scholarly journals 154 Effect of substitution of ZnO by organic acids, medium chain fatty acids monoglycerides and essential oils in high or low protein diets in piglets.

2018 ◽  
Vol 96 (suppl_3) ◽  
pp. 289-289
Author(s):  
L Miranda ◽  
A Fuentetaja ◽  
J Gálvez ◽  
J Lozano ◽  
P Medel
Keyword(s):  
Fatty Acids ◽  
Organic Acids ◽  
Essential Oils ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Low Protein ◽  
Protein Diets ◽  
Chain Fatty Acids

scholarly journals 310 Using synergistic antibacterial combinations based on vegetable essential oils to replace feeding antibiotics

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 10-10
Author(s):  
yanping Hu ◽  
Jie Huang ◽  
Zhongxin Zhou
Keyword(s):  
Fatty Acids ◽  
Citric Acid ◽  
Organic Acids ◽  
Essential Oils ◽  
Octanoic Acid ◽  
Water Solubility ◽  
Enterotoxigenic Escherichia Coli ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Chain Fatty Acids

Abstract Vegetable essential oils, medium-chain fatty acids and organic acids have great potential in the development of alternatives to feeding antibiotics, but many problems in practice limit their application, such as irritating odor, poor water solubility, easy oxidation and volatility. In this study, we found that vegetable essential oils (carcilol, cinnamaldehyde, terptol-4) and medium chain fatty acids (octanoic acid and nonanoic acid) or organic acids (citric acid) had significantly synergistic bactericidal effects on enterotoxigenic Escherichia coli and Salmonella enteribacilli, which are both common pathogens causing piglets diarrhea. Furthermore, we also compared the tolerances of the enterotoxigenic Escherichia coli against plant essential oils (cinnamaldehyde, carcocol, 4- terptol), medium chain fatty acids (octanoic acid and nonylic acid), organic acids (citric acid), and commonly used antibiotic growth promoter (gentamycin sulfate). They were in vitro cultured with ETEC strain for 30 consecutive generations and the minimum inhibitory concentration (MIC) value was detected. The results showed that the MIC values of carvonol, cinnamaldehyde, terpineol-4, octanoic acid, nonylic acid, and citric acid against the ETEC bacteria increased by 5, 3, 1, 0.3, 0.4 and 0 times. But the MIC value of gentamicin against ETEC bacteria increased, in the 20th generation, by more than 64 times. In conclusions, the synergistic bactericidal combination based on the plant essential oil and middle chain fatty acid or organic acid may be a better strategy to replace feeding antibiotics because their synergistic bactericidal combination can greatly reduce the effective concentration of plant essential oil, medium chain fatty acid and organic acid, thus alleviating to a certain extent the shortcomings of unstable effects caused by the irritating odor, the poor water solubility, easy oxidation and volatility. The synergistic bactericidal combination based on plant essential oils are also relatively difficult to cause bacterial tolerance and alleviate bacterial resistance to a certain extent.

Effects of a matrix-coated organic acids and medium-chain fatty acids blend on performance, and in vitro fecal noxious gas emissions in growing pigs fed in-feed antibiotic-free diets

2018 ◽  
Vol 98 (3) ◽  
pp. 433-442 ◽  
Author(s):  
M.M. Hossain ◽  
B. Jayaraman ◽  
S.C. Kim ◽  
K.Y. Lee ◽  
I.H. Kim ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Organic Acids ◽  
Growth Efficiency ◽  
Growing Pigs ◽  
Growth Promoters ◽  
Gas Emissions ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Chain Fatty Acids

This study evaluated the efficacy of a matrix-coated organic acids and medium-chain fatty acids blend (MCOFA) in growing pigs. Ninety six pigs [(Yorkshire × Landrace) × Duroc] with an average body weight (BW) of 47.71 ± 3.73 kg were used in a 6 wk experiment. Pigs were allotted to diets containing 0 or 2 g kg−1 of MCOFA, and 0 or 2.5 g kg−1 of antibiotic growth promoters (AGP) according to a 2 × 2 factorial arrangement of treatments. Pigs fed diets supplemented with MCOFA had improved growth efficiency compared with those fed a diet without MCOFA (P < 0.05). Pigs receiving the diets supplemented with both AGP and MCOFA had higher apparent total tract digestibility of crude protein, dry matter, fat, and gross energy (P < 0.05). Pigs fed AGP × MCOFA diet had increased serum urea nitrogen (P < 0.05). Pigs fed diets supplemented with AGP had reduced fecal ammonia (NH3) gas emissions compared with those fed without AGP (P < 0.05). Moreover, pigs fed diets supplemented with MCOFA had reduced fecal NH3 and acetic acid gas emissions compared with those fed without MCOFA (P < 0.05). In conclusion, dietary supplementation with MCOFA improved performance in growing pigs.

