357 Effect of Energy Supplementation on Growth, Health, and Carcass Traits of Pasture-raised Lambs

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 199-200
Author(s):  
Amanda M Grev ◽  
Susan Schoenian ◽  
Jeffery W Semler ◽  
Dahlia O’Brien
Keyword(s):  
Statistical Significance ◽  
Carcass Traits ◽  
Failure To Thrive ◽  
Individual Performance ◽  
Additional Time ◽  
Treatment Groups ◽  
Acclimation Period ◽  
Limiting Nutrient ◽  
Energy Supplementation ◽  
The Cost

Abstract Energy is often the most limiting nutrient in pasture diets. The effect of energy supplementation on the growth, health, and carcass traits of pasture-raised lambs was investigated. Seventy-nine Katahdin ram lambs were delivered to the Western Maryland Research & Education Center on June 15. After an 11-d acclimation period, lambs were allocated to two treatment groups based on age, weight, birth type, and FEC. Lambs in the PASTURE group (n = 40) rotationally grazed 2 ha of high quality, mixed pasture for 102 d. Lambs in the SUPPL group (n = 39) grazed similar pastures and were hand-fed a daily energy supplement (450 g of whole barley). The groups were handled bi-weekly to determine body weights, FAMACHA©, BCS, and dag scores. Individual fecal samples were collected upon arrival and at two additional time points. Lambs were ultrasound scanned on Sept 25 to determine carcass traits. Data were analyzed using the MIXED procedure of SAS, with statistical significance set at P ≤ 0.05. ADG varied considerably among weigh periods. Standard deviations were typically quite large, indicating wide variation in individual performance. Overall, the SUPPL lambs had higher ADG (P < 0.01), more backfat (P < 0.03), and higher BCS (P < 0.01) than the PASTURE lambs. There were no statistical differences in starting weight, ending weight, and loin depth. While internal parasites were not a problem during the study (only one lamb had a FAMACHA© score >4), PASTURE lambs had lower FEC (P < 0.05) on August 17 (240 ± 81 vs. 468 ± 80 epg). The value of additional gain (0.9 kg) would not have covered the cost of feed; however, four lambs were removed from the PASTURE group (due to death or failure to thrive) whereas only two lambs were removed from the SUPPL group. The study will be repeated in 2021 with similar lambs and protocol.

scholarly journals EXPRESS: Efficacy and Safety of Tadalafil in a Pediatric Population with Pulmonary Arterial Hypertension: Phase 3 randomized, Double Blind Placebo-Controlled Study

2021 ◽  
pp. 204589402110249
Author(s):  
David D Ivy ◽  
Damien Bonnet ◽  
Rolf MF Berger ◽  
Gisela Meyer ◽  
Simin Baygani ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Statistical Significance ◽  
Significance Testing ◽  
Efficacy And Safety ◽  
Phase 3 ◽  
Statistical Significance Testing ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Treatment Groups ◽  
Pulmonary Arterial

Objective: This study evaluated the efficacy and safety of tadalafil in pediatric patients with pulmonary arterial hypertension (PAH). Methods: This phase-3, international, randomized, multicenter (24 weeks double-blind placebo controlled period; 2-year, open-labelled extension period), add-on (patient’s current endothelin receptor antagonist therapy) study included pediatric patients aged <18 years with PAH. Patients received tadalafil 20 mg or 40 mg based on their weight (Heavy-weight: ≥40 kg; Middle-weight: ≥25—<40 kg) or placebo orally QD for 24 weeks. Primary endpoint was change from baseline in 6-minute walk (6MW) distance in patients aged ≥6 years at Week 24. Sample size was amended from 134 to ≥34 patients, due to serious recruitment challenges. Therefore, statistical significance testing was not performed between treatment groups. Results: Patient demographics and baseline characteristics (N=35; tadalafil=17; placebo=18) were comparable between treatment groups; median age was 14.2 years (6.2 to 17.9 years) and majority (71.4%, n=25) of patients were in HW cohort. Least square mean (SE) changes from baseline in 6MW distance at Week 24 was numerically greater with tadalafil versus placebo (60.48 [20.41] vs 36.60 [20.78] meters; placebo-adjusted mean difference [SD] 23.88 [29.11]). Safety of tadalafil treatment was as expected without any new safety concerns. During study period 1, two patients (1 in each group) discontinued due to investigator’s reported clinical worsening, and no deaths were reported. Conclusions: The statistical significance testing was not performed between the treatment groups due to low sample size, however, the study results show positive trend in improvement in non invasive measurements, commonly utilized by clinicians to evaluate the disease status for children with PAH. Safety of tadalafil treatment was as expected without any new safety signals.

