine, Isoleucine, and Tryptophan Supplementations to Diets Containing Excess Leucine from Corn Protein on Growth Performance of Growing Pigs

Journal of Animal Science ◽

10.1093/jas/skab054.103 ◽

2021 ◽

Vol 99 (Supplement_1) ◽

pp. 61-62

Author(s):

Woongbi Bi Kwon ◽

Jose A Soto ◽

Hans H Stein

Keyword(s):

Block Design ◽

Control Diet ◽

Average Daily Gain ◽

Growing Pigs ◽

Experimental Unit ◽

Negative Effects ◽

Final Body Weight ◽

Corn Protein ◽

Dietary Treatments ◽

Daily Gain

Abstract An experiment was conducted to test the hypothesis that addition of Val, Ile, or Trp alone or in combination will reduce the negative effects of excess Leu in diets for growing pigs. A total of 288 growing pigs (28.6 ± 2.5 kg) were randomly assigned to 1 of 9 dietary treatments in a randomized complete block design. There were 2 barrows and 2 gilts in each pen and 8 replicate pens per treatment. A control diet based on corn and soybean meal and 8 diets based on corn and a high-protein corn product (48% crude protein) with 2 levels of crystalline L-Val (0 or 0.10%), L-Ile (0 or 0.10%), and L-Trp (0 or 0.05%) were formulated. The crystalline L-Val, L-Ile, and L-Trp increased standardized ileal digestible (SID) Val:Lys from 70 to 80%, SID Ile:Lys from 53 to 63%, and SID Trp:Lys from 18 to 23%, respectively. All diets were formulated to contain 1.00% SID Lys and the 8 diets containing corn protein contained 171% SID Leu:Lys. Individual pig weights were recorded at the beginning and at the conclusion of the 28-d experiment. Data were analyzed using the PROC MIXED of SAS with a pen as the experimental unit. Diet was the fixed effect and block and replicate within block were random effects. Results indicated that final body weight and average daily gain were not different between pigs fed the control diet and pigs fed the diet with Val and Trp addition, but greater (P < 0.001) than for pigs fed the diet with Val addition, Ile addition, Trp addition, Val and Ile addition, Ile and Trp addition, or Val, Ile, and Trp addition (Table 1). In conclusion, addition of Val and Trp to diets with excess Leu may prevent negative effects of excess Leu in diets for growing pigs.

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207 Improving Performance of Finishing Pigs with Added Val, Ile, and Trp: Validating a Meta-analysis Model

Journal of Animal Science ◽

10.1093/jas/skaa054.126 ◽

2020 ◽

Vol 98 (Supplement_3) ◽

pp. 70-71

Author(s):

Hayden R Kerkaert ◽

Henrique S Cemin ◽

Mike D Tokach ◽

Jason C Woodworth ◽

Joel M DeRouchey ◽

...

Keyword(s):

Meta Analysis ◽

Block Design ◽

Experimental Unit ◽

Analysis Model ◽

Negative Effects ◽

Distillers Grains With Solubles ◽

Dried Distillers Grains ◽

Corn Protein ◽

Unit Body Weight ◽

Dietary Treatments

Abstract Based on a recent meta-analysis, we hypothesized that increased dietary Val, Ile, or Trp could correct possible amino acid interactions caused by high dietary Leu in diets containing high levels of corn protein, namely dried distillers grains with solubles (DDGS). A total of 1,200 pigs (PIC TR4×(Fast LW×PIC L02); initially 33.6±0.63 kg) were used in a 103-d study. The 6 dietary treatments were corn-soybean meal-DDGS-based diets as follow: low level of Lys-HCl (SBM), high Lys-HCl and moderate Ile, Val, Trp (NC; AA above NRC 2012 estimates), moderate Lys-HCl and high Ile, Val, Trp (PC), and PC with either increased L-Val (Val), L-Ile (Ile), or L-Trp (Trp). Diets contained 30% DDGS until pigs reached approximately 100 kg and then 20% DDGS until market. Data were analyzed as a randomized complete block design using lmer function in lme4 package in R with pen considered as the experimental unit, body weight as blocking factor, and treatment as a fixed effect with 10 replicates/treatment. Overall final BW and ADG were greater for pigs fed SBM, Val, and Ile diets than the NC with PC and Trp intermediate. Pigs fed the Val diet had greater (R< 0.05) ADFI than the NC with pigs fed SBM, PC, Ile, and Trp intermediate. No differences were detected between treatments for G:F. In conclusion, increasing Val or Ile in high Lys-HCl-DDGS-based diets improved growth performance and final BW compared with pigs fed diets containing high levels of HCl-Lys without added Val and Ile. These results demonstrate that negative effects of high Leu in corn-DDGS-based diets can be overcome by increasing the ratios of Val and Ile to Lys.

