scholarly journals Histopathological And Immune Response Against Infectious Bursal Disease In Chickens Vaccinated Against Newcastle Disease

2013 ◽  
Vol 12 (1) ◽  
pp. 66 ◽  
Author(s):  
A.Z. AL Zubeedy
Keyword(s):  
Immune Response ◽  
Newcastle Disease ◽  
Elisa Test ◽  
Infectious Bursal Disease ◽  
High Antibody ◽  
Pathological Changes ◽  
Post Vaccination ◽  
Vaccination Programs ◽  
Bursal Disease ◽  
Antibody Titers

Two different vaccination programs against chicken infectious bursal disease (IBD) were compared. Results showed the first program including IBD vaccination at 8 and 16th day old as well as ND vaccination(live attenuated and inactivated types ) give high antibody titers at 21 days post vaccination with significantly difference (P≤0.0005) in comparison with the second program including only IBD vaccine . serological antibodies titer were determined to study the correlation between two different programs using ELISA test. pathological changes in vaccinated groups reveals mild & moderate lesions appear in liver, spleen and bursa of fabriciusKey word : IBD,ND , vaccination , ELISA test ,Broiler , histopathology .

PSX-B-24 Influence of the immunomodulatory drug Azoxivet on the post-vaccination immune response in laying hens

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 269-269
Author(s):  
Valentina Sabrekova ◽  
Maxim Korenyuga ◽  
Elena Konovalova ◽  
Natalia Rodionova
Keyword(s):  
Immune Response ◽  
Newcastle Disease ◽  
Laying Hens ◽  
Positive Influence ◽  
The Body ◽  
Infectious Bursal Disease ◽  
Post Vaccination ◽  
Before And After ◽  
Bursal Disease ◽  
Immunomodulatory Drug

Abstract Vaccination is a primary way to prevent infectious disease in poultry. The quality of immune response depends on the immune status of the body which, in turn, depends on many endogenous and exogenous factors. This study analyzed the effect of the immunomodulatory drug Azoxivet on the immune response in laying hens after vaccination against Newcastle Disease and Infectious Bursal Disease. There were 4 groups of Loman White cross laying hens (n=20). At age 120 days, all hens habitated in individual cages with an area of 0,15 m2. The conditions of keeping and feeding matched breed requirements. All groups were vaccinated against Newcastle Disease (NDV) (LaSota strain) and Infectious Bursal Disease (IBD) (Winterfield 2512 strain). All groups received Azoxivet (Az) at a dose of 0,3 mg/kg in water three times daily. Blood sera were collected weekly for serological studies using BioChek IBD and NDV test systems. The antibody level of all hens before and after vaccination: 1378 (IBD+Az) vs. 1674,93 (IBD) (P < 0,05), 5194,75 (NDV+Az) vs. 5612,87 (NDV) (P < 0,05). After one week of vaccination: 5931,25 (IBD+Az) vs. 5006,14 (IBD) (P < 0,05), 6207,58 (NDV+Az) vs. 5765,21 (NDV) (P < 0,05). Two weeks: 11086,00 (IBD+Az) vs. 10485,83 (IBD) (P < 0,05), 11255,25 (NDV+Az) vs. 8478,75 (NDV) (P < 0,05). Three weeks: 11478 (IBD+Az) vs. 8286 (IBD) (P < 0,05), 14725 (NDV+Az) vs. 12677 (NDV) (P < 0,05). Four weeks: 12999 (IBD+Az) vs. 1009,67 (IBD) (P < 0,05), 17399 (NDV+Az) vs. 16373,17 (NDV) (P < 0,05). Five weeks: 13601,15 (IBD+Az) vs. 9021,30 (IBD) (P < 0,05), 19671 (NDV+Az) vs. 16309 (NDV) (P < 0,05). Thus, Azaxul had a positive influence on the post-vaccination immune response in laying hens when used after Newcastle Disease and Infectious Bursal Disease vaccines. The results of the study can be used to improve disease prevention in poultry farming.

scholarly journals The immune response of broiler chickens fed diets supplemented with Propolis and Digestarom under heat stress condition

2019 ◽  
Vol 42 (2) ◽  
pp. 33-40
Author(s):  
Hasanain shauqi H.
Keyword(s):  
Immune Response ◽  
Heat Stress ◽  
Newcastle Disease ◽  
Broiler Chickens ◽  
Infectious Bursal Disease ◽  
Stress Group ◽  
Lymphocyte Ratio ◽  
Bursal Disease ◽  
Antibody Titers ◽  
Group 3