scholarly journals Cold atmospheric plasma coupled with air abrasion in liquid medium for the treatment of peri-implantitis model grown with a complex human biofilm: an in vitro study

2021 ◽  
Author(s):  
Wang Lai Hui ◽  
Vittoria Perrotti ◽  
Adriano Piattelli ◽  
Kostya (Ken) Ostrikov ◽  
Zhi Fang ◽  
...  
Keyword(s):  
Liquid Medium ◽  
Statistical Significance ◽  
Atmospheric Plasma ◽  
Air Abrasion ◽  
Implant Surface ◽  
Cold Atmospheric Plasma ◽  
Surface Features ◽  
Treatment Groups ◽  
Surface Decontamination

Abstract Objective Treatment of implants with peri-implantitis is often unsuccessful due to residual microbial biofilm hindering re-osseointegration. The aim of this study was to treat biofilm-grown titanium (Ti) implants with different modalities involving air abrasion (AA) and cold atmospheric plasma (CAP) to compare the effectiveness in surface decontamination and the alteration/preservation of surface topography. Materials and methods Saliva collected from a peri-implantitis patient was used to in vitro develop human biofilm over 35 implants with moderately rough surface. The implants were then mounted onto standardized acrylic blocks simulating peri-implantitis defects and treated with AA (erythritol powder), CAP in a liquid medium, or a combination (COM) of both modalities. The remaining biofilm was measured by crystal violet (CV). Surface features and roughness before and after treatment were assessed by scanning electron microscope (SEM). The data were statistically analyzed using Kruskal-Wallis followed by Tukey’s multiple comparison test. Results In the present peri-implantitis model, the human complex biofilm growth was successful as indicated by the statistical significance between the negative and positive controls. All the treatment groups resulted in a remarkable implant surface decontamination, with values very close to the negative control for AA and COM. Indeed, statistically significant differences in the comparison between the positive control vs. all the treatment groups were found. SEM analysis showed no post-treatment alterations on the implant surface in all the groups. Conclusions Decontamination with AA delivering erythritol with or without CAP in liquid medium demonstrated compelling efficacy in the removal of biofilm from implants. All the tested treatments did not cause qualitative alterations to the Ti surface features. No specific effects of the CAP were observed, although further studies are necessary to assess its potential as monotherapy with different settings or in combination with other decontamination procedures. Clinical relevance CAP is a promising option in the treatment of peri-implantitis because it has potential to improve the elimination of bacterial plaque from implant surfaces, in inaccessible pockets or during open-flap debridement, and should stimulate the process of the re-osseointegration of affected dental implants by not altering surface features and roughness.

scholarly journals Penggunaan Musik Daerah Untuk Meningkatkan Kompetensi Kecepatan Dan Ketepatan Mengetik Mahasiswa

2017 ◽  
Vol 2 (3) ◽  
pp. 12
Author(s):  
Maya Setiawardani ◽  
Tintin Suhaeni
Keyword(s):  
Instrumental Music ◽  
Traditional Music ◽  
Individual Performance ◽  
Control Group ◽  
Treatment Groups ◽  
Average Value ◽  
Typing Skills ◽  
Regional Music ◽  
Almost All ◽  
And Control

Mastery of keyboarding being part urgent to communicate through the computer, and very important, especially students who study in the field of business. On the other side, individual performance also influenced by the work environment, and music is one form the environment that could effect keyboarding performance. A model that can describe this is the stimulus-responsible model of mehrabian-russell which explains that music can affect the performance of individual writing. Almost all of Indonesia has traditional music. Therefore, research is needed to identify the effects of traditional music to enrich the area of innovation in strategies and techniques of learning keyboarding skills. In this study conducted an experiment on two groups, the treatment groups(traditional music) and control group (without traditional) and questionnaire to strengthen the experimental results. In preliminary tests of typing, both groups had a mean AWPM identical or similar. Furthermore, tests carried one, where the treatment group listened to five kinds of music Java, Sunda, and Bali. The test result and the result of the questionnaire showed that (typing skills shown by the average value of AWPM) will increase significantly used of traditional music as the background. So, the genre of traditional music can be stimulant to improve average performance of AWPM. There are three traditional kinds of music that can improve student typing speed and accuracy significantly, a regional music cublek-cublek suweng, kebiar bali, and oleg tambuliningan, but cublek-cublek suweng is a genre of traditional music that has the best effect. Therefore, the process of learning courses keyboarding skills needs to use instrumental traditional music, especially instrumental music that has a fast and cheerfully tempo.