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205 Dietary Strategies to Limit Average Daily Gain of Late Finishing Pigs

Journal of Animal Science ◽

10.1093/jas/skab054.107 ◽

2021 ◽

Vol 99 (Supplement_1) ◽

pp. 64-64

Author(s):

Devin Goehring ◽

Katherine A McCormick ◽

Julie Mahoney ◽

Rodney Hinson

Keyword(s):

Mixed Model ◽

Linear Mixed Model ◽

Block Design ◽

Average Daily Gain ◽

Finishing Pigs ◽

Compensatory Gain ◽

And Gender ◽

Dietary Treatments ◽

Dietary Strategies ◽

Daily Gain

Abstract A total of 2,164 pigs [DNA610 x DNA241; initially 100.7 ± 2.14 kg body weight (BW)] were used in a 54.1 ± 3.85-day study to determine dietary strategies to limit average daily gain (ADG) in late finishing pigs raised in a commercial environment. Mixed-sex pens (20.0 ± 0.85 pigs/pen) balanced by initial BW and gender ratio were randomly assigned to 1 of 4 dietary treatments fed ad libitum with 27 replications each: (1) Nutritionally replete corn soybean-meal control (CTRL), (2) Treatment 1 with 21% reduced lysine and other amino acids (AAR), (3) Corn/vitamin/mineral diet (CVM), and (4) Treatment 3 fed for 21 days then switched to CTRL. Data were analyzed as a randomized complete block design using a linear mixed model. Relative to CTRL, feeding AAR or CVM for 21 days reduced ADG (P < 0.001), average daily feed intake (ADFI; P = 0.005), and gain-to-feed (G:F, P < 0.001). Over 55-days, AAR and CVM diets reduced (P < 0.001) cumulative ADG, ADFI, G:F, and final BW compared to CTRL. Transitioning to CTRL diet from CVM diet after 21-days increased ADG (P < 0.001) and improved G:F (P < 0.001) from day 21 to marketing compared to 55-day CTRL, AAR, and CVM; nevertheless, the compensatory CTRL period was insufficient for the 21-day CVM fed pigs to fully compensate resulting in reduced cumulative BW, ADG (P < 0.001) and poorer G:F (P < 0.001) than the 55-day CTRL. All holding strategies decreased (P < 0.001) carcass yield, hot carcass weight (HCW), and loin depth compared to CTRL. Utilizing a CVM diet for 21 or 55 days increased (P < 0.001) backfat compared to CTRL or AAR. In summary, utilizing lysine deficient or corn/vitamin/mineral diets can limit ADG along with poorer G:F. Transitioning to a non-holding diet after feeding a corn/vitamin/mineral diet for 21-days resulted in compensatory gain, but reductions in growth performance and carcass traits remained evident.

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73 Effects of dietary neutral detergent fiber and standardized ileal digestible lysine levels on growth performance and carcass characteristics of growing-finishing pigs

Journal of Animal Science ◽

10.1093/jas/skaa054.103 ◽

2020 ◽

Vol 98 (Supplement_3) ◽

pp. 57-58

Author(s):

Uislei Orlando ◽

Ning Lu ◽

Carine Vier ◽

Wayne Cast ◽

Xun Zhou ◽

...

Keyword(s):