Effect of Organic Acids on Salmonella Shedding and Colonization in Pigs on a Farm with High Salmonella Prevalence

2016 ◽  
Vol 79 (1) ◽  
pp. 51-58 ◽  
Author(s):  
G. RASSCHAERT ◽  
J. MICHIELS ◽  
M. TAGLIABUE ◽  
J. MISSOTTEN ◽  
S. DE SMET ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Lymph Nodes ◽  
Organic Acids ◽  
Commercial Products ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Slaughter Age ◽  
Combined Feed ◽  
Fattening Pigs ◽  
Chain Fatty Acids

ABSTRACT This study builds on the results of a previous study in which six commercial feed products based on organic acids were evaluated with respect to Salmonella contamination of piglets in an artificially challenged seeder model. In the present study, the efficacy of three of these commercial products was assessed for Salmonella reduction in fattening pigs on one closed farm with a natural high Salmonella prevalence. In each of four fattening compartments, one of the following feed treatments was evaluated during two consecutive fattening rounds: (i) butyric acid (active ingredients at 1.3 kg/ton of feed; supplement A1), (ii) a combination of short-chain organic acids (mixture of free acids and salts) and natural extracts (2.92 kg/ton; supplement A4), (iii) a 1:1 blend of two commercial products consisting of medium-chain fatty acids, lactic acid, and oregano oil (3.71 kg/ton; supplement A5+A6), and (iv) a control feed. On the farm, the Salmonella status of the fattening pigs was evaluated by taking fecal samples twice during the fattening period. At the slaughterhouse, samples were collected from the cecal contents and the ileocecal lymph nodes. Salmonella isolates were serotyped and characterized by pulsed-field gel electrophoresis. This farm had a particularly high number of pigs shedding Salmonella with a wide variety of sero- and pulsotypes. Only the feed blend based on the medium-chain fatty acids was able to significantly reduce Salmonella prevalence both on the farm and at the slaughterhouse. With this combined supplement, the Salmonella reduction in the feces at slaughter age, in cecal contents at slaughter, and the lymph nodes was 50, 36, and 67%, respectively, compared with the control animals. This promising finding calls for further investigation including cost-efficiency of this combined feed product and its effect on the animals.

scholarly journals PSVI-11 Evaluation of essential oils and short-medium chain fatty acids in-vitro and in-vivo on performance of nursery pigs

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 207-207
Author(s):  
Kory Moran ◽  
Jan Dirk van der Klis ◽  
Glen Almond ◽  
Eric van Heugten
Keyword(s):  
Fatty Acids ◽  
Essential Oils ◽  
Synergistic Effects ◽  
Synergistic Activity ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Broth Microdilution Method ◽  
Chain Fatty Acids

Abstract This study evaluated the anti-bacterial effects of two essential oils blends (EO1: garlic-derived allyl disulfide+d-limonene; EO2: garlic-derived allyl disulfide+γ-terpinene) and three mixtures of short-medium chain fatty acids (S-MCFA1: monolaurin enriched+C4-C12 mixture; S-MCFA2: monolaurin; S-MCFA3: monobutyrin enriched+C4-C12 mixture). In Exp. 1, the Minimum Inhibitory Concentration test (MIC; broth microdilution method using CLSI Guidelines) determined the in-vitro synergistic activity of six combinations: 1) EO1+S-MCFA1; 2) EO1+S-MCFA2; 3) EO1+S-MCFA3; 4) EO2+S-MCFA1; 5) EO2+S-MCFA2; 6) EO2+S-MCFA3; against E.coli F18 and F4. Results suggest synergistic effects for EO1+S-MCFA1, EO2+S-MCFA1, and EO2+S-MCFA2 against both E.coli strains (Tables 1). Exp. 2 evaluated supplementation of EO2 and S-MCFA1 on growth performance of weaned pigs housed in a non-sanitary environment. Pigs (n = 600; BW=7.46 ± 0.57 kg) were used in a 35-day trial. Pigs were blocked by BW and balanced by sex within pens and placed into 60 pens (10 pigs/pen). Pigs were fed a 3-phase feeding program, with periods being 7, 14, and 14 d, respectively. Dietary treatments were: A: control, B: control+0.05% EO2; C: control+0.05% EO2 + 0.075% S-MCFA1; D: control+0.05% EO2 + 0.15% S-MCFA1; E: control+0.15% S-MCFA1. Data were analyzed as RCBD in a 2×2 + 1 factorial arrangement of treatments. No interactions between EO2 and S-MCFA1 were observed on performance. During Phase 2, ADFI and ADG tended to decrease when EO2 was supplemented (536 vs 509; 358 vs 336 g/d, respectively; PE. coli. However, under the challenging conditions of this experiment, only EO2 improved feed efficiency during Phase 3.

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