                                                             Summary    This research was carried out to evaluate the effect of dietary supplementation  of a mixture of  propolis and phytogenic (Digestarom)on immune responses against Newcastle disease and infectious bursal disease , also Heterophil/lymphocyte ratios in vaccinated broiler under thermoneutral (maintained on usual heat program)and heat stress maintained in  )33 ± 2°C). total of three hundred, one-day-old broilers (Rose 308) chicks were distributed equally in two separated room, thermoneutral  groups and heat stress HS groups along the duration of the experiment (42)day, then each group subdivided in to five groups( 30 chicks for each )  as follow: (thermoneutral group and heat stress group )fed a basal diet supplemented with propolis (2g/kg of diet),(thermoneutral group 2and heat stress2)fed Digestarom(150mg/kg).( thermoneutral  group 3 and heat stress group 3) fed a mixture of (propolis2g/kg +Digestarom150mg/kg) and two control groups without additive. Antibody titers against Newcastle disease  and infectious bursal disease   were measured and Heterophil/lymphocyte  ratio was estimated. In heat stress  chickens the results revealed a significant decrease(P<0.05)in immune response with significant increased(P<0.05) in Heterophil/lymphocyte  ratio, while higher significant (P<0.05)in antibody titers with significant decrease (P<0.05) in Heterophil/lymphocyte  ratio was showed in all thermoneutral chickens but more significant in thermoneutral group 3 and heat stress group 3 groups were gave the best values in comparing with others groups. The role of Propolis or phytogenic on broiler health and immunity had already been reported, but in this study was reported the effects of their mixture on ameliorating  deleterious effects of heat stress.

scholarly journals Cellular immune response of infectious bursal disease and Newcastle disease vaccinations in broilers exposed to monochromatic lights

2011 ◽  
Vol 10 (46) ◽  
pp. 9528-9532 ◽  
Author(s):  
Sadrzadeh Avesta ◽  
Nikbakht Brujeni Gholamreza ◽  
Livi Masoud ◽  
Javad Nazari Mohammad ◽  
Tehrani Sharif Meysam ◽  
...  
Keyword(s):  
Immune Response ◽  
Newcastle Disease ◽  
Cellular Immune Response ◽  
Infectious Bursal Disease ◽  
Bursal Disease ◽  
Cellular Immune

scholarly journals Comparative Immunogenicity Evaluation of Two Commonly Used Infectious Bursal Disease Vaccines in Broiler Chickens in Ethiopia

2021 ◽  
Author(s):  
Likelesh Legese ◽  
Berhane Wakjira ◽  
Tsedale Teshome ◽  
Dereje Nigussie Woldemichael ◽  
Hika Waktole ◽  
...  
Keyword(s):  
Broiler Chickens ◽  
Immunological Response ◽  
Elisa Test ◽  
Infectious Bursal Disease ◽  
Differential Leukocyte Count ◽  
Endemic Diseases ◽  
Bursal Disease ◽  
Antibody Titers ◽  
Group 2 ◽  
Group 1

Infectious bursal disease (IBD) is one of the most endemic diseases of commercial poultry in Ethiopia. Vaccination has been practiced as the major means of IBD prevention and control. A study was conducted to determine and compare the immunogenicity of two commercially available IBD vaccines in broiler chicken with maternally derived antibody (MDA). Day-old chickens of 270 were randomly assigned to three groups, group 1 vaccinated with brand 1 vaccine at 7th and 19th days and group 2 with brand 2 vaccine at 15th and 22nd days while group 3 were kept as control. Six chickens were also randomly selected and bled on day 1 for differential leukocyte count (DLC) and determination of MDA. Representative chickens from each group were bled at 24th and 42nd days of age for antibody titration using the indirect ELISA test. DLC scores were determined in the 1st and 24th days. The result revealed highly significant differences (P = 0.001) between group 1 and group 2 in DLC at 24th days of age. Antibody titers against IBD were differed significantly (P = 0.02) at 24th and 42nd days of age in broilers vaccinated with brand 1 and brand 2 vaccines. It is concluded that although both brands of vaccine induce an adequate immunological response at the end of the experiment, brand 1 vaccine has shown significantly high antibody titers against the IBDV and DLC than brand 2.

