PSX-B-24 Influence of the immunomodulatory drug Azoxivet on the post-vaccination immune response in laying hens

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 269-269
Author(s):  
Valentina Sabrekova ◽  
Maxim Korenyuga ◽  
Elena Konovalova ◽  
Natalia Rodionova
Keyword(s):  
Immune Response ◽  
Newcastle Disease ◽  
Laying Hens ◽  
Positive Influence ◽  
The Body ◽  
Infectious Bursal Disease ◽  
Post Vaccination ◽  
Before And After ◽  
Bursal Disease ◽  
Immunomodulatory Drug

Abstract Vaccination is a primary way to prevent infectious disease in poultry. The quality of immune response depends on the immune status of the body which, in turn, depends on many endogenous and exogenous factors. This study analyzed the effect of the immunomodulatory drug Azoxivet on the immune response in laying hens after vaccination against Newcastle Disease and Infectious Bursal Disease. There were 4 groups of Loman White cross laying hens (n=20). At age 120 days, all hens habitated in individual cages with an area of 0,15 m2. The conditions of keeping and feeding matched breed requirements. All groups were vaccinated against Newcastle Disease (NDV) (LaSota strain) and Infectious Bursal Disease (IBD) (Winterfield 2512 strain). All groups received Azoxivet (Az) at a dose of 0,3 mg/kg in water three times daily. Blood sera were collected weekly for serological studies using BioChek IBD and NDV test systems. The antibody level of all hens before and after vaccination: 1378 (IBD+Az) vs. 1674,93 (IBD) (P < 0,05), 5194,75 (NDV+Az) vs. 5612,87 (NDV) (P < 0,05). After one week of vaccination: 5931,25 (IBD+Az) vs. 5006,14 (IBD) (P < 0,05), 6207,58 (NDV+Az) vs. 5765,21 (NDV) (P < 0,05). Two weeks: 11086,00 (IBD+Az) vs. 10485,83 (IBD) (P < 0,05), 11255,25 (NDV+Az) vs. 8478,75 (NDV) (P < 0,05). Three weeks: 11478 (IBD+Az) vs. 8286 (IBD) (P < 0,05), 14725 (NDV+Az) vs. 12677 (NDV) (P < 0,05). Four weeks: 12999 (IBD+Az) vs. 1009,67 (IBD) (P < 0,05), 17399 (NDV+Az) vs. 16373,17 (NDV) (P < 0,05). Five weeks: 13601,15 (IBD+Az) vs. 9021,30 (IBD) (P < 0,05), 19671 (NDV+Az) vs. 16309 (NDV) (P < 0,05). Thus, Azaxul had a positive influence on the post-vaccination immune response in laying hens when used after Newcastle Disease and Infectious Bursal Disease vaccines. The results of the study can be used to improve disease prevention in poultry farming.

scholarly journals Histopathological And Immune Response Against Infectious Bursal Disease In Chickens Vaccinated Against Newcastle Disease

2013 ◽  
Vol 12 (1) ◽  
pp. 66 ◽  
Author(s):  
A.Z. AL Zubeedy
Keyword(s):  
Immune Response ◽  
Newcastle Disease ◽  
Elisa Test ◽  
Infectious Bursal Disease ◽  
High Antibody ◽  
Pathological Changes ◽  
Post Vaccination ◽  
Vaccination Programs ◽  
Bursal Disease ◽  
Antibody Titers

Two different vaccination programs against chicken infectious bursal disease (IBD) were compared. Results showed the first program including IBD vaccination at 8 and 16th day old as well as ND vaccination(live attenuated and inactivated types ) give high antibody titers at 21 days post vaccination with significantly difference (P≤0.0005) in comparison with the second program including only IBD vaccine . serological antibodies titer were determined to study the correlation between two different programs using ELISA test. pathological changes in vaccinated groups reveals mild & moderate lesions appear in liver, spleen and bursa of fabriciusKey word : IBD,ND , vaccination , ELISA test ,Broiler , histopathology .

scholarly journals Cellular immune response of infectious bursal disease and Newcastle disease vaccinations in broilers exposed to monochromatic lights