Growth Performance ◽

Block Design ◽

Average Daily Gain ◽

Neutral Detergent Fiber ◽

Feed Ratio ◽

Experimental Unit ◽

Finishing Pigs ◽

Dietary Treatments ◽

Daily Gain ◽

Standardized Ileal Digestible Lysine

Abstract Our objective was to determine the effects of feeding different neutral detergent fiber (NDF) and standardized ileal digestible (SID) lysine (Lys) levels on performance of growing-finishing pigs from 30- to 130-kg. A total of 2,016 barrows and gilts (PIC 280×Camborough, initial BW of 29.6±0.53 kg) were allotted to a randomized complete block design with a 2×2 factorial arrangement. Dietary treatments (Table 1) consisted with two NDF levels (13% or 20%) and two SID Lys curves (PIC2008 or PIC2016). There were 21 mixed-sex pigs per pen, and 24 pens per treatment. The experiment diets were fed in 3 phases. Wheat, wheat by-products, peas, and canola oil were used with NRC (2012) loading values to achieve treatments, and all diets were formulated to be iso-caloric (2,420 kcal NE/kg). Experimental data were analyzed using generalized linear mixed models with pen as the experimental unit. Increasing NDF level resulted in a reduction (P< 0.05) in average daily gain (ADG), average daily feed intake, hot carcass weight, carcass yield, carcass ADG, and backfat depth (Table 2), and tended to decrease percentage of removals and mortality (P=0.10). Pigs fed PIC2016 Lys curve had greater ADG and carcass ADG as compared to those fed PIC2008 Lys curve (P< 0.05). There were NDF×Lys interactions (P< 0.10) for ADG, gain to feed ratio (G:F), carcass ADG, and carcass G:F. These response criteria were improved for pigs fed PIC2016 Lys curve compared to those fed PIC2008 Lys curve when NDF level was 13%; while no evidence of differences was observed at 20% NDF. Results indicate that increasing NDF level from 13 to 20% deteriorate performance of 30- to 130- kg pigs; and the improved growth performance of pigs fed PIC2016 Lys curve as compared to those fed PIC2008 Lys curve was only observed when lower NDF level was presented.

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THE PERFORMANCE AND THIAMIN STATUS OF PIGS FED SULFUR DIOXIDE TREATED HIGH-MOISTURE BARLEY

Canadian Journal of Animal Science ◽

10.4141/cjas87-087 ◽

1987 ◽

Vol 67 (3) ◽

pp. 841-854 ◽

Cited By ~ 7

Author(s):

D. M. GIBSON ◽

J. J. KENNELLY ◽

F. X. AHERNE

Keyword(s):

Sulfur Dioxide ◽

Feed Intake ◽

Average Daily Gain ◽

Finishing Pigs ◽

High Moisture ◽

Liquid Sulfur ◽

Toxicological Effects ◽

Diet Mixing ◽

Dietary Treatments ◽

Daily Gain

High-moisture barley (HMB) was ensiled or treated with 1% (wt/wt) liquid sulfur dioxide (SO2). Forty-five weanling pigs were allocated to five dietary treatments for 28 d. Diets consisted of: (1) dry barley, diet mixed every 28 d; (2) ensiled HMB, diet mixed daily; (3) SO2-treated HMB, diet mixed every 28 d; (4) SO2-treated HMB, diet mixed daily; (5) SO2-treated HMB, diet mixed daily and supplemented with thiamin. All diets contained 47% barley on a dry matter (DM) basis. Pigs fed diets 2 and 4 continued on test to 85 kg; diets formulated after 28 d contained 75% barley (DM basis). Feed intake, growth rate and feed:gain ratio were not influenced (P < 0.05) by treatment during the 28-d initial trial. For pigs fed SO2-treated HMB to 85 kg, feed intake and average daily gain were reduced by 9.8 and 9.0%, respectively. SO2 treatment effectively preserved high-moisture barley for 18 d at 16 °C; however, 61% of the dietary thiamin was destroyed by 7 d after diet mixing. Pigs fed diet 4 were thiamin depleted at slaughter; with a 38.5% higher erythrocyte thamin pyrophosphate effect, an 83% incidence of cardiac hypertrophy and thiamin levels in meat reduced to 7.6% of that present in the meat of pigs fed untreated HMB. Destruction of dietary thiamin appears to have been the primary factor responsible for reduced animal performance. Reduced ration palatability and toxicological effects on the digestive tract due to 75% SO2 treated grain in the diet (DM basis) may have also contributed to the reduced performance of growing-finishing pigs. Key words: Sulfur dioxide, preservative, barley, pigs, thiamin

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PSIV-9 Effect of carbohydrases on growth performance, nutrient digestibility, blood profiles and fecal microbiota in weanling pigs fed reduced energy diet

Journal of Animal Science ◽

10.1093/jas/skz122.316 ◽

2019 ◽

Vol 97 (Supplement_2) ◽

pp. 179-180

Author(s):

Jemin Ahn ◽

Xiang Ao ◽

Haoyang Sun ◽

In Ho Kim

Keyword(s):