scholarly journals Analgesic effect and side effects of celecoxib and meloxicam in canine hip osteoarthritis

2014 ◽  
pp. 4289-4300 ◽  
Author(s):  
Víctor Molina D ◽  
David Álzate V ◽  
Jhon Ruíz B ◽  
Manuela Urrea A ◽  
Juan Tobón J
Keyword(s):  
Chronic Gastritis ◽  
Treatment Initiation ◽  
Statistical Significance ◽  
Hip Osteoarthritis ◽  
Treatment Groups ◽  
Toxicological Effects ◽  
Tukey Test ◽  
Coagulation Tests ◽  
Gastric Endoscopy ◽  
Articular Pain

ABSTRACTObjective. To evaluate the pharmacological, clinical and toxicological effects of celecoxib and meloxicam for analgesia for 30 days in dogs with hip osteoarthritis. Materials and methods. Twenty-four patients were evaluated, 75% were females with an average age of 7.16 ± 2.06 years and twenty five percent were males with an average age of 7.83 ± 2.22 years. All patients had hip osteoarthritis and they were randomized into two groups; one group received oral celecoxib 5 mg/kg every 12 hours during one month and the second group received oral meloxicam 0.2 mg/kg every 24 hours during 1 month. The patients were evaluated for analgesia, and hematological, renal, liver, and coagulation tests on days 0, 10th and 30th after treatment initiation, and a gastric endoscopy on day 30. Statistical analysis was performed using a HSD Tukey test and c2 with a 5% level of statistical significance. Results. Both drugs reduced articular pain according to the Melbourne scale during the 30 days of treatment (p≤0.05). Hematological, renal, hepatic and coagulation tests were normal in both treatment groups. All patients presented chronic gastritis on endoscopy on day 30th. Conclusions. Both drugs decreased pain at day 30th without causing alterations in hematological, renal, hepatic or coagulation tests after 30 days of treatment. However, both drugs induced chronic gastritis.

scholarly journals Mosquito Larvae Detection using Deep Learning

2019 ◽  
Vol 8 (12) ◽  
pp. 804-809
Keyword(s):  
Deep Learning ◽  
Mobile Application ◽  
Web Application ◽  
Individual Performance ◽  
Mosquito Larvae ◽  
Accuracy Score ◽  
Performance Category ◽  
Training Time ◽  
The Cost ◽  
And Training

Dengue cases has become endemic in Malaysia. The cost of operation to exterminate mosquito habitats are also high. To do effective operation, information from community are crucial. But, without knowing the characteristic of Aedes larvae it is hard to recognize the larvae without guide from the expert. The use of deep learning in image classification and recognition is crucial to tackle this problem. The purpose of this project is to conduct a study of characteristics of Aedes larvae and determine the best convolutional neural network model in classifying the mosquito larvae. 3 performance evaluation vector which is accuracy, log-loss and AUC-ROC will be used to measure the model’s individual performance. Then performance category which consist of Accuracy Score, Loss Score, File Size Score and Training Time Score will be used to evaluate which model is the best to be implemented into web application or mobile application. From the score collected for each model, ResNet50 has proved to be the best model in classifying the mosquito larvae species.

Fatty acid profile, carcass traits and meat quality of Nellore steers following supplementation with various lipid sources

2017 ◽  
Vol 57 (6) ◽  
pp. 1170 ◽  
Author(s):  
Isabela P. C. Carvalho ◽  
Giovani Fiorentini ◽  
Josiane F. Lage ◽  
Juliana D. Messana ◽  
Roberta. C. Canesin ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Dietary Supplements ◽  
Meat Quality ◽  
Linseed Oil ◽  
Statistical Significance ◽  
Average Daily Gain ◽  
Carcass Traits ◽  
Subcutaneous Fat ◽  
Practical Significance