2011 ◽  
Vol 10 (46) ◽  
pp. 9528-9532 ◽  
Author(s):  
Sadrzadeh Avesta ◽  
Nikbakht Brujeni Gholamreza ◽  
Livi Masoud ◽  
Javad Nazari Mohammad ◽  
Tehrani Sharif Meysam ◽  
...  
Keyword(s):  
Immune Response ◽  
Newcastle Disease ◽  
Cellular Immune Response ◽  
Infectious Bursal Disease ◽  
Bursal Disease ◽  
Cellular Immune

scholarly journals Aflatoxicosis, infectious bursal disease and immune response to Newcastle disease vaccination in rural chickens

2005 ◽  
Vol 34 (4) ◽  
pp. 319-323 ◽  
Author(s):  
Maxwell O. Otim ◽  
G. Mukiibi-Muka ◽  
Henrik Christensen ◽  
Magne Bisgaard
Keyword(s):  
Immune Response ◽  
Newcastle Disease ◽  
Infectious Bursal Disease ◽  
Bursal Disease

scholarly journals The immune response of broiler chickens fed diets supplemented with Propolis and Digestarom under heat stress condition

2019 ◽  
Vol 42 (2) ◽  
pp. 33-40
Author(s):  
Hasanain shauqi H.
Keyword(s):  
Immune Response ◽  
Heat Stress ◽  
Newcastle Disease ◽  
Broiler Chickens ◽  
Infectious Bursal Disease ◽  
Stress Group ◽  
Lymphocyte Ratio ◽  
Bursal Disease ◽  
Antibody Titers ◽  
Group 3

                                                             Summary    This research was carried out to evaluate the effect of dietary supplementation  of a mixture of  propolis and phytogenic (Digestarom)on immune responses against Newcastle disease and infectious bursal disease , also Heterophil/lymphocyte ratios in vaccinated broiler under thermoneutral (maintained on usual heat program)and heat stress maintained in  )33 ± 2°C). total of three hundred, one-day-old broilers (Rose 308) chicks were distributed equally in two separated room, thermoneutral  groups and heat stress HS groups along the duration of the experiment (42)day, then each group subdivided in to five groups( 30 chicks for each )  as follow: (thermoneutral group and heat stress group )fed a basal diet supplemented with propolis (2g/kg of diet),(thermoneutral group 2and heat stress2)fed Digestarom(150mg/kg).( thermoneutral  group 3 and heat stress group 3) fed a mixture of (propolis2g/kg +Digestarom150mg/kg) and two control groups without additive. Antibody titers against Newcastle disease  and infectious bursal disease   were measured and Heterophil/lymphocyte  ratio was estimated. In heat stress  chickens the results revealed a significant decrease(P<0.05)in immune response with significant increased(P<0.05) in Heterophil/lymphocyte  ratio, while higher significant (P<0.05)in antibody titers with significant decrease (P<0.05) in Heterophil/lymphocyte  ratio was showed in all thermoneutral chickens but more significant in thermoneutral group 3 and heat stress group 3 groups were gave the best values in comparing with others groups. The role of Propolis or phytogenic on broiler health and immunity had already been reported, but in this study was reported the effects of their mixture on ameliorating  deleterious effects of heat stress.

APPLICATION OF SHIFTING ASSAY OF STANDARDIZED INDIRECT AGGLUTINATION (SSIA) FOR DETECTION OF ANTIGENS OF NEWCASTLE DISEASE AND INFECTIOUS BURSAL DISEASE VIRUSES IN CHICKEN FAECES

2013 ◽  
Vol 83 (5) ◽  
Author(s):  
Phạm Hồng Sơn ◽  
Phạm Hồng Kỳ ◽  
Nguyễn Thị Lan Hương ◽  
Phạm Thị Hồng Hà
Keyword(s):  
Newcastle Disease ◽  
Winter Season ◽  
Summer Season ◽  
Infectious Bursal Disease ◽  
Infection Rates ◽  
Faecal Samples ◽  
Infectious Bursal Disease Viruses ◽  
Bursal Disease ◽  
Long Time ◽  
Higher Sensitivity