Growth Performance ◽

Average Daily Gain ◽

Fecal Microbiota ◽

Nutrient Digestibility ◽

Negative Effects ◽

Weanling Pigs ◽

Gross Energy ◽

Dietary Treatments ◽

Daily Gain ◽

Blood Profiles

Abstract This study was conducted to evaluate the effects of carbohydrases on growth performance, nutrient digestibility, blood profiles and fecal microbiota in weanling pigs fed reduced energy diet. A total of 160 cross-bred [(Yorkshire × Landrace) × Duroc)] weanling pigs with an initial BW of 7.23 ± 1.08 kg were used in this 42-day trial. Pigs were randomly allocated in 1 of the following 4 dietary treatments: (1) PC, positive diet (NE 2,545 kcal/kg); (2) NC, negative diet (NE 2470 kcal/kg); (3) NC1, NC + 0.1% carbohydrases; (4) NC2, NC + 0.2% carbohydrases based on the sex and BW. There were 8 replications (pens) per treatment with 5 pigs per pen. During d 0-7, pigs fed NC diet had lower (P < 0.05) average daily gain (ADG) and average daily feed intake (ADFI) than those fed PC and NC2 diets. NC group reduced (P < 0.05) ADG throughout the experiment compared with PC and NC2 groups. NC group reduced (P < 0.05) the digestibility of dry matter, nitrogen and gross energy. Taken together, reduced energy diet caused detrimental effects on growth performance and nutrient digestibility in weanlings, while the addition of carbohydrases (0.2%) can partially counteract these negative effects.

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Effect of choline chloride with propylene glycol on growth performance, and meat quality in finishing pigs

Indian Journal of Animal Research ◽

10.18805/ijar.b-922 ◽

2018 ◽

Author(s):

Yang Jiao ◽

Sang In Lee ◽

In Ho Kim

Keyword(s):

Body Weight ◽

Growth Performance ◽

Propylene Glycol ◽

Meat Quality ◽

Choline Chloride ◽

Average Daily Gain ◽

Finishing Pigs ◽

Basic Diet ◽

Dietary Treatments ◽

Daily Gain

This study was conducted to evaluate the effect of choline chloride alone and in combination with propylene glycol on the growth performance, meat quality and backfat in finishing pigs. A total of 90 crossbred ((Landrace× Yorkshire)× Duroc) pigs with an average initial body weight (BW) of 75.15± 1.94 kg were randomly distributed by BW and sex. This 8-week experiment consisted of 3 dietary treatments with 6 replications per treatment and 5 pigs per pen. The experiment included 3 treatments: CON, basic diet; TRT1, basic diet+0.05% choline chloride; TRT2, basic diet+0.05% biocholine P (chloride chloride and propylene glycol). Body weight was statistically higher (P less than 0.05) in pigs fed TRT2 diet than the CON diet in week 8. During 4 to 8 weeks and overall, the average daily gain (ADG) was significant higher (P less than 0.05) in the pigs fed TRT2 diet than the CON diet. Digestibility of nitrogen was significantly increased (P less than 0.05) at week 4 and week 8, back fat was higher (P less than 0.05) in week 6 and week 8 in pigs fed TRT2 diet than the CON diet. In conclusion, dietary TRT2 can increase the BW, ADG, nitrogen, and backfat in finishing pigs.

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142 Evaluation of Proso Millet as a Partial or Complete Replacement for Corn in Growing-finishing Diets for Pigs

Journal of Animal Science ◽

10.1093/jas/skab054.117 ◽

2021 ◽

Vol 99 (Supplement_1) ◽

pp. 71-72

Author(s):

Khang A Nguyen ◽

Melanie D Trenhaile-Grannemann ◽

Thomas Burkey ◽

Phillip Miller

Keyword(s):