The aim of the present study was to evaluate the fatty acid composition of meat and subcutaneous fat, carcass traits and meat quality of Nellore steers fed diets supplemented with various lipid sources. Forty-five young bulls, with average bodyweight of 441 ± 30 kg, were allotted into 10 paddocks, with five treatments, each consisting of two paddocks. The bulls were randomly assigned into one of the following five treatments, which consisted of four lipid sources: palm oil (PO), linseed oil, rumen protected fat (soybean-based oil), whole soybean, and a control (without additional fat). Trial duration was 120 days, which included 30 days of adaptation. Supplements were offered daily at 10 g/kg bodyweight per day. Dietary supplements for providing additional fat were formulated to consist of 10% ether extract. Lipid sources did not significantly affect the average daily gain (P = 0.797) or dressing percentage (P = 0.663). Supplementation with PO increased the concentrations of lauric acid (P = 0.036) and myristic acid (P < 0.001) in the muscle and subcutaneous fat. Animals supplemented with linseed oil had significantly higher concentrations of conjugated linolenic acid in the meat (P = 0.036) and fat (P = 0.049) than did control animals. In the present study, the use of various lipid sources in dietary supplements of grazing cattle during finishing period did not affect carcass traits or physical attributes of beef. This absence of statistical significance may be related to the minimum number of repeat paddocks (2) per treatment. Thus, differences that can have a practical significance were not evidenced by statistical analysis. The inclusion of PO and protected fatty acids derived from soybean oil (rumen-protected fat) is not recommended as a method to improve the lipid profile of meat and subcutaneous fat of Nellore cattle.

The effect of immunocastration 7 weeks before slaughter on the behaviour, growth and meat quality of post-pubertal bulls

1999 ◽  
Vol 68 (1) ◽  
pp. 163-171 ◽  
Author(s):  
J. G. Jago ◽  
L. R. Matthews ◽  
T. E. Trigg ◽  
P. Dobbie ◽  
J. J. Bass
Keyword(s):  
Meat Quality ◽  
Active Immunization ◽  
Plasma Testosterone ◽  
Primary Immunization ◽  
Single Treatment ◽  
Growth Behaviour ◽  
Treatment Groups ◽  
Colour Measurements ◽  
The Cost

AbstractActive immunization against gonadotropin-releasing hormone (GnRH), commonly known as immunocastration, has been proposed as an alternative to traditional methods of castrating bulls. This study evaluated the effects of immunocastration on growth, behaviour and meat quality of post-pubertal bulls. Bulls were either vaccinated against GnRH (no. = 30, I) or left intact (no. = 30, B). A third treatment consisted of steers (no. = 20, S) that had been castrated pre-pubertally. The animals were run in eight single treatment groups (no. = 10 per group), three of each of В and I and two groups of S. Anti-GnRH antibodies developed and plasma testosterone concentrations declined in I following immunization. Aggressive behaviour of I declined to be lower (P < 0·5) than B and no different from S, 5 weeks after primary immunization. Seven weeks after immunocastration all animals were slaughtered. The hot carcass weight of I was between that of B and S but not significantly different from either. There were no effects of treatment on pHu or meat colour measurements. Taste panel assessment rated I higher than B, but lower than S for tenderness, juiciness and overall palatability. These results demonstrate that immunocastration of post-pubertal bulls 7 weeks before slaughter is a potential means of reducing problematic bull behaviour and improving meat quality although this is likely to be at the cost of reduced weight gain.

scholarly journals 149 Interaction of dietary protein and endophyte- infected Tall Fescue seed in stocker steers on finishing phase performance and carcass traits

2019 ◽  
Vol 97 (Supplement_1) ◽  
pp. 38-39
Author(s):  
Matthew E Davis ◽  
Rebecca K Poole ◽  
Matthew H Poore ◽  
Daniel H Poole ◽  
Carrie L Pickworth
Keyword(s):  
Dietary Protein ◽  
Statistical Significance ◽  
Ergot Alkaloids ◽  
Carcass Characteristics ◽  
Fescue Toxicosis ◽  
Phase Growth ◽  
Treatment Groups ◽  
Background Period ◽  
Quality Grade ◽  
To Receive

Abstract Fescue toxicosis is a multifaceted disease that negatively impacts cattle. It was hypothesized that exposure to endophyte-infected fescue during the stocker phase affects finishing phase growth and carcass characteristics. Eight-month-old steers were sorted by weight and randomly assigned to receive one of four treatments for 56 days in confinement: endophyte-free seed (0 ug/ kg ergovaline) with either 18% (EF-18; n = 9) or 14% dietary protein (EF-14; n = 9) and endophyte-infected seed (500 ug/kg ergovaline) with 18% (EI-18; n = 9) or 14% dietary protein (EI-14; n = 9). Following fescue exposure calves were backgrounded on novel endophyte fescue pastures for 8 mo. At 18 mo, all steers were vaccinated, implanted, and reentered the feedlot for a 112 d growing phase and 52 d finishing phase. Body weight was recorded every 28 d and carcass data was collected at slaughter. Data were analyzed using the MIXED procedure of SAS for effects of BW, ADG, dressing percentage (DP), HCW, backfat, ribeye area (REA), KPH, USDA Yield grade (YG), and USDA Quality grade (QG). Statistical significance was determined at P > 0.05) HCW, BW, backfat, REA, DP, or QG. TheEI-14 had a greater ADG (1.69 kg/d) during the feedlot growing phase compared to the other treatment groups (1.53, 1.47, 1.55 for EI-18, EF-14, EF-18, respectively; P > 0.05). Steers stockered on 18% dietary protein had greater BW compared to steers previously fed at 14% (501.3±3.8 vs. 489.7±3.8; P = 0.0339). In addition, 18% protein in stocker diet resulted in greater KPH (2.3±0.2 vs. 1.78±0.2; P = 0.0129) and YG (3.4±0.1 vs. 3.0±0.1; P = 0.0168) compared with steers fed 14% dietary protein. Finishing growth and carcass characteristics were not affected by exposure to ergot alkaloids at weaning as much as dietary protein when cattle had a background period prior to feedlot entry