Different Regimes for Challenge Instigation against Newcastle Disease Virus in Layer Birds

2018 ◽  
Vol 52 (1-4) ◽  
pp. 10-21
Author(s):  
MR Rahman ◽  
NA Rumi ◽  
MK Hossain ◽  
MS Rahman ◽  
MG Rahman ◽  
...  
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Serological Test ◽  
Tap Water ◽  
Serum Antibody ◽  
Age Groups ◽  
Post Vaccination ◽  
Vaccination Programs ◽  
Antibody Titers

Newcastle disease is a highly contagious disease of poultry and causes huge economic loss in Bangladesh. In the study, the efficacy of different vaccination programs against Newcastle disease virus was performed to examine duration and level of antibody in two layer farms with different diluents. The experiment was carried out in Dinajpur district and serological test was performed in the Department of Microbiology, Hajee Mohammad Danesh Science and Technology University, Dinajpur during the period of July, 2017 to December, 2017. A total of 200 blood samples were randomly collected from different age groups of layer birds which were vaccinated with commercially available two live and one killed vaccine namely Avi ND LaSota, CEVAC NEW L and ITA-New (ND). Pre-vaccination serum antibody titers (Mean ± SD) of group A birds were 5.97±0.75. Firstly, birds were vaccinated with Avi ND LASOTA® vaccine, and CEVAC® NEW L vaccine. MASTERBLUE powder and ADVANCE NON-FAT were used as diluents in vaccination. After 40 days of post-vaccination, sera samples were procured and showed serum antibody titer (Mean ± SD) 7.0 ± 0.93. In case of farm-B, before vaccination antibody titers levels against NDV were Mean ± SD 5.85±0.75. Birds of farm-B were vaccinated with Avi ND LaSota® vaccine. After 40 days of post-vaccination, titer was Mean ± SD 6.7 ± 0.93. Then birds were vaccinated with ITA-New (ND) ® which were killed vaccine. After 40 days of post-vaccination, the titer was Mean ± SD 8.15± 0.93. MASTERBLUE powder and ADVANCE NON-FAT are suitable diluents to be used in vaccination against Newcastle disease because tap water may inactivate the vaccine due to its impurity in addition to containing higher level of chlorine and even the type of pipes or vessels used to distribute the drinking water. The results showed that the level of protection of vaccinated birds was satisfactory.

scholarly journals Aflatoxicosis, infectious bursal disease and immune response to Newcastle disease vaccination in rural chickens

2005 ◽  
Vol 34 (4) ◽  
pp. 319-323 ◽  
Author(s):  
Maxwell O. Otim ◽  
G. Mukiibi-Muka ◽  
Henrik Christensen ◽  
Magne Bisgaard
Keyword(s):  
Immune Response ◽  
Newcastle Disease ◽  
Infectious Bursal Disease ◽  
Bursal Disease

scholarly journals EVALUATION OF ANATOMOPATHOLOGICAL, SEROLOGICAL, IMMUNOLOGICAL RESPONSES AND PROTECTION IN BROILERS VACCINATED WITH LIVE INFECTIOUS BURSAL DISEASE VACCINES

2007 ◽  
Vol 74 (3) ◽  
pp. 219-226
Author(s):  
M. Nishizawa ◽  
A.C. Paulillo ◽  
A. Bernardino ◽  
A.C. Alessi ◽  
S. Sayd ◽  
...  
Keyword(s):  
Image Processing ◽  
Newcastle Disease ◽  
Virulent Strain ◽  
Relative Weight ◽  
Elisa Test ◽  
Infectious Bursal Disease ◽  
Immunological Responses ◽  
The Third ◽  
Histological Score ◽  
Bursal Disease

ABSTRACT The study was divided into three experiments. In the first one, broilers were distributed into six groups and vaccinated against infectious bursal disease at 14 days of age: T1-not vaccinated, T2-Lukert1 (intermediate), T3-Lukert2 (intermediate plus), T4-228E, T5-V877 and T6-Winterfield 2512 (“hot” strains). Bursas of Fabricius (BF) were collected at 17, 21, 28 and 35 days to measure BF relative weight (BFRW), diameter, histological examination and image processing analysis (IPA). At one, 14, 21, 28 and 35 days of age, samples of blood taken from eight birds from each group for serology analysis by ELISA test. Hot strains vaccines induced reduction of BFRW and BF diameter, higher histological score lesion degree, more lymphocyte depletion on the BF follicles and higher IBD antibody titer. In the second experiment, 16 birds from groups T1 to T6 were isolated and challenged with a very virulent strain of IBDV (vvIBDV) at 25 days of age. Only groups T4, T5 and T6 were totally protected against vvIBDV challenge. In the third experiment, the immunosuppressive potential of each vaccine was determined by examining the ability of IBDVvaccinated birds to respond to Newcastle disease (ND) vaccination and challenge. None of the vaccines was found to be immunodepressive.

Sign in / Sign up

Export Citation Format

Share Document