scholarly journals Drinking water supplement containing organic acids and medium chain fatty acids induces significant changes in the intestinal microbiota and lowers incidence of diarrhoea of piglets post-weaning

2011 ◽  
Author(s):  
Ajay Awati ◽  
C. H. M. Smits ◽  
H. van Dam ◽  
J. Meijer ◽  
O. Pérez Gutiérrez ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Drinking Water ◽  
Organic Acids ◽  
Intestinal Microbiota ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Chain Fatty Acids

scholarly journals Application of medium-chain fatty acids in drinking water increases Campylobacter jejuni colonization threshold in broiler chicks

2012 ◽  
Vol 91 (7) ◽  
pp. 1733-1738 ◽  
Author(s):  
D. Hermans ◽  
A. Martel ◽  
A. Garmyn ◽  
M. Verlinden ◽  
M. Heyndrickx ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Drinking Water ◽  
Campylobacter Jejuni ◽  
Broiler Chicks ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Chain Fatty Acids

Nutritional and physiological role of medium-chain triglycerides and medium-chain fatty acids in piglets

2011 ◽  
Vol 12 (1) ◽  
pp. 83-93 ◽  
Author(s):  
J. Zentek ◽  
S. Buchheit-Renko ◽  
F. Ferrara ◽  
W. Vahjen ◽  
A. G. Van Kessel ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Intestinal Microbiota ◽  
Animal Species ◽  
Negative Impact ◽  
Physiological Role ◽  
Feed Additives ◽  
Medium Chain Triglycerides ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Chain Fatty Acids

AbstractMedium-chain fatty acids (MCFAs) are found at higher levels in milk lipids of many animal species and in the oil fraction of several plants, including coconuts, palm kernels and certainCupheaspecies. Medium-chain triglycerides (MCTs) and fatty acids are efficiently absorbed and metabolized and are therefore used for piglet nutrition. They may provide instant energy and also have physiological benefits beyond their energetic value contributing to several findings of improved performance in piglet-feeding trials. MCTs are effectively hydrolyzed by gastric and pancreatic lipases in the newborn and suckling young, allowing rapid provision of energy for both enterocytes and intermediary hepatic metabolism. MCFAs affect the composition of the intestinal microbiota and have inhibitory effects on bacterial concentrations in the digesta, mainly onSalmonellaand coliforms. However, most studies have been performedin vitroup to now andin vivodata in pigs are still scarce. Effects on the gut-associated and general immune function have been described in several animal species, but they have been less studied in pigs. The addition of up to 8% of a non-esterified MCFA mixture in feed has been described, but due to the sensory properties this can have a negative impact on feed intake. This may be overcome by using MCTs, allowing dietary inclusion rates up to 15%. Feeding sows with diets containing 15% MCTs resulted in a lower mortality of newborns and better development, particularly of underweight piglets. In conclusion, MCFAs and MCTs offer advantages for the improvement of energy supply and performance of piglets and may stabilize the intestinal microbiota, expanding the spectrum of feed additives supporting piglet health in the post-weaning period.

Effects of a matrix-coated organic acids and medium-chain fatty acids blend on performance, and in vitro fecal noxious gas emissions in growing pigs fed in-feed antibiotic-free diets

2018 ◽  
Vol 98 (3) ◽  
pp. 433-442 ◽  
Author(s):  
M.M. Hossain ◽  
B. Jayaraman ◽  
S.C. Kim ◽  
K.Y. Lee ◽  
I.H. Kim ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Organic Acids ◽  
Growth Efficiency ◽  
Growing Pigs ◽  
Growth Promoters ◽  
Gas Emissions ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Chain Fatty Acids

This study evaluated the efficacy of a matrix-coated organic acids and medium-chain fatty acids blend (MCOFA) in growing pigs. Ninety six pigs [(Yorkshire × Landrace) × Duroc] with an average body weight (BW) of 47.71 ± 3.73 kg were used in a 6 wk experiment. Pigs were allotted to diets containing 0 or 2 g kg−1 of MCOFA, and 0 or 2.5 g kg−1 of antibiotic growth promoters (AGP) according to a 2 × 2 factorial arrangement of treatments. Pigs fed diets supplemented with MCOFA had improved growth efficiency compared with those fed a diet without MCOFA (P < 0.05). Pigs receiving the diets supplemented with both AGP and MCOFA had higher apparent total tract digestibility of crude protein, dry matter, fat, and gross energy (P < 0.05). Pigs fed AGP × MCOFA diet had increased serum urea nitrogen (P < 0.05). Pigs fed diets supplemented with AGP had reduced fecal ammonia (NH3) gas emissions compared with those fed without AGP (P < 0.05). Moreover, pigs fed diets supplemented with MCOFA had reduced fecal NH3 and acetic acid gas emissions compared with those fed without MCOFA (P < 0.05). In conclusion, dietary supplementation with MCOFA improved performance in growing pigs.