. Using the method of shifting assay of standardized indirect agglutination (SSIA), the prevalence of Newcastle disease viruses (NDV) and infectious bursal disease viruses (IBDV) in chickens reared in several districts of Thua Thien Hue province in the Spring-Summer and Fall-Winter seasons was determined. In the Spring-Summer season of 2011, about 22.3% of the chickens were infected with NDV, in which A Luoi  accounted for the highest percentage of 25% of the infected chickens and Huong Thuy  the lowest  of 18.2%. Meanwhile, 36% of the same chickens were infected with IBDV, with the highest percentage (46.66%) also in A Luoi and the lowest (30.3%) also in Huong Thuy. The intensity of NDV infection in the Spring-Summer season in A Luoi and Phu Vang was highest (GMT = 1.45), and in Huong Thuy lowest (GMT = 1.31). In addition, in the Fall-Winter season, about 46% of the chickens were infected with NDV and 46.3% with IBDV in Huong Thuy and Phu Vang – two neighbouring districts of Hue City, in which NDV was detected in 54.4% of the chickens in Huong Thuy and 33.9% in Phu Vang. In contrast, IBDV was detected in 41.9% and 52.7% of the chickens respectively in the two districts. The infection was not inter-dependent. Methodically, although the differences in the infection rates were insignificant with the accuracy of 95%, faecal samples showed higher sensitivity in SSIA analyses for both cases of NDV and IBDV infection in comparision with mouth exudates. By SSIA method, results could be read clearly with unaided eyes for a long time after the performance, and it was also proven applicable for cases of haemagglutinating viruses if proper treatments for depletion of animal RBCs’ surface agglutinins could be applied.

scholarly journals Prevalence of poultry diseases in Gazipur district of Bangladesh

2016 ◽  
Vol 2 (1) ◽  
pp. 107-112 ◽  
Author(s):  
Md Kamrul Hassan ◽  
Md Humayun Kabir ◽  
Md Abdullah Al Hasan ◽  
Shobnom Sultana ◽  
Md Shohidul Islam Khokon ◽  
...  
Keyword(s):  
Newcastle Disease ◽  
Clinical Signs ◽  
Infectious Bursal Disease ◽  
Viral Diseases ◽  
Necrotic Enteritis ◽  
Age Group ◽  
Bacterial Diseases ◽  
Infectious Bronchitis ◽  
Prevalent Disease ◽  
Bursal Disease

This study was designed with a view to investigate the prevalence of poultry diseases in Gazipur district of Bangladesh. A total of 679 poultry birds (313 layers, 338 broilers and 28 cockrels) either dead or live were brought for diagnosis of diseases at Gazipur Sadar Upazilla Veterinary Hospital. The diseases were diagnosed on the basis of history, clinical signs and post-mortem findings. The diseases encountered in layers were bacterial diseases 52.29% (salmonellosis 38.56%, colibacillosis 6.7%, fowl cholera 4.79% and necrotic enteritis 1.60%), viral diseases 23.95% (avian influenza 2.56%, Newcastle disease 16.61%, infectious bronchitis 3.19% and avian leucosis 0.64%), mycoplasmal disease (mycoplasmosis 14.70%) and protozoal disease (coccidiosis 5.75%). Salmonellosis was most prevalent disease in age group of >20 weeks, while Newcastle disease most common in 8 to 20 weeks of age group. In case of broiler, bacterial diseases 28.99% (salmonellosis 21.30% and colibacillosis 7.69%), viral diseases 53.24% (infectious bursal disease 28.99%, Newcastle disease 8.87% and infectious bronchitis 15.38%), mycoplasmal disease (mycoplasmosis 7.1%) and protozoal disease (coccidiosis 6.5%). In cockrels, the most prevalent disease was colibacillosis 35.71% followed by salmonellosis 28.57%, Newcastle disease 14.28% and mycoplasmosis14.28%. So among the diseases, salmonellosis is most prevalent disease followed by infectious bursal disease and mycoplasmosis in different kinds of poultry of Gazipur district of Bangladesh.Asian J. Med. Biol. Res. March 2016, 2(1): 107-112

Sign in / Sign up

Export Citation Format

Share Document