Growth Performance ◽

Soybean Meal ◽

Block Design ◽

Average Daily Gain ◽

Experimental Unit ◽

Finishing Pigs ◽

Complete Replacement ◽

Proso Millet ◽

Dietary Treatments ◽

Daily Gain

Abstract An experiment was conducted to evaluate the effects of increasing the inclusion of proso millet on the growth performance of growing and finishing pigs. Using a randomized complete block design, 36 crossbred barrows, with an average initial weight of 22.2 kg, were randomly assigned to 1 of 4 dietary treatments (9 pens/treatment; 1 pig/pen). Diet 1 was corn-soybean meal-based (control) and Diets 2, 3, and 4 had proso millet replacing 33%, 67%, and 100%, respectively, of corn in the control diet. The diets were formulated according to 4 growth phases (P1, 25 to 50 kg BW; P2, 50 to 75 kg BW; P3, 75 to 100 kg BW; and P4, 100 to 135 kg BW) with nutrient contents formulated according to NRC (2012) recommendations. Data were analyzed using the GLIMMIX procedure of SAS, using pig as the experimental unit. In P1 and P2, no differences in average daily gain (ADG) or average daily feed intake (ADFI) were observed among treatments (P > 0.3). In P3, pigs consuming the proso millet diets had greater ADFI than pigs consuming the basal diet, especially pigs fed Diet 4 compared to pigs fed Diet 1 (3.66 vs. 3.29 kg; P < 0.01). The ADG:ADFI ratio was not affected (P > 0.1) by treatments during this period. In P4, although there was a difference in ADFI between pigs fed Diet 3 and Diet 1 (3.8 vs. 3.47 kg; P = 0.04), no decreases in ADG:ADFI ratio were observed among the four dietary treatments (P > 0.5). Average daily gain was not affected (P > 0.3) by treatments during the growing-finishing period, suggesting that the level of corn replacement up to 100% by proso millet did not affect pig growth. In conclusion, proso millet was shown to effectively replace corn in corn-soybean meal-based diet for growing-finishing pigs without compromising growth performance.

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Additional nutritional considerations for preconditioning beef calves.

EDIS ◽

10.32473/edis-an334-2017 ◽

2017 ◽

Vol 2017 (4) ◽

Author(s):

Philipe Moriel

Keyword(s):

Average Daily Gain ◽

Beef Steers ◽

Labor Costs ◽

Vaccine Response ◽

Negative Effects ◽

Beef Calves ◽

Supplemental Feed ◽

Concentrate Supplementation ◽

Protein Supply ◽

Daily Gain

Calves can be preconditioned using a wide variety of supplemental feed ingredients. However, feed ingredient selection is not the only factor to consider during a preconditioning process. Increasing the protein supply to stressed, preconditioning beef steers led to greater growth performance, and increased immune response to vaccination during a 42-day preconditioning period. Producers should not reduce the frequency of concentrate supplementation during the entire preconditioning period as it might lead to poorer vaccine response and average daily gain (consequently, less calf value at sale). However, a gradual reduction of frequency of supplementation is a supplementation strategy that can overcome these negative effects on growth and immunity, and allows producers to save on feeding and labor costs without producing lighter calves that have weaker immune responses.

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Effects of Fumonisin-Contaminated Corn on Growth Performance of 9 to 28 kg Nursery Pigs

Toxins ◽

10.3390/toxins12090604 ◽

2020 ◽

Vol 12 (9) ◽

pp. 604

Author(s):

Zhong-Xing Rao ◽

Mike D. Tokach ◽

Jason C. Woodworth ◽

Joel M. DeRouchey ◽

Robert D. Goodband ◽

...

Keyword(s):

Growth Performance ◽

Linear Response ◽

Animal Feed ◽

Average Daily Gain ◽

Fumonisin B1 ◽

Nursery Pigs ◽

Feed Production ◽

Dietary Treatments ◽

Daily Gain ◽

Effect Of Feeding

Fumonisin contamination in corn is an emerging issue in animal feed production. Fumonisin disrupts the metabolism of sphingolipids and reduces growth performance. This experiment was conducted to determine the effect of feeding fumonisin-contaminated corn on growth performance and sphinganine (SA) to sphingosine (SO) ratios of 9 to 28 kg pigs. A total of 350 pigs, were used with 5 pigs/pen and 14 pens/treatment. Dietary treatments contained fumonisin-contaminated corn (50 mg/kg of fumonisin B1 + B2) blended with low fumonisin corn (10 mg/kg of fumonisin B1 + B2) to provide dietary fumonisin concentrations of 7.2, 14.7, 21.9, 32.7, and 35.1 mg/kg. From day 0 to 28, increasing fumonisin concentration decreased (linear, p < 0.001) average daily gain, average daily feed intake (linear, p = 0.055), and gain:feed ratio (linear, p = 0.016). Although these response criteria tested linear, the greatest reduction in performance was in pigs fed with 32.7 and 35.1 mg/kg of fumonisin (B1 + B2). Increasing fumonisin concentration increased the serum SA:SO ratio (linear, p < 0.001) on day 14 and 28. In summary, for 9 to 28 kg nursery pigs, increasing fumonisin linearly decreased average daily gain and gain:feed ratio. However, despite the linear response, diets containing up to 21.9 mg/kg of fumonisin did not have as dramatic a decrease in growth performance as those fed more than 32.7 mg/kg. Further research is warranted to determine the effect of fumonisin concentrations between 21.9 and 32.7 mg/kg.

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