Effect of Organic Acids on Salmonella Shedding and Colonization in Pigs on a Farm with High Salmonella Prevalence

2016 ◽  
Vol 79 (1) ◽  
pp. 51-58 ◽  
Author(s):  
G. RASSCHAERT ◽  
J. MICHIELS ◽  
M. TAGLIABUE ◽  
J. MISSOTTEN ◽  
S. DE SMET ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Lymph Nodes ◽  
Organic Acids ◽  
Commercial Products ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Slaughter Age ◽  
Combined Feed ◽  
Fattening Pigs ◽  
Chain Fatty Acids

ABSTRACT This study builds on the results of a previous study in which six commercial feed products based on organic acids were evaluated with respect to Salmonella contamination of piglets in an artificially challenged seeder model. In the present study, the efficacy of three of these commercial products was assessed for Salmonella reduction in fattening pigs on one closed farm with a natural high Salmonella prevalence. In each of four fattening compartments, one of the following feed treatments was evaluated during two consecutive fattening rounds: (i) butyric acid (active ingredients at 1.3 kg/ton of feed; supplement A1), (ii) a combination of short-chain organic acids (mixture of free acids and salts) and natural extracts (2.92 kg/ton; supplement A4), (iii) a 1:1 blend of two commercial products consisting of medium-chain fatty acids, lactic acid, and oregano oil (3.71 kg/ton; supplement A5+A6), and (iv) a control feed. On the farm, the Salmonella status of the fattening pigs was evaluated by taking fecal samples twice during the fattening period. At the slaughterhouse, samples were collected from the cecal contents and the ileocecal lymph nodes. Salmonella isolates were serotyped and characterized by pulsed-field gel electrophoresis. This farm had a particularly high number of pigs shedding Salmonella with a wide variety of sero- and pulsotypes. Only the feed blend based on the medium-chain fatty acids was able to significantly reduce Salmonella prevalence both on the farm and at the slaughterhouse. With this combined supplement, the Salmonella reduction in the feces at slaughter age, in cecal contents at slaughter, and the lymph nodes was 50, 36, and 67%, respectively, compared with the control animals. This promising finding calls for further investigation including cost-efficiency of this combined feed product and its effect on the animals.

scholarly journals 310 Using synergistic antibacterial combinations based on vegetable essential oils to replace feeding antibiotics

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 10-10
Author(s):  
yanping Hu ◽  
Jie Huang ◽  
Zhongxin Zhou
Keyword(s):  
Fatty Acids ◽  
Citric Acid ◽  
Organic Acids ◽  
Essential Oils ◽  
Octanoic Acid ◽  
Water Solubility ◽  
Enterotoxigenic Escherichia Coli ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Chain Fatty Acids

Abstract Vegetable essential oils, medium-chain fatty acids and organic acids have great potential in the development of alternatives to feeding antibiotics, but many problems in practice limit their application, such as irritating odor, poor water solubility, easy oxidation and volatility. In this study, we found that vegetable essential oils (carcilol, cinnamaldehyde, terptol-4) and medium chain fatty acids (octanoic acid and nonanoic acid) or organic acids (citric acid) had significantly synergistic bactericidal effects on enterotoxigenic Escherichia coli and Salmonella enteribacilli, which are both common pathogens causing piglets diarrhea. Furthermore, we also compared the tolerances of the enterotoxigenic Escherichia coli against plant essential oils (cinnamaldehyde, carcocol, 4- terptol), medium chain fatty acids (octanoic acid and nonylic acid), organic acids (citric acid), and commonly used antibiotic growth promoter (gentamycin sulfate). They were in vitro cultured with ETEC strain for 30 consecutive generations and the minimum inhibitory concentration (MIC) value was detected. The results showed that the MIC values of carvonol, cinnamaldehyde, terpineol-4, octanoic acid, nonylic acid, and citric acid against the ETEC bacteria increased by 5, 3, 1, 0.3, 0.4 and 0 times. But the MIC value of gentamicin against ETEC bacteria increased, in the 20th generation, by more than 64 times. In conclusions, the synergistic bactericidal combination based on the plant essential oil and middle chain fatty acid or organic acid may be a better strategy to replace feeding antibiotics because their synergistic bactericidal combination can greatly reduce the effective concentration of plant essential oil, medium chain fatty acid and organic acid, thus alleviating to a certain extent the shortcomings of unstable effects caused by the irritating odor, the poor water solubility, easy oxidation and volatility. The synergistic bactericidal combination based on plant essential oils are also relatively difficult to cause bacterial tolerance and alleviate bacterial resistance to a certain extent.

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