scholarly journals Electroacupuncture with Usual Care for Patients with Non-Acute Pain after Back Surgery: Cost-Effectiveness Analysis Alongside a Randomized Controlled Trial

2020 ◽  
Vol 12 (12) ◽  
pp. 5033
Author(s):  
NamKwen Kim ◽  
Kyung-Min Shin ◽  
Eun-Sung Seo ◽  
Minjung Park ◽  
Hye-Yoon Lee
Keyword(s):  
Cost Effectiveness ◽  
Usual Care ◽  
Societal Perspective ◽  
National Health ◽  
Controlled Trial ◽  
Statistical Significance ◽  
Acute Low Back Pain ◽  
Life Years ◽  
Back Surgery ◽  
The Cost

Electroacupuncture (EA) is used to treat pain after back surgery. Although this treatment is covered by national health insurance in Korea, evidence supporting its cost-effectiveness and contribution to the sustainability of the national health care system has yet to be published. Therefore, an economic evaluation, alongside a clinical trial, was conducted to estimate the cost-effectiveness of EA and usual care (UC) versus UC alone to treat non-acute low back pain (LBP). In total, 108 patients were recruited and randomly assigned to treatment groups; 106 were included in the final cost utility analysis. The incremental cost-effectiveness ratio of EA plus UC was estimated as 7,048,602 Korean Rate Won (KRW) per quality-adjusted life years (QALYs) from the societal perspective (SP). If the national threshold was KRW 30 million per QALY, the cost-effectiveness probability of EA plus UC was an estimated 85.9%; and, if the national threshold was over KRW 42,496,372 per QALY, the cost-effectiveness probability would be over 95% percent statistical significance. Based on these results, EA plus UC combination therapy for patients with non-acute LBP may be cost-effective from a societal perspective in Korea.

scholarly journals Pharyngeal Detection of Staphylococcus aureus as a Possible Factor Related to Disgust Sensitivity in Humans

2020 ◽  
Vol 17 (21) ◽  
pp. 8286
Author(s):  
Agnieszka Żelaźniewicz ◽  
Judyta Nowak-Kornicka ◽  
Renata Figura ◽  
Agata Groyecka-Bernard ◽  
Piotr Sorokowski ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Statistical Significance ◽  
Disgust Sensitivity ◽  
Significance Level ◽  
Body Adiposity ◽  
Behavioral Avoidance ◽  
Sexual Disgust ◽  
Scale Levels ◽  
The Difference ◽  
The Cost

Disgust triggers behavioral avoidance of pathogen-carrying and fitness-reducing agents. However, because of the cost involved, disgust sensitivity should be flexible, varying as a function of an individual’s immunity. Asymptomatic colonization with Staphylococcus aureus often results from weakened immunity and is a potential source of subsequent infections. In this study, we tested if pharyngeal colonization with S. aureus, evaluated based on a single swab collection, is related to an individual’s disgust sensitivity, measured with the Three Domain Disgust Scale. Levels of immunomodulating hormones (cortisol and testosterone), general health, and body adiposity were controlled. Women (N = 95), compared to men (N = 137), displayed higher sexual disgust sensitivity, but the difference between individuals with S. aureus and without S. aureus was significant only in men, providing support for prophylactic hypothesis, explaining inter-individual differences in disgust sensitivity. Men (but not women) burdened with asymptomatic S. aureus presence in pharynx exhibit higher pathogen disgust (p = 0.04) compared to individuals in which S. aureus was not detected. The positive relationship between the presence of the pathogen and sexual disgust was close to the statistical significance level (p = 0.06), and S. aureus colonization was not related with moral disgust domain.

Sign in / Sign up

Export Citation Format

Share Document